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Items: 26

1.

Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases.

Riester D, Hildmann C, Haus P, Galetovic A, Schober A, Schwienhorst A, Meyer-Almes FJ.

Bioorg Med Chem Lett. 2009 Jul 1;19(13):3651-6. doi: 10.1016/j.bmcl.2009.04.102. Epub 2009 May 3.

PMID:
19457659
2.

Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay.

Wegener D, Hildmann C, Riester D, Schober A, Meyer-Almes FJ, Deubzer HE, Oehme I, Witt O, Lang S, Jaensch M, Makarov V, Lange C, Busse B, Schwienhorst A.

Biochem J. 2008 Jul 1;413(1):143-50. doi: 10.1042/BJ20080536.

PMID:
18384290
3.

Anti-neuroblastoma activity of Helminthosporium carbonum (HC)-toxin is superior to that of other differentiating compounds in vitro.

Deubzer HE, Ehemann V, Kulozik AE, Westermann F, Savelyeva L, Kopp-Schneider A, Riester D, Schwab M, Witt O.

Cancer Lett. 2008 Jun 8;264(1):21-8. doi: 10.1016/j.canlet.2008.01.002. Epub 2008 Feb 8.

PMID:
18262346
4.

Structure of a novel thrombin inhibitor with an uncharged D-amino acid as P1 residue.

Friedrich R, Riester D, Göttig P, Thürk M, Schwienhorst A, Bode W.

Eur J Med Chem. 2008 Jun;43(6):1330-5. Epub 2007 Sep 9.

PMID:
17950494
5.

Inhibitor-mediated stabilization of the conformational structure of a histone deacetylase-like amidohydrolase.

Kern S, Riester D, Hildmann C, Schwienhorst A, Meyer-Almes FJ.

FEBS J. 2007 Jul;274(14):3578-3588. doi: 10.1111/j.1742-4658.2007.05887.x.

6.

Factors affecting the substrate specificity of histone deacetylases.

Riester D, Hildmann C, Grünewald S, Beckers T, Schwienhorst A.

Biochem Biophys Res Commun. 2007 Jun 1;357(2):439-45. Epub 2007 Apr 3.

PMID:
17428445
7.

Complex structure of a bacterial class 2 histone deacetylase homologue with a trifluoromethylketone inhibitor.

Nielsen TK, Hildmann C, Riester D, Wegener D, Schwienhorst A, Ficner R.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt 4):270-3. Epub 2007 Mar 23.

8.

Histone deacetylases--an important class of cellular regulators with a variety of functions.

Hildmann C, Riester D, Schwienhorst A.

Appl Microbiol Biotechnol. 2007 Jun;75(3):487-97. Epub 2007 Mar 22. Review.

PMID:
17377789
9.

Histone deacetylase inhibitors--turning epigenic mechanisms of gene regulation into tools of therapeutic intervention in malignant and other diseases.

Riester D, Hildmann C, Schwienhorst A.

Appl Microbiol Biotechnol. 2007 Jun;75(3):499-514. Epub 2007 Mar 22. Review.

PMID:
17377788
10.

Histone deacetylase inhibitor assay based on fluorescence resonance energy transfer.

Riester D, Hildmann C, Schwienhorst A, Meyer-Almes FJ.

Anal Biochem. 2007 Mar 1;362(1):136-41. Epub 2007 Jan 4.

PMID:
17250798
11.

An active site tyrosine residue is essential for amidohydrolase but not for esterase activity of a class 2 histone deacetylase-like bacterial enzyme.

Moreth K, Riester D, Hildmann C, Hempel R, Wegener D, Schober A, Schwienhorst A.

Biochem J. 2007 Feb 1;401(3):659-65.

12.

Spatially encoded single-bead Biginelli synthesis in a microstructured silicon array.

Gross GA, Mayer G, Albert J, Riester D, Osterodt J, Wurziger H, Schober A.

Angew Chem Int Ed Engl. 2006 May 5;45(19):3102-6. No abstract available.

