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A Qualitative Study of Increased Pediatric Reutilization After a Postdischarge Home Nurse Visit.

Riddle SW, Sherman SN, Moore MJ, Loechtenfeldt AM, Tubbs-Cooley HL, Gold JM, Wade-Murphy S, Beck AF, Statile AM, Shah SS, Simmons JM; H2O study group.

J Hosp Med. 2020 Mar 18;15:E1-E8. doi: 10.12788/jhm.3370. [Epub ahead of print]


Paediatric clinical and social concerns identified by home visit nurses in the immediate postdischarge period.

Tubbs-Cooley HL, Riddle SW, Gold JM, Wade-Murphy S, Auger KA, Statile AM, Sucharew HS, Shah SS, Simmons JM, Pickler RH; H2O Study Group.

J Adv Nurs. 2020 Mar 4. doi: 10.1111/jan.14341. [Epub ahead of print]


Exposure to Closed Loop Barriers Using Virtual Reality.

Lanning M, Shen J, Wasser D, Riddle S, Agustin B, Hood K, Naranjo D.

J Diabetes Sci Technol. 2020 Feb 5:1932296820902771. doi: 10.1177/1932296820902771. [Epub ahead of print]


Complex Fetal Care Cases: Fetoscopic Myelomeningocele Repair.

Riddle S, Peiro JL, Lim FY, Kingma PS.

Neoreviews. 2020 Jan;21(1):e66-e71. doi: 10.1542/neo.21-1-e66. No abstract available.


Emergency department utilization among pediatric spina bifida patients.

Riddle S, Meinzen-Derr J, Tabangin M, Woodward J, Wiley S.

J Pediatr Rehabil Med. 2019;12(4):375-381. doi: 10.3233/PRM-180561.


Reply to Letter to the Editor by Frank Nice.

Nommsen-Rivers L, King E, Wagner E, Riddle S, Ward L, Thompson A.

J Hum Lact. 2020 Feb;36(1):196. doi: 10.1177/0890334419879116. Epub 2019 Oct 9. No abstract available.


Observing the 3D Chemical Bond and its Energy Distribution in a Projected Space.

Wilson TR, Rajivmoorthy M, Goss J, Riddle S, Eberhart ME.

Chemphyschem. 2019 Dec 16;20(24):3289-3305. doi: 10.1002/cphc.201900962. Epub 2019 Dec 4.


Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension.

Hu CJ, Poth JM, Zhang H, Flockton A, Laux A, Kumar S, McKeon B, Mouradian G, Li M, Riddle S, Pugliese SC, Brown RD, Wallace EM, Graham BB, Frid MG, Stenmark KR.

Eur Respir J. 2019 Dec 12;54(6). pii: 1900378. doi: 10.1183/13993003.00378-2019. Print 2019 Dec.


Recommended quality measures for health-system pharmacy: 2019 update from the Pharmacy Accountability Measures Work Group.

Andrawis M, Ellison LTCC, Riddle S, Mahan KC, Collins CD, Brummond P, Carmichael J.

Am J Health Syst Pharm. 2019 Jun 3;76(12):874-887. doi: 10.1093/ajhp/zxz069.


Morbidity and cost burden of prenatal myelomeningocele repair.

Riddle S, Huddle R, Lim FY, Stevenson C, Dean K, Sparling K, Fenchel M, Schibler K.

J Matern Fetal Neonatal Med. 2019 Jul 25:1-7. doi: 10.1080/14767058.2019.1645827. [Epub ahead of print]


In Silico Examination of Initiation of Long-Acting Insulin Analogs Toujeo Compared to Lantus Under 3 Dosing Titration Rules in Virtual Type 2 Diabetes Subjects.

Sieber J, Weinheimer M, Kongable G, Riddle S, Chang YY, Flacke F.

J Diabetes Sci Technol. 2019 Jul 9:1932296819861586. doi: 10.1177/1932296819861586. [Epub ahead of print]


AMPK directly activates mTORC2 to promote cell survival during acute energetic stress.

Kazyken D, Magnuson B, Bodur C, Acosta-Jaquez HA, Zhang D, Tong X, Barnes TM, Steinl GK, Patterson NE, Altheim CH, Sharma N, Inoki K, Cartee GD, Bridges D, Yin L, Riddle SM, Fingar DC.

Sci Signal. 2019 Jun 11;12(585). pii: eaav3249. doi: 10.1126/scisignal.aav3249.


Feasibility and Acceptability of Metformin to Augment Low Milk Supply: A Pilot Randomized Controlled Trial.

Nommsen-Rivers L, Thompson A, Riddle S, Ward L, Wagner E, King E.

