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Items: 1 to 50 of 129

1.

Evaluation of artemisone combinations in Aotus monkeys infected with Plasmodium falciparum.

Obaldia N 3rd, Kotecka BM, Edstein MD, Haynes RK, Fugmann B, Kyle DE, Rieckmann KH.

Antimicrob Agents Chemother. 2009 Aug;53(8):3592-4. doi: 10.1128/AAC.00471-09. Epub 2009 Jun 8.

2.

First assessment in humans of the safety, tolerability, pharmacokinetics, and ex vivo pharmacodynamic antimalarial activity of the new artemisinin derivative artemisone.

Nagelschmitz J, Voith B, Wensing G, Roemer A, Fugmann B, Haynes RK, Kotecka BM, Rieckmann KH, Edstein MD.

Antimicrob Agents Chemother. 2008 Sep;52(9):3085-91. doi: 10.1128/AAC.01585-07. Epub 2008 Jun 16.

3.

Antimalarial pharmacodynamics and pharmacokinetics of a third-generation antifolate--JPC2056--in cynomolgus monkeys using an in vivo in vitro model.

Edstein MD, Kotecka BM, Ager AL, Smith KS, DiTusa CA, Diaz DS, Kyle DE, Schiehser GA, Jacobus DP, Rieckmann KH, O'Neil MT.

J Antimicrob Chemother. 2007 Oct;60(4):811-8. Epub 2007 Jul 23.

PMID:
17646199
4.

Vivax malaria: preliminary observations following a shorter course of treatment with artesunate plus primaquine.

Dao NV, Cuong BT, Ngoa ND, Thuy le TT, The ND, Duy DN, Dai B, Thanh NX, Chavchich M, Rieckmann KH, Edstein MD.

Trans R Soc Trop Med Hyg. 2007 Jun;101(6):534-9. Epub 2007 Mar 21.

PMID:
17368694
5.

The chequered history of malaria control: are new and better tools the ultimate answer?

Rieckmann KH.

Ann Trop Med Parasitol. 2006 Dec;100(8):647-62. Review.

PMID:
17227646
6.

Gender differences in gastrointestinal disturbances and plasma concentrations of tafenoquine in healthy volunteers after tafenoquine administration for post-exposure vivax malaria prophylaxis.

Edstein MD, Nasveld PE, Kocisko DA, Kitchener SJ, Gatton ML, Rieckmann KH.

Trans R Soc Trop Med Hyg. 2007 Mar;101(3):226-30. Epub 2006 Jun 30.

PMID:
16814823
7.

Does gender, food or grapefruit juice alter the pharmacokinetics of primaquine in healthy subjects?

Cuong BT, Binh VQ, Dai B, Duy DN, Lovell CM, Rieckmann KH, Edstein MD.

Br J Clin Pharmacol. 2006 Jun;61(6):682-9.

8.

Lengthy antimalarial activity of atovaquone in human plasma following atovaquone-proguanil administration.

Edstein MD, Kotecka BM, Anderson KL, Pombo DJ, Kyle DE, Rieckmann KH, Good MF.

Antimicrob Agents Chemother. 2005 Oct;49(10):4421-2. No abstract available.

9.

Fatty food does not alter blood mefloquine concentrations in the treatment of falciparum malaria.

Dao NV, Quoc NP, Ngoa ND, Thuy le T, The ND, Dai B, Binh VQ, Rieckmann KH, Edstein MD.

Trans R Soc Trop Med Hyg. 2005 Dec;99(12):927-31. Epub 2005 Sep 6.

PMID:
16143357
10.

Efficacy of monthly tafenoquine for prophylaxis of Plasmodium vivax and multidrug-resistant P. falciparum malaria.

Walsh DS, Eamsila C, Sasiprapha T, Sangkharomya S, Khaewsathien P, Supakalin P, Tang DB, Jarasrumgsichol P, Cherdchu C, Edstein MD, Rieckmann KH, Brewer TG.

J Infect Dis. 2004 Oct 15;190(8):1456-63. Epub 2004 Sep 20.

PMID:
15378438
11.
12.

Plasma concentrations of tafenoquine, a new long-acting antimalarial agent, in thai soldiers receiving monthly prophylaxis.

Edstein MD, Kocisko DA, Walsh DS, Eamsila C, Charles BG, Rieckmann KH.

Clin Infect Dis. 2003 Dec 15;37(12):1654-8. Epub 2003 Nov 20.

PMID:
14689348
13.

Comparison of bioassay and high performance liquid chromatographic assay of artesunate and dihydroartemisinin in plasma.

Kotecka BM, Rieckmann KH, Davis TM, Batty KT, Ilett KF.

Acta Trop. 2003 Aug;87(3):371-5.

PMID:
12875931
14.

