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Items: 1 to 50 of 169


Gene-environment interactions in Alzheimer's Disease: A potential path to precision medicine.

Eid A, Mhatre I, Richardson JR.

Pharmacol Ther. 2019 Mar 12. pii: S0163-7258(19)30044-0. doi: 10.1016/j.pharmthera.2019.03.005. [Epub ahead of print]


Hepatic carboxylesterases are differentially regulated in PPARα-null mice treated with perfluorooctanoic acid.

Wen X, Baker AA, Klaassen CD, Corton JC, Richardson JR, Aleksunes LM.

Toxicology. 2019 Mar 15;416:15-22. doi: 10.1016/j.tox.2019.01.014. Epub 2019 Jan 24.


Corrigendum to "Regional Susceptibility to ER Stress and Protection by Salubrinal Following a Single Exposure to Deltamethrin".

Hossain MM, Sivaram G, Richardson JR.

Toxicol Sci. 2019 Mar 1;168(1):281. doi: 10.1093/toxsci/kfy305. No abstract available.


Staphylococcus aureus PSM Peptides Modulate Human Monocyte-Derived Dendritic Cells to Prime Regulatory T Cells.

Richardson JR, Armbruster NS, Günter M, Henes J, Autenrieth SE.

Front Immunol. 2018 Nov 13;9:2603. doi: 10.3389/fimmu.2018.02603. eCollection 2018.


Time to get Personal: A Framework for Personalized Targeting of Oxidative Stress in Neurotoxicity and Neurodegenerative Disease.

Neal M, Richardson JR.

Curr Opin Toxicol. 2018 Feb;7:127-132. doi: 10.1016/j.cotox.2018.02.003. Epub 2018 Feb 15.


Regional Susceptibility to ER Stress and Protection by Salubrinal Following a Single Exposure to Deltamethrin.

Hossain MM, Sivaram G, Richardson JR.

Toxicol Sci. 2019 Jan 1;167(1):249-257. doi: 10.1093/toxsci/kfy238.


Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.

Szilagyi JT, Fussell KC, Wang Y, Jan YH, Mishin V, Richardson JR, Heck DE, Yang S, Aleksunes LM, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2018 Nov 15;359:102-107. doi: 10.1016/j.taap.2018.09.011. Epub 2018 Sep 15.


Knockdown of Butyrylcholinesterase but Not Inhibition by Chlorpyrifos Alters Early Differentiation Mechanisms in Human Neural Stem Cells.

Tiethof AK, Richardson JR, Hart RP.

Toxics. 2018 Sep 1;6(3). pii: E52. doi: 10.3390/toxics6030052.


The anti-parkinsonian drug zonisamide reduces neuroinflammation: Role of microglial Nav 1.6.

Hossain MM, Weig B, Reuhl K, Gearing M, Wu LJ, Richardson JR.

Exp Neurol. 2018 Oct;308:111-119. doi: 10.1016/j.expneurol.2018.07.005. Epub 2018 Jul 12.


RNAseq analysis of hippocampal microglia after kainic acid-induced seizures.

Bosco DB, Zheng J, Xu Z, Peng J, Eyo UB, Tang K, Yan C, Huang J, Feng L, Wu G, Richardson JR, Wang H, Wu LJ.

Mol Brain. 2018 Jun 20;11(1):34. doi: 10.1186/s13041-018-0376-5.


Evidence of Oropharyngeal Dysfunction in Feeding in the Rat Rotenone Model of Parkinson's Disease.

Gould FDH, Gross A, German RZ, Richardson JR.

Parkinsons Dis. 2018 Mar 11;2018:6537072. doi: 10.1155/2018/6537072. eCollection 2018.


The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor.

Neal ML, Boyle AM, Budge KM, Safadi FF, Richardson JR.

J Neuroinflammation. 2018 Mar 8;15(1):73. doi: 10.1186/s12974-018-1100-1.


Epigenetic regulation of astrocyte function in neuroinflammation and neurodegeneration.

Neal M, Richardson JR.

Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):432-443. doi: 10.1016/j.bbadis.2017.11.004. Epub 2017 Nov 4. Review.


MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson's Disease Phenotype.

Geldenhuys WJ, Benkovic SA, Lin L, Yonutas HM, Crish SD, Sullivan PG, Darvesh AS, Brown CM, Richardson JR.

