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Items: 1 to 50 of 67

1.

Dopamine gene methylation patterns are associated with obesity markers and carbohydrate intake.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Martinez JA; MENA Project.

Brain Behav. 2018 Aug;8(8):e01017. doi: 10.1002/brb3.1017. Epub 2018 Jul 11.

2.

Interaction between an ADCY3 Genetic Variant and Two Weight-Lowering Diets Affecting Body Fatness and Body Composition Outcomes Depending on Macronutrient Distribution: A Randomized Trial.

Goni L, Riezu-Boj JI, Milagro FI, Corrales FJ, Ortiz L, Cuervo M, Martínez JA.

Nutrients. 2018 Jun 19;10(6). pii: E789. doi: 10.3390/nu10060789.

3.

Circadian gene methylation profiles are associated with obesity, metabolic disturbances and carbohydrate intake.

Ramos-Lopez O, Samblas M, Milagro FI, Riezu-Boj JI, Crujeiras AB, Martinez JA, Project M.

Chronobiol Int. 2018 Jul;35(7):969-981. doi: 10.1080/07420528.2018.1446021. Epub 2018 Mar 26.

PMID:
29580070
4.

Endoplasmic reticulum stress epigenetics is related to adiposity, dyslipidemia, and insulin resistance.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Moreno-Aliaga MJ, Martinez JA; project MENA.

Adipocyte. 2018;7(2):137-142. doi: 10.1080/21623945.2018.1447731. Epub 2018 Mar 23.

PMID:
29570038
5.

Association of low dietary folate intake with lower CAMKK2 gene methylation, adiposity, and insulin resistance in obese subjects.

Ramos-Lopez O, Samblas M, Milagro FI, Zulet MA, Mansego ML, Riezu-Boj JI, Martinez JA.

Nutr Res. 2018 Feb;50:53-62. doi: 10.1016/j.nutres.2017.11.007. Epub 2017 Dec 5.

PMID:
29540272
6.

Association of the Gly482Ser PPARGC1A gene variant with different cholesterol outcomes in response to two energy-restricted diets in subjects with excessive weight.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Goni L, Cuervo M, Martinez JA.

Nutrition. 2018 Mar;47:83-89. doi: 10.1016/j.nut.2017.10.008. Epub 2018 Jan 4.

PMID:
29429541
7.

Differential lipid metabolism outcomes associated with ADRB2 gene polymorphisms in response to two dietary interventions in overweight/obese subjects.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Goni L, Cuervo M, Martinez JA.

Nutr Metab Cardiovasc Dis. 2018 Feb;28(2):165-172. doi: 10.1016/j.numecd.2017.11.006. Epub 2017 Dec 5.

PMID:
29331538
8.

Impact of Consuming Extra-Virgin Olive Oil or Nuts within a Mediterranean Diet on DNA Methylation in Peripheral White Blood Cells within the PREDIMED-Navarra Randomized Controlled Trial: A Role for Dietary Lipids.

Arpón A, Milagro FI, Razquin C, Corella D, Estruch R, Fitó M, Marti A, Martínez-González MA, Ros E, Salas-Salvadó J, Riezu-Boj JI, Martínez JA.

Nutrients. 2017 Dec 23;10(1). pii: E15. doi: 10.3390/nu10010015.

9.

DNA methylation signatures at endoplasmic reticulum stress genes are associated with adiposity and insulin resistance.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Martinez JA; MENA Project.

Mol Genet Metab. 2018 Jan;123(1):50-58. doi: 10.1016/j.ymgme.2017.11.011. Epub 2017 Nov 28.

PMID:
29221916
10.

Methylation changes and pathways affected in preterm birth: a role for SLC6A3 in neurodevelopment.

Arpón A, Milagro FI, Laja A, Segura V, de Pipaón MS, Riezu-Boj JI, Alfredo Martínez J.

Epigenomics. 2018 Jan;10(1):91-103. doi: 10.2217/epi-2017-0082. Epub 2017 Nov 27.

PMID:
29172706
11.

DNA methylation patterns at sweet taste transducing genes are associated with BMI and carbohydrate intake in an adult population.

Ramos-Lopez O, Arpón A, Riezu-Boj JI, Milagro FI, Mansego ML, Martinez JA; MENA project.

Appetite. 2018 Jan 1;120:230-239. doi: 10.1016/j.appet.2017.09.004. Epub 2017 Sep 6.

PMID:
28888730
12.

Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity.

