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Effect of Rifampicin on the Pharmacokinetics of a Single Dose of Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Malignancy.

Zhang W, McIntyre C, Forbes H, Gaafar R, Kohail H, Beck JT, Plestina S, Bertran E, Riehl T.

Clin Pharmacol Drug Dev. 2018 Dec 20. doi: 10.1002/cpdd.643. [Epub ahead of print]


BRAF Inhibition in BRAFV600-Mutant Gliomas: Results From the VE-BASKET Study.

Kaley T, Touat M, Subbiah V, Hollebecque A, Rodon J, Lockhart AC, Keedy V, Bielle F, Hofheinz RD, Joly F, Blay JY, Chau I, Puzanov I, Raje NS, Wolf J, DeAngelis LM, Makrutzki M, Riehl T, Pitcher B, Baselga J, Hyman DM.

J Clin Oncol. 2018 Oct 23:JCO2018789990. doi: 10.1200/JCO.2018.78.9990. [Epub ahead of print]


Safety and efficacy of vismodegib in relapsed/refractory acute myeloid leukaemia: results of a phase Ib trial.

Bixby D, Noppeney R, Lin TL, Cortes J, Krauter J, Yee K, Medeiros BC, Krämer A, Assouline S, Fiedler W, Dimier N, Simmons BP, Riehl T, Colburn D.

Br J Haematol. 2019 May;185(3):595-598. doi: 10.1111/bjh.15571. Epub 2018 Sep 11. No abstract available.


Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab.

Gandara DR, Paul SM, Kowanetz M, Schleifman E, Zou W, Li Y, Rittmeyer A, Fehrenbacher L, Otto G, Malboeuf C, Lieber DS, Lipson D, Silterra J, Amler L, Riehl T, Cummings CA, Hegde PS, Sandler A, Ballinger M, Fabrizio D, Mok T, Shames DS.

Nat Med. 2018 Sep;24(9):1441-1448. doi: 10.1038/s41591-018-0134-3. Epub 2018 Aug 6.


TRPV4 Channel Signaling in Macrophages Promotes Gastrointestinal Motility via Direct Effects on Smooth Muscle Cells.

Luo J, Qian A, Oetjen LK, Yu W, Yang P, Feng J, Xie Z, Liu S, Yin S, Dryn D, Cheng J, Riehl TE, Zholos AV, Stenson WF, Kim BS, Hu H.

Immunity. 2018 Jul 17;49(1):107-119.e4. doi: 10.1016/j.immuni.2018.04.021. Epub 2018 Jun 26.


Lactobacillus rhamnosus GG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal stem cells.

Riehl TE, Alvarado D, Ee X, Zuckerman A, Foster L, Kapoor V, Thotala D, Ciorba MA, Stenson WF.

Gut. 2019 Jun;68(6):1003-1013. doi: 10.1136/gutjnl-2018-316226. Epub 2018 Jun 22.


Vemurafenib for BRAF V600-Mutant Erdheim-Chester Disease and Langerhans Cell Histiocytosis: Analysis of Data From the Histology-Independent, Phase 2, Open-label VE-BASKET Study.

Diamond EL, Subbiah V, Lockhart AC, Blay JY, Puzanov I, Chau I, Raje NS, Wolf J, Erinjeri JP, Torrisi J, Lacouture M, Elez E, Martínez-Valle F, Durham B, Arcila ME, Ulaner G, Abdel-Wahab O, Pitcher B, Makrutzki M, Riehl T, Baselga J, Hyman DM.

JAMA Oncol. 2018 Mar 1;4(3):384-388. doi: 10.1001/jamaoncol.2017.5029.


BRAFV600 mutations in solid tumors, other than metastatic melanoma and papillary thyroid cancer, or multiple myeloma: a screening study.

Cohn AL, Day BM, Abhyankar S, McKenna E, Riehl T, Puzanov I.

Onco Targets Ther. 2017 Feb 17;10:965-971. doi: 10.2147/OTT.S120440. eCollection 2017.


Vemurafenib in patients with BRAF(V600E)-positive metastatic or unresectable papillary thyroid cancer refractory to radioactive iodine: a non-randomised, multicentre, open-label, phase 2 trial.

Brose MS, Cabanillas ME, Cohen EE, Wirth LJ, Riehl T, Yue H, Sherman SI, Sherman EJ.

Lancet Oncol. 2016 Sep;17(9):1272-82. doi: 10.1016/S1470-2045(16)30166-8. Epub 2016 Jul 23.


CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice.

Riehl TE, Santhanam S, Foster L, Ciorba M, Stenson WF.

Am J Physiol Gastrointest Liver Physiol. 2015 Dec 1;309(11):G874-87. doi: 10.1152/ajpgi.00123.2015. Epub 2015 Oct 1.


Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis.

Hannan TJ, Roberts PL, Riehl TE, van der Post S, Binkley JM, Schwartz DJ, Miyoshi H, Mack M, Schwendener RA, Hooton TM, Stappenbeck TS, Hansson GC, Stenson WF, Colonna M, Stapleton AE, Hultgren SJ.

