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Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout.

Wrigley R, Phipps-Green AJ, Topless RK, Major TJ, Cadzow M, Riches P, Tausche AK, Janssen M, Joosten LAB, Jansen TL, So A, Harré Hindmarsh J, Stamp LK, Dalbeth N, Merriman TR.

Arthritis Res Ther. 2020 Mar 12;22(1):45. doi: 10.1186/s13075-020-2136-z.


Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout.

Klück V, van Deuren RC, Cavalli G, Shaukat A, Arts P, Cleophas MC, Crișan TO, Tausche AK, Riches P, Dalbeth N, Stamp LK, Hindmarsh JH, Jansen TLTA, Janssen M, Steehouwer M, Lelieveld S, van de Vorst M, Gilissen C, Dagna L, Van de Veerdonk FL, Eisenmesser EZ, Kim S, Merriman TR, Hoischen A, Netea MG, Dinarello CA, Joosten LA.

Ann Rheum Dis. 2020 Apr;79(4):536-544. doi: 10.1136/annrheumdis-2019-216233. Epub 2020 Feb 29.


Systematic genetic analysis of early-onset gout: ABCG2 is the only associated locus.

Zaidi F, Narang RK, Phipps-Green A, Gamble GG, Tausche AK, So A, Riches P, Andres M, Perez-Ruiz F, Doherty M, Janssen M, Joosten LAB, Jansen TL, Kurreeman F, Torres RJ, McCarthy GM, Miner JN, Stamp LK, Merriman TR, Dalbeth N.

Rheumatology (Oxford). 2020 Jan 30. pii: kez685. doi: 10.1093/rheumatology/kez685. [Epub ahead of print]


On the relationships between applied force, photography technique, and the quantification of bruise appearance.

Black HI, Coupaud S, Daéid NN, Riches PE.

Forensic Sci Int. 2019 Dec;305:109998. doi: 10.1016/j.forsciint.2019.109998. Epub 2019 Oct 22.


Computer assisted orthopaedic surgery: Past, present and future.

Picard F, Deakin AH, Riches PE, Deep K, Baines J.

Med Eng Phys. 2019 Oct;72:55-65. doi: 10.1016/j.medengphy.2019.08.005.


3D bioprinting of mature bacterial biofilms for antimicrobial resistance drug testing.

Ning E, Turnbull G, Clarke J, Picard F, Riches P, Vendrell M, Graham D, Wark AW, Faulds K, Shu W.

Biofabrication. 2019 Sep 13;11(4):045018. doi: 10.1088/1758-5090/ab37a0.


Health costs and efficiencies of patient-specific and single-use instrumentation in total knee arthroplasty: a randomised controlled trial.

Attard A, Tawy GF, Simons M, Riches P, Rowe P, Biant LC.

BMJ Open Qual. 2019 May 29;8(2):e000493. doi: 10.1136/bmjoq-2018-000493. eCollection 2019.


Long-Term Effects of Teriparatide Followed by Antiresorptive Therapy on Clinical Outcomes in Patients with Severe Spinal Osteoporosis.

Oswald AJ, Berg K, Ralston SH, Riches PL.

Calcif Tissue Int. 2019 Aug;105(2):148-155. doi: 10.1007/s00223-019-00563-8. Epub 2019 May 21.


Point-of-care uric acid testing is useful in routine clinical care of gout.

Riches PL, Sing K, Berg K.

Arthritis Res Ther. 2019 May 9;21(1):117. doi: 10.1186/s13075-019-1891-1. No abstract available.


The assessment of instability in the osteoarthritic knee.

Wallace DT, Riches PE, Picard F.

EFORT Open Rev. 2019 Mar 8;4(3):70-76. doi: 10.1302/2058-5241.4.170079. eCollection 2019 Mar. Review.


The ionic contribution of proteoglycans to mechanical stiffness of the meniscus.

Mahmood F, Clarke J, Riches P.

Med Eng Phys. 2019 Feb;64:23-27. doi: 10.1016/j.medengphy.2018.12.010. Epub 2018 Dec 27.


Lower limb alignment becomes more varus and hyperextended from supine to bipedal stance in asymptomatic, osteoarthritic and prosthetic neutral or varus knees.

Brown MJC, Deakin AH, Picard F, Riches PE, Clarke JV.

Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1635-1641. doi: 10.1007/s00167-018-5273-z. Epub 2018 Nov 10.


