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Items: 49

1.

Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma.

Hossain JA, Latif MA, Ystaas LAR, Ninzima S, Riecken K, Muller A, Azuaje F, Joseph JV, Talasila KM, Ghimire J, Fehse B, Bjerkvig R, Miletic H.

Neuro Oncol. 2019 Apr 8. pii: noz060. doi: 10.1093/neuonc/noz060. [Epub ahead of print]

PMID:
30958558
2.

Dissecting hiPSC-CM pacemaker function in a cardiac organoid model.

Schulze ML, Lemoine MD, Fischer AW, Scherschel K, David R, Riecken K, Hansen A, Eschenhagen T, Ulmer BM.

Biomaterials. 2019 Jun;206:133-145. doi: 10.1016/j.biomaterials.2019.03.023. Epub 2019 Mar 21.

PMID:
30933775
3.

Nanobody Targeting of Epidermal Growth Factor Receptor (EGFR) Ectodomain Variants Overcomes Resistance to Therapeutic EGFR Antibodies.

Tintelnot J, Baum N, Schultheiß C, Braig F, Trentmann M, Finter J, Fumey W, Bannas P, Fehse B, Riecken K, Schuetze K, Bokemeyer C, Rösner T, Valerius T, Peipp M, Koch-Nolte F, Binder M.

Mol Cancer Ther. 2019 Apr;18(4):823-833. doi: 10.1158/1535-7163.MCT-18-0849. Epub 2019 Mar 1.

PMID:
30824613
4.

Cancer Suicide Gene Therapy with TK.007.

Hossain JA, Riecken K, Miletic H, Fehse B.

Methods Mol Biol. 2019;1895:11-26. doi: 10.1007/978-1-4939-8922-5_2.

PMID:
30539526
5.

Differential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Metastases.

Hänel L, Gosau T, Maar H, Valentiner U, Schumacher U, Riecken K, Windhorst S, Hansen NO, Heikaus L, Wurlitzer M, Nolte I, Schlüter H, Lange T.

Sci Rep. 2018 Sep 18;8(1):13986. doi: 10.1038/s41598-018-32236-1.

6.

Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks.

Brenière-Letuffe D, Domke-Shibamiya A, Hansen A, Eschenhagen T, Fehse B, Riecken K, Stenzig J.

Stem Cell Res Ther. 2018 Jun 18;9(1):165. doi: 10.1186/s13287-018-0893-2.

7.

In Vitro Model for Studying of the Role of IGFBP6 Gene in Breast Cancer Metastasizing.

Nikulin SV, Raigorodskaya MP, Poloznikov AA, Zakharova GS, Schumacher U, Wicklein D, Stürken C, Riecken K, Fomicheva KA, Alekseev BY, Shkurnikov MY.

Bull Exp Biol Med. 2018 Mar;164(5):688-692. doi: 10.1007/s10517-018-4060-7. Epub 2018 Mar 27.

PMID:
29582205
8.

Role of IGFBP6 Protein in the Regulation of Epithelial-Mesenchymal Transition Genes.

Nikulin SV, Raigorodskaya MP, Poloznikov AA, Zakharova GS, Schumacher U, Wicklein D, Stürken C, Riecken K, Fomicheva KA, Alekseev BY, Shkurnikov MY.

Bull Exp Biol Med. 2018 Mar;164(5):650-654. doi: 10.1007/s10517-018-4051-8. Epub 2018 Mar 26.

PMID:
29577195
9.

Locally Ablative Radiation Therapy of a Primary Human Small Cell Lung Cancer Tumor Decreases the Number of Spontaneous Metastases in Two Xenograft Models.

Frenzel T, Siekmann J, Grohmann C, Valentiner U, Schmitz R, Riecken K, Fehse B, Schumacher U, Lange T, Krüll A.

Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):1044-1056. doi: 10.1016/j.ijrobp.2017.11.044. Epub 2017 Dec 6.

PMID:
29485046
10.

The phosphotyrosine phosphatase SHP2 promotes anergy in chronic lymphocytic leukemia.

Schliffke S, Buhs S, Bolz S, Gerull H, von Wenserski L, Riecken K, Fehse B, Nollau P, Binder M.