New haplotypes of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene among chloroquine-resistant parasite isolates.

Nagesha HS, Casey GJ, Rieckmann KH, Fryauff DJ, Laksana BS, Reeder JC, Maguire JD, Baird JK.

Am J Trop Med Hyg. 2003 Apr;68(4):398-402.

PMID:
12875286
15.

Can primaquine therapy for vivax malaria be improved?

Baird JK, Rieckmann KH.

Trends Parasitol. 2003 Mar;19(3):115-20.

PMID:
12643993
16.

Simple in vitro assay for determining the sensitivity of Plasmodium vivax isolates from fresh human blood to antimalarials in areas where P. vivax is endemic.

Russell BM, Udomsangpetch R, Rieckmann KH, Kotecka BM, Coleman RE, Sattabongkot J.

Antimicrob Agents Chemother. 2003 Jan;47(1):170-3.

17.

Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.

Jensen NP, Ager AL, Bliss RA, Canfield CJ, Kotecka BM, Rieckmann KH, Terpinski J, Jacobus DP.

J Med Chem. 2001 Nov 8;44(23):3925-31.

PMID:
11689078
18.

Malaria prophylaxis/radical cure: recent experiences of the Australian Defence Force.

Edstein MD, Walsh DS, Eamsila C, Sasiprapha T, Nasveld PE, Kitchener S, Rieckmann KH.

Med Trop (Mars). 2001;61(1):56-8. Review.

PMID:
11584657
19.

Malaria in the Australian Defence Force during and after participation in the International Force in East Timor (INTERFET).

Kitchener SJ, Auliff AM, Rieckmann KH.

Med J Aust. 2000 Dec 4-18;173(11-12):583-5.

PMID:
11379495
20.

Indirect inhibition by antibiotics of nucleotide and deoxynucleotide biosynthesis in Plasmodium falciparum.

Yeo AE, Rieckmann KH, Christopherson RI.

Southeast Asian J Trop Med Public Health. 1998 Mar;29(1):24-6.

PMID:
9740262
21.

dCTP levels are maintained in Plasmodium falciparum subjected to pyrimidine deficiency or excess.

Seymour KK, Yeo AE, Rieckmann KH, Christopherson RI.

Ann Trop Med Parasitol. 1997 Sep;91(6):603-9.

PMID:
9425362
22.

In vitro activities of the biguanide PS-15 and its metabolite, WR99210, against cycloguanil-resistant Plasmodium falciparum isolates from Thailand.

Edstein MD, Bahr S, Kotecka B, Shanks GD, Rieckmann KH.

Antimicrob Agents Chemother. 1997 Oct;41(10):2300-1.

23.

Antimalaria activity of the triple combination of proguanil, atovaquone and dapsone.

Yeo AE, Edstein MD, Rieckmann KH.

Acta Trop. 1997 Sep 30;67(3):207-14.

PMID:
9241385
24.

Plasma chloroquine concentrations in young and older malaria patients treated with chloroquine.

Maitland K, Williams TN, Kotecka BM, Edstein MD, Rieckmann KH.

Acta Trop. 1997 Sep 10;66(3):155-61.

PMID:
9210966
25.

Ex vivo antimalarial activity of proguanil combined with dapsone against cycloguanil-resistant Plasmodium falciparum isolates.

Edstein MD, Yeo AE, Shanks GD, Rieckmann KH.

Acta Trop. 1997 Sep 10;66(3):127-35.

PMID:
9210963
26.

Anti-malarial drug resistance, malnutrition and socio-economic status.

Hess FI, Nukuro E, Judson L, Rodgers J, Nothdurft HD, Rieckmann KH.

Trop Med Int Health. 1997 Aug;2(8):721-8.

27.

New quinoline di-Mannich base compounds with greater antimalarial activity than chloroquine, amodiaquine, or pyronaridine.

Kotecka BM, Barlin GB, Edstein MD, Rieckmann KH.

Antimicrob Agents Chemother. 1997 Jun;41(6):1369-74.

28.

WR 238605, chloroquine, and their combinations as blood schizonticides against a chloroquine-resistant strain of Plasmodium vivax in Aotus monkeys.

Obaldia N 3rd, Rossan RN, Cooper RD, Kyle DE, Nuzum EO, Rieckmann KH, Shanks GD.

Am J Trop Med Hyg. 1997 May;56(5):508-10.

PMID:
9180599
29.

Disposition of proguanil in Thai patients with uncomplicated falciparum malaria.

Edstein MD, Looareesuwan S, Wilairatana P, Vanijanonta S, Kyle DE, Rieckmann KH.

Am J Trop Med Hyg. 1997 May;56(5):498-502.

PMID:
9180597
30.

Effects of dual combinations of antifolates with atovaquone or dapsone on nucleotide levels in Plasmodium falciparum.

