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Items: 41


Spatiotemporal immune zonation of the human kidney.

Stewart BJ, Ferdinand JR, Young MD, Mitchell TJ, Loudon KW, Riding AM, Richoz N, Frazer GL, Staniforth JUL, Vieira Braga FA, Botting RA, Popescu DM, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Polanski K, Efremova M, Green K, Del Castillo Velasco-Herrera M, Guzzo C, Collord G, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Lindsay S, Bajenoff M, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Behjati S, Clatworthy MR.

Science. 2019 Sep 27;365(6460):1461-1466. doi: 10.1126/science.aat5031.


The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma: development and evaluation using the ASSURE prospective clinical trial cohort.

Klatte T, Gallagher KM, Afferi L, Volpe A, Kroeger N, Ribback S, McNeill A, Riddick ACP, Armitage JN, 'Aho TF, Eisen T, Fife K, Bex A, Pantuck AJ, Stewart GD.

BMC Med. 2019 Oct 3;17(1):182. doi: 10.1186/s12916-019-1419-1.


Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.

Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ, Ferdinand JR, Collord G, Botting RA, Popescu DM, Loudon KW, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Del Castillo Velasco-Herrera M, Guzzo C, Richoz N, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Maxwell PH, Lindsay S, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Clatworthy M, Behjati S.

Science. 2018 Aug 10;361(6402):594-599. doi: 10.1126/science.aat1699.


Prognostic effect of cytoreductive nephrectomy in synchronous metastatic renal cell carcinoma: a comparative study using inverse probability of treatment weighting.

Klatte T, Fife K, Welsh SJ, Sachdeva M, Armitage JN, 'Aho T, Riddick AC, Matakidou A, Eisen T, Stewart GD.

World J Urol. 2018 Mar;36(3):417-425. doi: 10.1007/s00345-017-2154-x. Epub 2017 Dec 18.


Management of a Renal Mass in a Solitary Kidney: To Freeze or To Cut?

Klatte T, Riddick ACP, Stewart GD.

Eur Urol. 2018 Feb;73(2):260-261. doi: 10.1016/j.eururo.2017.09.023. Epub 2017 Oct 9. No abstract available.


Reduced Contractility and Motility of Prostatic Cancer-Associated Fibroblasts after Inhibition of Heat Shock Protein 90.

Henke A, Franco OE, Stewart GD, Riddick AC, Katz E, Hayward SW, Thomson AA.

Cancers (Basel). 2016 Aug 24;8(9). pii: E77. doi: 10.3390/cancers8090077.


Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer.

Stewart GD, O'Mahony FC, Laird A, Eory L, Lubbock AL, Mackay A, Nanda J, O'Donnell M, Mullen P, McNeill SA, Riddick AC, Berney D, Bex A, Aitchison M, Overton IM, Harrison DJ, Powles T.

Clin Cancer Res. 2015 Sep 15;21(18):4212-23. doi: 10.1158/1078-0432.CCR-15-0207. Epub 2015 May 26.


Translational research will fail without surgical leadership: SCOTRRCC a successful surgeon-led Nationwide translational research infrastructure in renal cancer.

Stewart GD, Riddick AC, Rae F, Marshall C, MacLeod L, O'Mahony FC, Laird A, Alan McNeill S, O'Connor KM, O'Donnell M, Fineron P, McLaren DB, Aitchison M, Oades G, Hair J, Seywright M, Little B, Nairn R, Lamb G, Macleod T, Dunn I, Ramsey A, Campbell R, Leung S, McLornan L, Rahilly M, Wilson I, Pollock AM, Harrison DJ.

Surgeon. 2015 Aug;13(4):181-6. doi: 10.1016/j.surge.2015.03.001. Epub 2015 Apr 30.


Matched-pair analysis of open versus laparoscopic nephroureterectomy for upper urinary tract urothelial cell carcinoma.

