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Items: 33

1.

Functional role of miR-148a in oropharyngeal cancer: influence on pregnane X receptor and P-glycoprotein expression.

Reuter T, Herold-Mende C, Dyckhoff G, Rigalli JP, Weiss J.

J Recept Signal Transduct Res. 2019 Oct-Dec;39(5-6):451-459. doi: 10.1080/10799893.2019.1694541. Epub 2019 Nov 27.

PMID:
31771390
2.

Inhibition of multidrug resistance-associated protein 2 (MRP2) activity by the contraceptive nomegestrol acetate in HepG2 and Caco-2 cells.

Tocchetti GN, Domínguez CJ, Zecchinati F, Arana MR, Ruiz ML, Villanueva SSM, Mottino AD, Weiss J, Rigalli JP.

Eur J Pharm Sci. 2018 Sep 15;122:205-213. doi: 10.1016/j.ejps.2018.07.017. Epub 2018 Jul 6.

PMID:
29981893
3.

Human papilloma virus (HPV) 18 proteins E6 and E7 up-regulate ABC transporters in oropharyngeal carcinoma. Involvement of the nonsense-mediated decay (NMD) pathway.

Rigalli JP, Reichel M, Tocchetti GN, Reuter T, Dyckhoff G, Herold-Mende C, Weiss J.

Cancer Lett. 2018 Aug 1;428:69-76. doi: 10.1016/j.canlet.2018.04.036. Epub 2018 Apr 30.

PMID:
29715486
4.

Biphasic modulation of cAMP levels by the contraceptive nomegestrol acetate. Impact on P-glycoprotein expression and activity in hepatic cells.

Tocchetti GN, Domínguez CJ, Zecchinati F, Arana MR, Ruiz ML, Villanueva SSM, Weiss J, Mottino AD, Rigalli JP.

Biochem Pharmacol. 2018 Aug;154:118-126. doi: 10.1016/j.bcp.2018.04.023. Epub 2018 Apr 21.

PMID:
29684377
5.

The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma.

Rigalli JP, Reichel M, Reuter T, Tocchetti GN, Dyckhoff G, Herold-Mende C, Theile D, Weiss J.

PLoS One. 2018 Feb 22;13(2):e0193242. doi: 10.1371/journal.pone.0193242. eCollection 2018.

6.

ABC Transporters: Regulation and Association with Multidrug Resistance in Hepatocellular Carcinoma and Colorectal Carcinoma.

Ceballos MP, Rigalli JP, Ceré LI, Semeniuk M, Catania VA, Ruiz ML.

Curr Med Chem. 2019;26(7):1224-1250. doi: 10.2174/0929867325666180105103637. Review.

PMID:
29303075
7.

The phytoestrogens daidzein and equol inhibit the drug transporter BCRP/ABCG2 in breast cancer cells: potential chemosensitizing effect.

Rigalli JP, Scholz PN, Tocchetti GN, Ruiz ML, Weiss J.

Eur J Nutr. 2019 Feb;58(1):139-150. doi: 10.1007/s00394-017-1578-9. Epub 2017 Nov 3.

PMID:
29101532
8.

Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-D-glucuronide in rat intestine and Caco-2 cells.

Tocchetti GN, Arias A, Arana MR, Rigalli JP, Domínguez CJ, Zecchinati F, Ruiz ML, Villanueva SSM, Mottino AD.

Arch Toxicol. 2018 Feb;92(2):777-788. doi: 10.1007/s00204-017-2092-9. Epub 2017 Oct 20.

PMID:
29052767
9.

Modulation of ABC Transporters by Nuclear Receptors: Physiological, Pathological and Pharmacological Aspects.

Rigalli JP, Tocchetti GN, Weiss J.

Curr Med Chem. 2019;26(7):1079-1112. doi: 10.2174/0929867324666170920141707. Review.

PMID:
28933287
10.

Glucagon-like peptide 2 prevents down-regulation of intestinal multidrug resistance-associated protein 2 and P-glycoprotein in endotoxemic rats.

Arana MR, Tocchetti GN, Zecchinati F, Londero AS, Dominguez C, Perdomo V, Rigalli JP, Villanueva SSM, Mottino AD.

Toxicology. 2017 Sep 1;390:22-31. doi: 10.1016/j.tox.2017.08.007. Epub 2017 Aug 23.

PMID:
28842383
11.

Intestinal multidrug resistance-associated protein 2 is down-regulated in fructose-fed rats.