Ramos-Lopez O, Milagro FI, Allayee H, Chmurzynska A, Choi MS, Curi R, De Caterina R, Ferguson LR, Goni L, Kang JX, Kohlmeier M, Marti A, Moreno LA, Pérusse L, Prasad C, Qi L, Reifen R, Riezu-Boj JI, San-Cristobal R, Santos JL, Martínez JA.

J Nutrigenet Nutrigenomics. 2017;10(1-2):43-62. doi: 10.1159/000477729. Epub 2017 Jul 8.

13.

Expansion of Tumor-Infiltrating CD8+ T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy.

Fernandez-Poma SM, Salas-Benito D, Lozano T, Casares N, Riezu-Boj JI, Mancheño U, Elizalde E, Alignani D, Zubeldia N, Otano I, Conde E, Sarobe P, Lasarte JJ, Hervas-Stubbs S.

Cancer Res. 2017 Jul 1;77(13):3672-3684. doi: 10.1158/0008-5472.CAN-17-0236. Epub 2017 May 18.

14.

Gene methylation parallelisms between peripheral blood cells and oral mucosa samples in relation to overweight.

San-Cristobal R, Navas-Carretero S, Milagro FI, Riezu-Boj JI, Guruceaga E, Celis-Morales C, Livingstone KM, Brennan L, Lovegrove JA, Daniel H, Saris WH, Traczyk I, Manios Y, Gibney ER, Gibney MJ, Mathers JC, Martinez JA.

J Physiol Biochem. 2016 Aug;73(3):465-474. doi: 10.1007/s13105-017-0560-6. Epub 2017 Mar 28. Erratum in: J Physiol Biochem. 2017 Oct 5;:.

PMID:
28353150
15.

Adherence to Mediterranean diet is associated with methylation changes in inflammation-related genes in peripheral blood cells.

Arpón A, Riezu-Boj JI, Milagro FI, Marti A, Razquin C, Martínez-González MA, Corella D, Estruch R, Casas R, Fitó M, Ros E, Salas-Salvadó J, Martínez JA.

J Physiol Biochem. 2016 Aug;73(3):445-455. doi: 10.1007/s13105-017-0552-6. Epub 2017 Feb 8. Erratum in: J Physiol Biochem. 2017 Oct 5;:.

PMID:
28181167
16.

Gene expression analysis during acute hepatitis C virus infection associates dendritic cell activation with viral clearance.

Zabaleta A, Riezu-Boj JI, Larrea E, Villanueva L, Lasarte JJ, Guruceaga E, Fisicaro P, Ezzikouri S, Missale G, Ferrari C, Benjelloun S, Prieto J, Sarobe P.

J Med Virol. 2016 May;88(5):843-51. doi: 10.1002/jmv.24399. Epub 2015 Oct 19.

PMID:
26447929
17.

Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation.

Lozano T, Villanueva L, Durántez M, Gorraiz M, Ruiz M, Belsúe V, Riezu-Boj JI, Hervás-Stubbs S, Oyarzábal J, Bandukwala H, Lourenço AR, Coffer PJ, Sarobe P, Prieto J, Casares N, Lasarte JJ.

J Immunol. 2015 Oct 1;195(7):3180-9. doi: 10.4049/jimmunol.1402997. Epub 2015 Aug 31.

18.

Clinical testing of a dendritic cell targeted therapeutic vaccine in patients with chronic hepatitis C virus infection.

Zabaleta A, D'Avola D, Echeverria I, Llopiz D, Silva L, Villanueva L, Riezu-Boj JI, Larrea E, Pereboev A, Lasarte JJ, Rodriguez-Lago I, Iñarrairaegui M, Sangro B, Prieto J, Sarobe P.

Mol Ther Methods Clin Dev. 2015 Mar 11;2:15006. doi: 10.1038/mtm.2015.6. eCollection 2015.

19.

Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12.

Melero I, Quetglas JI, Reboredo M, Dubrot J, Rodriguez-Madoz JR, Mancheño U, Casales E, Riezu-Boj JI, Ruiz-Guillen M, Ochoa MC, Sanmamed MF, Thieblemont N, Smerdou C, Hervas-Stubbs S.

Cancer Res. 2015 Feb 1;75(3):497-507. doi: 10.1158/0008-5472.CAN-13-3356. Epub 2014 Dec 19.

20.

Conventional but not plasmacytoid dendritic cells foster the systemic virus-induced type I IFN response needed for efficient CD8 T cell priming.

Hervas-Stubbs S, Riezu-Boj JI, Mancheño U, Rueda P, Lopez L, Alignani D, Rodríguez-García E, Thieblemont N, Leclerc C.

