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Ponatinib in the Treatment of Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Leukemia: Recommendations of a German Expert Consensus Panel with Focus on Cardiovascular Management.

Saussele S, Haverkamp W, Lang F, Koschmieder S, Kiani A, Jentsch-Ullrich K, Stegelmann F, Pfeifer H, La Rosée P, Goekbuget N, Rieger C, Waller CF, Franke GN, le Coutre P, Kirchmair R, Junghanss C.

Acta Haematol. 2019 Oct 7:1-15. doi: 10.1159/000501927. [Epub ahead of print] Review.


New Design of a Percutaneous Port System for Continuous Intraperitoneal Insulin Infusion.

Rieger C, Kurz K, Mueller-Hoffmann W, Gehr B, Liebl A.

J Diabetes Sci Technol. 2019 Nov;13(6):1158-1160. doi: 10.1177/1932296819855425. Epub 2019 Jun 13.


Vaccination of patients with haematological malignancies who did not have transplantations: guidelines from the 2017 European Conference on Infections in Leukaemia (ECIL 7).

Mikulska M, Cesaro S, de Lavallade H, Di Blasi R, Einarsdottir S, Gallo G, Rieger C, Engelhard D, Lehrnbecher T, Ljungman P, Cordonnier C; European Conference on Infections in Leukaemia group.

Lancet Infect Dis. 2019 Jun;19(6):e188-e199. doi: 10.1016/S1473-3099(18)30601-7. Epub 2019 Feb 8. Review. Erratum in: Lancet Infect Dis. 2019 Apr;19(4):e109.


Vaccination of haemopoietic stem cell transplant recipients: guidelines of the 2017 European Conference on Infections in Leukaemia (ECIL 7).

Cordonnier C, Einarsdottir S, Cesaro S, Di Blasi R, Mikulska M, Rieger C, de Lavallade H, Gallo G, Lehrnbecher T, Engelhard D, Ljungman P; European Conference on Infections in Leukaemia group.

Lancet Infect Dis. 2019 Jun;19(6):e200-e212. doi: 10.1016/S1473-3099(18)30600-5. Epub 2019 Feb 8. Review.


Diagnosis of invasive fungal diseases in haematology and oncology: 2018 update of the recommendations of the infectious diseases working party of the German society for hematology and medical oncology (AGIHO).

Ruhnke M, Behre G, Buchheidt D, Christopeit M, Hamprecht A, Heinz W, Heussel CP, Horger M, Kurzai O, Karthaus M, Löffler J, Maschmeyer G, Penack O, Rieger C, Rickerts V, Ritter J, Schmidt-Hieber M, Schuelper N, Schwartz S, Ullmann A, Vehreschild JJ, von Lilienfeld-Toal M, Weber T, Wolf HH.

Mycoses. 2018 Nov;61(11):796-813. doi: 10.1111/myc.12838. Epub 2018 Sep 3. Review.


Burden of Oral Mucositis: A Systematic Review and Implications for Future Research.

Berger K, Schopohl D, Bollig A, Strobach D, Rieger C, Rublee D, Ostermann H.

Oncol Res Treat. 2018;41(6):399-405. doi: 10.1159/000487085. Epub 2018 May 3.


Anti-infective vaccination strategies in patients with hematologic malignancies or solid tumors-Guideline of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO).

Rieger CT, Liss B, Mellinghoff S, Buchheidt D, Cornely OA, Egerer G, Heinz WJ, Hentrich M, Maschmeyer G, Mayer K, Sandherr M, Silling G, Ullmann A, Vehreschild MJGT, von Lilienfeld-Toal M, Wolf HH, Lehners N; German Society of Hematology and Medical Oncology Infectious Diseases Working Group (AGIHO).

Ann Oncol. 2018 Jun 1;29(6):1354-1365. doi: 10.1093/annonc/mdy117. Review.


An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment.

Huebner D, Rieger C, Bergmann R, Ullrich M, Meister S, Toma M, Wiedemuth R, Temme A, Novotny V, Wirth MP, Bachmann M, Pietzsch J, Fuessel S.

BMC Cancer. 2017 Nov 23;17(1):790. doi: 10.1186/s12885-017-3778-3.


Induction of alpha-methylacyl-CoA racemase by miR-138 via up-regulation of β-catenin in prostate cancer cells.