ACS Chem Neurosci. 2017 Dec 20;8(12):2759-2765. doi: 10.1021/acschemneuro.7b00287. Epub 2017 Sep 27.


Glycoprotein NMB: an Emerging Role in Neurodegenerative Disease.

Budge KM, Neal ML, Richardson JR, Safadi FF.

Mol Neurobiol. 2018 Jun;55(6):5167-5176. doi: 10.1007/s12035-017-0707-z. Epub 2017 Aug 30. Review.


Corrigendum to "Ephrin-A5 regulates inter-male aggression in mice" [Behav. Brain Res. 286 (June) (2015) 300-307].

Sheleg M, Yochum CL, Richardson JR, Wagner GC, Zhou R.

Behav Brain Res. 2017 Sep 29;335:223. doi: 10.1016/j.bbr.2017.08.019. Epub 2017 Aug 18. No abstract available.


Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide.

Beier EE, Neal M, Alam G, Edler M, Wu LJ, Richardson JR.

Neurobiol Dis. 2017 Dec;108:115-127. doi: 10.1016/j.nbd.2017.08.009. Epub 2017 Aug 18.


Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1.

Green AL, Zhan L, Eid A, Zarbl H, Guo GL, Richardson JR.

Neuropharmacology. 2017 Oct;125:189-196. doi: 10.1016/j.neuropharm.2017.07.020. Epub 2017 Jul 22.


The effect of fibroblast growth factor 15 deficiency on the development of high fat diet induced non-alcoholic steatohepatitis.

Schumacher JD, Kong B, Pan Y, Zhan L, Sun R, Aa J, Rizzolo D, Richardson JR, Chen A, Goedken M, Aleksunes LM, Laskin DL, Guo GL.

Toxicol Appl Pharmacol. 2017 Sep 1;330:1-8. doi: 10.1016/j.taap.2017.06.023. Epub 2017 Jul 1.


Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.

Alam G, Edler M, Burchfield S, Richardson JR.

Neurotoxicology. 2017 May;60:99-106. doi: 10.1016/j.neuro.2017.03.008. Epub 2017 Apr 1.


Dissociation of morphine analgesic effects in the sensory and affective components of formalin-induced spontaneous pain in male and female rats.

Harton LR, Richardson JR, Armendariz A, Nazarian A.

Brain Res. 2017 Mar 1;1658:36-41. doi: 10.1016/j.brainres.2017.01.011. Epub 2017 Jan 12.


Variables associated with administration of analgesia, nurse-initiated analgesia and early analgesia in the emergency department.

Taylor DM, Chen J, Khan M, Lee M, Rajee M, Yeoh M, Richardson JR, Ugoni AM.

Emerg Med J. 2017 Jan;34(1):13-19. doi: 10.1136/emermed-2016-206044. Epub 2016 Oct 27.


Pyrethroid Insecticides Directly Activate Microglia Through Interaction With Voltage-Gated Sodium Channels.

Hossain MM, Liu J, Richardson JR.

Toxicol Sci. 2017 Jan;155(1):112-123. doi: 10.1093/toxsci/kfw187. Epub 2016 Sep 21.


Staphylococcus aureus PSM peptides induce tolerogenic dendritic cells upon treatment with ligands of extracellular and intracellular TLRs.

Armbruster NS, Richardson JR, Schreiner J, Klenk J, Günter M, Autenrieth SE.

Int J Med Microbiol. 2016 Dec;306(8):666-674. doi: 10.1016/j.ijmm.2016.09.002. Epub 2016 Sep 3.


Novel approaches to mitigating parathion toxicity: targeting cytochrome P450-mediated metabolism with menadione.

Jan YH, Richardson JR, Baker AA, Mishin V, Heck DE, Laskin DL, Laskin JD.

Ann N Y Acad Sci. 2016 Aug;1378(1):80-86. doi: 10.1111/nyas.13156. Epub 2016 Jul 21. Review.


The TARGET pain study: Lessons from a painful marathon.

Thom ON, Keijzers G, Taylor DM, Fatovich DM, Finucci DP, Furyk J, Jin SW, Macdonald SP, Mitenko HM, Richardson JR, Ting JY, Gibbs CR, Chalkley DR.

Emerg Med Australas. 2016 Oct;28(5):603-6. doi: 10.1111/1742-6723.12583. Epub 2016 Jun 26.


Developmental pyrethroid exposure causes long-term decreases of neuronal sodium channel expression.

Magby JP, Richardson JR.