Yeo AE, Seymour KK, Rieckmann KH, Christopherson RI.

Biochem Pharmacol. 1997 Apr 4;53(7):943-50.

PMID:
9174107
31.
32.

Potentiation of the antimalarial activity of atovaquone by doxycycline against Plasmodium falciparum in vitro.

Yeo AE, Edstein MD, Shanks GD, Rieckmann KH.

Parasitol Res. 1997;83(5):489-91.

PMID:
9197398
33.

Effects of folic and folinic acids in the activities of cycloguanil and WR99210 against Plasmodium falciparum in erythrocytic culture.

Yeo AE, Seymour KK, Rieckmann KH, Christopherson RI.

Ann Trop Med Parasitol. 1997 Jan;91(1):17-23.

PMID:
9093425
34.

Chloroquine bioassay of plasma specimens obtained from soldiers on chloroquine plus doxycycline for malaria prophylaxis.

Kotecka BM, Edstein MD, Rieckmann KH.

Int J Parasitol. 1996 Nov;26(11):1325-9.

PMID:
9024880
35.

Activity of PS-15 and its metabolite, WR99210, against Plasmodium falciparum in an in vivo-in vitro model.

Rieckmann KH, Yeo AE, Edstein MD.

Trans R Soc Trop Med Hyg. 1996 Sep-Oct;90(5):568-71.

PMID:
8944276
36.

Risk factors of chloroquine resistance in Plasmodium falciparum malaria.

Hess FI, Iannuzzi A, Leafasia J, Cowdrey D, Nothdurft HD, Von Sonnenburg F, Löscher T, Rieckmann KH.

Acta Trop. 1996 Aug;61(4):293-306.

PMID:
8910654
38.

Proguanil polymorphism does not affect the antimalarial activity of proguanil combined with atovaquone in vitro.

Edstein MD, Yeo AE, Kyle DE, Looareesuwan S, Wilairatana P, Rieckmann KH.

Trans R Soc Trop Med Hyg. 1996 Jul-Aug;90(4):418-21.

PMID:
8882194
39.

Immunochromatographic test for malaria diagnosis.

Garcia M, Kirimoama S, Marlborough D, Leafasia J, Rieckmann KH.

Lancet. 1996 Jun 1;347(9014):1549. No abstract available.

PMID:
8684115
40.

Doxycycline for malaria prophylaxis in Australian soldiers deployed to United Nations missions in Somalia and Cambodia.

Shanks GD, Roessler P, Edstein MD, Rieckmann KH.

Mil Med. 1995 Sep;160(9):443-5.

PMID:
7478027
41.
42.

Effectiveness of doxycycline combined with primaquine for malaria prophylaxis.

Shanks GD, Barnett A, Edstein MD, Rieckmann KH.

Med J Aust. 1995 Mar 20;162(6):306-7, 309-10.

PMID:
7715493
43.

In vivo-in vitro model to assess chloroquine activity in monkeys.

Kotecka BM, Rieckmann KH.

Chemotherapy. 1995 Mar-Apr;41(2):134-40.

PMID:
7758357
44.

A statistical analysis of the antimalarial activity of proguanil and cycloguanil in human volunteers.

Yeo AE, Edstein MD, Shanks GD, Rieckmann KH.

Ann Trop Med Parasitol. 1994 Dec;88(6):587-94.

PMID:
7893172
45.

The efficacy of WR238605 against the blood stages of a chloroquine resistant strain of Plasmodium vivax.

Cooper RD, Milhous WK, Rieckmann KH.

Trans R Soc Trop Med Hyg. 1994 Nov-Dec;88(6):691-2. No abstract available.

PMID:
7886774
46.

The activity of PS-15 in combination with sulfamethoxazole.

Yeo AE, Rieckmann KH.

Trop Med Parasitol. 1994 Jun;45(2):136-7.

PMID:
7939165
47.

Cytotoxic effects of inhibitors of de novo pyrimidine biosynthesis upon Plasmodium falciparum.

Seymour KK, Lyons SD, Phillips L, Rieckmann KH, Christopherson RI.

Biochemistry. 1994 May 3;33(17):5268-74.

PMID:
7909690
48.
49.

The in vitro antimalarial activity of chloramphenicol against Plasmodium falciparum.

Yeo AE, Rieckmann KH.

Acta Trop. 1994 Feb;56(1):51-4.

PMID:
8203295
50.

Evaluation of WR250417 (a proguanil analog) for causal prophylactic activity in the Plasmodium cynomolgi-Macaca mulatta model.

Edstein MD, Corcoran KD, Shanks GD, Ngampochjana M, Hansukjariya P, Sattabongkot J, Webster HK, Rieckmann KH.

Am J Trop Med Hyg. 1994 Feb;50(2):181-6.

PMID:
8116810

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