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Items: 1 to 50 of 210

1.

RhoBTB1 interacts with ROCKs and inhibits invasion.

Haga RB, Garg R, Collu F, Borda D'Agua B, Menéndez ST, Colomba A, Fraternali F, Ridley AJ.

Biochem J. 2019 Sep 13;476(17):2499-2514. doi: 10.1042/BCJ20190203.

2.

Retraction Notice to: RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress.

Ongusaha PP, Kim HG, Boswell SA, Ridley AJ, Der CJ, Dotto GP, Kim YB, Aaronson SA, Lee SW.

Curr Biol. 2019 Jun 17;29(12):2107. doi: 10.1016/j.cub.2019.05.065. No abstract available.

3.

IGF1R/IRS1 targeting has cytotoxic activity and inhibits PI3K/AKT/mTOR and MAPK signaling in acute lymphoblastic leukemia cells.

Rodrigues Alves APN, Fernandes JC, Fenerich BA, Coelho-Silva JL, Scheucher PS, Simões BP, Rego EM, Ridley AJ, Machado-Neto JA, Traina F.

Cancer Lett. 2019 Aug 1;456:59-68. doi: 10.1016/j.canlet.2019.04.030. Epub 2019 Apr 28.

PMID:
31042587
4.

Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2.

Lucotti S, Cerutti C, Soyer M, Gil-Bernabé AM, Gomes AL, Allen PD, Smart S, Markelc B, Watson K, Armstrong PC, Mitchell JA, Warner TD, Ridley AJ, Muschel RJ.

J Clin Invest. 2019 Mar 25;129(5):1845-1862. doi: 10.1172/JCI121985. eCollection 2019 Mar 25.

5.

Hypoxia suppresses myofibroblast differentiation by changing RhoA activity.

Leinhos L, Peters J, Krull S, Helbig L, Vogler M, Levay M, van Belle GJ, Ridley AJ, Lutz S, Katschinski DM, Zieseniss A.

J Cell Sci. 2019 Feb 18;132(5). pii: jcs223230. doi: 10.1242/jcs.223230.

6.

The STRIPAK complex components FAM40A and FAM40B regulate endothelial cell contractility via ROCKs.

Suryavanshi N, Furmston J, Ridley AJ.

BMC Cell Biol. 2018 Dec 3;19(1):26. doi: 10.1186/s12860-018-0175-y.

7.

Effects of RhoA and RhoC upon the sensitivity of prostate cancer cells to glutamine deprivation.

Bueno De Paiva L, Aline Bernusso V, Machado-Neto JA, Traina F, Ridley AJ, Olalla-Saad ST, Lazarini M.

Small GTPases. 2018 Nov 18:1-7. doi: 10.1080/21541248.2018.1546098. [Epub ahead of print]

PMID:
30449238
8.

Calcium-RasGRP2-Rap1 signaling mediates CD38-induced migration of chronic lymphocytic leukemia cells.

Mele S, Devereux S, Pepper AG, Infante E, Ridley AJ.

Blood Adv. 2018 Jul 10;2(13):1551-1561. doi: 10.1182/bloodadvances.2017014506.

9.

Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression.

Shaw TN, Houston SA, Wemyss K, Bridgeman HM, Barbera TA, Zangerle-Murray T, Strangward P, Ridley AJL, Wang P, Tamoutounour S, Allen JE, Konkel JE, Grainger JR.

J Exp Med. 2018 Jun 4;215(6):1507-1518. doi: 10.1084/jem.20180019. Epub 2018 May 22.

10.

An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration.

Tajadura-Ortega V, Garg R, Allen R, Owczarek C, Bright MD, Kean S, Mohd-Noor A, Grigoriadis A, Elston TC, Hahn KM, Ridley AJ.

BMC Biol. 2018 Mar 6;16(1):29. doi: 10.1186/s12915-018-0489-4.

11.

Rho GTPase signaling complexes in cell migration and invasion.

Lawson CD, Ridley AJ.

J Cell Biol. 2018 Feb 5;217(2):447-457. doi: 10.1083/jcb.201612069. Epub 2017 Dec 12. Review.

12.

Regulation and functions of RhoU and RhoV.