Inertial properties of the German Shepherd Dog.

Jones OY, Raschke SU, Riches PE.

PLoS One. 2018 Oct 19;13(10):e0206037. doi: 10.1371/journal.pone.0206037. eCollection 2018.


3D bioactive composite scaffolds for bone tissue engineering.

Turnbull G, Clarke J, Picard F, Riches P, Jia L, Han F, Li B, Shu W.

Bioact Mater. 2017 Dec 1;3(3):278-314. doi: 10.1016/j.bioactmat.2017.10.001. eCollection 2018 Sep. Review.


Development and mechanical characterisation of self-compressed collagen gels.

Andriakopoulou CE, Zadpoor AA, Grant MH, Riches PE.

Mater Sci Eng C Mater Biol Appl. 2018 Mar 1;84:243-247. doi: 10.1016/j.msec.2017.11.043. Epub 2017 Nov 28.


Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density.

Alonso N, Estrada K, Albagha OME, Herrera L, Reppe S, Olstad OK, Gautvik KM, Ryan NM, Evans KL, Nielson CM, Hsu YH, Kiel DP, Markozannes G, Ntzani EE, Evangelou E, Feenstra B, Liu X, Melbye M, Masi L, Brandi ML, Riches P, Daroszewska A, Olmos JM, Valero C, Castillo J, Riancho JA, Husted LB, Langdahl BL, Brown MA, Duncan EL, Kaptoge S, Khaw KT, Usategui-Martín R, Del Pino-Montes J, González-Sarmiento R, Lewis JR, Prince RL, D'Amelio P, García-Giralt N, Nogués X, Mencej-Bedrac S, Marc J, Wolstein O, Eisman JA, Oei L, Medina-Gómez C, Schraut KE, Navarro P, Wilson JF, Davies G, Starr J, Deary I, Tanaka T, Ferrucci L, Gianfrancesco F, Gennari L, Lucas G, Elosua R, Uitterlinden AG, Rivadeneira F, Ralston SH.

Ann Rheum Dis. 2018 Mar;77(3):378-385. doi: 10.1136/annrheumdis-2017-212469. Epub 2017 Nov 23.


Identification of Movement Strategies During the Sit-to-Walk Movement in Patients With Knee Osteoarthritis.

Komaris DS, Govind C, Murphy A, Ewen A, Riches P.

J Appl Biomech. 2018 Apr 1;34(2):96-103. doi: 10.1123/jab.2016-0279. Epub 2018 Apr 6.


Lower limb alignment and laxity measures before, during and after total knee arthroplasty: A prospective cohort study.

Clarke JV, Deakin AH, Picard F, Riches PE.

Clin Biomech (Bristol, Avon). 2017 Aug;47:61-65. doi: 10.1016/j.clinbiomech.2017.05.013. Epub 2017 May 26.


Assessment of knee alignment with varus and valgus force through the range of flexion with non-invasive navigation.

Henderson F, Alho R, Riches P, Picard F.

J Med Eng Technol. 2017 Aug;41(6):444-459. doi: 10.1080/03091902.2017.1333164. Epub 2017 Jun 6.


A numerical investigation and experimental verification of size effects in loaded bovine cortical bone.

Frame JC, Wheel MA, Riches PE.

Int J Numer Method Biomed Eng. 2018 Jan;34(1). doi: 10.1002/cnm.2903. Epub 2017 Jul 19.


Autoantibodies to Osteoprotegerin are Associated with Low Hip Bone Mineral Density and History of Fractures in Axial Spondyloarthritis: A Cross-Sectional Observational Study.

Hauser B, Zhao S, Visconti MR, Riches PL, Fraser WD, Piec I, Goodson NJ, Ralston SH.

Calcif Tissue Int. 2017 Oct;101(4):375-383. doi: 10.1007/s00223-017-0291-2. Epub 2017 May 22.


Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout.

Rasheed H, Phipps-Green AJ, Topless R, Smith MD, Hill C, Lester S, Rischmueller M, Janssen M, Jansen TL, Joosten LA, Radstake TR, Riches PL, Tausche AK, Lioté F, So A, van Rij A, Jones GT, McCormick SP, Harrison AA, Stamp LK, Dalbeth N, Merriman TR.

Rheumatology (Oxford). 2016 Aug;55(8):1421-30. doi: 10.1093/rheumatology/kew057. Epub 2016 Apr 18.


