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Understanding the causes of mortality post-transplantation - there is more than meets the eye.

Riella LV.

J Bras Nefrol. 2018 Jun 25. pii: S0101-28002018005018103. doi: 10.1590/2175-8239-jbn-2018-0002-0003. [Epub ahead of print] Portuguese, English. No abstract available.


Risk factors associated with post-kidney transplant malignancies: an article from the Cancer-Kidney International Network.

Sprangers B, Nair V, Launay-Vacher V, Riella LV, Jhaveri KD.

Clin Kidney J. 2018 Jun;11(3):315-329. doi: 10.1093/ckj/sfx122. Epub 2017 Oct 27.


Eponychial lesions following bilateral upper extremity vascular composite allotransplantation: a case report.

Fallahian F, Molway D, Jadeja S, Clark R, Marty FM, Riella LV, Chandraker A, Talbot SG.

Case Reports Plast Surg Hand Surg. 2018 Feb 2;5(1):14-17. doi: 10.1080/23320885.2018.1431047. eCollection 2018.


Novel Role of Calcineurin Inhibitors in Curbing T Cells' Sweet Tooth.

Riella LV, Alegre ML.

Am J Transplant. 2018 Jan;18(1):3. doi: 10.1111/ajt.14606. No abstract available.


Human regulatory T cells undergo self-inflicted damage via granzyme pathways upon activation.

Sula Karreci E, Eskandari SK, Dotiwala F, Routray SK, Kurdi AT, Assaker JP, Luckyanchykov P, Mihali AB, Maarouf O, Borges TJ, Alkhudhayri A, Patel KR, Radwan A, Ghobrial I, McGrath M, Chandraker A, Riella LV, Elyaman W, Abdi R, Lieberman J, Azzi J.

JCI Insight. 2017 Nov 2;2(21). pii: 91599. doi: 10.1172/jci.insight.91599. [Epub ahead of print]


Belatacept in kidney transplantation - past and future perspectives.

Siddiqui Z, Tedesco-Silva H, Riella LV.

J Bras Nefrol. 2017 Apr-Jun;39(2):205-212. doi: 10.5935/0101-2800.20170035. English, Portuguese.


The outstanding questions in transplantation: It's about time….

Azzi J, Raimondi G, Mas V, Riella LV, Elfadawy N, Safa K, Wojciechowski D, Kanak M, Nog R, Maltzman JS, Ford ML, Pober JS, Luo XR, Rothstein D, Miller ML, Matthews D, Burlingham W, Levings M, Heeger P, Higdon L, Gill J, Gill RG, Alegre ML.

Am J Transplant. 2018 Jan;18(1):271-272. doi: 10.1111/ajt.14450. Epub 2017 Sep 2. No abstract available.


Longitudinal immunological characterization of the first presensitized recipient of a face transplant.

Win TS, Murakami N, Borges TJ, Chandraker A, Murphy G, Lian C, Barrera V, Ho Sui S, Schoenfeld D, Teague J, Bueno E, Tullius SG, Pomahac B, Clark RA, Riella LV.

JCI Insight. 2017 Jul 6;2(13). pii: 93894. doi: 10.1172/jci.insight.93894. [Epub ahead of print]


Chronic Allograft Injury: An Overview of Pathogenesis and Treatment Strategies.

Madariaga HM, Riella LV.

Contrib Nephrol. 2017;190:168-180. doi: 10.1159/000468963. Epub 2017 May 23. Review.


Impact of environmental factors on alloimmunity and transplant fate.

Riella LV, Bagley J, Iacomini J, Alegre ML.

J Clin Invest. 2017 Jun 30;127(7):2482-2491. doi: 10.1172/JCI90596. Epub 2017 May 8. Review.


Acellular Hypothermic Extracorporeal Perfusion Extends Allowable Ischemia Time in a Porcine Whole Limb Replantation Model.

Kueckelhaus M, Dermietzel A, Alhefzi M, Aycart MA, Fischer S, Krezdorn N, Wo L, Maarouf OH, Riella LV, Abdi R, Bueno EM, Pomahac B.

Plast Reconstr Surg. 2017 Apr;139(4):922e-932e. doi: 10.1097/PRS.0000000000003208.


Renal complications of immune checkpoint blockade.

Murakami N, Motwani S, Riella LV.