J Hum Lact. 2019 May;35(2):261-271. doi: 10.1177/0890334418819465. Epub 2019 Jan 10.


The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists.

Bodur C, Kazyken D, Huang K, Ekim Ustunel B, Siroky KA, Tooley AS, Gonzalez IE, Foley DH, Acosta-Jaquez HA, Barnes TM, Steinl GK, Cho KW, Lumeng CN, Riddle SM, Myers MG Jr, Fingar DC.

EMBO J. 2018 Jan 4;37(1):19-38. doi: 10.15252/embj.201696164. Epub 2017 Nov 17.


Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.

Zhang H, Wang D, Li M, Plecitá-Hlavatá L, D'Alessandro A, Tauber J, Riddle S, Kumar S, Flockton A, McKeon BA, Frid MG, Reisz JA, Caruso P, El Kasmi KC, Ježek P, Morrell NW, Hu CJ, Stenmark KR.

Circulation. 2017 Dec 19;136(25):2468-2485. doi: 10.1161/CIRCULATIONAHA.117.028069. Epub 2017 Sep 26.


Re: "ABM Clinical Protocol #3: Supplementary Feedings in the Healthy Term Breastfed Neonate, Revised 2017" by Kellams et al. (Breastfeed Med 2017;12:188-198).

Ward L, Nommsen-Rivers LA, Riddle S.

Breastfeed Med. 2017 Nov;12(9):574-575. doi: 10.1089/bfm.2017.0081. Epub 2017 Aug 7. No abstract available.


Analysis of the Accuracy and Performance of a Continuous Glucose Monitoring Sensor Prototype: An In-Silico Study Using the UVA/PADOVA Type 1 Diabetes Simulator.

Breton MD, Hinzmann R, Campos-Nañez E, Riddle S, Schoemaker M, Schmelzeisen-Redeker G.

J Diabetes Sci Technol. 2017 May;11(3):545-552. doi: 10.1177/1932296816680633. Epub 2016 Dec 13.


TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.

Kumar R, Mickael C, Kassa B, Gebreab L, Robinson JC, Koyanagi DE, Sanders L, Barthel L, Meadows C, Fox D, Irwin D, Li M, McKeon BA, Riddle S, Dale Brown R, Morgan LE, Evans CM, Hernandez-Saavedra D, Bandeira A, Maloney JP, Bull TM, Janssen WJ, Stenmark KR, Tuder RM, Graham BB.

Nat Commun. 2017 May 30;8:15494. doi: 10.1038/ncomms15494.


A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension.

Pugliese SC, Kumar S, Janssen WJ, Graham BB, Frid MG, Riddle SR, El Kasmi KC, Stenmark KR.

J Immunol. 2017 Jun 15;198(12):4802-4812. doi: 10.4049/jimmunol.1601692. Epub 2017 May 12.


Low milk supply and the pediatrician.

Riddle SW, Nommsen-Rivers LA.

Curr Opin Pediatr. 2017 Apr;29(2):249-256. doi: 10.1097/MOP.0000000000000468. Review.


Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.

Li M, Riddle S, Zhang H, D'Alessandro A, Flockton A, Serkova NJ, Hansen KC, Moldovan R, McKeon BA, Frid M, Kumar S, Li H, Liu H, Caánovas A, Medrano JF, Thomas MG, Iloska D, Plecitá-Hlavatá L, Ježek P, Pullamsetti S, Fini MA, El Kasmi KC, Zhang Q, Stenmark KR.

Circulation. 2016 Oct 11;134(15):1105-1121. Epub 2016 Aug 25. Erratum in: Circulation. 2019 Jan 8;139(2):e1. Moldvan, Radu [corrected to Moldovan, Radu].


A Case Control Study of Diabetes During Pregnancy and Low Milk Supply.

Riddle SW, Nommsen-Rivers LA.

Breastfeed Med. 2016 Mar;11(2):80-5. doi: 10.1089/bfm.2015.0120. Epub 2016 Feb 9.


Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension.

Newman JH, Holt TN, Cogan JD, Womack B, Phillips JA 3rd, Li C, Kendall Z, Stenmark KR, Thomas MG, Brown RD, Riddle SR, West JD, Hamid R.

Nat Commun. 2015 Apr 15;6:6863. doi: 10.1038/ncomms7863.


Pharmacological targeting of the pseudokinase Her3.

Xie T, Lim SM, Westover KD, Dodge ME, Ercan D, Ficarro SB, Udayakumar D, Gurbani D, Tae HS, Riddle SM, Sim T, Marto JA, Jänne PA, Crews CM, Gray NS.

Nat Chem Biol. 2014 Dec;10(12):1006-12. doi: 10.1038/nchembio.1658. Epub 2014 Oct 19.


