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Items: 42

1.

Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine.

Mohsen MO, Vogel M, Riether C, Muller J, Salatino S, Ternette N, Gomes AC, Cabral-Miranda G, El-Turabi A, Ruedl C, Kundig TM, Dermime S, Knuth A, Speiser DE, Bachmann MF.

Front Immunol. 2019 May 15;10:1015. doi: 10.3389/fimmu.2019.01015. eCollection 2019.

2.

Correction to: Vaccination with nanoparticles combined with micro-adjuvants protects against cancer.

Mohsen MO, Heath MD, Cabral-Miranda G, Lipp C, Zeltins A, Sande M, Stein JV, Riether C, Roesti E, Zha L, Engeroff P, El-Turabi A, Kundig TM, Vogel M, Skinner MA, Speiser DE, Knuth A, Kramer MF, Bachmann MF.

J Immunother Cancer. 2019 May 23;7(1):137. doi: 10.1186/s40425-019-0616-y.

3.

Vaccination with nanoparticles combined with micro-adjuvants protects against cancer.

Mohsen MO, Heath MD, Cabral-Miranda G, Lipp C, Zeltins A, Sande M, Stein JV, Riether C, Roesti E, Zha L, Engeroff P, El-Turabi A, Kundig TM, Vogel M, Skinner MA, Speiser DE, Knuth A, Kramer MF, Bachmann MF.

J Immunother Cancer. 2019 Apr 26;7(1):114. doi: 10.1186/s40425-019-0587-z. Erratum in: J Immunother Cancer. 2019 May 23;7(1):137.

4.

CD8+ T cells expand stem and progenitor cells in favorable but not adverse risk acute myeloid leukemia.

Radpour R, Riether C, Simillion C, Höpner S, Bruggmann R, Ochsenbein AF.

Leukemia. 2019 Oct;33(10):2379-2392. doi: 10.1038/s41375-019-0441-9. Epub 2019 Mar 15.

PMID:
30877275
5.

Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549.

Tièche CC, Gao Y, Bührer ED, Hobi N, Berezowska SA, Wyler K, Froment L, Weis S, Peng RW, Bruggmann R, Schär P, Amrein MA, Hall SRR, Dorn P, Kocher G, Riether C, Ochsenbein A, Schmid RA, Marti TM.

Neoplasia. 2019 Feb;21(2):185-196. doi: 10.1016/j.neo.2018.09.008. Epub 2018 Dec 27.

6.

T-cell-Secreted TNFα Induces Emergency Myelopoiesis and Myeloid-Derived Suppressor Cell Differentiation in Cancer.

Al Sayed MF, Amrein MA, Bührer ED, Huguenin AL, Radpour R, Riether C, Ochsenbein AF.

Cancer Res. 2019 Jan 15;79(2):346-359. doi: 10.1158/0008-5472.CAN-17-3026. Epub 2018 Nov 2.

PMID:
30389698
7.

mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer.

Liang SQ, Bührer ED, Berezowska S, Marti TM, Xu D, Froment L, Yang H, Hall SRR, Vassella E, Yang Z, Kocher GJ, Amrein MA, Riether C, Ochsenbein AF, Schmid RA, Peng RW.

Oncogene. 2019 Jan;38(5):622-636. doi: 10.1038/s41388-018-0479-6. Epub 2018 Aug 31.

PMID:
30171261
8.

Osteolytic cancer cells induce vascular/axon guidance processes in the bone/bone marrow stroma.

Hensel J, Wetterwald A, Temanni R, Keller I, Riether C, van der Pluijm G, Cecchini MG, Thalmann GN.

Oncotarget. 2018 Jun 22;9(48):28877-28896. doi: 10.18632/oncotarget.25608. eCollection 2018 Jun 22.

9.

Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma.

Xu D, Liang SQ, Yang H, Lüthi U, Riether C, Berezowska S, Marti TM, Hall SRR, Bruggmann R, Kocher GJ, Schmid RA, Peng RW.

Br J Cancer. 2018 Jul;119(1):65-75. doi: 10.1038/s41416-018-0145-3. Epub 2018 Jun 20.

