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Items: 9


A relative quantitative positive/negative ion switching method for untargeted lipidomics via high resolution LC-MS/MS from any biological source.

Breitkopf SB, Ricoult SJH, Yuan M, Xu Y, Peake DA, Manning BD, Asara JM.

Metabolomics. 2017 Mar;13(3). pii: 30. doi: 10.1007/s11306-016-1157-8. Epub 2017 Feb 7.


Sterol Regulatory Element Binding Protein Regulates the Expression and Metabolic Functions of Wild-Type and Oncogenic IDH1.

Ricoult SJ, Dibble CC, Asara JM, Manning BD.

Mol Cell Biol. 2016 Aug 26;36(18):2384-95. doi: 10.1128/MCB.00163-16. Print 2016 Sep 15.


mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.

Ben-Sahra I, Hoxhaj G, Ricoult SJH, Asara JM, Manning BD.

Science. 2016 Feb 12;351(6274):728-733. doi: 10.1126/science.aad0489.


Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP.

Ricoult SJ, Yecies JL, Ben-Sahra I, Manning BD.

Oncogene. 2016 Mar 10;35(10):1250-60. doi: 10.1038/onc.2015.179. Epub 2015 Jun 1.


Tuberous sclerosis complex 2 loss increases lysophosphatidylcholine synthesis in lymphangioleiomyomatosis.

Priolo C, Ricoult SJ, Khabibullin D, Filippakis H, Yu J, Manning BD, Clish C, Henske EP.

Am J Respir Cell Mol Biol. 2015 Jul;53(1):33-41. doi: 10.1165/rcmb.2014-0379RC.


Coordinated regulation of protein synthesis and degradation by mTORC1.

Zhang Y, Nicholatos J, Dreier JR, Ricoult SJ, Widenmaier SB, Hotamisligil GS, Kwiatkowski DJ, Manning BD.

Nature. 2014 Sep 18;513(7518):440-3. doi: 10.1038/nature13492. Epub 2014 Jul 13.


A growing role for mTOR in promoting anabolic metabolism.

Howell JJ, Ricoult SJ, Ben-Sahra I, Manning BD.

Biochem Soc Trans. 2013 Aug;41(4):906-12. doi: 10.1042/BST20130041. Review.


The multifaceted role of mTORC1 in the control of lipid metabolism.

Ricoult SJ, Manning BD.

EMBO Rep. 2013 Mar 1;14(3):242-51. doi: 10.1038/embor.2013.5. Epub 2012 Feb 12. Review.


SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production.

Bell EL, Emerling BM, Ricoult SJ, Guarente L.

Oncogene. 2011 Jun 30;30(26):2986-96. doi: 10.1038/onc.2011.37. Epub 2011 Feb 28.

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