Blackmur JP, Stewart GD, Egong EA, Cutress ML, Tolley DA, Riddick AC, McNeill SA.

Urol Int. 2015;94(2):156-62. doi: 10.1159/000364833. Epub 2014 Sep 19.


Carbonic anhydrase 9 expression increases with vascular endothelial growth factor-targeted therapy and is predictive of outcome in metastatic clear cell renal cancer.

Stewart GD, O'Mahony FC, Laird A, Rashid S, Martin SA, Eory L, Lubbock AL, Nanda J, O'Donnell M, Mackay A, Mullen P, McNeill SA, Riddick AC, Aitchison M, Berney D, Bex A, Overton IM, Harrison DJ, Powles T.

Eur Urol. 2014 Nov;66(5):956-63. doi: 10.1016/j.eururo.2014.04.007. Epub 2014 May 10.


Renal cell carcinoma needle biopsy: sowing the seed for later complications?

Laird A, Couper CH, Glancy S, O'Donnell M, Riddick AC.

BMJ Case Rep. 2014 Apr 30;2014. pii: bcr2014203691. doi: 10.1136/bcr-2014-203691.


Matched pair analysis of laparoscopic versus open radical nephrectomy for the treatment of T3 renal cell carcinoma.

Laird A, Choy KC, Delaney H, Cutress ML, O'Connor KM, Tolley DA, McNeill SA, Stewart GD, Riddick AC.

World J Urol. 2015 Jan;33(1):25-32. doi: 10.1007/s00345-014-1280-y. Epub 2014 Mar 20.


Midterm oncological outcome and clinicopathological characteristics of anterior prostate cancers treated by endoscopic extraperitoneal radical prostatectomy.

Good DW, Stewart GD, Zakikhani P, Yuen H, Riddick AC, Bollina PR, O'Donnell M, Stolzenburg JU, McNeill SA.

World J Urol. 2014 Apr;32(2):393-8. doi: 10.1007/s00345-013-1114-3. Epub 2013 Jun 13.


A generation of laparoscopic nephrectomy: stage-specific surgical and oncologic outcomes for laparoscopic nephrectomy in a single center.

Laird A, Stewart GD, Zhong J, Ang WJ, Cutress ML, Riddick AC, McNeill SA, Tolley DA.

J Endourol. 2013 Aug;27(8):1008-14. doi: 10.1089/end.2012.0562.


Differential expression of prognostic proteomic markers in primary tumour, venous tumour thrombus and metastatic renal cell cancer tissue and correlation with patient outcome.

Laird A, O'Mahony FC, Nanda J, Riddick AC, O'Donnell M, Harrison DJ, Stewart GD.

PLoS One. 2013;8(4):e60483. doi: 10.1371/journal.pone.0060483. Epub 2013 Apr 5.


Endoscopic versus laparoscopic management of noninvasive upper tract urothelial carcinoma: 20-year single center experience.

Cutress ML, Stewart GD, Tudor EC, Egong EA, Wells-Cole S, Phipps S, Thomas BG, Riddick AC, McNeill SA, Tolley DA.

J Urol. 2013 Jun;189(6):2054-60. doi: 10.1016/j.juro.2012.12.006. Epub 2012 Dec 7.


Reduction of pro-tumorigenic activity of human prostate cancer-associated fibroblasts using Dlk1 or SCUBE1.

Orr B, Grace OC, Brown P, Riddick AC, Stewart GD, Franco OE, Hayward SW, Thomson AA.

Dis Model Mech. 2013 Mar;6(2):530-6. doi: 10.1242/dmm.010355. Epub 2012 Nov 7.


Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer.

Henke A, Grace OC, Ashley GR, Stewart GD, Riddick AC, Yeun H, O'Donnell M, Anderson RA, Thomson AA.

PLoS One. 2012;7(8):e42516. doi: 10.1371/journal.pone.0042516. Epub 2012 Aug 3.


mRNA profiling of the cancer degradome in oesophago-gastric adenocarcinoma.