Blood. 2018 Apr 12;131(15):1755-1758. doi: 10.1182/blood-2017-06-788166. Epub 2018 Feb 23. No abstract available.

11.

Knockdown of L1CAM significantly reduces metastasis in a xenograft model of human melanoma: L1CAM is a potential target for anti-melanoma therapy.

Ernst AK, Putscher A, Samatov TR, Suling A, Galatenko VV, Shkurnikov MY, Knyazev EN, Tonevitsky AG, Haalck T, Lange T, Maar H, Schröder-Schwarz J, Riecken K, Schumacher U, Wicklein D.

PLoS One. 2018 Feb 12;13(2):e0192525. doi: 10.1371/journal.pone.0192525. eCollection 2018.

12.

Multi-color RGB marking enables clonality assessment of liver tumors in a murine xenograft model.

Thomaschewski M, Riecken K, Unrau L, Volz T, Cornils K, Ittrich H, Heim D, Wege H, Akgün E, Lütgehetmann M, Dieckhoff J, Köpke M, Dandri M, Benten D, Fehse B.

Oncotarget. 2017 Dec 14;8(70):115582-115595. doi: 10.18632/oncotarget.23312. eCollection 2017 Dec 29.

13.

Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo.

Giersch K, Bhadra OD, Volz T, Allweiss L, Riecken K, Fehse B, Lohse AW, Petersen J, Sureau C, Urban S, Dandri M, Lütgehetmann M.

Gut. 2019 Jan;68(1):150-157. doi: 10.1136/gutjnl-2017-314713. Epub 2017 Dec 7.

PMID:
29217749
14.

Efficient gene editing via non-viral delivery of CRISPR-Cas9 system using polymeric and hybrid microcarriers.

Timin AS, Muslimov AR, Lepik KV, Epifanovskaya OS, Shakirova AI, Mock U, Riecken K, Okilova MV, Sergeev VS, Afanasyev BV, Fehse B, Sukhorukov GB.

Nanomedicine. 2018 Jan;14(1):97-108. doi: 10.1016/j.nano.2017.09.001. Epub 2017 Sep 14.

PMID:
28917642
15.

CHO cells engineered for fluorescence read out of cell cycle and growth rate in real time.

Fuge G, Hong Y, Riecken K, Zeng AP, Jandt U.

Biotechnol Prog. 2017 Sep;33(5):1408-1417. doi: 10.1002/btpr.2491. Epub 2017 May 28.

PMID:
28470866
16.

Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity.

Mohme M, Maire CL, Riecken K, Zapf S, Aranyossy T, Westphal M, Lamszus K, Fehse B.

Mol Ther. 2017 Mar 1;25(3):621-633. doi: 10.1016/j.ymthe.2016.12.014. Epub 2017 Jan 18.

17.

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain.

Askew K, Li K, Olmos-Alonso A, Garcia-Moreno F, Liang Y, Richardson P, Tipton T, Chapman MA, Riecken K, Beccari S, Sierra A, Molnár Z, Cragg MS, Garaschuk O, Perry VH, Gomez-Nicola D.

Cell Rep. 2017 Jan 10;18(2):391-405. doi: 10.1016/j.celrep.2016.12.041.

18.

Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism.

Braig F, Kriegs M, Voigtlaender M, Habel B, Grob T, Biskup K, Blanchard V, Sack M, Thalhammer A, Ben Batalla I, Braren I, Laban S, Danielczyk A, Goletz S, Jakubowicz E, Märkl B, Trepel M, Knecht R, Riecken K, Fehse B, Loges S, Bokemeyer C, Binder M.

Cancer Res. 2017 Mar 1;77(5):1188-1199. doi: 10.1158/0008-5472.CAN-16-0754. Epub 2016 Dec 28.

19.

Complementarity determining region-independent recognition of a superantigen by B-cell antigen receptors of mantle cell lymphoma.

Fichtner M, Spies E, Seismann H, Riecken K, Engels N, Gösch B, Dierlamm J, Gerull H, Nollau P, Klapper W, Dreyling M, Binder M, Trepel M.