Curr Probl Cancer. 2017 Mar - Apr;41(2):100-110. doi: 10.1016/j.currproblcancer.2016.12.004. Epub 2016 Dec 19. Review.


A Decision-Making Algorithm for Initiation and Discontinuation of RRT in Severe AKI.

Mendu ML, Ciociolo GR Jr, McLaughlin SR, Graham DA, Ghazinouri R, Parmar S, Grossier A, Rosen R, Laskowski KR, Riella LV, Robinson ES, Charytan DM, Bonventre JV, Greenberg JO, Waikar SS.

Clin J Am Soc Nephrol. 2017 Feb 7;12(2):228-236. doi: 10.2215/CJN.07170716. Epub 2017 Jan 24.


Acute myeloid leukemia after kidney transplantation: a case report and literature review.

Cardarelli F, Bijol V, Chandraker A, Varga C, Riella LV.

J Bras Nefrol. 2016 Dec;38(4):455-461. doi: 10.5935/0101-2800.20160072. Review. Portuguese, English.


Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice.

Sula Karreci E, Fan H, Uehara M, Mihali AB, Singh PK, Kurdi AT, Solhjou Z, Riella LV, Ghobrial I, Laragione T, Routray S, Assaker JP, Wang R, Sukenick G, Shi L, Barrat FJ, Nathan CF, Lin G, Azzi J.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8425-E8432. doi: 10.1073/pnas.1618548114. Epub 2016 Dec 12.


Notch Signaling and Immune Regulation in Alloimmunity.

Murakami N, Maillard I, Riella LV.

Curr Transplant Rep. 2016 Dec;3(4):294-302. doi: 10.1007/s40472-016-0126-5. Epub 2016 Oct 10.


Chronic allograft injury: Mechanisms and potential treatment targets.

Riella LV, Djamali A, Pascual J.

Transplant Rev (Orlando). 2017 Jan;31(1):1-9. doi: 10.1016/j.trre.2016.10.005. Epub 2016 Oct 11. Review.


Immunological Characteristics of a Patient With Belatacept-Resistant Acute Rejection After Face Transplantation.

Krezdorn N, Murakami N, Pomahac B, Riella LV.

Am J Transplant. 2016 Nov;16(11):3305-3307. doi: 10.1111/ajt.13977. Epub 2016 Aug 26. No abstract available.


Inflammation Causes Resistance to Anti-CD20-Mediated B Cell Depletion.

Laws LH, Parker CE, Cherala G, Koguchi Y, Waisman A, Slifka MK, Oberbarnscheidt MH, Obhrai JS, Yeung MY, Riella LV.

Am J Transplant. 2016 Nov;16(11):3139-3149. doi: 10.1111/ajt.13902. Epub 2016 Jul 12.


Targeting the Notch Pathway to Prevent Rejection.

Chung J, Riella LV, Maillard I.

Am J Transplant. 2016 Nov;16(11):3079-3085. doi: 10.1111/ajt.13816. Epub 2016 May 5. Review.


Current status of alloimmunity.

Borges TJ, Murakami N, Riella LV.

Curr Opin Nephrol Hypertens. 2016 Nov;25(6):556-562. Review.


Treg-Centric View of Immunosuppressive Drugs in Transplantation: A Balancing Act.

Camirand G, Riella LV.

Am J Transplant. 2017 Mar;17(3):601-610. doi: 10.1111/ajt.14029. Epub 2016 Oct 3. Review.


Erratum: Severe acute interstitial nephritis after combination immune-checkpoint inhibitor therapy for metastatic melanoma.

Murakami N, Borges TJ, Yamashita M, Riella LV.

Clin Kidney J. 2016 Aug;9(4):649. doi: 10.1093/ckj/sfw058. Epub 2016 Jun 21.


Efficacy and Safety of Direct Acting Antivirals in Kidney Transplant Recipients with Chronic Hepatitis C Virus Infection.

Lin MV, Sise ME, Pavlakis M, Amundsen BM, Chute D, Rutherford AE, Chung RT, Curry MP, Hanifi JM, Gabardi S, Chandraker A, Heher EC, Elias N, Riella LV.

PLoS One. 2016 Jul 14;11(7):e0158431. doi: 10.1371/journal.pone.0158431. eCollection 2016.


Belatacept and Long-Term Outcomes in Kidney Transplantation.

Riella LV, Gabardi S, Azzi J.

N Engl J Med. 2016 Jun 30;374(26):2599-600. doi: 10.1056/NEJMc1602859. No abstract available.