Londero AS, Arana MR, Perdomo VG, Tocchetti GN, Zecchinati F, Ghanem CI, Ruiz ML, Rigalli JP, Mottino AD, García F, Villanueva SSM.

J Nutr Biochem. 2017 Feb;40:178-186. doi: 10.1016/j.jnutbio.2016.11.002. Epub 2016 Nov 9.

PMID:
27915161
12.

Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis.

Lambertucci F, Motiño O, Villar S, Rigalli JP, de Luján Alvarez M, Catania VA, Martín-Sanz P, Carnovale CE, Quiroga AD, Francés DE, Ronco MT.

Toxicol Appl Pharmacol. 2017 Jan 15;315:12-22. doi: 10.1016/j.taap.2016.11.015. Epub 2016 Nov 27.

PMID:
27899278
13.

Up-regulation of ATP-binding cassette transporters in the THP-1 human macrophage cell line by the antichagasic benznidazole.

Perdomo VG, Rigalli JP, Luquita MG, Pellegrino JM, Ruiz ML, Catania VA.

Mem Inst Oswaldo Cruz. 2016 Nov;111(11):707-711. doi: 10.1590/0074-02760160080. Epub 2016 Oct 24.

14.

The trypanocidal benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2).

Rigalli JP, Perdomo VG, Ciriaci N, Francés DE, Ronco MT, Bataille AM, Ghanem CI, Ruiz ML, Manautou JE, Catania VA.

Toxicol Appl Pharmacol. 2016 Aug 1;304:90-8. doi: 10.1016/j.taap.2016.05.007. Epub 2016 May 12.

15.

Modulation of expression and activity of intestinal multidrug resistance-associated protein 2 by xenobiotics.

Tocchetti GN, Rigalli JP, Arana MR, Villanueva SSM, Mottino AD.

Toxicol Appl Pharmacol. 2016 Jul 15;303:45-57. doi: 10.1016/j.taap.2016.05.002. Epub 2016 May 4. Review.

PMID:
27155371
16.

Physiological and pathophysiological factors affecting the expression and activity of the drug transporter MRP2 in intestine. Impact on its function as membrane barrier.

Arana MR, Tocchetti GN, Rigalli JP, Mottino AD, Villanueva SS.

Pharmacol Res. 2016 Jul;109:32-44. doi: 10.1016/j.phrs.2016.04.014. Epub 2016 Apr 22. Review.

PMID:
27109321
17.

Modulation of Expression and Activity of ABC Transporters by the Phytoestrogen Genistein. Impact on Drug Disposition.

Rigalli JP, Ciriaci N, Mottino AD, Catania VA, Ruiz ML.

Curr Med Chem. 2016;23(13):1370-89. Review.

PMID:
27048380
18.

The phytoestrogen genistein enhances multidrug resistance in breast cancer cell lines by translational regulation of ABC transporters.

Rigalli JP, Tocchetti GN, Arana MR, Villanueva SS, Catania VA, Theile D, Ruiz ML, Weiss J.

Cancer Lett. 2016 Jun 28;376(1):165-72. doi: 10.1016/j.canlet.2016.03.040. Epub 2016 Mar 24.

PMID:
27033456
19.

Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinoma.

Reuter T, Warta R, Theile D, Meid AD, Rigalli JP, Mogler C, Herpel E, Grabe N, Lahrmann B, Plinkert PK, Herold-Mende C, Dyckhoff G, Haefeli WE, Weiss J.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1141-50. doi: 10.1007/s00210-015-1150-1. Epub 2015 Jul 4.

PMID:
26141049
20.

Coordinated induction of GST and MRP2 by cAMP in Caco-2 cells: Role of protein kinase A signaling pathway and toxicological relevance.

Arana MR, Tocchetti GN, Domizi P, Arias A, Rigalli JP, Ruiz ML, Luquita MG, Banchio C, Mottino AD, Villanueva SSM.

Toxicol Appl Pharmacol. 2015 Sep 1;287(2):178-190. doi: 10.1016/j.taap.2015.06.003. Epub 2015 Jun 3.

PMID:
26049102
21.

Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicity.

Rigalli JP, Ciriaci N, Arias A, Ceballos MP, Villanueva SS, Luquita MG, Mottino AD, Ghanem CI, Catania VA, Ruiz ML.

PLoS One. 2015 Mar 17;10(3):e0119502. doi: 10.1371/journal.pone.0119502. eCollection 2015.

