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Items: 1 to 50 of 106

1.

Cultural Identity Confusion and Psychopathology: A Mixed-Methods Study Among Refugees and Asylum Seekers in the Netherlands.

Groen SPN, Richters AJM, Laban CJ, van Busschbach JT, Devillé WLJM.

J Nerv Ment Dis. 2019 Mar;207(3):162-170. doi: 10.1097/NMD.0000000000000935.

2.
3.

An Array-Based Ligand Discovery Platform for Proteins With Short Half-Lives.

Leifer BS, Doyle SK, Richters A, Evans HL, Koehler AN.

Methods Enzymol. 2018;610:191-218. doi: 10.1016/bs.mie.2018.09.019. Epub 2018 Oct 19.

PMID:
30390799
4.

Longitudinal multiple case study on effectiveness of network-based dementia care towards more integration, quality of care, and collaboration in primary care.

Richters A, Nieuwboer MS, Olde Rikkert MGM, Melis RJF, Perry M, van der Marck MA.

PLoS One. 2018 Jun 27;13(6):e0198811. doi: 10.1371/journal.pone.0198811. eCollection 2018.

5.

Response to Vos et al: Modifiable Risk Factors for Prevention of Dementia in Midlife, Late Life and the Oldest-Old: Validation of the LIBRA Index.

Richters A, Claassen AH.

J Alzheimers Dis. 2018 Mar 16. doi: 10.3233/JAD-179008. [Epub ahead of print] No abstract available.

PMID:
29562510
6.

Targeting protein arginine methyltransferase 5 in disease.

Richters A.

Future Med Chem. 2017 Nov;9(17):2081-2098. doi: 10.4155/fmc-2017-0089. Epub 2017 Oct 27. Review.

PMID:
29076773
7.

Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.

Brägelmann J, Dammert MA, Dietlein F, Heuckmann JM, Choidas A, Böhm S, Richters A, Basu D, Tischler V, Lorenz C, Habenberger P, Fang Z, Ortiz-Cuaran S, Leenders F, Eickhoff J, Koch U, Getlik M, Termathe M, Sallouh M, Greff Z, Varga Z, Balke-Want H, French CA, Peifer M, Reinhardt HC, Örfi L, Kéri G, Ansén S, Heukamp LC, Büttner R, Rauh D, Klebl BM, Thomas RK, Sos ML.

Cell Rep. 2017 Sep 19;20(12):2833-2845. doi: 10.1016/j.celrep.2017.08.082.

8.

Quasi-experimental study designs: making a case for non-experimental designs in the spectrum.

Richters A, Melis RJF.

J Clin Epidemiol. 2017 Nov;91:146. doi: 10.1016/j.jclinepi.2017.07.012. Epub 2017 Aug 9. No abstract available.

PMID:
28802673
9.

Evaluation of DementiaNet, a network-based primary care innovation for community-dwelling patients with dementia: protocol for a longitudinal mixed methods multiple case study.

Richters A, Nieuwboer MS, Perry M, Olde Rikkert MGM, Melis RJF, van der Marck MA.

BMJ Open. 2017 Aug 4;7(8):e016433. doi: 10.1136/bmjopen-2017-016433.

10.

Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors.

Plenker D, Riedel M, Brägelmann J, Dammert MA, Chauhan R, Knowles PP, Lorenz C, Keul M, Bührmann M, Pagel O, Tischler V, Scheel AH, Schütte D, Song Y, Stark J, Mrugalla F, Alber Y, Richters A, Engel J, Leenders F, Heuckmann JM, Wolf J, Diebold J, Pall G, Peifer M, Aerts M, Gevaert K, Zahedi RP, Buettner R, Shokat KM, McDonald NQ, Kast SM, Gautschi O, Thomas RK, Sos ML.

Sci Transl Med. 2017 Jun 14;9(394). pii: eaah6144. doi: 10.1126/scitranslmed.aah6144.

11.

Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34.