10.

T cell inhibitory mechanisms in a model of aggressive Non-Hodgkin's Lymphoma.

Hilmenyuk T, Ruckstuhl CA, Hayoz M, Berchtold C, Nuoffer JM, Solanki S, Keun HC, Beavis PA, Riether C, Ochsenbein AF.

Oncoimmunology. 2017 Sep 21;7(1):e1365997. doi: 10.1080/2162402X.2017.1365997. eCollection 2017.

11.

CD70 reverse signaling enhances NK cell function and immunosurveillance in CD27-expressing B-cell malignancies.

Al Sayed MF, Ruckstuhl CA, Hilmenyuk T, Claus C, Bourquin JP, Bornhauser BC, Radpour R, Riether C, Ochsenbein AF.

Blood. 2017 Jul 20;130(3):297-309. doi: 10.1182/blood-2016-12-756585. Epub 2017 May 11.

PMID:
28495792
12.

The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34+ Stem/Progenitor Cells.

Murone M, Radpour R, Attinger A, Chessex AV, Huguenin AL, Schürch CM, Banz Y, Sengupta S, Aguet M, Rigotti S, Bachhav Y, Massière F, Ramachandra M, McAllister A, Riether C.

Mol Cancer Ther. 2017 Aug;16(8):1497-1510. doi: 10.1158/1535-7163.MCT-16-0889. Epub 2017 May 3.

13.

CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia.

Riether C, Schürch CM, Bührer ED, Hinterbrandner M, Huguenin AL, Hoepner S, Zlobec I, Pabst T, Radpour R, Ochsenbein AF.

J Exp Med. 2017 Feb;214(2):359-380. doi: 10.1084/jem.20152008. Epub 2016 Dec 28.

14.

TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis.

Zysset D, Weber B, Rihs S, Brasseit J, Freigang S, Riether C, Banz Y, Cerwenka A, Simillion C, Marques-Vidal P, Ochsenbein AF, Saurer L, Mueller C.

Nat Commun. 2016 Oct 20;7:13151. doi: 10.1038/ncomms13151.

15.

Tyrosine kinase inhibitor-induced CD70 expression mediates drug resistance in leukemia stem cells by activating Wnt signaling.

Riether C, Schürch CM, Flury C, Hinterbrandner M, Drück L, Huguenin AL, Baerlocher GM, Radpour R, Ochsenbein AF.

Sci Transl Med. 2015 Jul 29;7(298):298ra119. doi: 10.1126/scitranslmed.aab1740.

PMID:
26223302
16.

IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms.

Mager LF, Riether C, Schürch CM, Banz Y, Wasmer MH, Stuber R, Theocharides AP, Li X, Xia Y, Saito H, Nakae S, Baerlocher GM, Manz MG, McCoy KD, Macpherson AJ, Ochsenbein AF, Beutler B, Krebs P.

J Clin Invest. 2015 Jul 1;125(7):2579-91. doi: 10.1172/JCI77347. Epub 2015 May 26.

17.

CD127+ innate lymphoid cells are dysregulated in treatment naïve acute myeloid leukemia patients at diagnosis.

Trabanelli S, Curti A, Lecciso M, Salomé B, Riether C, Ochsenbein A, Romero P, Jandus C.

Haematologica. 2015 Jul;100(7):e257-60. doi: 10.3324/haematol.2014.119602. Epub 2015 Feb 20. No abstract available.

18.

Blocking programmed cell death 1 in combination with adoptive cytotoxic T-cell transfer eradicates chronic myelogenous leukemia stem cells.

Riether C, Gschwend T, Huguenin AL, Schürch CM, Ochsenbein AF.

Leukemia. 2015 Aug;29(8):1781-5. doi: 10.1038/leu.2015.26. Epub 2015 Feb 4. No abstract available.

19.

Regulation of hematopoietic and leukemic stem cells by the immune system.

Riether C, Schürch CM, Ochsenbein AF.

Cell Death Differ. 2015 Feb;22(2):187-98. doi: 10.1038/cdd.2014.89. Epub 2014 Jul 4. Review.

20.

