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Items: 1 to 50 of 115

1.

Local release of tacrolimus from hydrogel-based drug delivery system is controlled by inflammatory enzymes in vivo and can be monitored non-invasively using in vivo imaging.

Dzhonova D, Olariu R, Leckenby J, Dhayani A, Vemula PK, Prost JC, Banz Y, Taddeo A, Rieben R.

PLoS One. 2018 Aug 30;13(8):e0203409. doi: 10.1371/journal.pone.0203409. eCollection 2018.

2.

Novel targeted drug delivery systems to minimize systemic immunosuppression in vascularized composite allotransplantation.

Taddeo A, Tsai C, Vögelin E, Rieben R.

Curr Opin Organ Transplant. 2018 Oct;23(5):568-576. doi: 10.1097/MOT.0000000000000564.

PMID:
30074507
3.

Local Injections of Tacrolimus-loaded Hydrogel Reduce Systemic Immunosuppression-related Toxicity in Vascularized Composite Allotransplantation.

Dzhonova DV, Olariu R, Leckenby J, Banz Y, Prost JC, Dhayani A, Vemula PK, Voegelin E, Taddeo A, Rieben R.

Transplantation. 2018 Oct;102(10):1684-1694. doi: 10.1097/TP.0000000000002283.

4.

Perfusion-decellularization of human ear grafts enables ECM-based scaffolds for auricular vascularized composite tissue engineering.

Duisit J, Amiel H, Wüthrich T, Taddeo A, Dedriche A, Destoop V, Pardoen T, Bouzin C, Joris V, Magee D, Vögelin E, Harriman D, Dessy C, Orlando G, Behets C, Rieben R, Gianello P, Lengelé B.

Acta Biomater. 2018 Jun;73:339-354. doi: 10.1016/j.actbio.2018.04.009. Epub 2018 Apr 11.

5.

3D artificial round section micro-vessels to investigate endothelial cells under physiological flow conditions.

Sfriso R, Zhang S, Bichsel CA, Steck O, Despont A, Guenat OT, Rieben R.

Sci Rep. 2018 Apr 12;8(1):5898. doi: 10.1038/s41598-018-24273-7.

6.

Improvement of a Closed Chest Porcine Myocardial Infarction Model by Standardization of Tissue and Blood Sampling Procedures.

Abdelhafez MM, Shaw J, Wilbs J, Despont A, Rieben R.

J Vis Exp. 2018 Mar 12;(133). doi: 10.3791/56856.

PMID:
29578502
7.

Multiple genetically modified GTKO/hCD46/HLA-E/hβ2-mg porcine hearts are protected from complement activation and natural killer cell infiltration during ex vivo perfusion with human blood.

Abicht JM, Sfriso R, Reichart B, Längin M, Gahle K, Puga Yung GL, Seebach JD, Rieben R, Ayares D, Wolf E, Klymiuk N, Baehr A, Kind A, Mayr T, Bauer A.

Xenotransplantation. 2018 Sep;25(5):e12390. doi: 10.1111/xen.12390. Epub 2018 Mar 14.

PMID:
29536572
8.

Type II Minimal-Invasive Extracorporeal Circuit for Aortic Valve Replacement: A Randomized Controlled Trial.

Gygax E, Kaeser HU, Stalder M, Gahl B, Rieben R, Carrel T, Erdoes G.

Artif Organs. 2018 Jun;42(6):620-629. doi: 10.1111/aor.13093. Epub 2018 Feb 12.

PMID:
29435996
9.

Effects of C1 inhibitor on endothelial cell activation in a rat hind limb ischemia-reperfusion injury model.

Zhang S, Shaw-Boden J, Banz Y, Bongoni AK, Taddeo A, Spirig R, Nolte MW, Cowan PJ, Rieben R.

J Vasc Surg. 2018 Jan 27. pii: S0741-5214(17)32653-8. doi: 10.1016/j.jvs.2017.10.072. [Epub ahead of print]

PMID:
29395422
10.