Hodge RG, Ridley AJ.

Small GTPases. 2017 Nov 30:1-8. doi: 10.1080/21541248.2017.1362495. [Epub ahead of print]

PMID:
29189096
13.

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency.

Hurst CD, Alder O, Platt FM, Droop A, Stead LF, Burns JE, Burghel GJ, Jain S, Klimczak LJ, Lindsay H, Roulson JA, Taylor CF, Thygesen H, Cameron AJ, Ridley AJ, Mott HR, Gordenin DA, Knowles MA.

Cancer Cell. 2017 Nov 13;32(5):701-715.e7. doi: 10.1016/j.ccell.2017.08.005.

14.

Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins.

Wylie T, Garg R, Ridley AJ, Conte MR.

PLoS One. 2017 Oct 17;12(10):e0185899. doi: 10.1371/journal.pone.0185899. eCollection 2017.

15.

Endothelial cell-cell adhesion and signaling.

Cerutti C, Ridley AJ.

Exp Cell Res. 2017 Sep 1;358(1):31-38. doi: 10.1016/j.yexcr.2017.06.003. Epub 2017 Jun 8. Review.

16.

The RhoB small GTPase in physiology and disease.

Vega FM, Ridley AJ.

Small GTPases. 2018 Sep 3;9(5):384-393. doi: 10.1080/21541248.2016.1253528. Epub 2016 Nov 22. Review.

17.

Rnd3-induced cell rounding requires interaction with Plexin-B2.

McColl B, Garg R, Riou P, Riento K, Ridley AJ.

J Cell Sci. 2016 Nov 1;129(21):4046-4056. Epub 2016 Sep 21.

18.

Is there a role for IGF-1 in the development of second primary cancers?

Shanmugalingam T, Bosco C, Ridley AJ, Van Hemelrijck M.

Cancer Med. 2016 Nov;5(11):3353-3367. doi: 10.1002/cam4.871. Epub 2016 Oct 13. Review.

19.

Rho GTPases: Regulation and roles in cancer cell biology.

Haga RB, Ridley AJ.

Small GTPases. 2016 Oct;7(4):207-221. Epub 2016 Sep 14. Review.

20.

The RNA-binding protein LARP4 regulates cancer cell migration and invasion.

Seetharaman S, Flemyng E, Shen J, Conte MR, Ridley AJ.

Cytoskeleton (Hoboken). 2016 Nov;73(11):680-690. doi: 10.1002/cm.21336. Epub 2016 Sep 26.

21.

RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress.

Ongusaha PP, Kim HG, Boswell SA, Ridley AJ, Der CJ, Dotto GP, Kim YB, Aaronson SA, Lee SW.

Curr Biol. 2016 Aug 22;26(16):2221-2222. doi: 10.1016/j.cub.2016.07.072. No abstract available.

22.

Open questions: what about the 'other' Rho GTPases?

Ridley AJ.

BMC Biol. 2016 Aug 4;14:64. doi: 10.1186/s12915-016-0289-7.

23.

Regulating Rho GTPases and their regulators.

Hodge RG, Ridley AJ.

Nat Rev Mol Cell Biol. 2016 Aug;17(8):496-510. doi: 10.1038/nrm.2016.67. Epub 2016 Jun 15. Review.

PMID:
27301673
24.

Ellagitannin-rich cloudberry inhibits hepatocyte growth factor induced cell migration and phosphatidylinositol 3-kinase/AKT activation in colon carcinoma cells and tumors in Min mice.

Pajari AM, Päivärinta E, Paavolainen L, Vaara E, Koivumäki T, Garg R, Heiman-Lindh A, Mutanen M, Marjomäki V, Ridley AJ.

Oncotarget. 2016 Jul 12;7(28):43907-43923. doi: 10.18632/oncotarget.9724.

25.

Anne Ridley: Networking with Rho GTPases.

Ridley AJ.

Trends Cell Biol. 2016 Jul;26(7):465-466. doi: 10.1016/j.tcb.2016.04.005. Epub 2016 May 8. No abstract available.

PMID:
27166090
26.

RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border.