Severe acute interstitial nephritis after combination immune-checkpoint inhibitor therapy for metastatic melanoma.

Murakami N, Borges TJ, Yamashita M, Riella LV.

Clin Kidney J. 2016 Jun;9(3):411-7. doi: 10.1093/ckj/sfw024. Epub 2016 May 4. Erratum in: Clin Kidney J. 2016 Aug;9(4):649.


Coronary artery calcium density for the prediction of mortality in CKD patients: One size does not fit all.

Bittencourt MS, Riella LV.

Atherosclerosis. 2016 Jul;250:180-2. doi: 10.1016/j.atherosclerosis.2016.05.016. Epub 2016 May 7. No abstract available.


Digital Learning in Transplantation.

Riella LV.

Transplantation. 2016 Apr;100(4):701-2. doi: 10.1097/TP.0000000000001174. No abstract available.


Codominant Role of Interferon-γ- and Interleukin-17-Producing T Cells During Rejection in Full Facial Transplant Recipients.

Borges TJ, O'Malley JT, Wo L, Murakami N, Smith B, Azzi J, Tripathi S, Lane JD, Bueno EM, Clark RA, Tullius SG, Chandraker A, Lian CG, Murphy GF, Strom TB, Pomahac B, Najafian N, Riella LV.

Am J Transplant. 2016 Jul;16(7):2158-71. doi: 10.1111/ajt.13705. Epub 2016 Apr 7.


Notch and its ligands in alloimmunity and rejection.

Magee CN, Riella LV.

Curr Opin Organ Transplant. 2016 Feb;21(1):15-21. doi: 10.1097/MOT.0000000000000266. Review.


CD4+ CD28-Negative Cells: Armed and Dangerous.

Murakami N, Riella LV.

Am J Transplant. 2016 Apr;16(4):1045-6. doi: 10.1111/ajt.13646. Epub 2016 Feb 1. No abstract available.


Recombinant PTH therapy for severe hypoparathyroidism after kidney transplantation in pre-transplant parathyroidectomized patients: review of the literature and a case report.

Hod T, Riella LV, Chandraker A.

Clin Transplant. 2015 Nov;29(11):951-7. doi: 10.1111/ctr.12622. Epub 2015 Sep 28. Review.


Testing for High-Risk APOL1 Alleles in Potential Living Kidney Donors.

Riella LV, Sheridan AM.

Am J Kidney Dis. 2015 Sep;66(3):396-401. doi: 10.1053/j.ajkd.2015.04.046. Epub 2015 Jun 3.


Salt Accelerates Allograft Rejection through Serum- and Glucocorticoid-Regulated Kinase-1-Dependent Inhibition of Regulatory T Cells.

Safa K, Ohori S, Borges TJ, Uehara M, Batal I, Shimizu T, Magee CN, Belizaire R, Abdi R, Wu C, Chandraker A, Riella LV.

J Am Soc Nephrol. 2015 Oct;26(10):2341-7. doi: 10.1681/ASN.2014090914. Epub 2015 Apr 1.


Incremental prognostic value of kidney function decline over coronary artery disease for cardiovascular event prediction after coronary computed tomography.

Bittencourt MS, Hulten EA, Ghoshhajra B, Abbara S, Murthy VL, Divakaran S, Nasir K, Gowdak LH, Riella LV, Chiumiento M, Hoffmann U, Di Carli MF, Blankstein R.

Kidney Int. 2015 Jul;88(1):152-9. doi: 10.1038/ki.2014.426. Epub 2015 Jan 28.


Acute rejection in vascularized composite allotransplantation.

Fischer S, Lian CG, Kueckelhaus M, Strom TB, Edelman ER, Clark RA, Murphy GF, Chandraker AK, Riella LV, Tullius SG, Pomahac B.

Curr Opin Organ Transplant. 2014 Dec;19(6):531-44. doi: 10.1097/MOT.0000000000000140. Review.


Counseling potential donors to the risk of ESRD after kidney donation: glass half-full or half-empty?

Allegretti AS, Yeung MY, Riella LV.

Am J Transplant. 2014 Oct;14(10):2434-5. doi: 10.1111/ajt.12861. Epub 2014 Aug 28. No abstract available.


Risk of metabolic complications in kidney transplantation after conversion to mTOR inhibitor: a systematic review and meta-analysis.