Robke L, Laraia L, Carnero Corrales MA, Konstantinidis G, Muroi M, Richters A, Winzker M, Engbring T, Tomassi S, Watanabe N, Osada H, Rauh D, Waldmann H, Wu YW, Engel J.

Angew Chem Int Ed Engl. 2017 Jul 3;56(28):8153-8157. doi: 10.1002/anie.201703738. Epub 2017 Jun 12.

PMID:
28544137
12.

Perseverance time of informal caregivers for people with dementia: construct validity, responsiveness and predictive validity.

Richters A, Melis RJ, van Exel NJ, Olde Rikkert MG, van der Marck MA.

Alzheimers Res Ther. 2017 Apr 4;9(1):26. doi: 10.1186/s13195-017-0251-0.

13.

Epigenetic Modulation Using Small Molecules - Targeting Histone Acetyltransferases in Disease.

Richters A, Koehler AN.

Curr Med Chem. 2017;24(37):4121-4150. doi: 10.2174/0929867324666170223153115.

PMID:
28240169
14.

Triple aim improvement for individuals, services and society in dementia care : The DementiaNet collaborative care approach.

Nieuwboer MS, Richters A, van der Marck MA.

Z Gerontol Geriatr. 2017 May;50(Suppl 2):78-83. doi: 10.1007/s00391-017-1196-4. Epub 2017 Feb 20.

15.

Implementation of the Cultural Formulation through a newly developed Brief Cultural Interview: Pilot data from the Netherlands.

Groen SP, Richters A, Laban CJ, Devillé WL.

Transcult Psychiatry. 2017 Feb;54(1):3-22. doi: 10.1177/1363461516678342. Epub 2016 Dec 15.

PMID:
28157446
16.

Cultural Identity Among Afghan and Iraqi Traumatized Refugees: Towards a Conceptual Framework for Mental Health Care Professionals.

Groen SPN, Richters A, Laban CJ, Devillé WLJM.

Cult Med Psychiatry. 2018 Mar;42(1):69-91. doi: 10.1007/s11013-016-9514-7.

17.

A cascade screening approach for the identification of Bcr-Abl myristate pocket binders active against wild type and T315I mutant.

Radi M, Schneider R, Fallacara AL, Botta L, Crespan E, Tintori C, Maga G, Kissova M, Calgani A, Richters A, Musumeci F, Rauh D, Schenone S.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3436-40. doi: 10.1016/j.bmcl.2016.06.051. Epub 2016 Jun 18.

PMID:
27374241
18.

The International Dementia Alliance Instrument for Feasible and Valid Staging of Individuals with Dementia by Informal Caregivers.

Richters A, Melis RJ, Olde Rikkert MG, van der Marck MA.

J Am Geriatr Soc. 2016 Aug;64(8):1674-8. doi: 10.1111/jgs.14205. Epub 2016 Jun 15.

PMID:
27304200
19.

Perseverance Time of Informal Caregivers for Institutionalized Elderly: Construct Validity and Test-Retest Reliability of a Single-Question Instrument.

Richters A, Olde Rikkert MG, van Exel NJ, Melis RJ, van der Marck MA.

J Am Med Dir Assoc. 2016 Aug 1;17(8):761-2. doi: 10.1016/j.jamda.2016.05.001. Epub 2016 Jun 11. No abstract available.

PMID:
27301591
20.

The "treatment gap" in global mental health reconsidered: sociotherapy for collective trauma in Rwanda.

Jansen S, White R, Hogwood J, Jansen A, Gishoma D, Mukamana D, Richters A.

Eur J Psychotraumatol. 2015 Nov 19;6:28706. doi: 10.3402/ejpt.v6.28706. eCollection 2015.

21.

Presence and Number of Positive Surgical Margins after Radical Prostatectomy for Prostate Cancer: Effect on Oncological Outcome in a Population-Based Cohort.

Richters A, Derks J, Fossion LM, Kil PJ, Verhoeven RH, Aarts MJ.

