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Circulating Endothelial Cells From Septic Shock Patients Convert to Fibroblasts Are Associated With the Resuscitation Fluid Dose and Are Biomarkers for Survival Prediction.

Tapia P, Gatica S, Cortés-Rivera C, Otero C, Becerra A, Riedel CA, Cabello-Verrugio C, Kalergis AM, Simon F.

Crit Care Med. 2019 Jul;47(7):942-950. doi: 10.1097/CCM.0000000000003778.


Correction: The ArcAB two-component regulatory system promotes resistance to reactive oxygen species and systemic infection by Salmonella Typhimurium.

Pardo-Esté C, Hidalgo AA, Aguirre C, Inostroza A, Briones AC, Cabezas CE, Castro-Severyn J, Fuentes JA, Opazo CM, Riedel CA, Otero C, Pacheco R, Valvano MA, Saavedra CP.

PLoS One. 2019 Mar 26;14(3):e0214634. doi: 10.1371/journal.pone.0214634. eCollection 2019.


Herpes Simplex Virus Type 1 Infection of the Central Nervous System: Insights Into Proposed Interrelationships With Neurodegenerative Disorders.

Duarte LF, Farías MA, Álvarez DM, Bueno SM, Riedel CA, González PA.

Front Cell Neurosci. 2019 Feb 26;13:46. doi: 10.3389/fncel.2019.00046. eCollection 2019. Review.


Copper deficiency-induced anemia is caused by a mitochondrial metabolic reprograming in erythropoietic cells.

Jensen EL, Gonzalez-Ibanez AM, Mendoza P, Ruiz LM, Riedel CA, Simon F, Schuringa JJ, Elorza AA.

Metallomics. 2019 Feb 20;11(2):282-290. doi: 10.1039/c8mt00224j.


Expanding the Current Knowledge About the Role of Interleukin-10 to Major Concerning Bacteria.

Peñaloza HF, Noguera LP, Riedel CA, Bueno SM.

Front Microbiol. 2018 Sep 18;9:2047. doi: 10.3389/fmicb.2018.02047. eCollection 2018. Review.


Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression.

Sebastián VP, Salazar GA, Coronado-Arrázola I, Schultz BM, Vallejos OP, Berkowitz L, Álvarez-Lobos MM, Riedel CA, Kalergis AM, Bueno SM.

Front Immunol. 2018 Sep 12;9:1956. doi: 10.3389/fimmu.2018.01956. eCollection 2018. Review.


The ArcAB two-component regulatory system promotes resistance to reactive oxygen species and systemic infection by Salmonella Typhimurium.

Pardo-Esté C, Hidalgo AA, Aguirre C, Briones AC, Cabezas CE, Castro-Severyn J, Fuentes JA, Opazo CM, Riedel CA, Otero C, Pacheco R, Valvano MA, Saavedra CP.

PLoS One. 2018 Sep 4;13(9):e0203497. doi: 10.1371/journal.pone.0203497. eCollection 2018. Erratum in: PLoS One. 2019 Mar 26;14(3):e0214634.


Role of Regulatory T Cells in Infection and Vaccination During Early Infancy.

Funes SC, Mansilla MA, Canedo-Marroquín G, Lay MK, Riedel CA, Kalergis AM.

Curr Pharm Des. 2018;24(30):3495-3505. doi: 10.2174/1381612824666180829094315.


Gestational Hypothyroxinemia Affects Its Offspring With a Reduced Suppressive Capacity Impairing the Outcome of the Experimental Autoimmune Encephalomyelitis.

Haensgen H, Albornoz E, Opazo MC, Bugueño K, Jara Fernández EL, Binzberger R, Rivero-Castillo T, Venegas Salas LF, Simon F, Cabello-Verrugio C, Elorza AA, Kalergis AM, Bueno SM, Riedel CA.

Front Immunol. 2018 Jun 6;9:1257. doi: 10.3389/fimmu.2018.01257. eCollection 2018.


Persistent Salmonella enterica serovar Typhimurium Infection Increases the Susceptibility of Mice to Develop Intestinal Inflammation.