Baren JP, Stewart GD, Stokes A, Gray K, Pennington CJ, O'Neill R, Deans DA, Paterson-Brown S, Riddick AC, Edwards DR, Fearon KC, Ross JA, Skipworth RJ.

Br J Cancer. 2012 Jun 26;107(1):143-9. doi: 10.1038/bjc.2012.239. Epub 2012 Jun 7.


Description and validation of a modular training system for laparoscopic nephrectomy.

Stewart GD, Phipps S, Little B, Leveckis J, Stolzenburg JU, Tolley DA, McNeill SA, Riddick AC.

J Endourol. 2012 Nov;26(11):1512-7. doi: 10.1089/end.2012.0096.


The use of automated quantitative analysis to evaluate epithelial-to-mesenchymal transition associated proteins in clear cell renal cell carcinoma.

O'Mahony FC, Faratian D, Varley J, Nanda J, Theodoulou M, Riddick AC, Harrison DJ, Stewart GD.

PLoS One. 2012;7(2):e31557. doi: 10.1371/journal.pone.0031557. Epub 2012 Feb 21.


The operative safety and oncological outcomes of laparoscopic nephrectomy for T3 renal cell cancer.

Stewart GD, Ang WJ, Laird A, Tolley DA, Riddick AC, McNeill SA.

BJU Int. 2012 Sep;110(6):884-90. doi: 10.1111/j.1464-410X.2011.10850.x. Epub 2012 Jan 30.


Long-term comparative outcomes of open versus laparoscopic nephroureterectomy for upper urinary tract urothelial-cell carcinoma after a median follow-up of 13 years*.

Stewart GD, Humphries KJ, Cutress ML, Riddick AC, McNeill SA, Tolley DA.

J Endourol. 2011 Aug;25(8):1329-35. doi: 10.1089/end.2011.0223. Epub 2011 Jul 11.


Identification of stromally expressed molecules in the prostate by tag-profiling of cancer-associated fibroblasts, normal fibroblasts and fetal prostate.

Orr B, Riddick AC, Stewart GD, Anderson RA, Franco OE, Hayward SW, Thomson AA.

Oncogene. 2012 Mar 1;31(9):1130-42. doi: 10.1038/onc.2011.312. Epub 2011 Aug 1.


A novel bovine model for training urological surgeons in laparoscopic radical nephrectomy.

Laird A, Stewart GD, Hou S, Tang B, McLornan ME, Riddick AC, McNeill SA.

J Endourol. 2011 Aug;25(8):1377-83. doi: 10.1089/end.2011.0060. Epub 2011 Jul 13.


What can molecular pathology contribute to the management of renal cell carcinoma?

Stewart GD, O'Mahony FC, Powles T, Riddick AC, Harrison DJ, Faratian D.

Nat Rev Urol. 2011 May;8(5):255-65. doi: 10.1038/nrurol.2011.43. Epub 2011 Apr 12. Review.


Utilizing mRNA extracted from small, archival formalin-fixed paraffin-embedded prostate samples for translational research: assessment of the effect of increasing sample age and storage temperature.

Stewart GD, Baird J, Rae F, Nanda J, Riddick AC, Harrison DJ.

Int Urol Nephrol. 2011 Dec;43(4):961-7. doi: 10.1007/s11255-011-9948-3. Epub 2011 Mar 30.


DNA strand breaks and hypoxia response inhibition mediate the radiosensitisation effect of nitric oxide donors on prostate cancer under varying oxygen conditions.

Stewart GD, Nanda J, Katz E, Bowman KJ, Christie JG, Brown DJ, McLaren DB, Riddick AC, Ross JA, Jones GD, Habib FK.

Biochem Pharmacol. 2011 Jan 15;81(2):203-10. doi: 10.1016/j.bcp.2010.09.022. Epub 2010 Oct 1.


Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia.