Urol Int. 2015;95(4):472-7. doi: 10.1159/000441012. Epub 2015 Nov 3.

PMID:
26523366
22.

Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach.

Engel J, Richters A, Getlik M, Tomassi S, Keul M, Termathe M, Lategahn J, Becker C, Mayer-Wrangowski S, Grütter C, Uhlenbrock N, Krüll J, Schaumann N, Eppmann S, Kibies P, Hoffgaard F, Heil J, Menninger S, Ortiz-Cuaran S, Heuckmann JM, Tinnefeld V, Zahedi RP, Sos ML, Schultz-Fademrecht C, Thomas RK, Kast SM, Rauh D.

J Med Chem. 2015 Sep 10;58(17):6844-63. doi: 10.1021/acs.jmedchem.5b01082. Epub 2015 Aug 31.

PMID:
26275028
23.

A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.

Dietlein F, Kalb B, Jokic M, Noll EM, Strong A, Tharun L, Ozretić L, Künstlinger H, Kambartel K, Randerath WJ, Jüngst C, Schmitt A, Torgovnick A, Richters A, Rauh D, Siedek F, Persigehl T, Mauch C, Bartkova J, Bradley A, Sprick MR, Trumpp A, Rad R, Saur D, Bartek J, Wolf J, Büttner R, Thomas RK, Reinhardt HC.

Cell. 2015 Jul 2;162(1):146-59. doi: 10.1016/j.cell.2015.05.053. Erratum in: Cell. 2015 Aug 27;162(5):1169.

24.

Covalent-Allosteric Kinase Inhibitors.

Weisner J, Gontla R, van der Westhuizen L, Oeck S, Ketzer J, Janning P, Richters A, Mühlenberg T, Fang Z, Taher A, Jendrossek V, Pelly SC, Bauer S, van Otterlo WA, Rauh D.

Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10313-6. doi: 10.1002/anie.201502142. Epub 2015 Jun 25.

PMID:
26110718
25.

Structure-based design and synthesis of covalent-reversible inhibitors to overcome drug resistance in EGFR.

Basu D, Richters A, Rauh D.

Bioorg Med Chem. 2015 Jun 15;23(12):2767-80. doi: 10.1016/j.bmc.2015.04.038. Epub 2015 Apr 23. Erratum in: Bioorg Med Chem. 2015 Aug 1;23(15):5075.

PMID:
25975640
26.

Neuritogenic militarinone-inspired 4-hydroxypyridones target the stress pathway kinase MAP4K4.

Schröder P, Förster T, Kleine S, Becker C, Richters A, Ziegler S, Rauh D, Kumar K, Waldmann H.

Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12398-403. doi: 10.1002/anie.201501515. Epub 2015 Apr 23.

PMID:
25908259
27.

Identification and further development of potent TBK1 inhibitors.

Richters A, Basu D, Engel J, Ercanoglu MS, Balke-Want H, Tesch R, Thomas RK, Rauh D.

ACS Chem Biol. 2015 Jan 16;10(1):289-98. doi: 10.1021/cb500908d.

PMID:
25540906
28.

Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma.

Tintori C, Fallacara AL, Radi M, Zamperini C, Dreassi E, Crespan E, Maga G, Schenone S, Musumeci F, Brullo C, Richters A, Gasparrini F, Angelucci A, Festuccia C, Delle Monache S, Rauh D, Botta M.

J Med Chem. 2015 Jan 8;58(1):347-61. doi: 10.1021/jm5013159. Epub 2014 Dec 3.

PMID:
25469771
29.

Effect of surgical margin status after radical prostatectomy on health-related quality of life and illness perception in patients with prostate cancer.

Richters A, Derks J, Husson O, Van Onna IEW, Fossion LMCL, Kil PJM, Verhoeven RHA, Aarts MJ.

Urol Oncol. 2015 Jan;33(1):16.e9-16.e15. doi: 10.1016/j.urolonc.2014.10.006. Epub 2014 Nov 14.