Schultz BM, Salazar GA, Paduro CA, Pardo-Roa C, Pizarro DP, Salazar-Echegarai FJ, Torres J, Riedel CA, Kalergis AM, Álvarez-Lobos MM, Bueno SM.

Front Immunol. 2018 May 29;9:1166. doi: 10.3389/fimmu.2018.01166. eCollection 2018.


Role of Oxidative Stress as Key Regulator of Muscle Wasting during Cachexia.

Ábrigo J, Elorza AA, Riedel CA, Vilos C, Simon F, Cabrera D, Estrada L, Cabello-Verrugio C.

Oxid Med Cell Longev. 2018 Mar 28;2018:2063179. doi: 10.1155/2018/2063179. eCollection 2018. Review.


Intestinal Microbiota Influences Non-intestinal Related Autoimmune Diseases.

Opazo MC, Ortega-Rocha EM, Coronado-Arrázola I, Bonifaz LC, Boudin H, Neunlist M, Bueno SM, Kalergis AM, Riedel CA.

Front Microbiol. 2018 Mar 12;9:432. doi: 10.3389/fmicb.2018.00432. eCollection 2018. Review.


Evaluation of monoclonal antibodies that detect conserved proteins from Respiratory Syncytial Virus, Metapneumovirus and Adenovirus in human samples.

González LA, Vázquez Y, Mora JE, Palavecino CE, Bertrand P, Ferrés M, Contreras AM, Beckhaus AA, Riedel CA, Bueno SM.

J Virol Methods. 2018 Apr;254:51-64. doi: 10.1016/j.jviromet.2018.01.011. Epub 2018 Feb 1.


Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution.

Rey-Jurado E, Tapia F, Muñoz-Durango N, Lay MK, Carreño LJ, Riedel CA, Bueno SM, Genzel Y, Kalergis AM.

Front Immunol. 2018 Jan 18;9:26. doi: 10.3389/fimmu.2018.00026. eCollection 2018. Review.


Innate immune cells for immunotherapy of autoimmune and cancer disorders.

Schäfer C, Ascui G, Ribeiro CH, López M, Prados-Rosales R, González PA, Bueno SM, Riedel CA, Baena A, Kalergis AM, Carreño LJ.

Int Rev Immunol. 2017 Nov 2;36(6):315-337. doi: 10.1080/08830185.2017.1365145. Epub 2017 Sep 21. Review.


Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity.

Canedo-Marroquín G, Acevedo-Acevedo O, Rey-Jurado E, Saavedra JM, Lay MK, Bueno SM, Riedel CA, Kalergis AM.

Front Cell Infect Microbiol. 2017 Aug 16;7:367. doi: 10.3389/fcimb.2017.00367. eCollection 2017. Review.


Interleukin-10 Production by T and B Cells Is a Key Factor to Promote Systemic Salmonella enterica Serovar Typhimurium Infection in Mice.

Salazar GA, Peñaloza HF, Pardo-Roa C, Schultz BM, Muñoz-Durango N, Gómez RS, Salazar FJ, Pizarro DP, Riedel CA, González PA, Alvarez-Lobos M, Kalergis AM, Bueno SM.

Front Immunol. 2017 Aug 2;8:889. doi: 10.3389/fimmu.2017.00889. eCollection 2017.


Gestational Hypothyroxinemia Imprints a Switch in the Capacity of Astrocytes and Microglial Cells of the Offspring to React in Inflammation.

Opazo MC, González PA, Flores BD, Venegas LF, Albornoz EA, Cisternas P, Bohmwald K, Nieto PA, Bueno SM, Kalergis AM, Riedel CA.

Mol Neurobiol. 2018 May;55(5):4373-4387. doi: 10.1007/s12035-017-0627-y. Epub 2017 Jun 27.


Heme Oxygenase-1 Modulates Human Respiratory Syncytial Virus Replication and Lung Pathogenesis during Infection.

Espinoza JA, León MA, Céspedes PF, Gómez RS, Canedo-Marroquín G, Riquelme SA, Salazar-Echegarai FJ, Blancou P, Simon T, Anegon I, Lay MK, González PA, Riedel CA, Bueno SM, Kalergis AM.