Marcos-Ramiro B, García-Weber D, Barroso S, Feito J, Ortega MC, Cernuda-Morollón E, Reglero-Real N, Fernández-Martín L, Durán MC, Alonso MA, Correas I, Cox S, Ridley AJ, Millán J.

J Cell Biol. 2016 May 9;213(3):385-402. doi: 10.1083/jcb.201504038. Epub 2016 May 2.

27.

The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease.

Hartmann S, Ridley AJ, Lutz S.

Front Pharmacol. 2015 Nov 20;6:276. doi: 10.3389/fphar.2015.00276. eCollection 2015. Review.

28.

Dual inhibition of histone deacetylases and phosphoinositide 3-kinases: effects on Burkitt lymphoma cell growth and migration.

Ferreira AC, de-Freitas-Junior JC, Morgado-Díaz JA, Ridley AJ, Klumb CE.

J Leukoc Biol. 2016 Apr;99(4):569-78. doi: 10.1189/jlb.2A0415-162R. Epub 2015 Nov 11.

PMID:
26561567
29.

Rho GTPase signalling in cell migration.

Ridley AJ.

Curr Opin Cell Biol. 2015 Oct;36:103-12. doi: 10.1016/j.ceb.2015.08.005. Epub 2015 Sep 10. Review.

30.

RhoC and ROCKs regulate cancer cell interactions with endothelial cells.

Reymond N, Im JH, Garg R, Cox S, Soyer M, Riou P, Colomba A, Muschel RJ, Ridley AJ.

Mol Oncol. 2015 Jun;9(6):1043-55. doi: 10.1016/j.molonc.2015.01.004. Epub 2015 Jan 22.

31.

The Rho GTPase RhoB regulates cadherin expression and epithelial cell-cell interaction.

Vega FM, Thomas M, Reymond N, Ridley AJ.

Cell Commun Signal. 2015 Jan 29;13:6. doi: 10.1186/s12964-015-0085-y.

32.

Diverse matrix metalloproteinase functions regulate cancer amoeboid migration.

Orgaz JL, Pandya P, Dalmeida R, Karagiannis P, Sanchez-Laorden B, Viros A, Albrengues J, Nestle FO, Ridley AJ, Gaggioli C, Marais R, Karagiannis SN, Sanz-Moreno V.

Nat Commun. 2014 Jun 25;5:4255. doi: 10.1038/ncomms5255.

33.

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

King SJ, Nowak K, Suryavanshi N, Holt I, Shanahan CM, Ridley AJ.

Cytoskeleton (Hoboken). 2014 Jul;71(7):423-34. doi: 10.1002/cm.21182. Epub 2014 Jun 25.

PMID:
24931616
34.

Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation.

Fu H, Kishore M, Gittens B, Wang G, Coe D, Komarowska I, Infante E, Ridley AJ, Cooper D, Perretti M, Marelli-Berg FM.

Nat Commun. 2014 Mar 14;5:3436. doi: 10.1038/ncomms4436.

35.

An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration.

Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, Ridley AJ, Friedel RH, Parsons M, Guillemot F.

Nat Commun. 2014 Feb 27;5:3405. doi: 10.1038/ncomms4405.

36.

Analyzing the roles of Rho GTPases in cancer cell migration with a live cell imaging 3D-morphology-based assay.

Colomba A, Ridley AJ.

Methods Mol Biol. 2014;1120:327-37. doi: 10.1007/978-1-62703-791-4_21.

PMID:
24470035
37.

Crossing the endothelial barrier during metastasis.

Reymond N, d'Água BB, Ridley AJ.

Nat Rev Cancer. 2013 Dec;13(12):858-70. doi: 10.1038/nrc3628. Review.

PMID:
24263189
38.

Rho and Rap guanosine triphosphatase signaling in B cells and chronic lymphocytic leukemia.

Mele S, Devereux S, Ridley AJ.

Leuk Lymphoma. 2014 Sep;55(9):1993-2001. doi: 10.3109/10428194.2013.866666. Epub 2013 Dec 31. Review.

PMID:
24237579
39.

Roles of Rho GTPases in leucocyte and leukaemia cell transendothelial migration.

Infante E, Ridley AJ.

