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CYP2D6 as a treatment decision aid for ER-positive non-metastatic breast cancer patients: a systematic review with accompanying clinical practice guidelines.

Drögemöller BI, Wright GEB, Shih J, Monzon JG, Gelmon KA, Ross CJD, Amstutz U, Carleton BC; CPNDS Clinical Recommendations Group.

Breast Cancer Res Treat. 2019 Feb;173(3):521-532. doi: 10.1007/s10549-018-5027-0. Epub 2018 Nov 8.


Rare loss of function variants in candidate genes and risk of colorectal cancer.

Rosenthal EA, Shirts BH, Amendola LM, Horike-Pyne M, Robertson PD, Hisama FM, Bennett RL, Dorschner MO, Nickerson DA, Stanaway IB, Nassir R, Vickers KT, Li C, Grady WM, Peters U, Jarvik GP; NHLBI GO Exome Sequencing Project.

Hum Genet. 2018 Oct;137(10):795-806. doi: 10.1007/s00439-018-1938-4. Epub 2018 Sep 28.


Hair cortisol analysis: An update on methodological considerations and clinical applications.

Greff MJE, Levine JM, Abuzgaia AM, Elzagallaai AA, Rieder MJ, van Uum SHM.

Clin Biochem. 2019 Jan;63:1-9. doi: 10.1016/j.clinbiochem.2018.09.010. Epub 2018 Sep 24. Review.


Phenytoin activates Smad3 phosphorylation and periostin expression in drug-induced gingival enlargement.

Kim SS, Nikoloudaki G, Darling M, Rieder MJ, Hamilton DW.

Histol Histopathol. 2018 Dec;33(12):1287-1298. doi: 10.14670/HH-18-015. Epub 2018 Jun 19.


HIV-1 tat expression and sulphamethoxazole hydroxylamine mediated oxidative stress alter the disulfide proteome in Jurkat T cells.

Adeyanju K, Bend JR, Rieder MJ, Dekaban GA.

Virol J. 2018 May 9;15(1):82. doi: 10.1186/s12985-018-0991-x.


Pharmacokinetic studies in children: recommendations for practice and research.

Barker CIS, Standing JF, Kelly LE, Hanly Faught L, Needham AC, Rieder MJ, de Wildt SN, Offringa M.

Arch Dis Child. 2018 Jul;103(7):695-702. doi: 10.1136/archdischild-2017-314506. Epub 2018 Apr 19. Review.


Health-related quality of life in children with cutaneous adverse drug reactions.

Del Pozzo-Magaña BR, Lazo-Langner A, Rieder MJ.

Pediatr Dermatol. 2017 Nov;34(6):e341-e342. doi: 10.1111/pde.13253. Epub 2017 Sep 21.


Pharmacogenomic screening for anthracycline-induced cardiotoxicity in childhood cancer.

Aminkeng F, Ross CJD, Rassekh SR, Rieder MJ, Bhavsar AP, Sanatani S, Bernstein D, Hayden MR, Amstutz U, Carleton BC.

Br J Clin Pharmacol. 2017 May;83(5):1143-1145. doi: 10.1111/bcp.13218. Epub 2017 Mar 19. No abstract available.


Adverse Drug Reactions in Children: The Double-Edged Sword of Therapeutics.

Elzagallaai AA, Greff M, Rieder MJ.

Clin Pharmacol Ther. 2017 Jun;101(6):725-735. doi: 10.1002/cpt.677. Epub 2017 Apr 29. Review.


Idiosyncratic drug reactions and membranous glomerulopathy.

Kirpalani A, Rieder MJ, Bax KC, Filler G.

BMJ Case Rep. 2017 Jan 30;2017. pii: bcr2016218496. doi: 10.1136/bcr-2016-218496.


The Risk of Adverse Pregnancy Outcome After First Trimester Exposure to H1 Antihistamines: A Systematic Review and Meta-Analysis.

Etwel F, Faught LH, Rieder MJ, Koren G.

Drug Saf. 2017 Feb;40(2):121-132. doi: 10.1007/s40264-016-0479-9. Review.


Averting the foul taste of pediatric medicines improves adherence and can be lifesaving - Pheburane® (sodium phenylbutyrate).

Koren G, Rieder MJ, Amitai Y.

