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Items: 33

1.

Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis.

Strnad P, Buch S, Hamesch K, Fischer J, Rosendahl J, Schmelz R, Brueckner S, Brosch M, Heimes CV, Woditsch V, Scholten D, Nischalke HD, Janciauskiene S, Mandorfer M, Trauner M, Way MJ, McQuillin A, Reichert MC, Krawczyk M, Casper M, Lammert F, Braun F, von Schönfels W, Hinz S, Burmeister G, Hellerbrand C, Teufel A, Feldman A, Schattenberg JM, Bantel H, Pathil A, Demir M, Kluwe J, Boettler T, Ridinger M, Wodarz N, Soyka M, Rietschel M, Kiefer F, Weber T, Marhenke S, Vogel A, Hinrichsen H, Canbay A, Schlattjan M, Sosnowsky K, Sarrazin C, von Felden J, Geier A, Deltenre P, Sipos B, Schafmayer C, Nothnagel M, Aigner E, Datz C, Stickel F, Morgan MY, Hampe J, Berg T, Trautwein C.

Gut. 2018 Aug 1. pii: gutjnl-2018-316228. doi: 10.1136/gutjnl-2018-316228. [Epub ahead of print]

PMID:
30068662
2.

Shared genetic etiology between alcohol dependence and major depressive disorder.

Foo JC, Streit F, Treutlein J, Ripke S, Witt SH, Strohmaier J, Degenhardt F, Forstner AJ, Hoffmann P, Soyka M, Dahmen N, Scherbaum N, Wodarz N, Heilmann-Heimbach S, Herms S, Cichon S, Preuss U, Gaebel W, Ridinger M, Hoffmann S, Schulze TG, Maier W, Zill P, Müller-Myhsok B, Ising M, Lucae S, Nöthen MM, Mann K, Kiefer F, Rietschel M, Frank J; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium.

Psychiatr Genet. 2018 Aug;28(4):66-70. doi: 10.1097/YPG.0000000000000201.

3.

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.

Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP.

Gut. 2017 Jul 28. pii: gutjnl-2017-314454. doi: 10.1136/gutjnl-2017-314454. [Epub ahead of print]

4.

Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis.

Treutlein J, Frank J, Streit F, Reinbold CS, Juraeva D, Degenhardt F, Rietschel L, Witt SH, Forstner AJ, Ridinger M, Strohmaier J, Wodarz N, Dukal H, Foo JC, Hoffmann P, Herms S, Heilmann-Heimbach S, Soyka M, Maier W, Gaebel W, Dahmen N, Scherbaum N, Müller-Myhsok B, Lucae S, Ising M, Stickel F, Berg T, Roggenbuck U, Jöckel KH, Scholz H, Zimmermann US, Buch S, Sommer WH, Spanagel R, Brors B, Cichon S, Mann K, Kiefer F, Hampe J, Rosendahl J, Nöthen MM, Rietschel M.

Genes (Basel). 2017 Jul 17;8(7). pii: E183. doi: 10.3390/genes8070183.

5.

Recovery from alcohol dependence: Do smoking indicators predict abstinence?

Hufnagel A, Frick U, Ridinger M, Wodarz N.

Am J Addict. 2017 Jun;26(4):366-373. doi: 10.1111/ajad.12535. Epub 2017 Apr 4.

PMID:
28376287
6.

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms.

Adkins AE, Hack LM, Bigdeli TB, Williamson VS, McMichael GO, Mamdani M, Edwards AC, Aliev F, Chan RF, Bhandari P, Raabe RC, Alaimo JT, Blackwell GG, Moscati A, Poland RS, Rood B, Patterson DG, Walsh D; Collaborative Study of the Genetics of Alcoholism Consortium, Whitfield JB, Zhu G, Montgomery GW, Henders AK, Martin NG, Heath AC, Madden PAF, Frank J, Ridinger M, Wodarz N, Soyka M, Zill P, Ising M, Nöthen MM, Kiefer F, Rietschel M; German Study of the Genetics of Addiction Consortium, Gelernter J, Sherva R, Koesterer R, Almasy L, Zhao H, Kranzler HR, Farrer LA, Maher BS, Prescott CA, Dick DM, Bacanu SA, Mathies LD, Davies AG, Vladimirov VI, Grotewiel M, Bowers MS, Bettinger JC, Webb BT, Miles MF, Kendler KS, Riley BP.

Alcohol Clin Exp Res. 2017 May;41(5):911-928. doi: 10.1111/acer.13362. Epub 2017 Mar 30.

7.

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis.