LRRK2 kinase activity and biology are not uniformly predicted by its autophosphorylation and cellular phosphorylation site status.

Reynolds A, Doggett EA, Riddle SM, Lebakken CS, Nichols RJ.

Front Mol Neurosci. 2014 Jun 24;7:54. doi: 10.3389/fnmol.2014.00054. eCollection 2014.


Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.

El Kasmi KC, Pugliese SC, Riddle SR, Poth JM, Anderson AL, Frid MG, Li M, Pullamsetti SS, Savai R, Nagel MA, Fini MA, Graham BB, Tuder RM, Friedman JE, Eltzschig HK, Sokol RJ, Stenmark KR.

J Immunol. 2014 Jul 15;193(2):597-609. doi: 10.4049/jimmunol.1303048. Epub 2014 Jun 13.


Parkinson disease-associated mutation R1441H in LRRK2 prolongs the "active state" of its GTPase domain.

Liao J, Wu CX, Burlak C, Zhang S, Sahm H, Wang M, Zhang ZY, Vogel KW, Federici M, Riddle SM, Nichols RJ, Liu D, Cookson MR, Stone TA, Hoang QQ.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4055-60. doi: 10.1073/pnas.1323285111. Epub 2014 Mar 3.


Threshold levels of ABL tyrosine kinase inhibitors retained in chronic myeloid leukemia cells determine their commitment to apoptosis.

O'Hare T, Eide CA, Agarwal A, Adrian LT, Zabriskie MS, Mackenzie RJ, Latocha DH, Johnson KJ, You H, Luo J, Riddle SM, Marks BD, Vogel KW, Koop DR, Apgar J, Tyner JW, Deininger MW, Druker BJ.

Cancer Res. 2013 Jun 1;73(11):3356-70. doi: 10.1158/0008-5472.CAN-12-3904. Epub 2013 Apr 10.


The adventitia: essential regulator of vascular wall structure and function.

Stenmark KR, Yeager ME, El Kasmi KC, Nozik-Grayck E, Gerasimovskaya EV, Li M, Riddle SR, Frid MG.

Annu Rev Physiol. 2013;75:23-47. doi: 10.1146/annurev-physiol-030212-183802. Epub 2012 Dec 3. Review.


Pharmacological inhibition of LRRK2 cellular phosphorylation sites provides insight into LRRK2 biology.

Zhao J, Hermanson SB, Carlson CB, Riddle SM, Vogel KW, Bi K, Nichols RJ.

Biochem Soc Trans. 2012 Oct;40(5):1158-62. Review.


Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation.

Hermanson SB, Carlson CB, Riddle SM, Zhao J, Vogel KW, Nichols RJ, Bi K.

PLoS One. 2012;7(8):e43580. doi: 10.1371/journal.pone.0043580. Epub 2012 Aug 28.


Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent.

Ni J, Liu Q, Xie S, Carlson C, Von T, Vogel K, Riddle S, Benes C, Eck M, Roberts T, Gray N, Zhao J.

Cancer Discov. 2012 May;2(5):425-33. doi: 10.1158/2159-8290.CD-12-0003. Epub 2012 Apr 12.


Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension.

Anwar A, Li M, Frid MG, Kumar B, Gerasimovskaya EV, Riddle SR, McKeon BA, Thukaram R, Meyrick BO, Fini MA, Stenmark KR.

Am J Physiol Lung Cell Mol Physiol. 2012 Jul 1;303(1):L1-L11. doi: 10.1152/ajplung.00050.2012. Epub 2012 May 11.


Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change.

Stenmark KR, Frid MG, Yeager M, Li M, Riddle S, McKinsey T, El Kasmi KC.

Pulm Circ. 2012 Jan-Mar;2(1):3-14. doi: 10.4103/2045-8932.94817.


Detection of allosteric kinase inhibitors by displacement of active site probes.

Lebakken CS, Reichling LJ, Ellefson JM, Riddle SM.

J Biomol Screen. 2012 Jul;17(6):813-21. doi: 10.1177/1087057112439889. Epub 2012 Mar 26.


Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics.

Liu Q, Kirubakaran S, Hur W, Niepel M, Westover K, Thoreen CC, Wang J, Ni J, Patricelli MP, Vogel K, Riddle S, Waller DL, Traynor R, Sanda T, Zhao Z, Kang SA, Zhao J, Look AT, Sorger PK, Sabatini DM, Gray NS.

J Biol Chem. 2012 Mar 23;287(13):9742-52. doi: 10.1074/jbc.M111.304485. Epub 2012 Jan 5.


A substrate-independent TR-FRET histone deacetylase inhibitor assay.