Haematologica. 2016 Sep;101(9):e378-81. doi: 10.3324/haematol.2016.141929. No abstract available.

20.

Lentiviral HSV-Tk.007-mediated suicide gene therapy is not toxic for normal brain cells.

Hossain JA, Ystaas LR, Mrdalj J, Välk K, Riecken K, Fehse B, Bjerkvig R, Grønli J, Miletic H.

J Gene Med. 2016 Sep;18(9):234-43. doi: 10.1002/jgm.2895.

PMID:
27490042
21.

Investigation of the Mesenchymal Stem Cell Compartment by Means of a Lentiviral Barcode Library.

Bigildeev AE, Cornils K, Aranyossy T, Sats NV, Petinati NA, Shipounova IN, Surin VL, Pshenichnikova OS, Riecken K, Fehse B, Drize NI.

Biochemistry (Mosc). 2016 Apr;81(4):373-81. doi: 10.1134/S0006297916040076.

22.

Long-term in vivo single-cell tracking reveals the switch of migration patterns in adult-born juxtaglomerular cells of the mouse olfactory bulb.

Liang Y, Li K, Riecken K, Maslyukov A, Gomez-Nicola D, Kovalchuk Y, Fehse B, Garaschuk O.

Cell Res. 2016 Jul;26(7):805-21. doi: 10.1038/cr.2016.55. Epub 2016 May 13.

23.

Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer.

Bierwolf J, Volz T, Lütgehetmann M, Allweiss L, Riecken K, Warlich M, Fehse B, Kalff JC, Dandri M, Pollok JM.

Tissue Eng Part A. 2016 May;22(9-10):742-53. doi: 10.1089/ten.TEA.2015.0427.

24.

Microglia regulate hippocampal neurogenesis during chronic neurodegeneration.

De Lucia C, Rinchon A, Olmos-Alonso A, Riecken K, Fehse B, Boche D, Perry VH, Gomez-Nicola D.

Brain Behav Immun. 2016 Jul;55:179-190. doi: 10.1016/j.bbi.2015.11.001. Epub 2015 Nov 2.

25.

Combined Application of RGB Marking and Mass Spectrometric Imaging Facilitates Detection of Tumor Heterogeneity.

Abramowski P, Kraus O, Rohn S, Riecken K, Fehse B, Schlüter H.

Cancer Genomics Proteomics. 2015 Jul-Aug;12(4):179-87.

PMID:
26136218
26.

Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion.

Lin YN, Bhuwania R, Gromova K, Failla AV, Lange T, Riecken K, Linder S, Kneussel M, Izbicki JR, Windhorst S.

Oncotarget. 2015 Jul 30;6(21):18577-89.

27.

Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer.

Braig F, März M, Schieferdecker A, Schulte A, Voigt M, Stein A, Grob T, Alawi M, Indenbirken D, Kriegs M, Engel E, Vanhoefer U, Grundhoff A, Loges S, Riecken K, Fehse B, Bokemeyer C, Binder M.

Oncotarget. 2015 May 20;6(14):12035-47.

28.

Multicolor RGB Marking Allows Morphometric and Functional Analysis of Hippocampal Granule Neurons at the Single-Cell Level.

Gomez-Nicola D, Riecken K, Perry VH, Fehse B.

Hum Gene Ther. 2015 Jun;26(6):332-3. doi: 10.1089/hum.2015.010. Epub 2015 Apr 20.

29.

Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs.

Ben-Batalla I, Cubas-Cordova M, Udonta F, Wroblewski M, Waizenegger JS, Janning M, Sawall S, Gensch V, Zhao L, Martinez-Zubiaurre I, Riecken K, Fehse B, Pantel K, Bokemeyer C, Loges S.

Oncotarget. 2015 Mar 20;6(8):6341-58.

30.

Targeting species D adenoviruses replication to counteract the epidemic keratoconjunctivitis.

Nikitenko NA, Speiseder T, Groitl P, Spirin PV, Prokofjeva MM, Lebedev TD, Rubtsov PM, Lam E, Riecken K, Fehse B, Dobner T, Prassolov VS.

Biochimie. 2015 Jun;113:10-6. doi: 10.1016/j.biochi.2015.03.010. Epub 2015 Mar 19. Erratum in: Biochimie. 2015 Sep;116:166.