Patient Prefer Adherence. 2016 Oct 21;10:2141-2144. eCollection 2016. Review.


Oral morphine dosing predictions based on single dose in healthy children undergoing surgery.

Dawes JM, Cooke EM, Hannam JA, Brand KA, Winton P, Jimenez-Mendez R, Aleksa K, Lauder GR, Carleton BC, Koren G, Rieder MJ, Anderson BJ, Montgomery CJ.

Paediatr Anaesth. 2017 Jan;27(1):28-36. doi: 10.1111/pan.13020. Epub 2016 Oct 25.


An International Asset Map of Clinicians, Educators, and Researchers Pursuing Better Medicine Use in Children: Initial Findings.

MacLeod SM, Greff M, Knoppert DC, Ito S, Rieder MJ.

Clin Pharmacol Ther. 2017 Feb;101(2):274-280. doi: 10.1002/cpt.460. Epub 2016 Sep 28.


Recommendations for genetic testing to reduce the incidence of anthracycline-induced cardiotoxicity.

Aminkeng F, Ross CJ, Rassekh SR, Hwang S, Rieder MJ, Bhavsar AP, Smith A, Sanatani S, Gelmon KA, Bernstein D, Hayden MR, Amstutz U, Carleton BC; CPNDS Clinical Practice Recommendations Group.

Br J Clin Pharmacol. 2016 Sep;82(3):683-95. doi: 10.1111/bcp.13008. Epub 2016 Jun 30. Review.


Exposure-based Interventions for the management of individuals with high levels of needle fear across the lifespan: a clinical practice guideline and call for further research.

McMurtry CM, Taddio A, Noel M, Antony MM, Chambers CT, Asmundson GJ, Pillai Riddell R, Shah V, MacDonald NE, Rogers J, Bucci LM, Mousmanis P, Lang E, Halperin S, Bowles S, Halpert C, Ipp M, Rieder MJ, Robson K, Uleryk E, Votta Bleeker E, Dubey V, Hanrahan A, Lockett D, Scott J.

Cogn Behav Ther. 2016 Apr;45(3):217-35. doi: 10.1080/16506073.2016.1157204. Epub 2016 Mar 23.


Is the medical use of cannabis a therapeutic option for children?

Rieder MJ; Canadian Paediatric Society, Drug Therapy and Hazardous Substances Committee.

Paediatr Child Health. 2016 Jan-Feb;21(1):31-4.


Sleep-promoting medications in children: physician prescribing habits in Southwestern Ontario, Canada.

Bock DE, Roach-Fox E, Seabrook JA, Rieder MJ, Matsui D.

Sleep Med. 2016 Jan;17:52-6. doi: 10.1016/j.sleep.2015.10.003. Epub 2015 Oct 20.


Attenuation of Oxidative Stress in HEK 293 Cells by the TCM Constituents Schisanhenol, Baicalein, Resveratrol or Crocetin and Two Defined Mixtures.

Bend JR, Xia XY, Chen D, Awaysheh A, Lo A, Rieder MJ, Rylett RJ.

J Pharm Pharm Sci. 2015;18(4):661-82.


Annotation of pseudogenic gene segments by massively parallel sequencing of rearranged lymphocyte receptor loci.

Dean J, Emerson RO, Vignali M, Sherwood AM, Rieder MJ, Carlson CS, Robins HS.

Genome Med. 2015 Nov 23;7:123. doi: 10.1186/s13073-015-0238-z.


Reducing pain during vaccine injections: clinical practice guideline.

Taddio A, McMurtry CM, Shah V, Riddell RP, Chambers CT, Noel M, MacDonald NE, Rogers J, Bucci LM, Mousmanis P, Lang E, Halperin SA, Bowles S, Halpert C, Ipp M, Asmundson GJG, Rieder MJ, Robson K, Uleryk E, Antony MM, Dubey V, Hanrahan A, Lockett D, Scott J, Bleeker EV; HELPinKids&Adults.

CMAJ. 2015 Sep 22;187(13):975-982. doi: 10.1503/cmaj.150391. Epub 2015 Aug 24. No abstract available.


Nifedipine and phenytoin induce matrix synthesis, but not proliferation, in intact human gingival connective tissue ex vivo.

Kim SS, Michelsons S, Creber K, Rieder MJ, Hamilton DW.

