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Items: 48

1.

Suppression of Hepatic CYP3A4 Expression and Activity by 3-Methylcholanthrene in Humanized PXR-CAR-CYP3A4/3A7 Mice.

Crosby M, Riddick DS.

Drug Metab Dispos. 2019 Mar;47(3):279-282. doi: 10.1124/dmd.118.084509. Epub 2018 Dec 20.

PMID:
30573465
2.

Downregulation of cytochrome P450 2C8 by 3-methylcholanthrene in human hepatocellular carcinoma cell lines.

Utgikar R, Riddick DS.

Can J Physiol Pharmacol. 2017 Jun;95(6):768-771. doi: 10.1139/cjpp-2017-0014. Epub 2017 Apr 6.

PMID:
28384415
3.

Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase.

Hunter SR, Vonk A, Mullen Grey AK, Riddick DS.

Drug Metab Dispos. 2017 Feb;45(2):118-129. doi: 10.1124/dmd.116.073833. Epub 2016 Nov 16.

PMID:
27856527
4.

Loss of hepatic aryl hydrocarbon receptor protein in adrenalectomized rats does not involve altered levels of the receptor's cytoplasmic chaperones.

Lee C, Mullen Grey AK, Riddick DS.

Can J Physiol Pharmacol. 2013 Dec;91(12):1154-7. doi: 10.1139/cjpp-2013-0238. Epub 2013 Aug 16.

5.

Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism.

Lee C, Ding X, Riddick DS.

Drug Metab Dispos. 2013 Oct;41(10):1782-6. doi: 10.1124/dmd.113.052993. Epub 2013 Jul 11.

6.

The role of cytochrome P450-dependent metabolism in the regulation of mouse hepatic growth hormone signaling components and target genes by 3-methylcholanthrene.

Lee C, Ding X, Riddick DS.

Drug Metab Dispos. 2013 Feb;41(2):457-65. doi: 10.1124/dmd.112.048835. Epub 2012 Nov 20.

7.

Induction of multidrug resistance transporter ABCG2 by prolactin in human breast cancer cells.

Wu AM, Dalvi P, Lu X, Yang M, Riddick DS, Matthews J, Clevenger CV, Ross DD, Harper PA, Ito S.

Mol Pharmacol. 2013 Feb;83(2):377-88. doi: 10.1124/mol.112.082362. Epub 2012 Nov 13.

PMID:
23150485
8.

NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology.

Riddick DS, Ding X, Wolf CR, Porter TD, Pandey AV, Zhang QY, Gu J, Finn RD, Ronseaux S, McLaughlin LA, Henderson CJ, Zou L, Fl├╝ck CE.

Drug Metab Dispos. 2013 Jan;41(1):12-23. doi: 10.1124/dmd.112.048991. Epub 2012 Oct 19.

9.

Aryl hydrocarbon receptor-dependence of dioxin's effects on constitutive mouse hepatic cytochromes P450 and growth hormone signaling components.

Lee C, Riddick DS.

Can J Physiol Pharmacol. 2012 Oct;90(10):1354-63. doi: 10.1139/y2012-099. Epub 2012 Sep 14.

10.

The aryl hydrocarbon receptor pathway and the response to 3-methylcholanthrene are altered in the liver of adrenalectomized rats.

Mullen Grey AK, Riddick DS.

Drug Metab Dispos. 2011 Jan;39(1):83-91. doi: 10.1124/dmd.110.035584. Epub 2010 Sep 29.

PMID:
20881032
11.

Glucocorticoid and adrenalectomy effects on the rat aryl hydrocarbon receptor pathway depend on the dosing regimen and post-surgical time.

Mullen Grey AK, Riddick DS.

Chem Biol Interact. 2009 Dec 10;182(2-3):148-58. doi: 10.1016/j.cbi.2009.07.005. Epub 2009 Jul 16.

PMID:
19615983
12.

Cytochrome P450 2C11 5'-flanking region and promoter mediate in vivo suppression by 3-methylcholanthrene.

Sawaya RM, Riddick DS.

Drug Metab Dispos. 2008 Sep;36(9):1803-11. doi: 10.1124/dmd.108.020966. Epub 2008 Jun 4.

PMID:
18524872
13.

Cytochrome P450 2C11 5'-flanking region and promoter: regulation by aromatic hydrocarbons in vitro.

Sawaya RM, Riddick DS.

Toxicology. 2008 Jun 27;248(2-3):104-12. doi: 10.1016/j.tox.2008.03.011. Epub 2008 Mar 22.

PMID:
18440119
14.

Regulation of aryl hydrocarbon receptor expression and function by glucocorticoids in mouse hepatoma cells.

Bielefeld KA, Lee C, Riddick DS.

Drug Metab Dispos. 2008 Mar;36(3):543-51. Epub 2007 Dec 17.

PMID:
18086832
15.

Regulation of constitutive mouse hepatic cytochromes P450 and growth hormone signaling components by 3-methylcholanthrene.

Lee C, Hutson JR, Tzau VK, Riddick DS.

Drug Metab Dispos. 2006 Sep;34(9):1530-8. Epub 2006 Jun 16.

PMID:
16782765
16.

Regulating the regulator: factors that control levels and activity of the aryl hydrocarbon receptor.

Harper PA, Riddick DS, Okey AB.

Biochem Pharmacol. 2006 Jul 28;72(3):267-79. Epub 2006 Feb 20. Review.

PMID:
16488401
17.

Cancer chemotherapy and drug metabolism.

