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Items: 1 to 50 of 143


Glucocorticoid-driven transcriptomes in human airway epithelial cells: commonalities, differences and functional insight from cell lines and primary cells.

Mostafa MM, Rider CF, Shah S, Traves SL, Gordon PMK, Miller-Larsson A, Leigh R, Newton R.

BMC Med Genomics. 2019 Jan 31;12(1):29. doi: 10.1186/s12920-018-0467-2.


Finding the bad actor: Challenges in identifying toxic constituents in botanical dietary supplements.

Roberts GK, Gardner D, Foster PM, Howard PC, Lui E, Walker L, van Breemen RB, Auerbach SS, Rider C.

Food Chem Toxicol. 2019 Feb;124:431-438. doi: 10.1016/j.fct.2018.12.026. Epub 2018 Dec 21. Review.


Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array.

McEwen LM, Jones MJ, Lin DTS, Edgar RD, Husquin LT, MacIsaac JL, Ramadori KE, Morin AM, Rider CF, Carlsten C, Quintana-Murci L, Horvath S, Kobor MS.

Clin Epigenetics. 2018 Oct 16;10(1):123. doi: 10.1186/s13148-018-0556-2.


Follow that botanical: Challenges and recommendations for assessing absorption, distribution, metabolism and excretion of botanical dietary supplements.

Waidyanatha S, Ryan K, Roe AL, Jia W, Paine MF, Ferguson S, Gurley BJ, Welch K, Chow MSS, Devito M, Rider C.

Food Chem Toxicol. 2018 Nov;121:194-202. doi: 10.1016/j.fct.2018.08.062. Epub 2018 Aug 28.


Air pollution and resistance to inhaled glucocorticoids: Evidence, mechanisms and gaps to fill.

Rider CF, Carlsten C.

Pharmacol Ther. 2019 Feb;194:1-21. doi: 10.1016/j.pharmthera.2018.08.005. Epub 2018 Aug 20. Review.


Long-Acting β2-Adrenoceptor Agonists Enhance Glucocorticoid Receptor (GR)-Mediated Transcription by Gene-Specific Mechanisms Rather Than Generic Effects via GR.

Rider CF, Altonsy MO, Mostafa MM, Shah SV, Sasse S, Manson ML, Yan D, Kärrman-Mårdh C, Miller-Larsson A, Gerber AN, Giembycz MA, Newton R.

Mol Pharmacol. 2018 Sep;94(3):1031-1046. doi: 10.1124/mol.118.112755. Epub 2018 Jun 29.


The localisation of the heparin binding sites of human and murine interleukin-12 within the carboxyterminal domain of the P40 subunit.

Garnier P, Mummery R, Forster MJ, Mulloy B, Gibbs RV, Rider CC.

Cytokine. 2018 Oct;110:159-168. doi: 10.1016/j.cyto.2018.04.014. Epub 2018 May 10.


How similar is similar enough? A sufficient similarity case study with Ginkgo biloba extract.

Catlin NR, Collins BJ, Auerbach SS, Ferguson SS, Harnly JM, Gennings C, Waidyanatha S, Rice GE, Smith-Roe SL, Witt KL, Rider CV.

Food Chem Toxicol. 2018 Aug;118:328-339. doi: 10.1016/j.fct.2018.05.013. Epub 2018 May 9.


Getting to the Root of the Matter: Challenges and Recommendations for Assessing the Safety of Botanical Dietary Supplements.

Rider CV, Walker NJ, Waidyanatha S.

Clin Pharmacol Ther. 2018 Sep;104(3):429-431. doi: 10.1002/cpt.1088. Epub 2018 May 10.


Effects of Controlled Diesel Exhaust and Allergen Exposure on microRNA and Gene Expression in Humans. Modulation of Lung Inflammatory Markers Associated with Asthma.

Rider CF, Yamamoto M, Günther OP, Singh A, Hirota JA, Tebbutt SJ, Carlsten C.

Ann Am Thorac Soc. 2018 Apr;15(Supplement_2):S130-S131. doi: 10.1513/AnnalsATS.201706-479MG.


Surgical Treatment of Supracondylar Humeral Fractures in a Freestanding Ambulatory Surgery Center is as Safe as and Faster and More Cost-Effective Than in a Children's Hospital.

Rider CM, Hong VY, Westbrooks TJ, Wang J, Sheffer BW, Kelly DM, Spence DD, Flynn JM, Sawyer JR.

J Pediatr Orthop. 2018 Jul;38(6):e343-e348. doi: 10.1097/BPO.0000000000001171.