Marks BD, Fakhoury SA, Frazee WJ, Eliason HC, Riddle SM.

J Biomol Screen. 2011 Dec;16(10):1247-53. doi: 10.1177/1087057111422102. Epub 2011 Sep 21.


Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension.

Li M, Riddle SR, Frid MG, El Kasmi KC, McKinsey TA, Sokol RJ, Strassheim D, Meyrick B, Yeager ME, Flockton AR, McKeon BA, Lemon DD, Horn TR, Anwar A, Barajas C, Stenmark KR.

J Immunol. 2011 Sep 1;187(5):2711-22. doi: 10.4049/jimmunol.1100479. Epub 2011 Aug 3.


The adventitia: Essential role in pulmonary vascular remodeling.

Stenmark KR, Nozik-Grayck E, Gerasimovskaya E, Anwar A, Li M, Riddle S, Frid M.

Compr Physiol. 2011 Jan;1(1):141-61. doi: 10.1002/cphy.c090017. Review.


Introducing W.A.T.E.R.S.: a workflow for the alignment, taxonomy, and ecology of ribosomal sequences.

Hartman AL, Riddle S, McPhillips T, Ludäscher B, Eisen JA.

BMC Bioinformatics. 2010 Jun 12;11:317. doi: 10.1186/1471-2105-11-317.


Prostacyclin inhibits IFN-gamma-stimulated cytokine expression by reduced recruitment of CBP/p300 to STAT1 in a SOCS-1-independent manner.

Strassheim D, Riddle SR, Burke DL, Geraci MW, Stenmark KR.

J Immunol. 2009 Dec 1;183(11):6981-8. doi: 10.4049/jimmunol.0901045. Epub 2009 Nov 13.


PI3K, Rho, and ROCK play a key role in hypoxia-induced ATP release and ATP-stimulated angiogenic responses in pulmonary artery vasa vasorum endothelial cells.

Woodward HN, Anwar A, Riddle S, Taraseviciene-Stewart L, Fragoso M, Stenmark KR, Gerasimovskaya EV.

Am J Physiol Lung Cell Mol Physiol. 2009 Nov;297(5):L954-64. doi: 10.1152/ajplung.00038.2009. Epub 2009 Aug 14.


Development and applications of a broad-coverage, TR-FRET-based kinase binding assay platform.

Lebakken CS, Riddle SM, Singh U, Frazee WJ, Eliason HC, Gao Y, Reichling LJ, Marks BD, Vogel KW.

J Biomol Screen. 2009 Sep;14(8):924-35. doi: 10.1177/1087057109339207. Epub 2009 Jun 29.


Leucine-rich repeat kinase 2 mutants I2020T and G2019S exhibit altered kinase inhibitor sensitivity.

Reichling LJ, Riddle SM.

Biochem Biophys Res Commun. 2009 Jun 26;384(2):255-8. doi: 10.1016/j.bbrc.2009.04.098. Epub 2009 May 3.


Source apportionment of fine (PM1.8) and ultrafine (PM0.1) airborne particulate matter during a severe winter pollution episode.

Kleeman MJ, Riddle SG, Robert MA, Jakober CA, Fine PM, Hays MD, Schauer JJ, Hannigan MP.

Environ Sci Technol. 2009 Jan 15;43(2):272-9.


Investigation of leucine-rich repeat kinase 2 : enzymological properties and novel assays.

Anand VS, Reichling LJ, Lipinski K, Stochaj W, Duan W, Kelleher K, Pungaliya P, Brown EL, Reinhart PH, Somberg R, Hirst WD, Riddle SM, Braithwaite SP.

FEBS J. 2009 Jan;276(2):466-78. doi: 10.1111/j.1742-4658.2008.06789.x.


Size-resolved source apportionment of airborne particle mass in a roadside environment.

Riddle SG, Robert MA, Jakober CA, Hannigan MP, Kleeman MJ.

Environ Sci Technol. 2008 Sep 1;42(17):6580-6.


Size distribution of particle-phase molecular markers during a severe winter pollution episode.

Kleeman MJ, Riddle SG, Jakober CA.

Environ Sci Technol. 2008 Sep 1;42(17):6469-75.


The breastfeeding mother and the pediatrician.

Geraghty SR, Riddle SW, Shaikh U.

J Hum Lact. 2008 Aug;24(3):335-9. doi: 10.1177/0890334408321091.


Carbonyl emissions from gasoline and diesel motor vehicles.

Jakober CA, Robert MA, Riddle SG, Destaillats H, Charles MJ, Green PG, Kleeman MJ.

Environ Sci Technol. 2008 Jul 1;42(13):4697-703.


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