Patient rated outcomes study into the surgical interventions available for the rheumatoid hand and wrist.

Riches PL, Elherik FK, Dolan S, Unglaub F, Breusch SJ.

Arch Orthop Trauma Surg. 2016 Apr;136(4):563-70. doi: 10.1007/s00402-016-2412-1. Epub 2016 Feb 10.


The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets.

Rasheed H, McKinney C, Stamp LK, Dalbeth N, Topless RK, Day R, Kannangara D, Williams K, Smith M, Janssen M, Jansen TL, Joosten LA, Radstake TR, Riches PL, Tausche AK, Lioté F, Lu L, Stahl EA, Choi HK, So A, Merriman TR.

PLoS One. 2016 Jan 25;11(1):e0147939. doi: 10.1371/journal.pone.0147939. eCollection 2016.


Thermal Damage Done to Bone by Burring and Sawing With and Without Irrigation in Knee Arthroplasty.

Tawy GF, Rowe PJ, Riches PE.

J Arthroplasty. 2016 May;31(5):1102-8. doi: 10.1016/j.arth.2015.11.002. Epub 2015 Nov 10.


Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout.

McKinney C, Stamp LK, Dalbeth N, Topless RK, Day RO, Kannangara DR, Williams KM, Janssen M, Jansen TL, Joosten LA, Radstake TR, Riches PL, Tausche AK, Lioté F, So A, Merriman TR.

Arthritis Res Ther. 2015 Oct 13;17:288. doi: 10.1186/s13075-015-0802-3.


The mechanical effects of extracorporeal irradiation on bone.

Gupta S, Cafferky D, Cowie F, Riches P, Mahendra A.

Bone Joint J. 2015 Aug;97-B(8):1152-6. doi: 10.1302/0301-620X.97B8.35729.


Characterisation of osteoprotegerin autoantibodies in coeliac disease.

Real A, Gilbert N, Hauser B, Kennedy N, Shand A, Gillett H, Gillett P, Goddard C, Cebolla Á, Sousa C, Fraser WD, Satsangi J, Ralston SH, Riches PL.

Calcif Tissue Int. 2015 Aug;97(2):125-33. doi: 10.1007/s00223-015-0023-4. Epub 2015 Jun 20.


Tensile properties of the transverse carpal ligament and carpal tunnel complex.

Ugbolue UC, Gislason MK, Carter M, Fogg QA, Riches PE, Rowe PJ.

Clin Biomech (Bristol, Avon). 2015 Aug;30(7):649-56. doi: 10.1016/j.clinbiomech.2015.05.010. Epub 2015 May 24.


Autoantibodies to osteoprotegerin are associated with increased bone resorption in rheumatoid arthritis.

Hauser B, Riches PL, Gilchrist T, Visconti MR, Wilson JF, Ralston SH.

Ann Rheum Dis. 2015 Aug;74(8):1631-2. doi: 10.1136/annrheumdis-2014-207219. Epub 2015 Apr 29. No abstract available.


High degree of accuracy of a novel image-free handheld robot for unicondylar knee arthroplasty in a cadaveric study.

Lonner JH, Smith JR, Picard F, Hamlin B, Rowe PJ, Riches PE.

Clin Orthop Relat Res. 2015 Jan;473(1):206-12. doi: 10.1007/s11999-014-3764-x.


Validity and reliability of an alternative method for measuring power output during six-second all-out cycling.

Watson M, Bibbo D, Duffy CR, Riches PE, Conforto S, Macaluso A.

J Appl Biomech. 2014 Aug;30(4):598-603. doi: 10.1123/jab.2013-0317. Epub 2014 Jun 30.


Functional and patient-reported outcome of partial wrist denervation versus the Mannerfelt wrist arthrodesis in the rheumatoid wrist.

Riches PL, Elherik FK, Breusch SJ.

Arch Orthop Trauma Surg. 2014 Jul;134(7):1037-44. doi: 10.1007/s00402-014-2018-4. Epub 2014 Jun 7.


Prevalence and clinical prediction of osteoporosis in a contemporary cohort of patients with rheumatoid arthritis.

Hauser B, Riches PL, Wilson JF, Horne AE, Ralston SH.

Rheumatology (Oxford). 2014 Oct;53(10):1759-66. doi: 10.1093/rheumatology/keu162. Epub 2014 Apr 24.


On the poisson's ratio of the nucleus pulposus.

Farrell MD, Riches PE.

