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Items: 5


Cancer Precision Medicine: Why More Is More and DNA Is Not Enough.

Schütte M, Ogilvie LA, Rieke DT, Lange BMH, Yaspo ML, Lehrach H.

Public Health Genomics. 2017;20(2):70-80. doi: 10.1159/000477157. Epub 2017 Jun 9. Review.


CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer.

Griffith M, Spies NC, Krysiak K, McMichael JF, Coffman AC, Danos AM, Ainscough BJ, Ramirez CA, Rieke DT, Kujan L, Barnell EK, Wagner AH, Skidmore ZL, Wollam A, Liu CJ, Jones MR, Bilski RL, Lesurf R, Feng YY, Shah NM, Bonakdar M, Trani L, Matlock M, Ramu A, Campbell KM, Spies GC, Graubert AP, Gangavarapu K, Eldred JM, Larson DE, Walker JR, Good BM, Wu C, Su AI, Dienstmann R, Margolin AA, Tamborero D, Lopez-Bigas N, Jones SJ, Bose R, Spencer DH, Wartman LD, Wilson RK, Mardis ER, Griffith OL.

Nat Genet. 2017 Jan 31;49(2):170-174. doi: 10.1038/ng.3774. No abstract available.


Targeted Therapy of Head and Neck Cancer.

Rieke DT, Klinghammer K, Keilholz U.

Oncol Res Treat. 2016;39(12):780-786. Epub 2016 Nov 22. Review.


Systemic Treatment in HPV-Induced Recurrent or Metastatic HNSCC.

Rieke DT, Keilholz U.

Recent Results Cancer Res. 2017;206:149-160. Review.


Methylation of RAD51B, XRCC3 and other homologous recombination genes is associated with expression of immune checkpoints and an inflammatory signature in squamous cell carcinoma of the head and neck, lung and cervix.

Rieke DT, Ochsenreither S, Klinghammer K, Seiwert TY, Klauschen F, Tinhofer I, Keilholz U.

Oncotarget. 2016 Nov 15;7(46):75379-75393. doi: 10.18632/oncotarget.12211.

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