PMID:
16572500
13.

Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases.

Hildmann C, Wegener D, Riester D, Hempel R, Schober A, Merana J, Giurato L, Guccione S, Nielsen TK, Ficner R, Schwienhorst A.

J Biotechnol. 2006 Jun 25;124(1):258-70. Epub 2006 Mar 29.

PMID:
16567013
14.

Thrombin inhibitors identified by computer-assisted multiparameter design.

Riester D, Wirsching F, Salinas G, Keller M, Gebinoga M, Kamphausen S, Merkwirth C, Goetz R, Wiesenfeldt M, Stürzebecher J, Bode W, Friedrich R, Thürk M, Schwienhorst A.

Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8597-602. Epub 2005 Jun 3.

15.

Members of the histone deacetylase superfamily differ in substrate specificity towards small synthetic substrates.

Riester D, Wegener D, Hildmann C, Schwienhorst A.

Biochem Biophys Res Commun. 2004 Nov 19;324(3):1116-23.

PMID:
15485670
16.

A new amidohydrolase from Bordetella or Alcaligenes strain FB188 with similarities to histone deacetylases.

Hildmann C, Ninkovic M, Dietrich R, Wegener D, Riester D, Zimmermann T, Birch OM, Bernegger C, Loidl P, Schwienhorst A.

J Bacteriol. 2004 Apr;186(8):2328-39.

17.

Directed evolution towards protease-resistant hirudin variants.

Wirsching F, Keller M, Hildmann C, Riester D, Schwienhorst A.

Mol Genet Metab. 2003 Dec;80(4):451-62.

PMID:
14654359
18.

Improved fluorogenic histone deacetylase assay for high-throughput-screening applications.

Wegener D, Hildmann C, Riester D, Schwienhorst A.

Anal Biochem. 2003 Oct 15;321(2):202-8.

PMID:
14511685
19.

Genetic algorithm for the design of molecules with desired properties.

Kamphausen S, Höltge N, Wirsching F, Morys-Wortmann C, Riester D, Goetz R, Thürk M, Schwienhorst A.

J Comput Aided Mol Des. 2002 Aug-Sep;16(8-9):551-67.

PMID:
12602950
20.

A fluorogenic histone deacetylase assay well suited for high-throughput activity screening.

Wegener D, Wirsching F, Riester D, Schwienhorst A.

Chem Biol. 2003 Jan;10(1):61-8.

PMID:
12573699
21.

Fluorogenic assay for penicillin G acylase activity.

Ninkovic M, Riester D, Wirsching F, Dietrich R, Schwienhorst A.

Anal Biochem. 2001 May 15;292(2):228-33.

PMID:
11355855
22.

Racemization of amino acids in solid-phase peptide synthesis investigated by capillary electrophoresis.

Riester D, Wiesmüller KH, Stoll D, Kuhn R.

Anal Chem. 1996 Jul 15;68(14):2361-5.

PMID:
8686928
23.

Evaluation of an optically active crown ether for the chiral separation of di- and tripeptides.

Kuhn R, Riester D, Fleckenstein B, Wiesmüller KH.

J Chromatogr A. 1995 Nov 17;716(1-2):371-9.

PMID:
8574392
24.

Surveillance for HIV antibody and antigen in trauma patients.

Orr MD, Hoos A, Riester DE, Gilcher RO, Meltz ML.

J Emerg Med. 1991;9 Suppl 1:1-3.

PMID:
1955674
25.

Complement activation in shed blood: release of C3a and C5a. Implications for autologous transfusion.

Orr MD, Riester DE, Hultman J.

J Cardiothorac Anesth. 1989 Oct;3(5 Suppl 1):85.

PMID:
2521018
26.

HIV-1 infection in patients with penetrating trauma in San Antonio, Tex.

Orr MD, Hoos A, Riester DE, Meltz ML, Gilcher RO.

JAMA. 1989 Sep 22-29;262(12):1629. No abstract available.

PMID:
2769914

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