Release of pig leukocytes and reduced human NK cell recruitment during ex vivo perfusion of HLA-E/human CD46 double-transgenic pig limbs with human blood.

Puga Yung G, Bongoni AK, Pradier A, Madelon N, Papaserafeim M, Sfriso R, Ayares DL, Wolf E, Klymiuk N, Bähr A, Constantinescu MA, Voegelin E, Kiermeir D, Jenni H, Rieben R, Seebach JD.

Xenotransplantation. 2018 Jan;25(1). doi: 10.1111/xen.12357. Epub 2017 Oct 22.

PMID:
29057510
11.

Intra-graft injection of tacrolimus promotes survival of vascularized composite allotransplantation.

Olariu R, Denoyelle J, Leclère FM, Dzhonova DV, Gajanayake T, Banz Y, Hayoz M, Constantinescu M, Rieben R, Vögelin E, Taddeo A.

J Surg Res. 2017 Oct;218:49-57. doi: 10.1016/j.jss.2017.05.046. Epub 2017 Jun 10.

PMID:
28985877
12.

Assessment of the Anticoagulant and Anti-inflammatory Properties of Endothelial Cells Using 3D Cell Culture and Non-anticoagulated Whole Blood.

Sfriso R, Bongoni A, Banz Y, Klymiuk N, Wolf E, Rieben R.

J Vis Exp. 2017 Sep 5;(127). doi: 10.3791/56227.

PMID:
28930996
13.

Bioengineering a Human Face Graft: The Matrix of Identity.

Duisit J, Maistriaux L, Taddeo A, Orlando G, Joris V, Coche E, Behets C, Lerut J, Dessy C, Cossu G, Vögelin E, Rieben R, Gianello P, Lengelé B.

Ann Surg. 2017 Nov;266(5):754-764. doi: 10.1097/SLA.0000000000002396.

14.

Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood.

Bongoni AK, Salvaris E, Nordling S, Klymiuk N, Wolf E, Ayares DL, Rieben R, Magnusson PU, Cowan PJ.

Sci Rep. 2017 Jun 30;7(1):4450. doi: 10.1038/s41598-017-04898-w.

15.

Effect of C1-INH on ischemia/reperfusion injury in a porcine limb ex vivo perfusion model.

Abdelhafez MM, Shaw J, Sutter D, Schnider J, Banz Y, Jenni H, Voegelin E, Constantinescu MA, Rieben R.

Mol Immunol. 2017 Aug;88:116-124. doi: 10.1016/j.molimm.2017.06.021. Epub 2017 Jun 20.

PMID:
28641140
16.

Xenotransplantation: Where do we stand in 2016?

Puga Yung GL, Rieben R, Bühler L, Schuurman HJ, Seebach J.

Swiss Med Wkly. 2017 Feb 9;147:w14403. doi: 10.4414/smw.2017.14403. eCollection 2017. Review.

17.

Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function.

Pischke SE, Gustavsen A, Orrem HL, Egge KH, Courivaud F, Fontenelle H, Despont A, Bongoni AK, Rieben R, Tønnessen TI, Nunn MA, Scott H, Skulstad H, Barratt-Due A, Mollnes TE.

Basic Res Cardiol. 2017 May;112(3):20. doi: 10.1007/s00395-017-0610-9. Epub 2017 Mar 3.

18.

Role of the plasma cascade systems in ischemia/reperfusion injury of bone.

Zhang S, Wotzkow C, Bongoni AK, Shaw-Boden J, Siegrist M, Taddeo A, Blank F, Hofstetter W, Rieben R.

Bone. 2017 Apr;97:278-286. doi: 10.1016/j.bone.2016.12.007. Epub 2017 Jan 31.

PMID:
28159709
19.

Dexrazoxane Shows No Protective Effect in the Acute Phase of Reperfusion during Myocardial Infarction in Pigs.

Kamat P, Vandenberghe S, Christen S, Bongoni AK, Meier B, Rieben R, Khattab AA.

PLoS One. 2016 Dec 21;11(12):e0168541. doi: 10.1371/journal.pone.0168541. eCollection 2016.