Naturally complex: Perspectives and challenges associated with Botanical Dietary Supplement Safety assessment.

Shipkowski KA, Betz JM, Birnbaum LS, Bucher JR, Coates PM, Hopp DC, MacKay D, Oketch-Rabah H, Walker NJ, Welch C, Rider CV.

Food Chem Toxicol. 2018 Aug;118:963-971. doi: 10.1016/j.fct.2018.04.007. Epub 2018 Apr 4. Review.


Inhaled diesel exhaust alters the allergen-induced bronchial secretome in humans.

Mookherjee N, Piyadasa H, Ryu MH, Rider CF, Ezzati P, Spicer V, Carlsten C.

Eur Respir J. 2018 Jan 25;51(1). pii: 1701385. doi: 10.1183/13993003.01385-2017. Print 2018 Jan.


Inhibition of ABCC4 potentiates combination beta agonist and glucocorticoid responses in human airway epithelial cells.

Huff RD, Rider CF, Yan D, Newton R, Giembycz MA, Carlsten C, Hirota JA.

J Allergy Clin Immunol. 2018 Mar;141(3):1127-1130.e5. doi: 10.1016/j.jaci.2017.10.011. Epub 2017 Dec 6. No abstract available.


Heparin, Heparan Sulphate and the TGF-β Cytokine Superfamily.

Rider CC, Mulloy B.

Molecules. 2017 Apr 29;22(5). pii: E713. doi: 10.3390/molecules22050713. Review.


Novel flow cytometry approach to identify bronchial epithelial cells from healthy human airways.

Maestre-Batlle D, Pena OM, Hirota JA, Gunawan E, Rider CF, Sutherland D, Alexis NE, Carlsten C.

Sci Rep. 2017 Feb 6;7:42214. doi: 10.1038/srep42214.


Traffic-related air pollution and allergic disease: an update in the context of global urbanization.

Carlsten C, Rider CF.

Curr Opin Allergy Clin Immunol. 2017 Apr;17(2):85-89. doi: 10.1097/ACI.0000000000000351. Review.


An inhaled dose of budesonide induces genes involved in transcription and signaling in the human airways: enhancement of anti- and proinflammatory effector genes.

Leigh R, Mostafa MM, King EM, Rider CF, Shah S, Dumonceaux C, Traves SL, McWhae A, Kolisnik T, Kooi C, Slater DM, Kelly MM, Bieda M, Miller-Larsson A, Newton R.

Pharmacol Res Perspect. 2016 Jul 12;4(4):e00243. doi: 10.1002/prp2.243. eCollection 2016 Aug.


The binding of the bone morphogenetic protein antagonist gremlin to kidney heparan sulfate: Such binding is not essential for BMP antagonism.

Tatsinkam AJ, Rune N, Smith J, Norman JT, Mulloy B, Rider CC.

Int J Biochem Cell Biol. 2017 Feb;83:39-46. doi: 10.1016/j.biocel.2016.12.006. Epub 2016 Dec 12.


Statistical Approaches for Assessing Health Effects of Environmental Chemical Mixtures in Epidemiology: Lessons from an Innovative Workshop.

Taylor KW, Joubert BR, Braun JM, Dilworth C, Gennings C, Hauser R, Heindel JJ, Rider CV, Webster TF, Carlin DJ.

Environ Health Perspect. 2016 Dec 1;124(12):A227-A229. No abstract available.


Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers.

Rider CF, Yamamoto M, Günther OP, Hirota JA, Singh A, Tebbutt SJ, Carlsten C.

J Allergy Clin Immunol. 2016 Dec;138(6):1690-1700. doi: 10.1016/j.jaci.2016.02.038. Epub 2016 Apr 24.


Dermal Exposure to Cumene Hydroperoxide: Assessing Its Toxic Relevance and Oxidant Potential.

Rider CV, Chan P, Herbert RA, Kissling GE, Fomby LM, Hejtmancik MR, Witt KL, Waidyanatha S, Travlos GS, Kadiiska MB.

Toxicol Pathol. 2016 Jul;44(5):749-62. doi: 10.1177/0192623316636712. Epub 2016 Mar 16.


Dose Addition Models Based on Biologically Relevant Reductions in Fetal Testosterone Accurately Predict Postnatal Reproductive Tract Alterations by a Phthalate Mixture in Rats.

Howdeshell KL, Rider CV, Wilson VS, Furr JR, Lambright CR, Gray LE Jr.