Buch S, Stickel F, Trépo E, Way M, Herrmann A, Nischalke HD, Brosch M, Rosendahl J, Berg T, Ridinger M, Rietschel M, McQuillin A, Frank J, Kiefer F, Schreiber S, Lieb W, Soyka M, Semmo N, Aigner E, Datz C, Schmelz R, Brückner S, Zeissig S, Stephan AM, Wodarz N, Devière J, Clumeck N, Sarrazin C, Lammert F, Gustot T, Deltenre P, Völzke H, Lerch MM, Mayerle J, Eyer F, Schafmayer C, Cichon S, Nöthen MM, Nothnagel M, Ellinghaus D, Huse K, Franke A, Zopf S, Hellerbrand C, Moreno C, Franchimont D, Morgan MY, Hampe J.

Nat Genet. 2015 Dec;47(12):1443-8. doi: 10.1038/ng.3417. Epub 2015 Oct 19.

8.

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.

Schwantes-An TH, Zhang J, Chen LS, Hartz SM, Culverhouse RC, Chen X, Coon H, Frank J, Kamens HM, Konte B, Kovanen L, Latvala A, Legrand LN, Maher BS, Melroy WE, Nelson EC, Reid MW, Robinson JD, Shen PH, Yang BZ, Andrews JA, Aveyard P, Beltcheva O, Brown SA, Cannon DS, Cichon S, Corley RP, Dahmen N, Degenhardt L, Foroud T, Gaebel W, Giegling I, Glatt SJ, Grucza RA, Hardin J, Hartmann AM, Heath AC, Herms S, Hodgkinson CA, Hoffmann P, Hops H, Huizinga D, Ising M, Johnson EO, Johnstone E, Kaneva RP, Kendler KS, Kiefer F, Kranzler HR, Krauter KS, Levran O, Lucae S, Lynskey MT, Maier W, Mann K, Martin NG, Mattheisen M, Montgomery GW, Müller-Myhsok B, Murphy MF, Neale MC, Nikolov MA, Nishita D, Nöthen MM, Nurnberger J, Partonen T, Pergadia ML, Reynolds M, Ridinger M, Rose RJ, Rouvinen-Lagerström N, Scherbaum N, Schmäl C, Soyka M, Stallings MC, Steffens M, Treutlein J, Tsuang M, Wall TL, Wodarz N, Yuferov V, Zill P, Bergen AW, Chen J, Cinciripini PM, Edenberg HJ, Ehringer MA, Ferrell RE, Gelernter J, Goldman D, Hewitt JK, Hopfer CJ, Iacono WG, Kaprio J, Kreek MJ, Kremensky IM, Madden PA, McGue M, Munafò MR, Philibert RA, Rietschel M, Roy A, Rujescu D, Saarikoski ST, Swan GE, Todorov AA, Vanyukov MM, Weiss RB, Bierut LJ, Saccone NL.

Behav Genet. 2016 Mar;46(2):151-69. doi: 10.1007/s10519-015-9737-3. Epub 2015 Sep 21.

9.

XRCC5 as a risk gene for alcohol dependence: evidence from a genome-wide gene-set-based analysis and follow-up studies in Drosophila and humans.

Juraeva D, Treutlein J, Scholz H, Frank J, Degenhardt F, Cichon S, Ridinger M, Mattheisen M, Witt SH, Lang M, Sommer WH, Hoffmann P, Herms S, Wodarz N, Soyka M, Zill P, Maier W, Jünger E, Gaebel W, Dahmen N, Scherbaum N, Schmäl C, Steffens M, Lucae S, Ising M, Smolka MN, Zimmermann US, Müller-Myhsok B, Nöthen MM, Mann K, Kiefer F, Spanagel R, Brors B, Rietschel M.

Neuropsychopharmacology. 2015 Jan;40(2):361-71. doi: 10.1038/npp.2014.178. Epub 2014 Jul 18.

10.

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

Gelernter J, Kranzler HR, Sherva R, Almasy L, Koesterer R, Smith AH, Anton R, Preuss UW, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer LA.

Mol Psychiatry. 2014 Jan;19(1):41-9. doi: 10.1038/mp.2013.145. Epub 2013 Oct 29.

11.

Association of functional DBH genetic variants with alcohol dependence risk and related depression and suicide attempt phenotypes: results from a large multicenter association study.

Preuss UW, Wurst FM, Ridinger M, Rujescu D, Fehr C, Koller G, Bondy B, Wodarz N, Soyka M, Zill P.

Drug Alcohol Depend. 2013 Dec 1;133(2):459-67. doi: 10.1016/j.drugalcdep.2013.07.002. Epub 2013 Jul 30.

PMID:
23906995
12.

αCaMKII autophosphorylation controls the establishment of alcohol drinking behavior.