20.

Vitreal Cytokine Profile Differences Between Eyes With Epiretinal Membranes or Macular Holes.

Zandi S, Tappeiner C, Pfister IB, Despont A, Rieben R, Garweg JG.

Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):6320-6326. doi: 10.1167/iovs.16-20657.

PMID:
27893098
21.

Correlation Between Sonographic and In Vivo Measurement of A1 Pulleys in Trigger Fingers.

Spirig A, Juon B, Banz Y, Rieben R, Vögelin E.

Ultrasound Med Biol. 2016 Jul;42(7):1482-90. doi: 10.1016/j.ultrasmedbio.2016.02.017. Epub 2016 Apr 26.

PMID:
27126241
22.

Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation.

Bongoni AK, Klymiuk N, Wolf E, Ayares D, Rieben R, Cowan PJ.

Transplantation. 2016 Sep;100(9):1871-9. doi: 10.1097/TP.0000000000001188.

23.

Higher macrophage superoxide anion production in coronary artery disease (CAD) patients with Type D personality.

Zuccarella-Hackl C, von Känel R, Thomas L, Kuebler P, Schmid JP, Mattle HP, Mono ML, Rieben R, Wiest R, Wirtz PH.

Psychoneuroendocrinology. 2016 Jun;68:186-93. doi: 10.1016/j.psyneuen.2016.02.031. Epub 2016 Mar 2.

PMID:
26994482
24.

Modifying the Glycome in Pigs for Xenotransplantation.

Cowan PJ, Rieben R.

Transplantation. 2016 Mar;100(3):485-6. doi: 10.1097/TP.0000000000001073. No abstract available.

25.

Endothelial- and Platelet-Derived Microparticles Are Generated During Liver Resection in Humans.

Banz Y, Item GM, Vogt A, Rieben R, Candinas D, Beldi G.

J Invest Surg. 2016;29(1):20-31. doi: 10.3109/08941939.2015.1047540. Epub 2015 Sep 16.

PMID:
26375814
26.

Inhalation anesthesia of rats: influence of the fraction of inspired oxygen on limb ischemia/reperfusion injury.

Zhang S, Duehrkop C, Plock JA, Rieben R.

Lab Anim. 2016 Jun;50(3):185-97. doi: 10.1177/0023677215604531. Epub 2015 Sep 7.

PMID:
26345513
27.

Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions.

Bongoni AK, Kiermeir D, Schnider J, Jenni H, Garimella P, Bähr A, Klymiuk N, Wolf E, Ayares D, Voegelin E, Constantinescu MA, Seebach JD, Rieben R.

Transplantation. 2015 Oct;99(10):2061-9. doi: 10.1097/TP.0000000000000746.

PMID:
25965410
28.

Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14.

Egge KH, Thorgersen EB, Pischke SE, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn MA, Barratt-Due A, Mollnes TE.

Immunobiology. 2015 Aug;220(8):999-1005. doi: 10.1016/j.imbio.2015.04.002. Epub 2015 Apr 27.

PMID:
25956456
29.

siRNA mediated knockdown of tissue factor expression in pigs for xenotransplantation.

Ahrens HE, Petersen B, Herrmann D, Lucas-Hahn A, Hassel P, Ziegler M, Kues WA, Baulain U, Baars W, Schwinzer R, Denner J, Rataj D, Werwitzke S, Tiede A, Bongoni AK, Garimella PS, Despont A, Rieben R, Niemann H.

Am J Transplant. 2015 May;15(5):1407-14. doi: 10.1111/ajt.13120. Epub 2015 Mar 23.

30.

Porcine extrahepatic vascular endothelial asialoglycoprotein receptor 1 mediates xenogeneic platelet phagocytosis in vitro and in human-to-pig ex vivo xenoperfusion.

Bongoni AK, Kiermeir D, Denoyelle J, Jenni H, Burlak C, Seebach JD, Vögelin E, Constantinescu MA, Rieben R.