Toxicol Sci. 2015 Dec;148(2):488-502. doi: 10.1093/toxsci/kfv196. Epub 2015 Sep 8.


Simple Triage Algorithm and Rapid Treatment and Sort, Assess, Lifesaving, Interventions, Treatment, and Transportation mass casualty triage methods for sensitivity, specificity, and predictive values.

Bhalla MC, Frey J, Rider C, Nord M, Hegerhorst M.

Am J Emerg Med. 2015 Nov;33(11):1687-91. doi: 10.1016/j.ajem.2015.08.021. Epub 2015 Aug 14.


The Bone Morphogenetic Proteins and Their Antagonists.

Mulloy B, Rider CC.

Vitam Horm. 2015;99:63-90. doi: 10.1016/bs.vh.2015.06.004. Epub 2015 Jul 15. Review.


Mapping the heparin-binding site of the BMP antagonist gremlin by site-directed mutagenesis based on predictive modelling.

Tatsinkam AJ, Mulloy B, Rider CC.

Biochem J. 2015 Aug 15;470(1):53-64. doi: 10.1042/BJ20150228. Epub 2015 Jun 11.


Developing a Systematic Approach to Obstetric Emergencies.

Green M, Rider C, Ratcliff D, Woodring BC.

J Obstet Gynecol Neonatal Nurs. 2015 Sep-Oct;44(5):677-82. doi: 10.1111/1552-6909.12729. Epub 2015 Jul 15.


Cytokine-induced loss of glucocorticoid function: effect of kinase inhibitors, long-acting β(2)-adrenoceptor [corrected] agonist and glucocorticoid receptor ligands.

Rider CF, Shah S, Miller-Larsson A, Giembycz MA, Newton R.

PLoS One. 2015 Jan 27;10(1):e0116773. doi: 10.1371/journal.pone.0116773. eCollection 2015. Erratum in: PLoS One. 2015;10(5):e0128728.


How have alternative bearings and modularity affected revision rates in total hip arthroplasty?

Mihalko WM, Wimmer MA, Pacione CA, Laurent MP, Murphy RF, Rider C.

Clin Orthop Relat Res. 2014 Dec;472(12):3747-58. doi: 10.1007/s11999-014-3816-2. Review.


Evaluating the additivity of perfluoroalkyl acids in binary combinations on peroxisome proliferator-activated receptor-α activation.

Wolf CJ, Rider CV, Lau C, Abbott BD.

Toxicology. 2014 Feb 28;316:43-54. doi: 10.1016/j.tox.2013.12.002. Epub 2013 Dec 26.


Mucosal delivery of antigen-coated nanoparticles to lungs confers protective immunity against tuberculosis infection in mice.

Stylianou E, Diogo GR, Pepponi I, van Dolleweerd C, Arias MA, Locht C, Rider CC, Sibley L, Cutting SM, Loxley A, Ma JK, Reljic R.

Eur J Immunol. 2014 Feb;44(2):440-9.


Induction of regulator of G-protein signaling 2 expression by long-acting β2-adrenoceptor agonists and glucocorticoids in human airway epithelial cells.

Holden NS, George T, Rider CF, Chandrasekhar A, Shah S, Kaur M, Johnson M, Siderovski DP, Leigh R, Giembycz MA, Newton R.

J Pharmacol Exp Ther. 2014 Jan;348(1):12-24. doi: 10.1124/jpet.113.204586. Epub 2013 Oct 25.


Cumulative risk: toxicity and interactions of physical and chemical stressors.

Rider CV, Boekelheide K, Catlin N, Gordon CJ, Morata T, Selgrade MK, Sexton K, Simmons JE.

Toxicol Sci. 2014 Jan;137(1):3-11. doi: 10.1093/toxsci/kft228. Epub 2013 Oct 23.


Toxicity and carcinogenicity studies of Ginkgo biloba extract in rat and mouse: liver, thyroid, and nose are targets.

Rider CV, Nyska A, Cora MC, Kissling GE, Smith C, Travlos GS, Hejtmancik MR, Fomby LM, Colleton CA, Ryan MJ, Kooistra L, Morrison JP, Chan PC.

Toxicol Pathol. 2014 Jul;42(5):830-43. doi: 10.1177/0192623313501235. Epub 2013 Aug 19.


Modulation of transcriptional responses by poly(I:C) and human rhinovirus: effect of long-acting β₂-adrenoceptor agonists.

Rider CF, Miller-Larsson A, Proud D, Giembycz MA, Newton R.

Eur J Pharmacol. 2013 May 15;708(1-3):60-7. doi: 10.1016/j.ejphar.2013.02.056. Epub 2013 Mar 20.