Cytotoxic CD8+ T cells stimulate hematopoietic progenitors by promoting cytokine release from bone marrow mesenchymal stromal cells.

Schürch CM, Riether C, Ochsenbein AF.

Cell Stem Cell. 2014 Apr 3;14(4):460-72. doi: 10.1016/j.stem.2014.01.002. Epub 2014 Feb 20.

21.

TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance.

Weber B, Schuster S, Zysset D, Rihs S, Dickgreber N, Schürch C, Riether C, Siegrist M, Schneider C, Pawelski H, Gurzeler U, Ziltener P, Genitsch V, Tacchini-Cottier F, Ochsenbein A, Hofstetter W, Kopf M, Kaufmann T, Oxenius A, Reith W, Saurer L, Mueller C.

PLoS Pathog. 2014 Jan;10(1):e1003900. doi: 10.1371/journal.ppat.1003900. Epub 2014 Jan 16.

22.

Dendritic cell-based immunotherapy for myeloid leukemias.

Schürch CM, Riether C, Ochsenbein AF.

Front Immunol. 2013 Dec 31;4:496. doi: 10.3389/fimmu.2013.00496. Review.

23.

Interferons in hematopoiesis and leukemia.

Schürch CM, Riether C, Ochsenbein AF.

Oncoimmunology. 2013 Jun 1;2(6):e24572. Epub 2013 Apr 16.

24.

Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ.

Schürch C, Riether C, Amrein MA, Ochsenbein AF.

J Exp Med. 2013 Mar 11;210(3):605-21. doi: 10.1084/jem.20121229. Epub 2013 Feb 11.

25.

From "magic bullets" to specific cancer immunotherapy.

Riether C, Schürch C, Ochsenbein AF.

Swiss Med Wkly. 2013 Jan 23;143:w13734. doi: 10.4414/smw.2013.13734. eCollection 2013. Review.

26.

Modulating CD27 signaling to treat cancer.

Riether C, Schürch C, Ochsenbein AF.

Oncoimmunology. 2012 Dec 1;1(9):1604-1606.

27.

Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice.

Krstic D, Madhusudan A, Doehner J, Vogel P, Notter T, Imhof C, Manalastas A, Hilfiker M, Pfister S, Schwerdel C, Riether C, Meyer U, Knuesel I.

J Neuroinflammation. 2012 Jul 2;9:151. doi: 10.1186/1742-2094-9-151.

28.

CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.

Claus C, Riether C, Schürch C, Matter MS, Hilmenyuk T, Ochsenbein AF.

Cancer Res. 2012 Jul 15;72(14):3664-76. doi: 10.1158/0008-5472.CAN-11-2791. Epub 2012 May 24.

29.

CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression.

Schürch C, Riether C, Matter MS, Tzankov A, Ochsenbein AF.

J Clin Invest. 2012 Feb;122(2):624-38. doi: 10.1172/JCI45977. Epub 2012 Jan 9.

30.

Neurobehavioural activation during peripheral immunosuppression.

Pacheco-López G, Doenlen R, Krügel U, Arnold M, Wirth T, Riether C, Engler A, Niemi MB, Christians U, Engler H, Schedlowski M.

Int J Neuropsychopharmacol. 2013 Feb;16(1):137-49. doi: 10.1017/S1461145711001799. Epub 2012 Jan 5.

PMID:
22217400
31.

Victims of rape show increased cortisol responses to trauma reminders: a study in individuals with war- and torture-related PTSD.

Gola H, Engler H, Schauer M, Adenauer H, Riether C, Kolassa S, Elbert T, Kolassa IT.

Psychoneuroendocrinology. 2012 Feb;37(2):213-20. doi: 10.1016/j.psyneuen.2011.06.005. Epub 2011 Jul 1.

PMID:
21723669
32.

Acute amygdaloid response to systemic inflammation.

Engler H, Doenlen R, Engler A, Riether C, Prager G, Niemi MB, Pacheco-López G, Krügel U, Schedlowski M.

Brain Behav Immun. 2011 Oct;25(7):1384-92. doi: 10.1016/j.bbi.2011.04.005. Epub 2011 Apr 18.