J Cell Commun Signal. 2015 Dec;9(4):361-75. doi: 10.1007/s12079-015-0303-9. Epub 2015 Aug 23.


High-throughput pairing of T cell receptor α and β sequences.

Howie B, Sherwood AM, Berkebile AD, Berka J, Emerson RO, Williamson DW, Kirsch I, Vignali M, Rieder MJ, Carlson CS, Robins HS.

Sci Transl Med. 2015 Aug 19;7(301):301ra131. doi: 10.1126/scitranslmed.aac5624. Erratum in: Sci Transl Med. 2015 Oct 14;7(309):309er7.


Correction: Exome Sequencing of Phenotypic Extremes Identifies CAV2 and TMC6 as Interacting Modifiers of Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis.

Emond MJ, Louie T, Emerson J, Chong JX, Mathias RA, Knowles MR, Rieder MJ, Tabor HK, Nickerson DA, Barnes KC; NHLBI GO Exome Sequencing Project, Go L, Gibson RL, Bamshad MJ.

PLoS Genet. 2015 Aug 18;11(8):e1005424. doi: 10.1371/journal.pgen.1005424. eCollection 2015 Aug. No abstract available.


A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer.

Aminkeng F, Bhavsar AP, Visscher H, Rassekh SR, Li Y, Lee JW, Brunham LR, Caron HN, van Dalen EC, Kremer LC, van der Pal HJ, Amstutz U, Rieder MJ, Bernstein D, Carleton BC, Hayden MR, Ross CJ; Canadian Pharmacogenomics Network for Drug Safety Consortium.

Nat Genet. 2015 Sep;47(9):1079-84. doi: 10.1038/ng.3374. Epub 2015 Aug 3.


Genetic variants in SLC22A17 and SLC22A7 are associated with anthracycline-induced cardiotoxicity in children.

Visscher H, Rassekh SR, Sandor GS, Caron HN, van Dalen EC, Kremer LC, van der Pal HJ, Rogers PC, Rieder MJ, Carleton BC, Hayden MR, Ross CJ; CPNDS consortium.

Pharmacogenomics. 2015;16(10):1065-76. doi: 10.2217/pgs.15.61. Epub 2015 Jul 31.


Clinical Practice Recommendations on Genetic Testing of CYP2C9 and VKORC1 Variants in Warfarin Therapy.

Shaw K, Amstutz U, Kim RB, Lesko LJ, Turgeon J, Michaud V, Hwang S, Ito S, Ross C, Carleton BC; CPNDS Clinical Recommendation Group.

Ther Drug Monit. 2015 Aug;37(4):428-36. doi: 10.1097/FTD.0000000000000192. Review.


Exome Sequencing of Phenotypic Extremes Identifies CAV2 and TMC6 as Interacting Modifiers of Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis.

Emond MJ, Louie T, Emerson J, Chong JX, Mathias RA, Knowles MR, Rieder MJ, Tabor HK, Nickerson DA, Barnes KC; NHLBI GO Exome Sequencing Project, Go L, Gibson RL, Bamshad MJ.

PLoS Genet. 2015 Jun 5;11(6):e1005273. doi: 10.1371/journal.pgen.1005273. eCollection 2015 Jun. Erratum in: PLoS Genet. 2015 Aug;11(8):e1005424.


'Nosodes' are no substitute for vaccines.

Rieder MJ, Robinson JL.

Paediatr Child Health. 2015 May;20(4):219-22. English, French.


Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project.

Auer PL, Nalls M, Meschia JF, Worrall BB, Longstreth WT Jr, Seshadri S, Kooperberg C, Burger KM, Carlson CS, Carty CL, Chen WM, Cupples LA, DeStefano AL, Fornage M, Hardy J, Hsu L, Jackson RD, Jarvik GP, Kim DS, Lakshminarayan K, Lange LA, Manichaikul A, Quinlan AR, Singleton AB, Thornton TA, Nickerson DA, Peters U, Rich SS; National Heart, Lung, and Blood Institute Exome Sequencing Project.

JAMA Neurol. 2015 Jul;72(7):781-8. doi: 10.1001/jamaneurol.2015.0582.


A Compartmental Analysis for Morphine and Its Metabolites in Young Children After a Single Oral Dose.