J Immunol. 2017 Jul 1;199(1):212-223. doi: 10.4049/jimmunol.1601414. Epub 2017 May 31.


Nanoscale modeling of electro-plasmonic tunable devices for modulators and metasurfaces.

Riedel CA, Sun K, Muskens OL, de Groot CH.

Opt Express. 2017 May 1;25(9):10031-10043. doi: 10.1364/OE.25.010031.


A Potential Role of Salmonella Infection in the Onset of Inflammatory Bowel Diseases.

Schultz BM, Paduro CA, Salazar GA, Salazar-Echegarai FJ, Sebastián VP, Riedel CA, Kalergis AM, Alvarez-Lobos M, Bueno SM.

Front Immunol. 2017 Feb 28;8:191. doi: 10.3389/fimmu.2017.00191. eCollection 2017. Review.


Imprinting of maternal thyroid hormones in the offspring.

Opazo MC, Haensgen H, Bohmwald K, Venegas LF, Boudin H, Elorza AA, Simon F, Fardella C, Bueno SM, Kalergis AM, Riedel CA.

Int Rev Immunol. 2017 Jul 4;36(4):240-255. doi: 10.1080/08830185.2016.1277216. Epub 2017 Mar 8. Review.


Modulating the function of the immune system by thyroid hormones and thyrotropin.

Jara EL, Muñoz-Durango N, Llanos C, Fardella C, González PA, Bueno SM, Kalergis AM, Riedel CA.

Immunol Lett. 2017 Apr;184:76-83. doi: 10.1016/j.imlet.2017.02.010. Epub 2017 Feb 17. Review.


Aberrant T cell immunity triggered by human Respiratory Syncytial Virus and human Metapneumovirus infection.

González AE, Lay MK, Jara EL, Espinoza JA, Gómez RS, Soto J, Rivera CA, Abarca K, Bueno SM, Riedel CA, Kalergis AM.

Virulence. 2017 Aug 18;8(6):685-704. doi: 10.1080/21505594.2016.1265725. Epub 2016 Dec 2. Review.


Endothelial-to-mesenchymal transition: Cytokine-mediated pathways that determine endothelial fibrosis under inflammatory conditions.

Pérez L, Muñoz-Durango N, Riedel CA, Echeverría C, Kalergis AM, Cabello-Verrugio C, Simon F.

Cytokine Growth Factor Rev. 2017 Feb;33:41-54. doi: 10.1016/j.cytogfr.2016.09.002. Epub 2016 Sep 23. Review.


Hormonal Modulation of Dendritic Cells Differentiation, Maturation and Function: Implications for the Initiation and Progress of Systemic Autoimmunity.

Mackern-Oberti JP, Jara EL, Riedel CA, Kalergis AM.

Arch Immunol Ther Exp (Warsz). 2017 Apr;65(2):123-136. doi: 10.1007/s00005-016-0418-6. Epub 2016 Sep 1. Review.


Opposing roles of IL-10 in acute bacterial infection.

Peñaloza HF, Schultz BM, Nieto PA, Salazar GA, Suazo I, Gonzalez PA, Riedel CA, Alvarez-Lobos MM, Kalergis AM, Bueno SM.

Cytokine Growth Factor Rev. 2016 Dec;32:17-30. doi: 10.1016/j.cytogfr.2016.07.003. Epub 2016 Jul 25. Review.


Human Respiratory Syncytial Virus: Infection and Pathology.

Bohmwald K, Espinoza JA, Rey-Jurado E, Gómez RS, González PA, Bueno SM, Riedel CA, Kalergis AM.

Semin Respir Crit Care Med. 2016 Aug;37(4):522-37. doi: 10.1055/s-0036-1584799. Epub 2016 Aug 3. Review.


Gestational Hypothyroidism Improves the Ability of the Female Offspring to Clear Streptococcus pneumoniae Infection and to Recover From Pneumococcal Pneumonia.