Orr B, Vanpoucke G, Grace OC, Smith L, Anderson RA, Riddick AC, Franco OE, Hayward SW, Thomson AA.

Prostate. 2011 Feb 15;71(3):305-17. doi: 10.1002/pros.21244. Epub 2010 Sep 1.


The relevance of a hypoxic tumour microenvironment in prostate cancer.

Stewart GD, Ross JA, McLaren DB, Parker CC, Habib FK, Riddick AC.

BJU Int. 2010 Jan;105(1):8-13. doi: 10.1111/j.1464-410X.2009.08921.x. Epub 2009 Nov 4. Review.


Analysis of hypoxia-associated gene expression in prostate cancer: lysyl oxidase and glucose transporter-1 expression correlate with Gleason score.

Stewart GD, Gray K, Pennington CJ, Edwards DR, Riddick AC, Ross JA, Habib FK.

Oncol Rep. 2008 Dec;20(6):1561-7.


NO-sulindac inhibits the hypoxia response of PC-3 prostate cancer cells via the Akt signalling pathway.

Stewart GD, Nanda J, Brown DJ, Riddick AC, Ross JA, Habib FK.

Int J Cancer. 2009 Jan 1;124(1):223-32. doi: 10.1002/ijc.23934.


Variation in dermcidin expression in a range of primary human tumours and in hypoxic/oxidatively stressed human cell lines.

Stewart GD, Skipworth RJ, Pennington CJ, Lowrie AG, Deans DA, Edwards DR, Habib FK, Riddick AC, Fearon KC, Ross JA.

Br J Cancer. 2008 Jul 8;99(1):126-32. doi: 10.1038/sj.bjc.6604458.


Laser-capture microdissection in prostate cancer research: establishment and validation of a powerful tool for the assessment of tumour-stroma interactions.

Shukla CJ, Pennington CJ, Riddick AC, Sethia KK, Ball RY, Edwards DR.

BJU Int. 2008 Mar;101(6):765-74. doi: 10.1111/j.1464-410X.2007.07372.x. Epub 2008 Jan 8.


Dermcidin expression confers a survival advantage in prostate cancer cells subjected to oxidative stress or hypoxia.

Stewart GD, Lowrie AG, Riddick AC, Fearon KC, Habib FK, Ross JA.

Prostate. 2007 Sep 1;67(12):1308-17.


Results of a definitive study are needed to provide guidance on the treatment of patients with screen-detected, 'low-grade' prostate cancer.

Stewart GD, Riddick AC, Bollina PR, McNeill SA.

BJU Int. 2006 Nov;98(5):944-5. No abstract available.


Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues.

Riddick AC, Shukla CJ, Pennington CJ, Bass R, Nuttall RK, Hogan A, Sethia KK, Ellis V, Collins AT, Maitland NJ, Ball RY, Edwards DR.

Br J Cancer. 2005 Jun 20;92(12):2171-80.


Bowel function after urinary diversion.

Riddick AC, Turner WH, Mills RD.

World J Urol. 2004 Sep;22(3):210-4. Epub 2004 Aug 31. Review.


Banking of fresh-frozen prostate tissue: methods, validation and use.

Riddick AC, Barker C, Sheriffs I, Bass R, Ellis V, Sethia KK, Edwards DR, Ball RY.

BJU Int. 2003 Mar;91(4):315-23; discussion 323-4.


Follow-up after carpal tunnel decompression - general practitioner surgery or hand clinic? A randomized prospective study.

Atherton WG, Faraj AA, Riddick AC, Davis TR.

J Hand Surg Br. 1999 Jun;24(3):296-7.


An audit of emergency abdominal aortic aneurysm repair to establish the necessity for an emergency vascular surgical rota.

Lobo DN, Riddick AC, Iftikhar SY, Nash JR, Callum KG, Gudgeon AM.

Ann R Coll Surg Engl. 1999 May;81(3):156-60.

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