J Immunol. 2014 Aug 1;193(3):1151-61. doi: 10.4049/jimmunol.1301440. Epub 2014 Jun 27.

21.

Monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model.

Fernández-Suárez D, Celorrio M, Riezu-Boj JI, Ugarte A, Pacheco R, González H, Oyarzabal J, Hillard CJ, Franco R, Aymerich MS.

Neurobiol Aging. 2014 Nov;35(11):2603-2616. doi: 10.1016/j.neurobiolaging.2014.05.021. Epub 2014 May 28.

PMID:
24973119
22.

Characterization of the CD40L/Oncostatin M/Oncostatin M receptor axis as an antiviral and immunostimulatory system disrupted in chronic HCV infection.

Larrea E, Echeverria I, Riezu-Boj JI, Aldabe R, Guembe L, Sola I, Civeira MP, Sarobe P, Prieto J.

J Hepatol. 2014 Mar;60(3):482-9. doi: 10.1016/j.jhep.2013.10.016. Epub 2013 Oct 26.

PMID:
24418171
23.

Dysregulation of interferon regulatory factors impairs the expression of immunostimulatory molecules in hepatitis C virus genotype 1-infected hepatocytes.

Larrea E, Riezu-Boj JI, Aldabe R, Guembe L, Echeverria I, Balasiddaiah A, Gastaminza P, Civeira MP, Sarobe P, Prieto J.

Gut. 2014 Apr;63(4):665-73. doi: 10.1136/gutjnl-2012-304377. Epub 2013 Jun 20.

PMID:
23787026
24.

A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C.

Sangro B, Gomez-Martin C, de la Mata M, Iñarrairaegui M, Garralda E, Barrera P, Riezu-Boj JI, Larrea E, Alfaro C, Sarobe P, Lasarte JJ, Pérez-Gracia JL, Melero I, Prieto J.

J Hepatol. 2013 Jul;59(1):81-8. doi: 10.1016/j.jhep.2013.02.022. Epub 2013 Mar 4.

PMID:
23466307
25.

Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression.

Corrales L, Ajona D, Rafail S, Lasarte JJ, Riezu-Boj JI, Lambris JD, Rouzaut A, Pajares MJ, Montuenga LM, Pio R.

J Immunol. 2012 Nov 1;189(9):4674-83. doi: 10.4049/jimmunol.1201654. Epub 2012 Oct 1.

26.

CD8 T cell priming in the presence of IFN-α renders CTLs with improved responsiveness to homeostatic cytokines and recall antigens: important traits for adoptive T cell therapy.

Hervas-Stubbs S, Mancheño U, Riezu-Boj JI, Larraga A, Ochoa MC, Alignani D, Alfaro C, Morales-Kastresana A, Gonzalez I, Larrea E, Pircher H, Le Bon A, Lopez-Picazo JM, Martín-Algarra S, Prieto J, Melero I.

J Immunol. 2012 Oct 1;189(7):3299-310. Epub 2012 Aug 27.

27.

Cardiotrophin-1 promotes a high survival rate in rabbits with lethal fulminant hepatitis of viral origin.

Tuñon MJ, San Miguel B, Crespo I, Riezu-Boj JI, Larrea E, Alvarez M, González I, Bustos M, González-Gallego J, Prieto J.

J Virol. 2011 Dec;85(24):13124-32. doi: 10.1128/JVI.05725-11. Epub 2011 Oct 5.

28.

Enhanced T cell responses against hepatitis C virus by ex vivo targeting of adenoviral particles to dendritic cells.

Echeverria I, Pereboev A, Silva L, Zabaleta A, Riezu-Boj JI, Bes M, Cubero M, Borras-Cuesta F, Lasarte JJ, Esteban JI, Prieto J, Sarobe P.

Hepatology. 2011 Jul;54(1):28-37. doi: 10.1002/hep.24325. Epub 2011 May 14.

29.

Adjuvant combination and antigen targeting as a strategy to induce polyfunctional and high-avidity T-cell responses against poorly immunogenic tumors.

Aranda F, Llopiz D, Díaz-Valdés N, Riezu-Boj JI, Bezunartea J, Ruiz M, Martínez M, Durantez M, Mansilla C, Prieto J, Lasarte JJ, Borrás-Cuesta F, Sarobe P.

Cancer Res. 2011 May 1;71(9):3214-24. doi: 10.1158/0008-5472.CAN-10-3259. Epub 2011 Mar 14.

30.

Therapeutic effect of a peptide inhibitor of TGF-β on pulmonary fibrosis.