PMID:
25796214
31.

Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.

Wellbrock J, Latuske E, Köhler J, Wagner K, Stamm H, Vettorazzi E, Vohwinkel G, Klokow M, Uibeleisen R, Ehm P, Riecken K, Loges S, Thol F, Schubert C, Amling M, Jücker M, Bokemeyer C, Heuser M, Krauter J, Fiedler W.

Clin Cancer Res. 2015 May 15;21(10):2388-98. doi: 10.1158/1078-0432.CCR-14-1059. Epub 2015 Mar 5.

32.

Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen.

Michaelis M, Agha B, Rothweiler F, Löschmann N, Voges Y, Mittelbronn M, Starzetz T, Harter PN, Abhari BA, Fulda S, Westermann F, Riecken K, Spek S, Langer K, Wiese M, Dirks WG, Zehner R, Cinatl J, Wass MN, Cinatl J Jr.

Sci Rep. 2015 Feb 3;5:8202. doi: 10.1038/srep08202.

33.

In-vivo RGB marking and multicolour single-cell tracking in the adult brain.

Gomez-Nicola D, Riecken K, Fehse B, Perry VH.

Sci Rep. 2014 Dec 22;4:7520. doi: 10.1038/srep07520.

34.

Neural stem cell-based intraocular administration of ciliary neurotrophic factor attenuates the loss of axotomized ganglion cells in adult mice.

Flachsbarth K, Kruszewski K, Jung G, Jankowiak W, Riecken K, Wagenfeld L, Richard G, Fehse B, Bartsch U.

Invest Ophthalmol Vis Sci. 2014 Sep 30;55(11):7029-39. doi: 10.1167/iovs.14-15266.

PMID:
25270193
35.

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases.

Mock U, Riecken K, Berdien B, Qasim W, Chan E, Cathomen T, Fehse B.

Sci Rep. 2014 Sep 18;4:6409. doi: 10.1038/srep06409.

36.

Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL.

Schieferdecker A, Voigt M, Riecken K, Braig F, Schinke T, Loges S, Bokemeyer C, Fehse B, Binder M.

Oncotarget. 2014 Aug 30;5(16):6647-53.

37.

Role of Growth arrest-specific gene 6-Mer axis in multiple myeloma.

Waizenegger JS, Ben-Batalla I, Weinhold N, Meissner T, Wroblewski M, Janning M, Riecken K, Binder M, Atanackovic D, Taipaleenmaeki H, Schewe D, Sawall S, Gensch V, Cubas-Cordova M, Seckinger A, Fiedler W, Hesse E, Kröger N, Fehse B, Hose D, Klein B, Raab MS, Pantel K, Bokemeyer C, Loges S.

Leukemia. 2015 Mar;29(3):696-704. doi: 10.1038/leu.2014.236. Epub 2014 Aug 8.

PMID:
25102945
38.

Temporal dynamics of hippocampal neurogenesis in chronic neurodegeneration.

Gomez-Nicola D, Suzzi S, Vargas-Caballero M, Fransen NL, Al-Malki H, Cebrian-Silla A, Garcia-Verdugo JM, Riecken K, Fehse B, Perry VH.

Brain. 2014 Aug;137(Pt 8):2312-28. doi: 10.1093/brain/awu155. Epub 2014 Jun 18.

39.

Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism.

Oehler N, Volz T, Bhadra OD, Kah J, Allweiss L, Giersch K, Bierwolf J, Riecken K, Pollok JM, Lohse AW, Fehse B, Petersen J, Urban S, Lütgehetmann M, Heeren J, Dandri M.

Hepatology. 2014 Nov;60(5):1483-93. doi: 10.1002/hep.27159. Epub 2014 May 19.

PMID:
24711282
40.

Selectins mediate small cell lung cancer systemic metastasis.

Heidemann F, Schildt A, Schmid K, Bruns OT, Riecken K, Jung C, Ittrich H, Wicklein D, Reimer R, Fehse B, Heeren J, Lüers G, Schumacher U, Heine M.