Velez de Mendizabal N, Jimenez-Mendez R, Cooke E, Montgomery CJ, Dawes J, Rieder MJ, Aleksa K, Koren G, Jacobo-Cabral CO, Gonzalez-Ramirez R, Castañeda-Hernandez G, Carleton BC.

Clin Pharmacokinet. 2015 Oct;54(10):1083-90. doi: 10.1007/s40262-015-0256-4.


Hair cortisol as a biomarker of stress in the 2011 Libyan war.

Etwel F, Russell E, Rieder MJ, Van Uum SH, Koren G.

Clin Invest Med. 2014 Dec 1;37(6):E403-8.


Propranolol therapy for infantile hemangioma is less toxic but longer in duration than corticosteroid therapy.

Sawa K, Yazdani A, Rieder MJ, Filler G.

Plast Surg (Oakv). 2014 Winter;22(4):233-6.


Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.

Do R, Stitziel NO, Won HH, Jørgensen AB, Duga S, Angelica Merlini P, Kiezun A, Farrall M, Goel A, Zuk O, Guella I, Asselta R, Lange LA, Peloso GM, Auer PL; NHLBI Exome Sequencing Project, Girelli D, Martinelli N, Farlow DN, DePristo MA, Roberts R, Stewart AF, Saleheen D, Danesh J, Epstein SE, Sivapalaratnam S, Hovingh GK, Kastelein JJ, Samani NJ, Schunkert H, Erdmann J, Shah SH, Kraus WE, Davies R, Nikpay M, Johansen CT, Wang J, Hegele RA, Hechter E, Marz W, Kleber ME, Huang J, Johnson AD, Li M, Burke GL, Gross M, Liu Y, Assimes TL, Heiss G, Lange EM, Folsom AR, Taylor HA, Olivieri O, Hamsten A, Clarke R, Reilly DF, Yin W, Rivas MA, Donnelly P, Rossouw JE, Psaty BM, Herrington DM, Wilson JG, Rich SS, Bamshad MJ, Tracy RP, Cupples LA, Rader DJ, Reilly MP, Spertus JA, Cresci S, Hartiala J, Tang WH, Hazen SL, Allayee H, Reiner AP, Carlson CS, Kooperberg C, Jackson RD, Boerwinkle E, Lander ES, Schwartz SM, Siscovick DS, McPherson R, Tybjaerg-Hansen A, Abecasis GR, Watkins H, Nickerson DA, Ardissino D, Sunyaev SR, O'Donnell CJ, Altshuler D, Gabriel S, Kathiresan S.

Nature. 2015 Feb 5;518(7537):102-6. doi: 10.1038/nature13917. Epub 2014 Dec 10.


Rare variation facilitates inferences of fine-scale population structure in humans.

O'Connor TD, Fu W; NHLBI GO Exome Sequencing Project; ESP Population Genetics and Statistical Analysis Working Group, Emily Turner, Mychaleckyj JC, Logsdon B, Auer P, Carlson CS, Leal SM, Smith JD, Rieder MJ, Bamshad MJ, Nickerson DA, Akey JM.

Mol Biol Evol. 2015 Mar;32(3):653-60. doi: 10.1093/molbev/msu326. Epub 2014 Nov 21.


Bronchiolitis: Recommendations for diagnosis, monitoring and management of children one to 24 months of age.

Friedman JN, Rieder MJ, Walton JM; Canadian Paediatric Society, Acute Care Committee, Drug Therapy and Hazardous Substances Committee.

Paediatr Child Health. 2014 Nov;19(9):485-98. English, French.


Drug-induced acute kidney injury in children.

Faught LN, Greff MJ, Rieder MJ, Koren G.

Br J Clin Pharmacol. 2015 Oct;80(4):901-9. doi: 10.1111/bcp.12554. Epub 2015 Jun 1. Review.


Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial.

Poonai N, Bhullar G, Lin K, Papini A, Mainprize D, Howard J, Teefy J, Bale M, Langford C, Lim R, Stitt L, Rieder MJ, Ali S.

CMAJ. 2014 Dec 9;186(18):1358-63. doi: 10.1503/cmaj.140907. Epub 2014 Oct 27.


Oral morphine weaning for neonatal abstinence syndrome at home compared with in-hospital: an observational cohort study.

Kelly LE, Knoppert D, Roukema H, Rieder MJ, Koren G.