Elevated transcription of the gene QSOX1 encoding quiescin Q6 sulfhydryl oxidase 1 in breast cancer.

Soloviev M, Esteves MP, Amiri F, Crompton MR, Rider CC.

PLoS One. 2013;8(2):e57327. doi: 10.1371/journal.pone.0057327. Epub 2013 Feb 27.


Unraveling the health effects of environmental mixtures: an NIEHS priority.

Carlin DJ, Rider CV, Woychik R, Birnbaum LS.

Environ Health Perspect. 2013 Jan;121(1):A6-8. No abstract available.


Glucocorticoid repression of inflammatory gene expression shows differential responsiveness by transactivation- and transrepression-dependent mechanisms.

King EM, Chivers JE, Rider CF, Minnich A, Giembycz MA, Newton R.

PLoS One. 2013;8(1):e53936. doi: 10.1371/journal.pone.0053936. Epub 2013 Jan 14.


Relationship of therapeutic recreation inpatient rehabilitation interventions and patient characteristics to outcomes following spinal cord injury: the SCIRehab project.

Cahow C, Gassaway J, Rider C, Joyce JP, Bogenschutz A, Edens K, Kreider SE, Whiteneck G.

J Spinal Cord Med. 2012 Nov;35(6):547-64. doi: 10.1179/2045772312Y.0000000066. Erratum in: J Spinal Cord Med. 2013 Mar;36(2):172. Bogenshutz, Andrew [corrected to Bogenschutz, Andrew].


Hepatocellular carcinomas in B6C3F1 mice treated with Ginkgo biloba extract for two years differ from spontaneous liver tumors in cancer gene mutations and genomic pathways.

Hoenerhoff MJ, Pandiri AR, Snyder SA, Hong HH, Ton TV, Peddada S, Shockley K, Witt K, Chan P, Rider C, Kooistra L, Nyska A, Sills RC.

Toxicol Pathol. 2013 Aug;41(6):826-41. doi: 10.1177/0192623312467520. Epub 2012 Dec 21.


Mixtures research at NIEHS: an evolving program.

Rider CV, Carlin DJ, Devito MJ, Thompson CL, Walker NJ.

Toxicology. 2013 Nov 16;313(2-3):94-102. doi: 10.1016/j.tox.2012.10.017. Epub 2012 Nov 9.


Evaluation of N-butylbenzenesulfonamide (NBBS) neurotoxicity in Sprague-Dawley male rats following 27-day oral exposure.

Rider CV, Janardhan KS, Rao D, Morrison JP, McPherson CA, Harry GJ.

Neurotoxicology. 2012 Dec;33(6):1528-35. doi: 10.1016/j.neuro.2012.07.002. Epub 2012 Jul 20.


Incorporating nonchemical stressors into cumulative risk assessments.

Rider CV, Dourson ML, Hertzberg RC, Mumtaz MM, Price PS, Simmons JE.

Toxicol Sci. 2012 May;127(1):10-7. doi: 10.1093/toxsci/kfs088. Epub 2012 Feb 17.


Women, Men, and Love Magic in Late Medieval English Pastoral Manuals.

Rider C.

Magic Ritual Witch. 2012 Winter;7(2):190-211. No abstract available.


β2-Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoids.

Holden NS, Bell MJ, Rider CF, King EM, Gaunt DD, Leigh R, Johnson M, Siderovski DP, Heximer SP, Giembycz MA, Newton R.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19713-8. doi: 10.1073/pnas.1110226108. Epub 2011 Nov 11.


Corticosteroid-induced gene expression in allergen-challenged asthmatic subjects taking inhaled budesonide.

Kelly MM, King EM, Rider CF, Gwozd C, Holden NS, Eddleston J, Zuraw B, Leigh R, O'Byrne PM, Newton R.

Br J Pharmacol. 2012 Mar;165(6):1737-1747. doi: 10.1111/j.1476-5381.2011.01620.x.


Inflammatory stimuli inhibit glucocorticoid-dependent transactivation in human pulmonary epithelial cells: rescue by long-acting beta2-adrenoceptor agonists.

Rider CF, King EM, Holden NS, Giembycz MA, Newton R.

J Pharmacol Exp Ther. 2011 Sep;338(3):860-9. doi: 10.1124/jpet.111.181016. Epub 2011 May 27.


Medical Magic and the Church in Thirteenth-Century England.

Rider C.

Soc Hist Med. 2011 Apr 1;24(1):92-107. No abstract available.

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