22.

Fluoride increases superoxide production and impairs the respiratory chain in ROS 17/2.8 osteoblastic cells.

Fina BL, Lombarte M, Rigalli JP, Rigalli A.

PLoS One. 2014 Jun 25;9(6):e100768. doi: 10.1371/journal.pone.0100768. eCollection 2014.

23.

Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity.

Arias A, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Perdomo VG, Vore M, Catania VA, Mottino AD.

Toxicology. 2014 Jun 5;320:46-55. doi: 10.1016/j.tox.2014.03.007. Epub 2014 Mar 28.

PMID:
24685904
24.

Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma.

Theile D, Gal Z, Warta R, Rigalli JP, Lahrmann B, Grabe N, Herold-Mende C, Dyckhoff G, Weiss J.

Cancer Biol Ther. 2014 Apr;15(4):436-42. doi: 10.4161/cbt.27632. Epub 2014 Jan 21.

25.

Modulation of biotransformation systems and ABC transporters by benznidazole in rats.

Perdomo VG, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Echenique CG, Catania VA.

Antimicrob Agents Chemother. 2013 Oct;57(10):4894-902. doi: 10.1128/AAC.02531-12. Epub 2013 Jul 22.

26.

Estrogen receptor-α mediates human multidrug resistance associated protein 3 induction by 17α-ethynylestradiol. Role of activator protein-1.

Ruiz ML, Rigalli JP, Arias A, Villanueva SS, Banchio C, Vore M, Mottino AD, Catania VA.

Biochem Pharmacol. 2013 Aug 1;86(3):401-9. doi: 10.1016/j.bcp.2013.05.025. Epub 2013 Jun 6.

PMID:
23747343
27.

Minor role of pregnane-x-receptor for acquired multidrug resistance in head and neck squamous cell carcinoma in vitro.

Rigalli JP, Reuter T, Herold-Mende C, Dyckhoff G, Haefeli WE, Weiss J, Theile D.

Cancer Chemother Pharmacol. 2013 May;71(5):1335-43. doi: 10.1007/s00280-013-2133-x. Epub 2013 Mar 12.

PMID:
23479137
28.

Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptor.

Rigalli JP, Perdomo VG, Luquita MG, Villanueva SS, Arias A, Theile D, Weiss J, Mottino AD, Ruiz ML, Catania VA.

PLoS Negl Trop Dis. 2012;6(12):e1951. doi: 10.1371/journal.pntd.0001951. Epub 2012 Dec 13.

29.

Induction of hepatic multidrug resistance-associated protein 3 by ethynylestradiol is independent of cholestasis and mediated by estrogen receptor.

Ruiz ML, Rigalli JP, Arias A, Villanueva S, Banchio C, Vore M, Mottino AD, Catania VA.

Drug Metab Dispos. 2013 Feb;41(2):275-80. doi: 10.1124/dmd.112.047357. Epub 2012 Oct 17.

30.

Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene.

Villanueva SS, Perdomo VG, Ruiz ML, Rigalli JP, Arias A, Luquita MG, Vore M, Catania VA, Mottino AD.

Drug Metab Dispos. 2012 Jul;40(7):1252-8. doi: 10.1124/dmd.111.044339. Epub 2012 Mar 27.

31.

Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells.

Rigalli JP, Ruiz ML, Perdomo VG, Villanueva SS, Mottino AD, Catania VA.

Toxicology. 2011 Jul 11;285(1-2):18-24. doi: 10.1016/j.tox.2011.03.015. Epub 2011 Apr 1.

PMID:
21459122
32.

Induction of intestinal multidrug resistance-associated protein 2 by glucagon-like Peptide 2 in the rat.

Villanueva SS, Arias A, Ruiz ML, Rigalli JP, Pellegrino JM, Vore M, Catania VA, Mottino AD.

J Pharmacol Exp Ther. 2010 Nov;335(2):332-41. doi: 10.1124/jpet.110.171041. Epub 2010 Aug 18.

PMID:
20719938
33.

Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats.

Ruiz ML, Villanueva SS, Luquita MG, Pellegrino JM, Rigalli JP, Arias A, Sánchez Pozzi EJ, Mottino AD, Catania VA.

Eur J Pharmacol. 2009 Nov 25;623(1-3):103-6. doi: 10.1016/j.ejphar.2009.09.014. Epub 2009 Sep 17.

PMID:
19766108

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