PLoS One. 2014 Apr 3;9(4):e92327. doi: 10.1371/journal.pone.0092327. eCollection 2014.

41.

Cell adhesion molecules in metastatic neuroblastoma models.

Schwankhaus N, Gathmann C, Wicklein D, Riecken K, Schumacher U, Valentiner U.

Clin Exp Metastasis. 2014 Apr;31(4):483-96. doi: 10.1007/s10585-014-9643-8. Epub 2014 Feb 19.

PMID:
24549749
42.

Multiplexing clonality: combining RGB marking and genetic barcoding.

Cornils K, Thielecke L, Hüser S, Forgber M, Thomaschewski M, Kleist N, Hussein K, Riecken K, Volz T, Gerdes S, Glauche I, Dahl A, Dandri M, Roeder I, Fehse B.

Nucleic Acids Res. 2014 Apr;42(7):e56. doi: 10.1093/nar/gku081. Epub 2014 Jan 29.

43.

Testing of SNS-032 in a Panel of Human Neuroblastoma Cell Lines with Acquired Resistance to a Broad Range of Drugs.

Löschmann N, Michaelis M, Rothweiler F, Zehner R, Cinatl J, Voges Y, Sharifi M, Riecken K, Meyer J, von Deimling A, Fichtner I, Ghafourian T, Westermann F, Cinatl J Jr.

Transl Oncol. 2013 Dec 1;6(6):685-96. eCollection 2013 Dec 1.

44.

Genetically modified neural stem cells for a local and sustained delivery of neuroprotective factors to the dystrophic mouse retina.

Jung G, Sun J, Petrowitz B, Riecken K, Kruszewski K, Jankowiak W, Kunst F, Skevas C, Richard G, Fehse B, Bartsch U.

Stem Cells Transl Med. 2013 Dec;2(12):1001-10. doi: 10.5966/sctm.2013-0013. Epub 2013 Oct 28.

45.

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma.

Ben-Batalla I, Schultze A, Wroblewski M, Erdmann R, Heuser M, Waizenegger JS, Riecken K, Binder M, Schewe D, Sawall S, Witzke V, Cubas-Cordova M, Janning M, Wellbrock J, Fehse B, Hagel C, Krauter J, Ganser A, Lorens JB, Fiedler W, Carmeliet P, Pantel K, Bokemeyer C, Loges S.

Blood. 2013 Oct 3;122(14):2443-52. doi: 10.1182/blood-2013-03-491431. Epub 2013 Aug 27.

46.

A new system for parallel drug screening against multiple-resistant HIV mutants based on lentiviral self-inactivating (SIN) vectors and multi-colour analyses.

Prokofjeva MM, Riecken K, Spirin PV, Yanvarév DV, Düsedau A, Ellinger B, Fehse B, Stocking C, Prassolov VS.

AIDS Res Ther. 2013 Jan 3;10(1):1. doi: 10.1186/1742-6405-10-1.

47.

SOCS3 promotes interleukin-17 expression of human T cells.

Kleinsteuber K, Heesch K, Schattling S, Sander-Juelch C, Mock U, Riecken K, Fehse B, Fleischer B, Jacobsen M.

Blood. 2012 Nov 22;120(22):4374-82. doi: 10.1182/blood-2011-11-392738. Epub 2012 Oct 1.

48.

Comparative clonal analysis of reconstitution kinetics after transplantation of hematopoietic stem cells gene marked with a lentiviral SIN or a γ-retroviral LTR vector.

Cornils K, Bartholomae CC, Thielecke L, Lange C, Arens A, Glauche I, Mock U, Riecken K, Gerdes S, von Kalle C, Schmidt M, Roeder I, Fehse B.

Exp Hematol. 2013 Jan;41(1):28-38.e3. doi: 10.1016/j.exphem.2012.09.003. Epub 2012 Sep 16.

PMID:
22989760
49.

Absence of macrophage and presence of plasmacellular iron storage in the terminal duodenum of patients with hereditary haemochromatosis.

Düllmann J, Wulfhekel U, Mohr A, Riecken K, Hausmann K.

Virchows Arch A Pathol Anat Histopathol. 1991;418(3):241-7.

PMID:
1900970

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