Nieto PA, Peñaloza HF, Salazar-Echegarai FJ, Castellanos RM, Opazo MC, Venegas L, Padilla O, Kalergis AM, Riedel CA, Bueno SM.

Endocrinology. 2016 Jun;157(6):2217-28. doi: 10.1210/en.2015-1957. Epub 2016 Apr 1.


New insights about excisable pathogenicity islands in Salmonella and their contribution to virulence.

Nieto PA, Pardo-Roa C, Salazar-Echegarai FJ, Tobar HE, Coronado-Arrázola I, Riedel CA, Kalergis AM, Bueno SM.

Microbes Infect. 2016 May;18(5):302-9. doi: 10.1016/j.micinf.2016.02.001. Epub 2016 Mar 3. Review.


Modulation of antigen processing by haem-oxygenase 1. Implications on inflammation and tolerance.

Riquelme SA, Carreño LJ, Espinoza JA, Mackern-Oberti JP, Alvarez-Lobos MM, Riedel CA, Bueno SM, Kalergis AM.

Immunology. 2016 Sep;149(1):1-12. doi: 10.1111/imm.12605. Epub 2016 Apr 1. Review.


Gestational Hypothyroxinemia Affects Glutamatergic Synaptic Protein Distribution and Neuronal Plasticity Through Neuron-Astrocyte Interplay.

Cisternas P, Louveau A, Bueno SM, Kalergis AM, Boudin H, Riedel CA.

Mol Neurobiol. 2016 Dec;53(10):7158-7169. Epub 2015 Dec 19.


Understanding Lung Immunopathology Caused by the Human Metapneumovirus: Implications for Rational Vaccine Design.

Palavecino CE, Cespedes PF, Lay MK, Riedel CA, Kalergis AM, Bueno SM.

Crit Rev Immunol. 2015;35(3):185-202. Review.


Novel therapies and vaccines against the human respiratory syncytial virus.

Rivera CA, Gómez RS, Díaz RA, Céspedes PF, Espinoza JA, González PA, Riedel CA, Bueno SM, Kalergis AM.

Expert Opin Investig Drugs. 2015;24(12):1613-30. doi: 10.1517/13543784.2015.1099626. Epub 2015 Oct 12. Review.


Modulation of Immunity and Inflammation by the Mineralocorticoid Receptor and Aldosterone.

Muñoz-Durango N, Vecchiola A, Gonzalez-Gomez LM, Simon F, Riedel CA, Fardella CE, Kalergis AM.

Biomed Res Int. 2015;2015:652738. doi: 10.1155/2015/652738. Epub 2015 Sep 10. Review.


Contribution of autophagy to antiviral immunity.

Rey-Jurado E, Riedel CA, González PA, Bueno SM, Kalergis AM.

FEBS Lett. 2015 Nov 14;589(22):3461-70. doi: 10.1016/j.febslet.2015.07.047. Epub 2015 Aug 20. Review.


Contribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosus.

Mackern-Oberti JP, Llanos C, Riedel CA, Bueno SM, Kalergis AM.

Immunology. 2015 Dec;146(4):497-507. doi: 10.1111/imm.12504. Epub 2015 Oct 12. Review.


New insights on the viral and host factors contributing to the airway pathogenesis caused by the respiratory syncytial virus.

Lay MK, Bueno SM, Gálvez N, Riedel CA, Kalergis AM.

Crit Rev Microbiol. 2016 Sep;42(5):800-12. doi: 10.3109/1040841X.2015.1055711. Epub 2015 Jun 29. Review.


Interleukin-10 plays a key role in the modulation of neutrophils recruitment and lung inflammation during infection by Streptococcus pneumoniae.

Peñaloza HF, Nieto PA, Muñoz-Durango N, Salazar-Echegarai FJ, Torres J, Parga MJ, Alvarez-Lobos M, Riedel CA, Kalergis AM, Bueno SM.

Immunology. 2015 Sep;146(1):100-12. doi: 10.1111/imm.12486.


Inflammatory damage on respiratory and nervous systems due to hRSV infection.