Easton AC, Lucchesi W, Lourdusamy A, Lenz B, Solati J, Golub Y, Lewczuk P, Fernandes C, Desrivieres S, Dawirs RR, Moll GH, Kornhuber J, Frank J, Hoffmann P, Soyka M, Kiefer F; GESGA Consortium, Schumann G, Peter Giese K, Müller CP, Treutlein J, Cichon S, Ridinger M, Mattheisen P, Herms S, Wodarz N, Zill P, Maier W, Mössner R, Gaebel W, Dahmen N, Scherbaum N, Schmäl C, Steffens M, Lucae S, Ising M, Müller-Myhsok B, Nöthen MM, Mann K, Rietschel M.

Neuropsychopharmacology. 2013 Aug;38(9):1636-47. doi: 10.1038/npp.2013.60. Epub 2013 Mar 4. Erratum in: Neuropsychopharmacology. 2013 Dec;38(13):2735.

13.

Possible association between OPRM1 genetic variance at the 118 locus and alcohol dependence in a large treatment sample: relationship to alcohol dependence symptoms.

Koller G, Zill P, Rujescu D, Ridinger M, Pogarell O, Fehr C, Wodarz N, Bondy B, Soyka M, Preuss UW.

Alcohol Clin Exp Res. 2012 Jul;36(7):1230-6. doi: 10.1111/j.1530-0277.2011.01714.x. Epub 2012 Feb 6.

PMID:
22309038
14.

Analysis of carbohydrate deficient transferrin serum levels during abstinence.

Ridinger M, Köhl P, Gäbele E, Wodarz N, Schmitz G, Kiefer P, Hellerbrand C.

Exp Mol Pathol. 2012 Feb;92(1):50-3. doi: 10.1016/j.yexmp.2011.10.005. Epub 2011 Oct 18.

PMID:
22032939
15.

Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.

Frank J, Cichon S, Treutlein J, Ridinger M, Mattheisen M, Hoffmann P, Herms S, Wodarz N, Soyka M, Zill P, Maier W, Mössner R, Gaebel W, Dahmen N, Scherbaum N, Schmäl C, Steffens M, Lucae S, Ising M, Müller-Myhsok B, Nöthen MM, Mann K, Kiefer F, Rietschel M.

Addict Biol. 2012 Jan;17(1):171-80. doi: 10.1111/j.1369-1600.2011.00395.x. Epub 2011 Oct 18.

16.

Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking.

Dong L, Bilbao A, Laucht M, Henriksson R, Yakovleva T, Ridinger M, Desrivieres S, Clarke TK, Lourdusamy A, Smolka MN, Cichon S, Blomeyer D, Treutlein J, Perreau-Lenz S, Witt S, Leonardi-Essmann F, Wodarz N, Zill P, Soyka M, Albrecht U, Rietschel M, Lathrop M, Bakalkin G, Spanagel R, Schumann G.

Am J Psychiatry. 2011 Oct;168(10):1090-8. doi: 10.1176/appi.ajp.2011.10111579. Epub 2011 Aug 9.

PMID:
21828288
17.

Sex-specific role for adenylyl cyclase type 7 in alcohol dependence.

Desrivières S, Pronko SP, Lourdusamy A, Ducci F, Hoffman PL, Wodarz N, Ridinger M, Rietschel M, Zelenika D, Lathrop M, Schumann G, Tabakoff B.

Biol Psychiatry. 2011 Jun 1;69(11):1100-8. doi: 10.1016/j.biopsych.2011.01.037. Epub 2011 Apr 8.

18.

[Indicators of course of inpatient therapy in offenders with substance dependency].

Fries D, Endrass J, Ridinger M, Urbaniok F, Rossegger A.

Fortschr Neurol Psychiatr. 2011 Jul;79(7):404-10. doi: 10.1055/s-0029-1245962. Epub 2011 Mar 21. German.

PMID:
21425031
19.

KCNJ6 is associated with adult alcohol dependence and involved in gene × early life stress interactions in adolescent alcohol drinking.

Clarke TK, Laucht M, Ridinger M, Wodarz N, Rietschel M, Maier W, Lathrop M, Lourdusamy A, Zimmermann US, Desrivieres S, Schumann G.

Neuropsychopharmacology. 2011 May;36(6):1142-8. doi: 10.1038/npp.2010.247. Epub 2011 Feb 9.

20.

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians.

Stickel F, Buch S, Lau K, Meyer zu Schwabedissen H, Berg T, Ridinger M, Rietschel M, Schafmayer C, Braun F, Hinrichsen H, Günther R, Arlt A, Seeger M, Müller S, Seitz HK, Soyka M, Lerch M, Lammert F, Sarrazin C, Kubitz R, Häussinger D, Hellerbrand C, Bröring D, Schreiber S, Kiefer F, Spanagel R, Mann K, Datz C, Krawczak M, Wodarz N, Völzke H, Hampe J.