EBioMedicine. 2014 Oct 24;1(1):46-57. doi: 10.1016/j.ebiom.2014.10.011. eCollection 2014 Nov.


Multiple origins of subsociality in crab spiders (Thomisidae).

Ruch J, Riehl T, May-Collado LJ, Agnarsson I.

Mol Phylogenet Evol. 2015 Jan;82 Pt A:330-40. doi: 10.1016/j.ympev.2014.10.015. Epub 2014 Oct 28.


Re-description of Xysticus bimaculatus L. Koch, 1867 (Araneae, Thomisidae) and characterization of its subsocial lifestyle.

Ruch J, Riehl T, Michalik P.

Zookeys. 2014 Jul 21;(427):1-19. doi: 10.3897/zookeys.427.7450. eCollection 2014.


Genetic and morphological divergences in the cosmopolitan deep-sea amphipod Eurythenes gryllus reveal a diverse abyss and a bipolar species.

Havermans C, Sonet G, d'Udekem d'Acoz C, Nagy ZT, Martin P, Brix S, Riehl T, Agrawal S, Held C.

PLoS One. 2013 Sep 25;8(9):e74218. doi: 10.1371/journal.pone.0074218. eCollection 2013.


The hyaluronic acid receptor CD44 coordinates normal and metaplastic gastric epithelial progenitor cell proliferation.

Khurana SS, Riehl TE, Moore BD, Fassan M, Rugge M, Romero-Gallo J, Noto J, Peek RM Jr, Stenson WF, Mills JC.

J Biol Chem. 2013 May 31;288(22):16085-97. doi: 10.1074/jbc.M112.445551. Epub 2013 Apr 15.


CD36-dependent signaling mediates fatty acid-induced gut release of secretin and cholecystokinin.

Sundaresan S, Shahid R, Riehl TE, Chandra R, Nassir F, Stenson WF, Liddle RA, Abumrad NA.

FASEB J. 2013 Mar;27(3):1191-202. doi: 10.1096/fj.12-217703. Epub 2012 Dec 11.


Conquered from the deep sea? A new deep-sea isopod species from the Antarctic shelf shows pattern of recent colonization.

Riehl T, Kaiser S.

PLoS One. 2012;7(11):e49354. doi: 10.1371/journal.pone.0049354. Epub 2012 Nov 7.


Reliability of quantitative EEG (qEEG) measures and LORETA current source density at 30 days.

Cannon RL, Baldwin DR, Shaw TL, Diloreto DJ, Phillips SM, Scruggs AM, Riehl TC.

Neurosci Lett. 2012 Jun 14;518(1):27-31. doi: 10.1016/j.neulet.2012.04.035. Epub 2012 May 3.


Hyaluronic acid regulates normal intestinal and colonic growth in mice.

Riehl TE, Ee X, Stenson WF.

Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1;303(3):G377-88. doi: 10.1152/ajpgi.00034.2012. Epub 2012 May 3.


Hyaluronic acid is radioprotective in the intestine through a TLR4 and COX-2-mediated mechanism.

Riehl TE, Foster L, Stenson WF.

Am J Physiol Gastrointest Liver Physiol. 2012 Feb 1;302(3):G309-16. doi: 10.1152/ajpgi.00248.2011. Epub 2011 Oct 28.


Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner.

Ciorba MA, Riehl TE, Rao MS, Moon C, Ee X, Nava GM, Walker MR, Marinshaw JM, Stappenbeck TS, Stenson WF.

Gut. 2012 Jun;61(6):829-38. doi: 10.1136/gutjnl-2011-300367. Epub 2011 Oct 24.


Serum analysis of tryptophan catabolism pathway: correlation with Crohn's disease activity.

Gupta NK, Thaker AI, Kanuri N, Riehl TE, Rowley CW, Stenson WF, Ciorba MA.

Inflamm Bowel Dis. 2012 Jul;18(7):1214-20. doi: 10.1002/ibd.21849. Epub 2011 Aug 5.


COX-1(+/-)COX-2(-/-) genotype in mice is associated with shortened time to carotid artery occlusion through increased PAI-1.

Riehl TE, He L, Zheng L, Greco S, Tollefsen DM, Stenson WF.

J Thromb Haemost. 2011 Feb;9(2):350-60. doi: 10.1111/j.1538-7836.2010.04156.x.


Growth factor regulation of prostaglandin-endoperoxide synthase 2 (Ptgs2) expression in colonic mesenchymal stem cells.

Walker MR, Brown SL, Riehl TE, Stenson WF, Stappenbeck TS.

J Biol Chem. 2010 Feb 12;285(7):5026-39. doi: 10.1074/jbc.M109.032672. Epub 2009 Dec 14.


Regulation of colonic epithelial repair in mice by Toll-like receptors and hyaluronic acid.

Zheng L, Riehl TE, Stenson WF.