Bohmwald K, Espinoza JA, Becerra D, Rivera K, Lay MK, Bueno SM, Riedel CA, Kalergis AM.

Curr Opin Immunol. 2015 Oct;36:14-21. doi: 10.1016/j.coi.2015.05.003. Epub 2015 May 27. Review.


Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species.

Arriagada AA, Albornoz E, Opazo MC, Becerra A, Vidal G, Fardella C, Michea L, Carrasco N, Simon F, Elorza AA, Bueno SM, Kalergis AM, Riedel CA.

Endocrinology. 2015 Apr;156(4):1540-51. doi: 10.1210/en.2014-1371. Epub 2015 Jan 16.


Modulation of host adaptive immunity by hRSV proteins.

Espinoza JA, Bohmwald K, Céspedes PF, Riedel CA, Bueno SM, Kalergis AM.

Virulence. 2014;5(7):740-51. doi: 10.4161/viru.32225. Review.


Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases.

Mackern-Oberti JP, Llanos C, Vega F, Salazar-Onfray F, Riedel CA, Bueno SM, Kalergis AM.

Autoimmun Rev. 2015 Feb;14(2):127-39. doi: 10.1016/j.autrev.2014.10.010. Epub 2014 Oct 14. Review.


The Expression of RAC1 and Mineralocorticoid Pathway-Dependent Genes are Associated With Different Responses to Salt Intake.

Tapia-Castillo A, Carvajal CA, Campino C, Hill C, Allende F, Vecchiola A, Carrasco C, Bancalari R, Valdivia C, Lagos C, Martinez-Aguayo A, Garcia H, Aglony M, Baudrand RF, Kalergis AM, Michea LF, Riedel CA, Fardella CE.

Am J Hypertens. 2015 Jun;28(6):722-8. doi: 10.1093/ajh/hpu224. Epub 2014 Nov 27.


Central nervous system alterations caused by infection with the human respiratory syncytial virus.

Bohmwald K, Espinoza JA, González PA, Bueno SM, Riedel CA, Kalergis AM.

Rev Med Virol. 2014 Nov;24(6):407-19. doi: 10.1002/rmv.1813. Epub 2014 Oct 14. Review.


Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells.

Céspedes PF, Bueno SM, Ramírez BA, Gomez RS, Riquelme SA, Palavecino CE, Mackern-Oberti JP, Mora JE, Depoil D, Sacristán C, Cammer M, Creneguy A, Nguyen TH, Riedel CA, Dustin ML, Kalergis AM.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):E3214-23. doi: 10.1073/pnas.1400760111. Epub 2014 Jul 23.


Induction of protective effector immunity to prevent pathogenesis caused by the respiratory syncytial virus. Implications on therapy and vaccine design.

Espinoza JA, Bueno SM, Riedel CA, Kalergis AM.

Immunology. 2014 Sep;143(1):1-12. doi: 10.1111/imm.12313. Review.


Heme oxygenase-1 as a target for the design of gene and pharmaceutical therapies for autoimmune diseases.

Mackern-Oberti JP, Riquelme SA, Llanos C, Schmidt CB, Simon T, Anegon I, Jara E, Riedel CA, Bueno SM, Kalergis AM.

Curr Gene Ther. 2014;14(3):218-35. Review.


Conjugal transfer of the pathogenicity island ROD21 in Salmonella enterica serovar Enteritidis depends on environmental conditions.

Salazar-Echegarai FJ, Tobar HE, Nieto PA, Riedel CA, Bueno SM.

PLoS One. 2014 Apr 4;9(4):e90626. doi: 10.1371/journal.pone.0090626. eCollection 2014.


Impaired spatial memory in mice lacking CD3ζ is associated with altered NMDA and AMPA receptors signaling independent of T-cell deficiency.

Louveau A, Angibaud J, Haspot F, Opazo MC, Thinard R, Thepenier V, Baudouin SJ, Lescaudron L, Hulin P, Riedel CA, Boudin H.

J Neurosci. 2013 Nov 20;33(47):18672-85. doi: 10.1523/JNEUROSCI.3028-13.2013.

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