Erdmann K, Kaulke K, Rieger C, Wirth MP, Fuessel S.

J Cancer Res Clin Oncol. 2017 Nov;143(11):2201-2210. doi: 10.1007/s00432-017-2484-5. Epub 2017 Jul 24.


Systematic evaluation of oligodeoxynucleotide binding and hybridization to modified multi-walled carbon nanotubes.

Kaufmann A, Hampel S, Rieger C, Kunhardt D, Schendel D, Füssel S, Schwenzer B, Erdmann K.

J Nanobiotechnology. 2017 Jul 17;15(1):53. doi: 10.1186/s12951-017-0288-z.


Randomized comparison of liposomal amphotericin B versus placebo to prevent invasive mycoses in acute lymphoblastic leukaemia.

Cornely OA, Leguay T, Maertens J, Vehreschild MJGT, Anagnostopoulos A, Castagnola C, Verga L, Rieger C, Kondakci M, Härter G, Duarte RF, Allione B, Cordonnier C, Heussel CP, Morrissey CO, Agrawal SG, Donnelly JP, Bresnik M, Hawkins MJ, Garner W, Gökbuget N; AmBiGuard Study Group.

J Antimicrob Chemother. 2017 Aug 1;72(8):2359-2367. doi: 10.1093/jac/dkx133.


Antifungal prophylaxis in newly diagnosed AML patients-Adherence to guidelines and feasibility in a real life setting.

Berking S, Doedens D, Horns H, Fiegl M, Ostermann H, Rieger CT.

Mycoses. 2017 Sep;60(9):600-606. doi: 10.1111/myc.12635. Epub 2017 May 15.


Analysis of FOXP3+ regulatory T cell subpopulations in peripheral blood and tissue of patients with systemic lupus erythematosus.

Schmidt A, Rieger CC, Venigalla RK, Éliás S, Max R, Lorenz HM, Gröne HJ, Krammer PH, Kuhn A.

Immunol Res. 2017 Apr;65(2):551-563. doi: 10.1007/s12026-017-8904-4.


Blood Product Supply in Germany: The Impact of Apheresis and Pooled Platelet Concentrates.

Berger K, Schopohl D, Wittmann G, Schramm W, Ostermann H, Rieger C.

Transfus Med Hemother. 2016 Nov;43(6):389-394. Epub 2016 Sep 15.


Influenza virus infections in patients with malignancies -- characteristics and outcome of the season 2014/15. A survey conducted by the Infectious Diseases Working Party (AGIHO) of the German Society of Haematology and Medical Oncology (DGHO).

Hermann B, Lehners N, Brodhun M, Boden K, Hochhaus A, Kochanek M, Meckel K, Mayer K, Rachow T, Rieger C, Schalk E, Weber T, Schmeier-Jürchott A, Schlattmann P, Teschner D, von Lilienfeld-Toal M.

Eur J Clin Microbiol Infect Dis. 2017 Mar;36(3):565-573. doi: 10.1007/s10096-016-2833-3. Epub 2016 Nov 12.


Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology.

von Lilienfeld-Toal M, Berger A, Christopeit M, Hentrich M, Heussel CP, Kalkreuth J, Klein M, Kochanek M, Penack O, Hauf E, Rieger C, Silling G, Vehreschild M, Weber T, Wolf HH, Lehners N, Schalk E, Mayer K.

Eur J Cancer. 2016 Nov;67:200-212. doi: 10.1016/j.ejca.2016.08.015. Epub 2016 Sep 25. Review.


MiR-26a and miR-138 block the G1/S transition by targeting the cell cycle regulating network in prostate cancer cells.

Erdmann K, Kaulke K, Rieger C, Salomo K, Wirth MP, Fuessel S.

J Cancer Res Clin Oncol. 2016 Nov;142(11):2249-61. doi: 10.1007/s00432-016-2222-4. Epub 2016 Aug 25.


[Lymphoepithelial sialadenitis (LESA)-like Thymic hyperplasia: A case report].

Arndt B, Gaiser T, Marx A, Rieger C.

Dtsch Med Wochenschr. 2016 Jul;141(14):1026-9. doi: 10.1055/s-0041-109106. Epub 2016 Jul 12. German.


Microenvironmental oxygen partial pressure in acute myeloid leukemia: Is there really a role for hypoxia?

Rieger CT, Fiegl M.