Riddick DS, Lee C, Ramji S, Chinje EC, Cowen RL, Williams KJ, Patterson AV, Stratford IJ, Morrow CS, Townsend AJ, Jounaidi Y, Chen CS, Su T, Lu H, Schwartz PS, Waxman DJ.

Drug Metab Dispos. 2005 Aug;33(8):1083-96.

PMID:
16049130
18.

Transcriptional suppression of cytochrome P450 genes by endogenous and exogenous chemicals.

Riddick DS, Lee C, Bhathena A, Timsit YE, Cheng PY, Morgan ET, Prough RA, Ripp SL, Miller KK, Jahan A, Chiang JY.

Drug Metab Dispos. 2004 Apr;32(4):367-75. Review.

PMID:
15039287
19.
20.
21.

Aromatic hydrocarbon receptor expression and function in liver of hypophysectomized male rats.

Timsit YE, Chia FS, Bhathena A, Riddick DS.

Toxicol Appl Pharmacol. 2002 Dec 1;185(2):136-45.

PMID:
12490138
22.

Suppression of cytochrome P450 2C11 by aromatic hydrocarbons: mechanistic insights from studies of the 5'-flanking region of the CYP2C11 gene.

Bhathena A, Lee C, Riddick DS.

Drug Metab Dispos. 2002 Dec;30(12):1385-92. Erratum in: Drug Metab Dispos. 2005 Dec;33(12):1927.

PMID:
12433808
23.
24.

Transcriptional suppression of cytochrome P450 2C11 gene expression by 3-methylcholanthrene.

Lee C, Riddick DS.

Biochem Pharmacol. 2000 Jun 1;59(11):1417-23.

PMID:
10751551
25.
26.

Lack of mechanism-based inactivation of rat hepatic microsomal cytochromes P450 by doxorubicin.

Di Re J, Lee C, Riddick DS.

Can J Physiol Pharmacol. 1999 Aug;77(8):589-97.

PMID:
10543722
27.

Glutathione S-transferases in wild-type and doxorubicin-resistant MCF-7 human breast cancer cell lines.

Wang K, Ramji S, Bhathena A, Lee C, Riddick DS.

Xenobiotica. 1999 Feb;29(2):155-70.

PMID:
10199592
28.

Role of glutathione S-transferases in the resistance of human colon cancer cell lines to doxorubicin.

Beaumont PO, Moore MJ, Ahmad K, Payne MM, Lee C, Riddick DS.

Cancer Res. 1998 Mar 1;58(5):947-55.

30.
31.

Regulation of constitutive rat hepatic cytochromes P450 by 3-methylcholanthrene.

Jones EJ, Riddick DS.

Xenobiotica. 1996 Oct;26(10):995-1012.

PMID:
8905915
32.

Lack of effect of methotrexate on the expression of constitutive hepatic cytochromes P450 in the male rat.

Cheung RL, Lee C, Jones EJ, Riddick DS.

Xenobiotica. 1996 May;26(5):503-14.

PMID:
8736062
33.

Modulation of the expression on constitutive rat hepatic cytochrome P450 isozymes by 5-fluorouracil.

Afsar A, Lee C, Riddick DS.

Can J Physiol Pharmacol. 1996 Feb;74(2):150-6.

PMID:
8723027
34.

Ah receptor role in TCDD toxicity: still some mysteries but no myth--a reply to the commentary by Dr. L.W.D. Weber and Dr. B.U. Stahl.

Okey AB, Riddick DS, Harper PA.

Toxicol Lett. 1995 Jan;75(1-3):249-54. Review. No abstract available.

PMID:
7863534
35.

Molecular biology of the aromatic hydrocarbon (dioxin) receptor.

Okey AB, Riddick DS, Harper PA.

Trends Pharmacol Sci. 1994 Jul;15(7):226-32. Review.

PMID:
7940984
36.
37.

The Ah receptor: mediator of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds.

Okey AB, Riddick DS, Harper PA.

Toxicol Lett. 1994 Jan;70(1):1-22. Review.

PMID:
8310450
38.

Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation.

Jellinck PH, Forkert PG, Riddick DS, Okey AB, Michnovicz JJ, Bradlow HL.

Biochem Pharmacol. 1993 Mar 9;45(5):1129-36.

PMID:
8384853
39.

Inactivation of cytochrome P450 and inhibition of ferrochelatase by analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine with 4-nonyl and 4-dodecyl substituents.

McCluskey SA, Riddick DS, Mackie JE, Kimmett SM, Whitney RA, Marks GS.

Can J Physiol Pharmacol. 1992 Aug;70(8):1069-74.

PMID:
1473038
40.

Porphyrinogenic effects in chick embryo liver cell culture of chloramphenicol analogues that are mechanism-based inactivators of cytochrome P-450.

Green-Thompson RP, Riddick DS, Mackie JE, Marks GS, Halpert JR.

Can J Physiol Pharmacol. 1991 Apr;69(4):526-30.

PMID:
2059915
43.
45.

Interaction of chemicals with cytochrome P-450: implications for the porphyrinogenicity of drugs.

Marks GS, McCluskey SA, Mackie JE, Riddick DS, James CA.

Clin Biochem. 1989 Jun;22(3):169-75.

PMID:
2736770
47.

Regulation of heme biosynthesis in chick embryo liver cells.

Marks GS, Mackie JE, McCluskey SA, Riddick DS.

Adv Exp Med Biol. 1989;271:123-33. Review.

PMID:
2486279
48.

Disruption of hepatic heme biosynthesis after interaction of xenobiotics with cytochrome P-450.

Marks GS, McCluskey SA, Mackie JE, Riddick DS, James CA.

FASEB J. 1988 Sep;2(12):2774-83. Review.

PMID:
3044903

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