Gastroenterology. 2009 Dec;137(6):2041-51. doi: 10.1053/j.gastro.2009.08.055. Epub 2009 Sep 2.


Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively.

May R, Sureban SM, Hoang N, Riehl TE, Lightfoot SA, Ramanujam R, Wyche JH, Anant S, Houchen CW.

Stem Cells. 2009 Oct;27(10):2571-9. doi: 10.1002/stem.193.


Valganciclovir prevents cytomegalovirus reactivation in patients receiving alemtuzumab-based therapy.

O'Brien S, Ravandi F, Riehl T, Wierda W, Huang X, Tarrand J, O'Neal B, Kantarjian H, Keating M.

Blood. 2008 Feb 15;111(4):1816-9. Epub 2007 Nov 26.


Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury.

Brown SL, Riehl TE, Walker MR, Geske MJ, Doherty JM, Stenson WF, Stappenbeck TS.

J Clin Invest. 2007 Jan;117(1):258-69.


Azoxymethane protects intestinal stem cells and reduces crypt epithelial mitosis through a COX-1-dependent mechanism.

Riehl TE, George RJ, Sturmoski MA, May R, Dieckgraefe B, Anant S, Houchen CW.

Am J Physiol Gastrointest Liver Physiol. 2006 Dec;291(6):G1062-70. Epub 2006 Oct 12.


Rapid transient absorption and biliary secretion of enantiomeric cholesterol in hamsters.

Westover EJ, Lin X, Riehl TE, Ma L, Stenson WF, Covey DF, Ostlund RE Jr.

J Lipid Res. 2006 Nov;47(11):2374-81. Epub 2006 Aug 26.


Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression.

Anant S, Murmu N, Houchen CW, Mukhopadhyay D, Riehl TE, Young SG, Morrison AR, Stenson WF, Davidson NO.

Gastroenterology. 2004 Oct;127(4):1139-49.


Dynamic antagonism between RNA-binding protein CUGBP2 and cyclooxygenase-2-mediated prostaglandin E2 in radiation damage.

Murmu N, Jung J, Mukhopadhyay D, Houchen CW, Riehl TE, Stenson WF, Morrison AR, Arumugam T, Dieckgraefe BK, Anant S.

Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13873-8. Epub 2004 Sep 9.


TNFR1 mediates the radioprotective effects of lipopolysaccharide in the mouse intestine.

Riehl TE, Newberry RD, Lorenz RG, Stenson WF.

Am J Physiol Gastrointest Liver Physiol. 2004 Jan;286(1):G166-73. Epub 2003 Oct 2.


Amebic infection in the human colon induces cyclooxygenase-2.

Stenson WF, Zhang Z, Riehl T, Stanley SL Jr.

Infect Immun. 2001 May;69(5):3382-8.


Lipopolysaccharide is radioprotective in the mouse intestine through a prostaglandin-mediated mechanism.

Riehl T, Cohn S, Tessner T, Schloemann S, Stenson WF.

Gastroenterology. 2000 Jun;118(6):1106-16.


Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease.

Singer II, Kawka DW, Schloemann S, Tessner T, Riehl T, Stenson WF.

Gastroenterology. 1998 Aug;115(2):297-306.


Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease.

Singer II, Kawka DW, Scott S, Weidner JR, Mumford RA, Riehl TE, Stenson WF.

Gastroenterology. 1996 Oct;111(4):871-85.


Regulation of paracellular permeability in Caco-2 cell monolayers by protein kinase C.

Stenson WF, Easom RA, Riehl TE, Turk J.

Am J Physiol. 1993 Nov;265(5 Pt 1):G955-62.


Metabolism of oxygenated derivatives of arachidonic acid by Caco-2 cells.

Riehl TE, Turk J, Stenson WF.

J Lipid Res. 1992 Mar;33(3):323-31.


Efficacy and tolerability of a new antipsychotic compound (risperidone): results of a pilot study.

Möller HJ, Pelzer E, Kissling W, Riehl T, Wernicke T.

Pharmacopsychiatry. 1991 Nov;24(6):185-9.


A controlled study of the efficacy and safety of mianserin and maprotiline in outpatients with major depression.

Möller HJ, Riehl T, Dietzfelbinger T, Wernicke T.

Int Clin Psychopharmacol. 1991 Winter;6(3):179-92.


Metabolism of 15-hydroxyeicosatetraenoic acid by Caco-2 cells.

Riehl TE, Bass NM, Stenson WF.

J Lipid Res. 1990 May;31(5):773-80.


Nonelectrolyte permeability of liposomes of hydroxyfatty acid-containing phosphatidylcholines.

Isaacson Y, Riehl TE, Stenson WF.

Biochim Biophys Acta. 1989 Nov 27;986(2):295-300.


Doubleblind evaluation of the antimanic properties of carbamazepine as a comedication to haloperidol.

Möller HJ, Kissling W, Riehl T, Bäuml J, Binz U, Wendt G.

Prog Neuropsychopharmacol Biol Psychiatry. 1989;13(1-2):127-36.


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