PMID:
25456999
30.

Of death and rebirth: life histories of Rwandan female genocide survivors. Conclusion.

Richters A.

Torture. 2014;24 Suppl 1:54-7. No abstract available.

PMID:
24986587
31.

Of death and rebirth: life histories of Rwandan female genocide survivors. Introduction.

Richters A.

Torture. 2014;24 Suppl 1:6-11. No abstract available.

PMID:
24986576
32.

Everyday suffering outside prison walls: a legacy of community justice in post-genocide Rwanda.

Rutayisire T, Richters A.

Soc Sci Med. 2014 Nov;120:413-20. doi: 10.1016/j.socscimed.2014.06.009. Epub 2014 Jun 10.

PMID:
24954521
33.

Identification of type II and III DDR2 inhibitors.

Richters A, Nguyen HD, Phan T, Simard JR, Grütter C, Engel J, Rauh D.

J Med Chem. 2014 May 22;57(10):4252-62. doi: 10.1021/jm500167q. Epub 2014 May 5.

PMID:
24754677
34.

Cell-autonomous and non-cell-autonomous mechanisms of transformation by amplified FGFR1 in lung cancer.

Malchers F, Dietlein F, Schöttle J, Lu X, Nogova L, Albus K, Fernandez-Cuesta L, Heuckmann JM, Gautschi O, Diebold J, Plenker D, Gardizi M, Scheffler M, Bos M, Seidel D, Leenders F, Richters A, Peifer M, Florin A, Mainkar PS, Karre N, Chandrasekhar S, George J, Silling S, Rauh D, Zander T, Ullrich RT, Reinhardt HC, Ringeisen F, Büttner R, Heukamp LC, Wolf J, Thomas RK.

Cancer Discov. 2014 Feb;4(2):246-57. doi: 10.1158/2159-8290.CD-13-0323. Epub 2013 Dec 3.

35.

Incidence of and risk factors for persistent gram-positive bacteraemia and catheter-related thrombosis in haematopoietic stem cell transplantation.

Richters A, van Vliet M, Peer PG, Verweij PE, Laros-van Gorkom BA, Blijlevens NM, Donnelly JP, van der Velden WJ.

Bone Marrow Transplant. 2014 Feb;49(2):264-9. doi: 10.1038/bmt.2013.172. Epub 2013 Nov 4.

PMID:
24185587
36.

Metabolically stable dibenzo[b,e]oxepin-11(6H)-ones as highly selective p38 MAP kinase inhibitors: optimizing anti-cytokine activity in human whole blood.

Baur B, Storch K, Martz KE, Goettert MI, Richters A, Rauh D, Laufer SA.

J Med Chem. 2013 Nov 14;56(21):8561-78. doi: 10.1021/jm401276h. Epub 2013 Nov 5.

PMID:
24131218
37.

Targeting gain of function and resistance mutations in Abl and KIT by hybrid compound design.

Richters A, Ketzer J, Getlik M, Grütter C, Schneider R, Heuckmann JM, Heynck S, Sos ML, Gupta A, Unger A, Schultz-Fademrecht C, Thomas RK, Bauer S, Rauh D.

J Med Chem. 2013 Jul 25;56(14):5757-72. doi: 10.1021/jm4004076. Epub 2013 Jul 10.

PMID:
23773153
38.

Sexual transgression and social disconnection: healing through community-based sociotherapy in Rwanda.

Richters A, Rutayisire T, Slegh H.

Cult Health Sex. 2013;15 Suppl 4:S581-93. doi: 10.1080/13691058.2013.780261. Epub 2013 May 7.

PMID:
23651140
39.

De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragments.

Urich R, Wishart G, Kiczun M, Richters A, Tidten-Luksch N, Rauh D, Sherborne B, Wyatt PG, Brenk R.

ACS Chem Biol. 2013 May 17;8(5):1044-52. doi: 10.1021/cb300729y. Epub 2013 Mar 27.

40.