Murakami N, Riella LV, Funakoshi T.

Am J Transplant. 2014 Oct;14(10):2317-27. doi: 10.1111/ajt.12852. Epub 2014 Aug 21. Review.


Immunophenotyping and efficacy of low dose ATG in non-sensitized kidney recipients undergoing early steroid withdrawal: a randomized pilot study.

Grafals M, Smith B, Murakami N, Trabucco A, Hamill K, Marangos E, Gilligan H, Pomfret EA, Pomposelli JJ, Simpson MA, Azzi J, Najafian N, Riella LV.

PLoS One. 2014 Aug 11;9(8):e104408. doi: 10.1371/journal.pone.0104408. eCollection 2014.


Co-inhibitory pathways and their importance in immune regulation.

Murakami N, Riella LV.

Transplantation. 2014 Jul 15;98(1):3-14. doi: 10.1097/TP.0000000000000169. Review.


Long-term outcomes of kidney transplantation across a positive complement-dependent cytotoxicity crossmatch.

Riella LV, Safa K, Yagan J, Lee B, Azzi J, Najafian N, Abdi R, Milford E, Mah H, Gabardi S, Malek S, Tullius SG, Magee C, Chandraker A.

Transplantation. 2014 Jun 27;97(12):1247-52. doi: 10.1097/01.TP.0000442782.98131.7c.


Beyond calcineurin inhibitors: emerging agents in kidney transplantation.

Safa K, Riella LV, Chandraker A.

Curr Opin Nephrol Hypertens. 2013 Nov;22(6):689-97. doi: 10.1097/MNH.0b013e328365b3e6. Review.


T-cell co-stimulatory blockade in transplantation: two steps forward one step back!

Riella LV, Sayegh MH.

Expert Opin Biol Ther. 2013 Nov;13(11):1557-68. doi: 10.1517/14712598.2013.845661. Epub 2013 Oct 1. Review.


Serine protease inhibitor 6 plays a critical role in protecting murine granzyme B-producing regulatory T cells.

Azzi J, Skartsis N, Mounayar M, Magee CN, Batal I, Ting C, Moore R, Riella LV, Ohori S, Abdoli R, Smith B, Fiorina P, Heathcote D, Bakhos T, Ashton-Rickardt PG, Abdi R.

J Immunol. 2013 Sep 1;191(5):2319-27. doi: 10.4049/jimmunol.1300851. Epub 2013 Aug 2.


B7h (ICOS-L) maintains tolerance at the fetomaternal interface.

Riella LV, Dada S, Chabtini L, Smith B, Huang L, Dakle P, Mfarrej B, D'Addio F, Adams LT, Kochupurakkal N, Vergani A, Fiorina P, Mellor AL, Sharpe AH, Yagita H, Guleria I.

Am J Pathol. 2013 Jun;182(6):2204-13. doi: 10.1016/j.ajpath.2013.02.014. Epub 2013 Apr 8.


Jagged2-signaling promotes IL-6-dependent transplant rejection.

Riella LV, Yang J, Chock S, Safa K, Magee CN, Vanguri V, Elyaman W, Lahoud Y, Yagita H, Abdi R, Najafian N, Medina-Pestana JO, Chandraker A.

Eur J Immunol. 2013 Jun;43(6):1449-58. doi: 10.1002/eji.201243151. Epub 2013 May 2.


Fever, dysuria and elevated serum creatinine in a kidney transplant recipient.

Batal I, Bijol V, Riella LV, Rennke HG.

Am J Transplant. 2013 Mar;13(3):817-8. doi: 10.1111/ajt.12012. No abstract available.


Role of the PD-1 pathway in the immune response.

Riella LV, Paterson AM, Sharpe AH, Chandraker A.

Am J Transplant. 2012 Oct;12(10):2575-87. doi: 10.1111/j.1600-6143.2012.04224.x. Epub 2012 Aug 17. Review.


Stem cell therapy in kidney transplantation.

Riella LV, Chandraker A.

JAMA. 2012 Jul 11;308(2):130; author reply 130-1. doi: 10.1001/jama.2012.6370. No abstract available.


Dyslipidemia and its therapeutic challenges in renal transplantation.

Riella LV, Gabardi S, Chandraker A.

Am J Transplant. 2012 Aug;12(8):1975-82. doi: 10.1111/j.1600-6143.2012.04084.x. Epub 2012 May 11. Review.

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