Paediatr Drugs. 2015 Apr;17(2):151-7. doi: 10.1007/s40272-014-0096-y.


In vitro testing for diagnosis of idiosyncratic adverse drug reactions: Implications for pathophysiology.

Elzagallaai AA, Rieder MJ.

Br J Clin Pharmacol. 2015 Oct;80(4):889-900. doi: 10.1111/bcp.12505. Epub 2015 Jun 1. Review.


Rapid resolution of tacrolimus intoxication-induced AKI with a corticosteroid and phenytoin.

Bax K, Tijssen J, Rieder MJ, Filler G.

Ann Pharmacother. 2014 Nov;48(11):1525-8. doi: 10.1177/1060028014546184. Epub 2014 Aug 7.


Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results.

Tabor HK, Auer PL, Jamal SM, Chong JX, Yu JH, Gordon AS, Graubert TA, O'Donnell CJ, Rich SS, Nickerson DA; NHLBI Exome Sequencing Project, Bamshad MJ.

Am J Hum Genet. 2014 Aug 7;95(2):183-93. doi: 10.1016/j.ajhg.2014.07.006. Epub 2014 Jul 31.


Quality of life in children with adverse drug reactions: a narrative and systematic review.

Del Pozzo-Magaña BR, Rieder MJ, Lazo-Langner A.

Br J Clin Pharmacol. 2015 Oct;80(4):827-33. doi: 10.1111/bcp.12423. Epub 2015 Jul 2. Review.


Pharmacogenomics and adverse drug reactions in children.

Rieder MJ, Carleton B.

Front Genet. 2014 Apr 16;5:78. doi: 10.3389/fgene.2014.00078. eCollection 2014. Review.


Public perceptions of pharmacogenetics.

Zhang SC, Bruce C, Hayden M, Rieder MJ.

Pediatrics. 2014 May;133(5):e1258-67. doi: 10.1542/peds.2013-1416.


Recommendations for HLA-B*15:02 and HLA-A*31:01 genetic testing to reduce the risk of carbamazepine-induced hypersensitivity reactions.

Amstutz U, Shear NH, Rieder MJ, Hwang S, Fung V, Nakamura H, Connolly MB, Ito S, Carleton BC; CPNDS clinical recommendation group.

Epilepsia. 2014 Apr;55(4):496-506. doi: 10.1111/epi.12564. Epub 2014 Mar 5. Review.


Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.

Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, Flannick J, Zhang J, Fuchsberger C, Gaulton K, Lindgren C, Locke A, Manning A, Sim X, Rivas MA, Holmen OL, Gottesman O, Lu Y, Ruderfer D, Stahl EA, Duan Q, Li Y, Durda P, Jiao S, Isaacs A, Hofman A, Bis JC, Correa A, Griswold ME, Jakobsdottir J, Smith AV, Schreiner PJ, Feitosa MF, Zhang Q, Huffman JE, Crosby J, Wassel CL, Do R, Franceschini N, Martin LW, Robinson JG, Assimes TL, Crosslin DR, Rosenthal EA, Tsai M, Rieder MJ, Farlow DN, Folsom AR, Lumley T, Fox ER, Carlson CS, Peters U, Jackson RD, van Duijn CM, Uitterlinden AG, Levy D, Rotter JI, Taylor HA, Gudnason V Jr, Siscovick DS, Fornage M, Borecki IB, Hayward C, Rudan I, Chen YE, Bottinger EP, Loos RJ, Sætrom P, Hveem K, Boehnke M, Groop L, McCarthy M, Meitinger T, Ballantyne CM, Gabriel SB, O'Donnell CJ, Post WS, North KE, Reiner AP, Boerwinkle E, Psaty BM, Altshuler D, Kathiresan S, Lin DY, Jarvik GP, Cupples LA, Kooperberg C, Wilson JG, Nickerson DA, Abecasis GR, Rich SS, Tracy RP, Willer CJ; NHLBI Grand Opportunity Exome Sequencing Project.

Am J Hum Genet. 2014 Feb 6;94(2):233-45. doi: 10.1016/j.ajhg.2014.01.010.


Azithromycin use in paediatrics: A practical overview.

Ovetchkine P, Rieder MJ; Canadian Paediatric Society, Drug Therapy and Hazardous Substances Committee.

Paediatr Child Health. 2013 Jun;18(6):311-6. English, French.

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