Philos Trans R Soc Lond B Biol Sci. 2013 Sep 23;368(1629):20130013. doi: 10.1098/rstb.2013.0013. Print 2013. Review.

40.

Determining Rho GTPase activity by an affinity-precipitation assay.

Suryavanshi N, Ridley AJ.

Methods Mol Biol. 2013;1046:191-202. doi: 10.1007/978-1-62703-538-5_11.

PMID:
23868589
41.

FMNL1 promotes proliferation and migration of leukemia cells.

Favaro P, Traina F, Machado-Neto JA, Lazarini M, Lopes MR, Pereira JK, Costa FF, Infante E, Ridley AJ, Saad ST.

J Leukoc Biol. 2013 Sep;94(3):503-12. doi: 10.1189/jlb.0113057. Epub 2013 Jun 25.

PMID:
23801653
42.

14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins.

Riou P, Kjær S, Garg R, Purkiss A, George R, Cain RJ, Bineva G, Reymond N, McColl B, Thompson AJ, O'Reilly N, McDonald NQ, Parker PJ, Ridley AJ.

Cell. 2013 Apr 25;153(3):640-53. doi: 10.1016/j.cell.2013.03.044. Erratum in: Cell. 2013 May 23;153(5):1164.

43.

RhoA, RhoB and RhoC have different roles in cancer cell migration.

Ridley AJ.

J Microsc. 2013 Sep;251(3):242-9. doi: 10.1111/jmi.12025. Epub 2013 Mar 12. Review.

44.

Rnd3 induces stress fibres in endothelial cells through RhoB.

Gottesbühren U, Garg R, Riou P, McColl B, Brayson D, Ridley AJ.

Biol Open. 2013 Feb 15;2(2):210-6. doi: 10.1242/bio.20123574. Epub 2012 Dec 10.

45.

MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression.

Aranda JF, Reglero-Real N, Marcos-Ramiro B, Ruiz-Sáenz A, Fernández-Martín L, Bernabé-Rubio M, Kremer L, Ridley AJ, Correas I, Alonso MA, Millán J.

Mol Biol Cell. 2013 Feb;24(4):483-94. doi: 10.1091/mbc.E11-11-0914. Epub 2012 Dec 21.

46.

ARHGAP21 is a RhoGAP for RhoA and RhoC with a role in proliferation and migration of prostate adenocarcinoma cells.

Lazarini M, Traina F, Machado-Neto JA, Barcellos KS, Moreira YB, Brandão MM, Verjovski-Almeida S, Ridley AJ, Saad ST.

Biochim Biophys Acta. 2013 Feb;1832(2):365-74. doi: 10.1016/j.bbadis.2012.11.010. Epub 2012 Nov 28.

47.

Cdc42 promotes transendothelial migration of cancer cells through β1 integrin.

Reymond N, Im JH, Garg R, Vega FM, Borda d'Agua B, Riou P, Cox S, Valderrama F, Muschel RJ, Ridley AJ.

J Cell Biol. 2012 Nov 12;199(4):653-68. doi: 10.1083/jcb.201205169.

48.

Different PI 3-kinase inhibitors have distinct effects on endothelial permeability and leukocyte transmigration.

Cain RJ, Vanhaesebroeck B, Ridley AJ.

Int J Biochem Cell Biol. 2012 Nov;44(11):1929-36. doi: 10.1016/j.biocel.2012.07.009. Epub 2012 Jul 17.

PMID:
22814170
49.

RhoB regulates cell migration through altered focal adhesion dynamics.

Vega FM, Colomba A, Reymond N, Thomas M, Ridley AJ.

Open Biol. 2012 May;2(5):120076. doi: 10.1098/rsob.120076.

50.

Crosstalk between reticular adherens junctions and platelet endothelial cell adhesion molecule-1 regulates endothelial barrier function.

Fernández-Martín L, Marcos-Ramiro B, Bigarella CL, Graupera M, Cain RJ, Reglero-Real N, Jiménez A, Cernuda-Morollón E, Correas I, Cox S, Ridley AJ, Millán J.

Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):e90-102. doi: 10.1161/ATVBAHA.112.252080. Epub 2012 Jun 21.

PMID:
22723439

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