Exp Hematol. 2016 Jul;44(7):578-82. doi: 10.1016/j.exphem.2016.04.008. Epub 2016 Apr 23. Review.


Reactivation of polyomavirus in the genitourinary tract is significantly associated with severe GvHD and oral mucositis following allogeneic stem cell transplantation.

Peterson L, Ostermann H, Fiegl M, Tischer J, Jaeger G, Rieger CT.

Infection. 2016 Aug;44(4):483-90. doi: 10.1007/s15010-016-0872-4. Epub 2016 Jan 20.


Weight Loss and Decrease of Body Mass Index during Allogeneic Stem Cell Transplantation Are Common Events with Limited Clinical Impact.

Rieger CT, Wischumerski I, Rust C, Fiegl M.

PLoS One. 2015 Dec 18;10(12):e0145445. doi: 10.1371/journal.pone.0145445. eCollection 2015.


IL-8 as mediator in the microenvironment-leukaemia network in acute myeloid leukaemia.

Kuett A, Rieger C, Perathoner D, Herold T, Wagner M, Sironi S, Sotlar K, Horny HP, Deniffel C, Drolle H, Fiegl M.

Sci Rep. 2015 Dec 17;5:18411. doi: 10.1038/srep18411.


Microenvironmental hypoxia regulates FLT3 expression and biology in AML.

Sironi S, Wagner M, Kuett A, Drolle H, Polzer H, Spiekermann K, Rieger C, Fiegl M.

Sci Rep. 2015 Nov 30;5:17550. doi: 10.1038/srep17550.


Antisense- and siRNA-mediated inhibition of the anti-apoptotic gene Bcl-xL for chemosensitization of bladder cancer cells.

Rieger C, Huebner D, Temme A, Wirth MP, Fuessel S.

Int J Oncol. 2015 Sep;47(3):1121-30. doi: 10.3892/ijo.2015.3096. Epub 2015 Jul 20.


Miliary pattern of brain metastases - a case report of a hyperacute onset in a patient with malignant melanoma documented by magnetic resonance imaging.

Reiter FP, Giessen-Jung C, Dorostkar MM, Ertl-Wagner B, Denk GU, Heck S, Rieger CT, Pfister HW, op den Winkel M.

Radiat Oncol. 2015 Jul 19;10:148. doi: 10.1186/s13014-015-0459-8.


Tunable Protein Stabilization In Vivo Mediated by Shield-1 in Transgenic Medaka.

Froschauer A, Kube L, Kegler A, Rieger C, Gutzeit HO.

PLoS One. 2015 Jul 6;10(7):e0131252. doi: 10.1371/journal.pone.0131252. eCollection 2015.


Virus infection in HLA-haploidentical hematopoietic stem cell transplantation: incidence in the context of immune recovery in two different transplantation settings.

Tischer J, Engel N, Fritsch S, Prevalsek D, Hubmann M, Schulz C, Zoellner AK, Bücklein V, Reibke R, Mumm F, Rieger CT, Hill W, Ledderose G, Stemmler HJ, Köhnke T, Jäger G, Kolb HJ, Schmid C, Moosmann A, Hausmann A.

Ann Hematol. 2015 Oct;94(10):1677-88. doi: 10.1007/s00277-015-2423-y. Epub 2015 Jun 10.


Hypoxia regulates proliferation of acute myeloid leukemia and sensitivity against chemotherapy.

Drolle H, Wagner M, Vasold J, Kütt A, Deniffel C, Sotlar K, Sironi S, Herold T, Rieger C, Fiegl M.

Leuk Res. 2015 Jul;39(7):779-85. doi: 10.1016/j.leukres.2015.04.019. Epub 2015 May 7.


Economic and clinical aspects of intravenous versus oral busulfan in adult patients for conditioning prior to HSCT.

Berger K, Schopohl D, Rieger C, Ostermann H.

Support Care Cancer. 2015 Dec;23(12):3447-54. doi: 10.1007/s00520-015-2695-8. Epub 2015 Mar 17.


Sequential therapy combining clofarabine and T-cell-replete HLA-haploidentical haematopoietic SCT is feasible and shows efficacy in the treatment of refractory or relapsed aggressive lymphoma.

Zoellner AK, Fritsch S, Prevalsek D, Engel N, Hubmann M, Reibke R, Rieger CT, Hellmuth JC, Haas M, Mumm F, Herold T, Ledderose G, Hiddemann W, Dreyling M, Hausmann A, Tischer J.