J Biomech Eng. 2013 Oct;135(10):104501. doi: 10.1115/1.4025180.


Up-titration of allopurinol in patients with gout.

Jennings CG, Mackenzie IS, Flynn R, Ford I, Nuki G, De Caterina R, Riches PL, Ralston SH, MacDonald TM; FAST study group.

Semin Arthritis Rheum. 2014 Aug;44(1):25-30. doi: 10.1016/j.semarthrit.2014.01.004. Epub 2014 Jan 23.


Research synthesis of recommended acetabular cup orientations for total hip arthroplasty.

Harrison CL, Thomson AI, Cutts S, Rowe PJ, Riches PE.

J Arthroplasty. 2014 Feb;29(2):377-82. doi: 10.1016/j.arth.2013.06.026. Epub 2013 Aug 17.


Accuracy of a freehand sculpting tool for unicondylar knee replacement.

Smith JR, Riches PE, Rowe PJ.

Int J Med Robot. 2014 Jun;10(2):162-9. doi: 10.1002/rcs.1522. Epub 2013 Aug 11.


On the Poisson’s ratio of the nucleus pulposus.

Farrell MD, Riches PE.

J Biomech Eng. 2013 Oct 1;135(10):104501-4.


Confined compression of collagen hydrogels.

Busby GA, Grant MH, Mackay SP, Riches PE.

J Biomech. 2013 Feb 22;46(4):837-40. doi: 10.1016/j.jbiomech.2012.11.048. Epub 2012 Dec 23.


Standardising the clinical assessment of coronal knee laxity.

Clarke JV, Wilson WT, Wearing SC, Picard F, Riches PE, Deakin AH.

Proc Inst Mech Eng H. 2012 Sep;226(9):699-708.


Comparison of power and EMG during 6-s all-out cycling between young and older women.

Duffy CR, Stewart D, Pecoraro F, Riches PE, Farina D, Macaluso A.

J Sports Sci. 2012;30(12):1311-21. doi: 10.1080/02640414.2012.710752. Epub 2012 Aug 1.


Controlling the variable of pressure in the production of test footwear impressions.

Farrugia KJ, Riches P, Bandey H, Savage K, NicDaéid N.

Sci Justice. 2012 Sep;52(3):168-76. doi: 10.1016/j.scijus.2011.11.002. Epub 2011 Dec 22.


The effects of upper limb loading on spinal shrinkage during treadmill walking.

Watson H, Simpson A, Riches PE.

Eur Spine J. 2012 Dec;21(12):2688-92. doi: 10.1007/s00586-012-2377-x. Epub 2012 May 29.


Biomechanical analysis of locked and non-locked plate fixation of the clavicle.

Little KJ, Riches PE, Fazzi UG.

Injury. 2012 Jun;43(6):921-5. doi: 10.1016/j.injury.2012.02.007. Epub 2012 Mar 8.


Non-invasive computer-assisted measurement of knee alignment.

Clarke JV, Riches PE, Picard F, Deakin AH.

Comput Aided Surg. 2012;17(1):29-39. doi: 10.3109/10929088.2011.635217. Epub 2011 Nov 30.


Recent insights into the biology of bone turnover.

Riches PL, Ralston SH.

J R Coll Physicians Edinb. 2010 Mar;40(1):66-9. doi: 10.4997/JRCPE.2010.113. Review. No abstract available.


Genetic variation in the TNFRSF11A gene encoding RANK is associated with susceptibility to Paget's disease of bone.

Chung PY, Beyens G, Riches PL, Van Wesenbeeck L, de Freitas F, Jennes K, Daroszewska A, Fransen E, Boonen S, Geusens P, Vanhoenacker F, Verbruggen L, Van Offel J, Goemaere S, Zmierczak HG, Westhovens R, Karperien M, Papapoulos S, Ralston SH, Devogelaer JP, Van Hul W.

J Bone Miner Res. 2010 Dec;25(12):2592-605. doi: 10.1002/jbmr.162. Epub 2010 Jun 18. Erratum in: J Bone Miner Res. 2011 Feb;26(2):439.


Osteoporosis associated with neutralizing autoantibodies against osteoprotegerin.

Riches PL, McRorie E, Fraser WD, Determann C, van't Hof R, Ralston SH.

N Engl J Med. 2009 Oct 8;361(15):1459-65. doi: 10.1056/NEJMoa0810925.

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