Hepatology. 2011 Jan;53(1):86-95. doi: 10.1002/hep.24017. Epub 2010 Dec 7.

PMID:
21254164
21.

Multiple polymorphisms in genes of the adrenergic stress system confer vulnerability to alcohol abuse.

Clarke TK, Dempster E, Docherty SJ, Desrivieres S, Lourdsamy A, Wodarz N, Ridinger M, Maier W, Rietschel M, Schumann G.

Addict Biol. 2012 Jan;17(1):202-8. doi: 10.1111/j.1369-1600.2010.00263.x. Epub 2010 Nov 11.

PMID:
21070505
22.

Association of ADH4 genetic variants with alcohol dependence risk and related phenotypes: results from a larger multicenter association study.

Preuss UW, Ridinger M, Rujescu D, Samochowiec J, Fehr C, Wurst FM, Koller G, Bondy B, Wodarz N, Debniak T, Grzywacz A, Soyka M, Zill P.

Addict Biol. 2011 Apr;16(2):323-33. doi: 10.1111/j.1369-1600.2010.00236.x.

PMID:
20626721
23.

No association of alcohol dependence with HOMER 1 and 2 genetic variants.

Preuss UW, Ridinger M, Rujescu D, Fehr C, Koller G, Wodarz N, Bondy B, Soyka M, Wong WM, Zill P.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jul;153B(5):1102-9. doi: 10.1002/ajmg.b.31074.

PMID:
20333726
24.

A genome-wide association study of alcohol dependence.

Bierut LJ, Agrawal A, Bucholz KK, Doheny KF, Laurie C, Pugh E, Fisher S, Fox L, Howells W, Bertelsen S, Hinrichs AL, Almasy L, Breslau N, Culverhouse RC, Dick DM, Edenberg HJ, Foroud T, Grucza RA, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Krueger RF, Kuperman S, Lynskey M, Mann K, Neuman RJ, Nöthen MM, Nurnberger JI Jr, Porjesz B, Ridinger M, Saccone NL, Saccone SF, Schuckit MA, Tischfield JA, Wang JC, Rietschel M, Goate AM, Rice JP; Gene, Environment Association Studies Consortium.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5082-7. doi: 10.1073/pnas.0911109107. Epub 2010 Mar 2.

25.

Genome-wide association study of alcohol dependence.

Treutlein J, Cichon S, Ridinger M, Wodarz N, Soyka M, Zill P, Maier W, Moessner R, Gaebel W, Dahmen N, Fehr C, Scherbaum N, Steffens M, Ludwig KU, Frank J, Wichmann HE, Schreiber S, Dragano N, Sommer WH, Leonardi-Essmann F, Lourdusamy A, Gebicke-Haerter P, Wienker TF, Sullivan PF, Nöthen MM, Kiefer F, Spanagel R, Mann K, Rietschel M.

Arch Gen Psychiatry. 2009 Jul;66(7):773-84. doi: 10.1001/archgenpsychiatry.2009.83.

26.

[The impact of attachment styles and ADHD on alcohol dependence].

Ridinger M, König S, Lange K, Wodarz N.

Nervenarzt. 2009 Jul;80(7):827-32. doi: 10.1007/s00115-009-2729-x. German.

PMID:
19506828
27.

Nutraceuticals: miracle or meme?

Ridinger MH.

Clin Pharmacol Ther. 2007 Oct;82(4):352-6.

PMID:
17851571
28.

In vivo molecular imaging biomarkers: clinical pharmacology's new "PET"?

Nutt R, Vento LJ, Ridinger MH.

Clin Pharmacol Ther. 2007 Jun;81(6):792-5.

PMID:
17505491
29.

Is the Dx for welfare Rx?

Ridinger MH.

Clin Pharmacol Ther. 2007 May;81(5):624-6.

PMID:
17438535
30.

The electronic prescription conundrum: why "e-Rx" isn't so "e-Z".

Ridinger MH.

Clin Pharmacol Ther. 2007 Jan;81(1):13-5. No abstract available.

PMID:
17185989
31.

Predictive modeling points way to future risk status.

Ridinger MH, Rice JJ.

Health Manag Technol. 2000 Feb;21(2):10-2. No abstract available.

PMID:
10787539
32.

Novel organism associated with chronic diarrhoea in AIDS.

Hart AS, Ridinger MT, Soundarajan R, Peters CS, Swiatlo AL, Kocka FE.

Lancet. 1990 Jan 20;335(8682):169-70. No abstract available.

PMID:
1967459
33.

Endothelium-dependent gender differences in the response of the rat aorta.

Maddox YT, Falcon JG, Ridinger M, Cunard CM, Ramwell PW.

J Pharmacol Exp Ther. 1987 Feb;240(2):392-5.

PMID:
3468242

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