Transplantation. 2015 Apr;99(4):693-701. doi: 10.1097/TP.0000000000000553.

31.

A single localized dose of enzyme-responsive hydrogel improves long-term survival of a vascularized composite allograft.

Gajanayake T, Olariu R, Leclère FM, Dhayani A, Yang Z, Bongoni AK, Banz Y, Constantinescu MA, Karp JM, Vemula PK, Rieben R, Vögelin E.

Sci Transl Med. 2014 Aug 13;6(249):249ra110. doi: 10.1126/scitranslmed.3008778.

32.

Complement dependent early immunological responses during ex vivo xenoperfusion of hCD46/HLA-E double transgenic pig forelimbs with human blood.

Bongoni AK, Kiermeir D, Jenni H, Bähr A, Ayares D, Klymiuk N, Wolf E, Voegelin E, Constantinescu MA, Seebach JD, Rieben R.

Xenotransplantation. 2014 May-Jun;21(3):230-43. doi: 10.1111/xen.12090. Epub 2014 Mar 17.

PMID:
24635052
33.

Refinement of tourniquet-induced peripheral ischemia/reperfusion injury in rats: comparison of 2 h vs 24 h reperfusion.

Duehrkop C, Rieben R.

Lab Anim. 2014 Apr;48(2):143-54. doi: 10.1177/0023677213516313.

PMID:
24585935
34.

Ischemia/reperfusion injury: effect of simultaneous inhibition of plasma cascade systems versus specific complement inhibition.

Duehrkop C, Rieben R.

Biochem Pharmacol. 2014 Mar 1;88(1):12-22. doi: 10.1016/j.bcp.2013.12.013. Epub 2013 Dec 30. Review.

PMID:
24384116
35.

Use of dextran sulfate in tourniquet-induced skeletal muscle reperfusion injury.

Duehrkop C, Denoyelle J, Shaw S, Rieben R.

J Surg Res. 2014 Mar;187(1):150-61. doi: 10.1016/j.jss.2013.10.012. Epub 2013 Oct 12.

PMID:
24176204
36.

Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs.

Wuensch A, Baehr A, Bongoni AK, Kemter E, Blutke A, Baars W, Haertle S, Zakhartchenko V, Kurome M, Kessler B, Faber C, Abicht JM, Reichart B, Wanke R, Schwinzer R, Nagashima H, Rieben R, Ayares D, Wolf E, Klymiuk N.

Transplantation. 2014 Jan 27;97(2):138-47. doi: 10.1097/TP.0b013e3182a95cbc.

37.

C1 esterase inhibitor reduces lower extremity ischemia/reperfusion injury and associated lung damage.

Duehrkop C, Banz Y, Spirig R, Miescher S, Nolte MW, Spycher M, Smith RA, Sacks SH, Rieben R.

PLoS One. 2013 Aug 26;8(8):e72059. doi: 10.1371/journal.pone.0072059. eCollection 2013.

38.

Reconstituted high-density lipoprotein modulates activation of human leukocytes.

Spirig R, Schaub A, Kropf A, Miescher S, Spycher MO, Rieben R.

PLoS One. 2013 Aug 14;8(8):e71235. doi: 10.1371/journal.pone.0071235. eCollection 2013.

39.

Activation of the lectin pathway of complement in pig-to-human xenotransplantation models.

Bongoni AK, Kiermeir D, Jenni H, Wünsch A, Bähr A, Ayares D, Seebach JD, Wolf E, Klymiuk N, Constantinescu MA, Vögelin E, Rieben R.

Transplantation. 2013 Nov 15;96(9):791-9. doi: 10.1097/TP.0b013e3182a3a52b.

PMID:
23958924
40.

Effect of pressure-controlled intermittent coronary sinus occlusion (PICSO) on myocardial ischaemia and reperfusion in a closed-chest porcine model.

Khattab AA, Stieger S, Kamat PJ, Vandenberghe S, Bongoni A, Stone GW, Seiler C, Meier B, Hess OM, Rieben R.