Arribillaga L, Dotor J, Basagoiti M, Riezu-Boj JI, Borrás-Cuesta F, Lasarte JJ, Sarobe P, Cornet ME, Feijoó E.

Cytokine. 2011 Mar;53(3):327-33. doi: 10.1016/j.cyto.2010.11.019. Epub 2010 Dec 23.

PMID:
21185199
31.

Induction of monocyte chemoattractant protein-1 and interleukin-10 by TGFbeta1 in melanoma enhances tumor infiltration and immunosuppression.

Díaz-Valdés N, Basagoiti M, Dotor J, Aranda F, Monreal I, Riezu-Boj JI, Borrás-Cuesta F, Sarobe P, Feijoó E.

Cancer Res. 2011 Feb 1;71(3):812-21. doi: 10.1158/0008-5472.CAN-10-2698. Epub 2010 Dec 15.

32.

Improved dendritic cell-based immunization against hepatitis C virus using peptide inhibitors of interleukin 10.

Díaz-Valdés N, Manterola L, Belsúe V, Riezu-Boj JI, Larrea E, Echeverria I, Llópiz D, López-Sagaseta J, Lerat H, Pawlotsky JM, Prieto J, Lasarte JJ, Borrás-Cuesta F, Sarobe P.

Hepatology. 2011 Jan;53(1):23-31. doi: 10.1002/hep.23980. Epub 2010 Dec 13.

33.

Hepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection.

Riezu-Boj JI, Larrea E, Aldabe R, Guembe L, Casares N, Galeano E, Echeverria I, Sarobe P, Herrero I, Sangro B, Prieto J, Lasarte JJ.

J Hepatol. 2011 Mar;54(3):422-31. doi: 10.1016/j.jhep.2010.07.014. Epub 2010 Sep 26.

34.

Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8(+) T cells.

Hervas-Stubbs S, Riezu-Boj JI, Gonzalez I, Mancheño U, Dubrot J, Azpilicueta A, Gabari I, Palazon A, Aranguren A, Ruiz J, Prieto J, Larrea E, Melero I.

Eur J Immunol. 2010 Dec;40(12):3389-402. doi: 10.1002/eji.201040664.

35.

A peptide inhibitor of FOXP3 impairs regulatory T cell activity and improves vaccine efficacy in mice.

Casares N, Rudilla F, Arribillaga L, Llopiz D, Riezu-Boj JI, Lozano T, López-Sagaseta J, Guembe L, Sarobe P, Prieto J, Borrás-Cuesta F, Lasarte JJ.

J Immunol. 2010 Nov 1;185(9):5150-9. doi: 10.4049/jimmunol.1001114. Epub 2010 Sep 24.

36.

Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis.

Durantez M, Fayolle C, Casares N, Belsue V, Riezu-Boj JI, Sarobe P, Prieto J, Borrás-Cuesta F, Leclerc C, Lasarte JJ.

Vaccine. 2010 Oct 18;28(44):7146-54. doi: 10.1016/j.vaccine.2010.08.070. Epub 2010 Sep 15.

37.

Immunization against hepatitis C virus with a fusion protein containing the extra domain A from fibronectin and the hepatitis C virus NS3 protein.

Mansilla C, Gorraiz M, Martinez M, Casares N, Arribillaga L, Rudilla F, Echeverria I, Riezu-Boj JI, Sarobe P, Borrás-Cuesta F, Prieto J, Lasarte JJ.

J Hepatol. 2009 Sep;51(3):520-7. doi: 10.1016/j.jhep.2009.06.005. Epub 2009 Jun 23.

38.

Monocyte-derived dendritic cells from HCV-infected patients transduced with an adenovirus expressing NS3 are functional when stimulated with the TLR3 ligand poly(I:C).

Echeverría I, Zabaleta A, Silva L, Díaz-Valdés N, Riezu-Boj JI, Lasarte JJ, Borrás-Cuesta F, Civeira MP, Prieto J, Sarobe P.

J Viral Hepat. 2008 Nov;15(11):782-9. doi: 10.1111/j.1365-2893.2008.01020.x. Epub 2008 Jul 10.

PMID:
18637068
39.

In vitro and in vivo down-regulation of regulatory T cell activity with a peptide inhibitor of TGF-beta1.

Gil-Guerrero L, Dotor J, Huibregtse IL, Casares N, López-Vázquez AB, Rudilla F, Riezu-Boj JI, López-Sagaseta J, Hermida J, Van Deventer S, Bezunartea J, Llopiz D, Sarobe P, Prieto J, Borrás-Cuesta F, Lasarte JJ.

J Immunol. 2008 Jul 1;181(1):126-35.