A framework for identification of actionable cancer genome dependencies in small cell lung cancer.

Sos ML, Dietlein F, Peifer M, Schöttle J, Balke-Want H, Müller C, Koker M, Richters A, Heynck S, Malchers F, Heuckmann JM, Seidel D, Eyers PA, Ullrich RT, Antonchick AP, Vintonyak VV, Schneider PM, Ninomiya T, Waldmann H, Büttner R, Rauh D, Heukamp LC, Thomas RK.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17034-9. doi: 10.1073/pnas.1207310109. Epub 2012 Oct 3.

41.

Targeting GSK3 from Ustilago maydis: type-II kinase inhibitors as potential antifungals.

Grütter C, Simard JR, Mayer-Wrangowski SC, Schreier PH, Pérez-Martín J, Richters A, Getlik M, Gutbrod O, Braun CA, Beck ME, Rauh D.

ACS Chem Biol. 2012 Jul 20;7(7):1257-67. doi: 10.1021/cb300128b. Epub 2012 May 15.

PMID:
22545924
42.

A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase.

Koch A, Rode HB, Richters A, Rauh D, Hauf S.

ACS Chem Biol. 2012 Apr 20;7(4):723-31. doi: 10.1021/cb200465c. Epub 2012 Feb 1.

PMID:
22264160
43.

Suffering of childless women in Bangladesh: the intersection of social identities of gender and class.

Nahar P, Richters A.

Anthropol Med. 2011 Dec;18(3):327-38. doi: 10.1080/13648470.2011.615911.

PMID:
22060126
44.

Severe maternal morbidity among immigrant women in the Netherlands: patients' perspectives.

Jonkers M, Richters A, Zwart J, Öry F, van Roosmalen J.

Reprod Health Matters. 2011 May;19(37):144-53. doi: 10.1016/S0968-8080(11)37556-8.

45.

The epidemiology of spirit possession in the aftermath of mass political violence in Mozambique.

Igreja V, Dias-Lambranca B, Hershey DA, Racin L, Richters A, Reis R.

Soc Sci Med. 2010 Aug;71(3):592-599. doi: 10.1016/j.socscimed.2010.04.024. Epub 2010 May 12.

PMID:
20542612
46.

Ethnic disparity in severe acute maternal morbidity: a nationwide cohort study in the Netherlands.

Zwart JJ, Jonkers MD, Richters A, Ory F, Bloemenkamp KW, Duvekot JJ, van Roosmalen J.

Eur J Public Health. 2011 Apr;21(2):229-34. doi: 10.1093/eurpub/ckq046. Epub 2010 Jun 3.

PMID:
20522516
47.

Silencing distressed children in the context of war in northern Uganda: an analysis of its dynamics and its health consequences.

Akello G, Reis R, Richters A.

Soc Sci Med. 2010 Jul;71(2):213-220. doi: 10.1016/j.socscimed.2010.03.030. Epub 2010 Apr 13.

PMID:
20452108
48.

Proteus in the world of proteins: conformational changes in protein kinases.

Rabiller M, Getlik M, Klüter S, Richters A, Tückmantel S, Simard JR, Rauh D.

Arch Pharm (Weinheim). 2010 Apr;343(4):193-206. doi: 10.1002/ardp.201000028. Review.

PMID:
20336692
49.

Obstetric intensive care unit admission: a 2-year nationwide population-based cohort study.

Zwart JJ, Dupuis JR, Richters A, Ory F, van Roosmalen J.

Intensive Care Med. 2010 Feb;36(2):256-63. doi: 10.1007/s00134-009-1707-x. Epub 2009 Nov 10.

50.

Agricultural cycle and the prevalence of posttraumatic stress disorder: a longitudinal community study in postwar Mozambique.

Igreja V, Kleijn W, Dias-Lambranca B, Hershey DA, Calero C, Richters A.

J Trauma Stress. 2009 Jun;22(3):172-9. doi: 10.1002/jts.20412.

PMID:
19489043

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