Bone Marrow Transplant. 2015 May;50(5):679-84. doi: 10.1038/bmt.2014.328. Epub 2015 Feb 2.


Characterization of different carbon nanotubes for the development of a mucoadhesive drug delivery system for intravesical treatment of bladder cancer.

Rieger C, Kunhardt D, Kaufmann A, Schendel D, Huebner D, Erdmann K, Propping S, Wirth MP, Schwenzer B, Fuessel S, Hampel S.

Int J Pharm. 2015 Feb 20;479(2):357-63. doi: 10.1016/j.ijpharm.2015.01.017. Epub 2015 Jan 13.


Applicability of the EORTC/MSG criteria for IFD in clinical practice.

Rieger H, Lustig D, Barlow S, Ostermann H, Fiegl M, Peterson L, Rieger CT.

Ann Hematol. 2015 May;94(5):847-55. doi: 10.1007/s00277-014-2282-y. Epub 2014 Dec 30.


The bone marrow microenvironment is a critical player in the NK cell response against acute myeloid leukaemia in vitro.

Vasold J, Wagner M, Drolle H, Deniffel C, Kütt A, Oostendorp R, Sironi S, Rieger C, Fiegl M.

Leuk Res. 2015 Feb;39(2):257-62. doi: 10.1016/j.leukres.2014.12.001. Epub 2014 Dec 9.


Chemosensitizing effects of carbon-based nanomaterials in cancer cells: enhanced apoptosis and inhibition of proliferation as underlying mechanisms.

Erdmann K, Ringel J, Hampel S, Rieger C, Huebner D, Wirth MP, Fuessel S.

Nanotechnology. 2014 Oct 10;25(40):405102.


Introduction to the special issue on resilient control architectures and systems.

Rieger CG, Scheidt DH, Smart WD.

IEEE Trans Cybern. 2014 Nov;44(11):1944-6. doi: 10.1109/TCYB.2014.2339951. No abstract available.


What's new in diagnosis and antimicrobial therapy of febrile neutropenic patients with lung infiltrates?

Rieger C, Barlow S, Maschmeyer G.

Intensive Care Med. 2014 Oct;40(10):1549-52. doi: 10.1007/s00134-014-3368-7. Epub 2014 Jun 28. No abstract available.


Primary prophylaxis of invasive fungal infections in patients with haematologic malignancies. 2014 update of the recommendations of the Infectious Diseases Working Party of the German Society for Haematology and Oncology.

Tacke D, Buchheidt D, Karthaus M, Krause SW, Maschmeyer G, Neumann S, Ostermann H, Penack O, Rieger C, Ruhnke M, Sandherr M, Schweer KE, Ullmann AJ, Cornely OA.

Ann Hematol. 2014 Sep;93(9):1449-56. doi: 10.1007/s00277-014-2108-y. Epub 2014 Jun 21. Review.


Severe cytokine release syndrome after the first dose of Brentuximab Vedotin in a patient with relapsed systemic anaplastic large cell lymphoma (sALCL): a case report and review of literature.

Alig SK, Dreyling M, Seppi B, Aulinger B, Witkowski L, Rieger CT.

Eur J Haematol. 2015 Jun;94(6):554-7. doi: 10.1111/ejh.12396. Epub 2014 Jul 2. Review.


FN-DFE: fuzzy-neural data fusion engine for enhanced resilient state-awareness of hybrid energy systems.

Wijayasekara D, Linda O, Manic M, Rieger C.

IEEE Trans Cybern. 2014 Nov;44(11):2065-75. doi: 10.1109/TCYB.2014.2323891. Epub 2014 May 30.


Diagnosis and antimicrobial therapy of lung infiltrates in febrile neutropenic patients (allogeneic SCT excluded): updated guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO).

Maschmeyer G, Carratalà J, Buchheidt D, Hamprecht A, Heussel CP, Kahl C, Lorenz J, Neumann S, Rieger C, Ruhnke M, Salwender H, Schmidt-Hieber M, Azoulay E; Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology.

Ann Oncol. 2015 Jan;26(1):21-33. doi: 10.1093/annonc/mdu192. Epub 2014 May 15.


Second haematopoietic SCT using HLA-haploidentical donors in patients with relapse of acute leukaemia after a first allogeneic transplantation.