EuroIntervention. 2013 Jul;9(3):398-406. doi: 10.4244/EIJV9I3A63.

41.

Edema is a sign of early acute myocardial infarction on post-mortem magnetic resonance imaging.

Ruder TD, Ebert LC, Khattab AA, Rieben R, Thali MJ, Kamat P.

Forensic Sci Med Pathol. 2013 Dec;9(4):501-5. doi: 10.1007/s12024-013-9459-x. Epub 2013 Jun 20.

PMID:
23783421
42.

Combined inhibition of complement C5 and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis.

Barratt-Due A, Thorgersen EB, Egge K, Pischke S, Sokolov A, Hellerud BC, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn M, Scott H, Mollnes TE.

J Immunol. 2013 Jul 15;191(2):819-27. doi: 10.4049/jimmunol.1201909. Epub 2013 Jun 12.

43.

Botulinum toxin A and B raise blood flow and increase survival of critically ischemic skin flaps.

Schweizer DF, Schweizer R, Zhang S, Kamat P, Contaldo C, Rieben R, Eberli D, Giovanoli P, Erni D, Plock JA.

J Surg Res. 2013 Oct;184(2):1205-13. doi: 10.1016/j.jss.2013.04.004. Epub 2013 Apr 24.

PMID:
23651811
44.

Development of a bead-based multiplex assay for the simultaneous detection of porcine inflammation markers using xMAP technology.

Bongoni AK, Lanz J, Rieben R, Banz Y.

Cytometry A. 2013 Jul;83(7):636-47. doi: 10.1002/cyto.a.22287. Epub 2013 Apr 10.

45.

Microsurgery and liver research: Lumbricus terrestris, a reliable animal model for training?

Leclère FM, Lewbart GA, Rieben R, Vögelin E.

Clin Res Hepatol Gastroenterol. 2013 Apr;37(2):166-70. doi: 10.1016/j.clinre.2012.04.008. Epub 2012 Jul 12.

PMID:
22795317
46.

Ischemia/reperfusion injury of porcine limbs after extracorporeal perfusion.

Müller S, Constantinescu MA, Kiermeir DM, Gajanayake T, Bongoni AK, Vollbach FH, Meoli M, Plock J, Jenni H, Banic A, Rieben R, Vögelin E.

J Surg Res. 2013 May 1;181(1):170-82. doi: 10.1016/j.jss.2012.05.088. Epub 2012 Jun 17.

PMID:
22748598
47.

Assessment of endothelium and inflammatory response at the onset of reperfusion injury in hand surgery.

Kamat P, Juon B, Jossen B, Gajanayake T, Rieben R, Vögelin E.

J Inflamm (Lond). 2012 May 14;9(1):18. doi: 10.1186/1476-9255-9-18.

48.

Pancuronium dose refinement in experimental pigs used in cardiovascular research.

Veres-Nyéki KO, Rieben R, Spadavecchia C, Bergadano A.

Vet Anaesth Analg. 2012 Sep;39(5):529-32. doi: 10.1111/j.1467-2995.2012.00732.x. Epub 2012 Apr 4.

PMID:
22486886
49.

Evaluation of multimeric tyrosine-O-sulfate as a cytoprotectant in an in vivo model of acute myocardial infarction in pigs.

Banz Y, Hess OM, Meier P, Korchagina EY, Gordeeva EA, Robson SC, Gajanayake T, Csizmadia E, Mettler D, Haeberli A, Bovin NV, Rieben R.

Cardiology. 2012;121(1):59-70. doi: 10.1159/000336485. Epub 2012 Mar 2.

PMID:
22398380
50.

Autotransfusion system or integrated automatic suction device in minimized extracorporeal circulation: influence on coagulation and inflammatory response.

Jenni H, Rheinberger J, Czerny M, Gygax E, Rieben R, Krähenbühl E, Carrel T, Stalder M.

Eur J Cardiothorac Surg. 2011 May;39(5):e139-43. doi: 10.1016/j.ejcts.2010.11.082. Epub 2011 Feb 21.

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