PMID:
21521653
33.

Electrical activity in rat cortico-limbic structures after single or repeated administration of lipopolysaccharide or staphylococcal enterotoxin B.

Doenlen R, Krügel U, Wirth T, Riether C, Engler A, Prager G, Engler H, Schedlowski M, Pacheco-López G.

Proc Biol Sci. 2011 Jun 22;278(1713):1864-72. doi: 10.1098/rspb.2010.2040. Epub 2010 Nov 24.

34.

Attenuation of the cytotoxic T lymphocyte response to lymphocytic choriomeningitis virus in mice subjected to chronic social stress.

Sommershof A, Basler M, Riether C, Engler H, Groettrup M.

Brain Behav Immun. 2011 Feb;25(2):340-8. doi: 10.1016/j.bbi.2010.10.016. Epub 2010 Oct 23.

PMID:
20974245
35.

Stimulation of β₂-adrenergic receptors inhibits calcineurin activity in CD4(+) T cells via PKA-AKAP interaction.

Riether C, Kavelaars A, Wirth T, Pacheco-López G, Doenlen R, Willemen H, Heijnen CJ, Schedlowski M, Engler H.

Brain Behav Immun. 2011 Jan;25(1):59-66. doi: 10.1016/j.bbi.2010.07.248. Epub 2010 Jul 30.

PMID:
20674738
36.

Chemical destruction of brain noradrenergic neurons affects splenic cytokine production.

Engler H, Doenlen R, Riether C, Engler A, Besedovsky HO, Del Rey A, Pacheco-López G, Schedlowski M.

J Neuroimmunol. 2010 Feb 26;219(1-2):75-80. doi: 10.1016/j.jneuroim.2009.12.001. Epub 2010 Jan 19.

PMID:
20031236
37.

No retrieval-induced forgetting under stress.

Koessler S, Engler H, Riether C, Kissler J.

Psychol Sci. 2009 Nov;20(11):1356-63. doi: 10.1111/j.1467-9280.2009.02450.x. Epub 2009 Oct 8.

PMID:
19818045
38.

Time-dependent alterations of peripheral immune parameters after nigrostriatal dopamine depletion in a rat model of Parkinson's disease.

Engler H, Doenlen R, Riether C, Engler A, Niemi MB, Besedovsky HO, del Rey A, Pacheco-López G, Feldon J, Schedlowski M.

Brain Behav Immun. 2009 May;23(4):518-26. doi: 10.1016/j.bbi.2009.01.018. Epub 2009 Feb 7.

PMID:
19486644
39.

Calcineurin inhibition in splenocytes induced by pavlovian conditioning.

Pacheco-López G, Riether C, Doenlen R, Engler H, Niemi MB, Engler A, Kavelaars A, Heijnen CJ, Schedlowski M.

FASEB J. 2009 Apr;23(4):1161-7. doi: 10.1096/fj.08-115683. Epub 2008 Dec 22.

PMID:
19103649
40.

No PTSD-related differences in diurnal cortisol profiles of genocide survivors.

Eckart C, Engler H, Riether C, Kolassa S, Elbert T, Kolassa IT.

Psychoneuroendocrinology. 2009 May;34(4):523-31. doi: 10.1016/j.psyneuen.2008.10.012. Epub 2008 Dec 2.

PMID:
19054622
41.

Behavioural conditioning of immune functions: how the central nervous system controls peripheral immune responses by evoking associative learning processes.

Riether C, Doenlen R, Pacheco-López G, Niemi MB, Engler A, Engler H, Schedlowski M.

Rev Neurosci. 2008;19(1):1-17. Review.

PMID:
18561817
42.

Weakened [corrected] taste-LPS association during endotoxin tolerance.

Pacheco-Lopez G, Niemi MB, Engler H, Engler A, Riether C, Doenlen R, Espinosa E, Oberbeck R, Schedlowski M.

Physiol Behav. 2008 Jan 28;93(1-2):261-6. Epub 2007 Sep 5. Erratum in: Physiol Behav. 2008 Mar 18;93(4-5):1087.

PMID:
17920645

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