Tischer J, Engel N, Fritsch S, Prevalsek D, Hubmann M, Schulz C, Zoellner AK, Bücklein V, Lippl S, Reibke R, Rieger CT, Ledderose G, Stemmler HJ, Hiddemann W, Schmid C, Hausmann A.

Bone Marrow Transplant. 2014 Jul;49(7):895-901. doi: 10.1038/bmt.2014.83. Epub 2014 May 12.


Physiological hypoxia prevents bile salt-induced apoptosis in human and rat hepatocytes.

Hohenester S, Vennegeerts T, Wagner M, Wimmer R, Drolle H, Rieger C, Denk GU, Rust C, Fiegl M.

Liver Int. 2014 Sep;34(8):1224-31. doi: 10.1111/liv.12368. Epub 2013 Nov 20.


Chemomodulation of sequential high-dose cytarabine by fludarabine in relapsed or refractory acute myeloid leukemia: a randomized trial of the AMLCG.

Fiegl M, Unterhalt M, Kern W, Braess J, Spiekermann K, Staib P, Grüneisen A, Wörmann B, Schöndube D, Serve H, Reichle A, Hentrich M, Schiel X, Sauerland C, Heinecke A, Rieger C, Beelen D, Berdel WE, Büchner T, Hiddemann W; German AML Cooperative Group (AMLCG).

Leukemia. 2014 May;28(5):1001-7. doi: 10.1038/leu.2013.297. Epub 2013 Oct 22.


CD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L.

Price JD, Beauchamp NM, Rahir G, Zhao Y, Rieger CC, Lau-Kilby AW, Tarbell KV.

J Leukoc Biol. 2014 Feb;95(2):325-36. doi: 10.1189/jlb.0113013. Epub 2013 Sep 30.


Interferon-α abrogates the suppressive effect of apoptotic cells on dendritic cells in an in vitro model of systemic lupus erythematosus pathogenesis.

Abeler-Dörner L, Rieger CC, Berger B, Weyd H, Gräf D, Pfrang S, Tarner IH, Schwarting A, Lorenz HM, Müller-Ladner U, Krammer PH, Kuhn A.

J Rheumatol. 2013 Oct;40(10):1683-96. doi: 10.3899/jrheum.121299. Epub 2013 Sep 15.


Treatment of invasive fungal infections in cancer patients-updated recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO).

Mousset S, Buchheidt D, Heinz W, Ruhnke M, Cornely OA, Egerer G, Krüger W, Link H, Neumann S, Ostermann H, Panse J, Penack O, Rieger C, Schmidt-Hieber M, Silling G, Südhoff T, Ullmann AJ, Wolf HH, Maschmeyer G, Böhme A.

Ann Hematol. 2014 Jan;93(1):13-32. doi: 10.1007/s00277-013-1867-1. Epub 2013 Sep 12.


Posaconazole prophylaxis--impact on incidence of invasive fungal disease and antifungal treatment in haematological patients.

Peterson L, Ostermann J, Rieger H, Ostermann H, Rieger CT.

Mycoses. 2013 Nov;56(6):651-8. doi: 10.1111/myc.12086. Epub 2013 May 26.


oct4-EGFP reporter gene expression marks the stem cells in embryonic development and in adult gonads of transgenic medaka.

Froschauer A, Khatun MM, Sprott D, Franz A, Rieger C, Pfennig F, Gutzeit HO.

Mol Reprod Dev. 2013 Jan;80(1):48-58. doi: 10.1002/mrd.22135. Epub 2012 Dec 27.


Inflammatory markers in induced sputum of school children born before 32 completed weeks of gestation.

Teig N, Allali M, Rieger C, Hamelmann E.

J Pediatr. 2012 Dec;161(6):1085-90. doi: 10.1016/j.jpeds.2012.06.007. Epub 2012 Aug 3.


Treatment cost of invasive fungal disease (Ifd) in patients with acute myelogenous leukaemia (Aml) or myelodysplastic syndrome (Mds) in German hospitals.

Rieger CT, Cornely OA, Hoppe-Tichy T, Kiehl M, Knoth H, Thalheimer M, Schuler U, Ullmann AJ, Ehlken B, Ostermann H.

Mycoses. 2012 Nov;55(6):514-20. doi: 10.1111/j.1439-0507.2012.02193.x. Epub 2012 Apr 3.


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