40.

Multipotent Adult Progenitor Cells (MAPC) contribute to hepatocarcinoma neovasculature.

Barajas M, Franchi F, Clavel C, Aranguren XL, Kramer MG, Abizanda G, Merino J, Moreno C, Gárate L, Guitart A, Narvaiza I, Gutiérrez-Perez M, Riezu-Boj JI, Berasain C, Prieto J, Prósper F.

Biochem Biophys Res Commun. 2007 Dec 7;364(1):92-9. Epub 2007 Oct 2.

41.

Vaccination against hepatitis C virus with dendritic cells transduced with an adenovirus encoding NS3 protein.

Zabaleta A, Llopiz D, Arribillaga L, Silva L, Riezu-Boj JI, Lasarte JJ, Borrás-Cuesta F, Prieto J, Sarobe P.

Mol Ther. 2008 Jan;16(1):210-7. Epub 2007 Oct 9.

42.

Identification of peptide inhibitors of transforming growth factor beta 1 using a phage-displayed peptide library.

Dotor J, López-Vázquez AB, Lasarte JJ, Sarobe P, García-Granero M, Riezu-Boj JI, Martínez A, Feijoó E, López-Sagaseta J, Hermida J, Prieto J, Borrás-Cuesta F.

Cytokine. 2007 Aug;39(2):106-15. Epub 2007 Sep 4.

43.

Upregulation of indoleamine 2,3-dioxygenase in hepatitis C virus infection.

Larrea E, Riezu-Boj JI, Gil-Guerrero L, Casares N, Aldabe R, Sarobe P, Civeira MP, Heeney JL, Rollier C, Verstrepen B, Wakita T, Borrás-Cuesta F, Lasarte JJ, Prieto J.

J Virol. 2007 Apr;81(7):3662-6. Epub 2007 Jan 17.

44.

Recombinant adenoviral vectors turn on the type I interferon system without inhibition of transgene expression and viral replication.

Huarte E, Larrea E, Hernández-Alcoceba R, Alfaro C, Murillo O, Arina A, Tirapu I, Azpilicueta A, Hervás-Stubbs S, Bortolanza S, Pérez-Gracia JL, Civeira MP, Prieto J, Riezu-Boj JI, Melero I.

Mol Ther. 2006 Jul;14(1):129-38. Epub 2006 Apr 19.

45.

Hepatitis C virus infection of primary tupaia hepatocytes leads to selection of quasispecies variants, induction of interferon-stimulated genes and NF-kappaB nuclear translocation.

Guitart A, Riezu-Boj JI, Elizalde E, Larrea E, Berasain C, Aldabe R, Civeira MP, Prieto J.

J Gen Virol. 2005 Nov;86(Pt 11):3065-74.

46.

IFN-alpha5 mediates stronger Tyk2-stat-dependent activation and higher expression of 2',5'-oligoadenylate synthetase than IFN-alpha2 in liver cells.

Larrea E, Aldabe R, Riezu-Boj JI, Guitart A, Civeira MP, Prieto J, Baixeras E.

J Interferon Cytokine Res. 2004 Aug;24(8):497-503.

PMID:
15320963
47.

Evolution of naturally occurring 5' non-translated region variants of hepatitis C virus genotype 1b in selectable replicons.

van Leeuwen HC, Reusken CB, Roeten M, Dalebout TJ, Riezu-Boj JI, Ruiz J, Spaan WJ.

J Gen Virol. 2004 Jul;85(Pt 7):1859-66.

PMID:
15218170
48.

The woodchuck interferon-alpha system: Cloning, family description, and biologic activity.

Berraondo P, García-Navarro R, González-Aseguinolaza G, Vales A, Blanco-Urgoiti B, Larrea E, Riezu-Boj JI, Prieto J, Ruiz J.

J Med Virol. 2002 Nov;68(3):424-32.

49.

Specific and general HLA-DR binding motifs: comparison of algorithms.

Borrás-Cuesta F, Golvano J, García-Granero M, Sarobe P, Riezu-Boj J, Huarte E, Lasarte J.

Hum Immunol. 2000 Mar;61(3):266-78.

PMID:
10689116
50.

Immunogenicity of variable regions of hepatitis C virus proteins: selection and modification of peptide epitopes to assess hepatitis C virus genotypes by ELISA.

Rodríguez-López M, Riezu-Boj JI, Ruiz M, Berasain C, Civeira MP, Prieto J, Borrás-Cuesta F.

J Gen Virol. 1999 Mar;80 ( Pt 3):727-38.

PMID:
10092013

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