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Items: 20

1.

Novel H6PDH mutations in two girls with premature adrenarche: 'apparent' and 'true' CRD can be differentiated by urinary steroid profiling.

Lavery GG, Idkowiak J, Sherlock M, Bujalska I, Ride JP, Saqib K, Hartmann MF, Hughes B, Wudy SA, De Schepper J, Arlt W, Krone N, Shackleton CH, Walker EA, Stewart PM.

Eur J Endocrinol. 2013 Feb 1;168(2):K19-26. doi: 10.1530/EJE-12-0628. Print 2013 Feb.

2.

Cortisone-reductase deficiency associated with heterozygous mutations in 11beta-hydroxysteroid dehydrogenase type 1.

Lawson AJ, Walker EA, Lavery GG, Bujalska IJ, Hughes B, Arlt W, Stewart PM, Ride JP.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4111-6. doi: 10.1073/pnas.1014934108. Epub 2011 Feb 15.

3.

Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers.

Veli├ža P, Davies NJ, Rocha PP, Schrewe H, Ride JP, Bunce CM.

Mol Cancer. 2009 Dec 14;8:121. doi: 10.1186/1476-4598-8-121. Erratum in: Mol Cancer. 2010;9:21.

4.

Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia.

Khanim FL, Hayden RE, Birtwistle J, Lodi A, Tiziani S, Davies NJ, Ride JP, Viant MR, Gunther UL, Mountford JC, Schrewe H, Green RM, Murray JA, Drayson MT, Bunce CM.

PLoS One. 2009 Dec 7;4(12):e8147. doi: 10.1371/journal.pone.0008147.

5.

Characterization of two novel aldo-keto reductases from Arabidopsis: expression patterns, broad substrate specificity, and an open active-site structure suggest a role in toxicant metabolism following stress.

Simpson PJ, Tantitadapitak C, Reed AM, Mather OC, Bunce CM, White SA, Ride JP.

J Mol Biol. 2009 Sep 18;392(2):465-80. doi: 10.1016/j.jmb.2009.07.023. Epub 2009 Jul 15.

PMID:
19616008
6.

Mutations of key hydrophobic surface residues of 11 beta-hydroxysteroid dehydrogenase type 1 increase solubility and monodispersity in a bacterial expression system.

Lawson AJ, Walker EA, White SA, Dafforn TR, Stewart PM, Ride JP.

Protein Sci. 2009 Jul;18(7):1552-63. doi: 10.1002/pro.150.

7.

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

Davies NJ, Hayden RE, Simpson PJ, Birtwistle J, Mayer K, Ride JP, Bunce CM.

Cancer Res. 2009 Jun 1;69(11):4769-75. doi: 10.1158/0008-5472.CAN-08-4533.

8.

The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.

Birtwistle J, Hayden RE, Khanim FL, Green RM, Pearce C, Davies NJ, Wake N, Schrewe H, Ride JP, Chipman JK, Bunce CM.

Mutat Res. 2009 Mar 9;662(1-2):67-74. doi: 10.1016/j.mrfmmm.2008.12.010. Epub 2008 Dec 31.

PMID:
19162045
9.

Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency.

Lavery GG, Walker EA, Tiganescu A, Ride JP, Shackleton CH, Tomlinson JW, Connell JM, Ray DW, Biason-Lauber A, Malunowicz EM, Arlt W, Stewart PM.

J Clin Endocrinol Metab. 2008 Oct;93(10):3827-32. doi: 10.1210/jc.2008-0743. Epub 2008 Jul 15.

10.

11beta-Hydroxysteroid Dehydrogenase Type 1 Regulation by Intracellular Glucose 6-Phosphate Provides Evidence for a Novel Link between Glucose Metabolism and Hypothalamo-Pituitary-Adrenal Axis Function.

Walker EA, Ahmed A, Lavery GG, Tomlinson JW, Kim SY, Cooper MS, Ride JP, Hughes BA, Shackleton CH, McKiernan P, Elias E, Chou JY, Stewart PM.

J Biol Chem. 2007 Sep 14;282(37):27030-6. Epub 2007 Jun 22.

11.

Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study.

Arlt W, Walker EA, Draper N, Ivison HE, Ride JP, Hammer F, Chalder SM, Borucka-Mankiewicz M, Hauffa BP, Malunowicz EM, Stewart PM, Shackleton CH.

Lancet. 2004 Jun 26;363(9427):2128-35.

PMID:
15220035
12.
13.

The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs.

Desmond JC, Mountford JC, Drayson MT, Walker EA, Hewison M, Ride JP, Luong QT, Hayden RE, Vanin EF, Bunce CM.

Cancer Res. 2003 Jan 15;63(2):505-12.

14.

Functional expression, characterization, and purification of the catalytic domain of human 11-beta -hydroxysteroid dehydrogenase type 1.

Walker EA, Clark AM, Hewison M, Ride JP, Stewart PM.

J Biol Chem. 2001 Jun 15;276(24):21343-50. Epub 2001 Apr 6.

15.

S-protein mutants indicate a functional role for SBP in the self-incompatibility reaction of Papaver rhoeas.

Jordan ND, Kakeda K, Conner A, Ride JP, Franklin-Tong VE, Franklin FC.

Plant J. 1999 Oct;20(1):119-25.

16.

Analysis of Arabidopsis genome sequence reveals a large new gene family in plants.

Ride JP, Davies EM, Franklin FC, Marshall DF.

Plant Mol Biol. 1999 Mar;39(5):927-32.

PMID:
10344198
17.

Identification of residues in a hydrophilic loop of the Papaver rhoeas S protein that play a crucial role in recognition of incompatible pollen.

Kakeda K, Jordan ND, Conner A, Ride JP, Franklin-Tong VE, Franklin FC.

Plant Cell. 1998 Oct;10(10):1723-32.

18.

Molecular analysis of two functional homologues of the S3 allele of the Papaver rhoeas self-incompatibility gene isolated from different populations.

Walker EA, Ride JP, Kurup S, Franklin-Tong VE, Lawrence MJ, Franklin FC.

Plant Mol Biol. 1996 Mar;30(5):983-94.

PMID:
8639756
19.

Cloning and expression of a distinctive class of self-incompatibility (S) gene from Papaver rhoeas L.

Foote HC, Ride JP, Franklin-Tong VE, Walker EA, Lawrence MJ, Franklin FC.

Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2265-9.

20.

Estimation of Absidia ramosa infection in the brain and kidneys of cortisone-treated mice by chitin assay.

White LO, Newham HC, Ride JP.

Mycopathologia. 1978 Aug 10;63(3):177-9.

PMID:
692633

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