Neurotoxicology. 2017 May;60:274-279. doi: 10.1016/j.neuro.2016.04.002. Epub 2016 Apr 4.


Trimethyltin intoxication induces the migration of ventricular/subventricular zone cells to the injured murine hippocampus.

Weig BC, Richardson JR, Lowndes HE, Reuhl KR.

Neurotoxicology. 2016 May;54:72-80. doi: 10.1016/j.neuro.2016.03.023. Epub 2016 Apr 1.


Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium.

Szilagyi JT, Mishin V, Heck DE, Jan YH, Aleksunes LM, Richardson JR, Heindel ND, Laskin DL, Laskin JD.

Toxicol Sci. 2016 May;151(1):150-9. doi: 10.1093/toxsci/kfw031. Epub 2016 Feb 14.


PSM Peptides of Staphylococcus aureus Activate the p38-CREB Pathway in Dendritic Cells, Thereby Modulating Cytokine Production and T Cell Priming.

Armbruster NS, Richardson JR, Schreiner J, Klenk J, Günter M, Kretschmer D, Pöschel S, Schenke-Layland K, Kalbacher H, Clark K, Autenrieth SE.

J Immunol. 2016 Feb 1;196(3):1284-92. doi: 10.4049/jimmunol.1502232. Epub 2016 Jan 4.


Laparoscopic radical 'no-touch' left pancreatosplenectomy for pancreatic ductal adenocarcinoma: technique and results.

Abu Hilal M, Richardson JR, de Rooij T, Dimovska E, Al-Saati H, Besselink MG.

Surg Endosc. 2016 Sep;30(9):3830-8. doi: 10.1007/s00464-015-4685-9. Epub 2015 Dec 16.


Best-practice pain management in the emergency department: A cluster-randomised, controlled, intervention trial.

Taylor DM, Fatovich DM, Finucci DP, Furyk J, Jin SW, Keijzers G, Macdonald SP, Mitenko HM, Richardson JR, Ting JY, Thom ON, Ugoni AM, Hughes JA, Bost N, Ward ML, Gibbs CR, Macdonald E, Chalkley DR.

Emerg Med Australas. 2015 Dec;27(6):549-557. doi: 10.1111/1742-6723.12498. Epub 2015 Nov 24.


Comparative Proteomic Analysis of Carbonylated Proteins from the Striatum and Cortex of Pesticide-Treated Mice.

Coughlan C, Walker DI, Lohr KM, Richardson JR, Saba LM, Caudle WM, Fritz KS, Roede JR.

Parkinsons Dis. 2015;2015:812532. doi: 10.1155/2015/812532. Epub 2015 Aug 9.


Vitamin K3 (menadione) redox cycling inhibits cytochrome P450-mediated metabolism and inhibits parathion intoxication.

Jan YH, Richardson JR, Baker AA, Mishin V, Heck DE, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2015 Oct 1;288(1):114-20. doi: 10.1016/j.taap.2015.07.023. Epub 2015 Jul 23.


Isoform-Specific Regulation of Mouse Carboxylesterase Expression and Activity by Prototypical Transcriptional Activators.

Baker AA, Guo GL, Aleksunes LM, Richardson JR.

J Biochem Mol Toxicol. 2015 Dec;29(12):545-51. doi: 10.1002/jbt.21725. Epub 2015 Jul 15.


Selective damage to dopaminergic transporters following exposure to the brominated flame retardant, HBCDD.

Genskow KR, Bradner JM, Hossain MM, Richardson JR, Caudle WM.

Neurotoxicol Teratol. 2015 Nov-Dec;52(Pt B):162-9. doi: 10.1016/ Epub 2015 Jun 12.


Association of pyrethroid pesticide exposure with attention-deficit/hyperactivity disorder in a nationally representative sample of U.S. children.

Wagner-Schuman M, Richardson JR, Auinger P, Braun JM, Lanphear BP, Epstein JN, Yolton K, Froehlich TE.

Environ Health. 2015 May 28;14:44. doi: 10.1186/s12940-015-0030-y.


Epigenetic Regulation of Dopamine Transporter mRNA Expression in Human Neuroblastoma Cells.

Green AL, Hossain MM, Tee SC, Zarbl H, Guo GL, Richardson JR.

Neurochem Res. 2015 Jul;40(7):1372-8. doi: 10.1007/s11064-015-1601-6. Epub 2015 May 12.


Developmental Deltamethrin Exposure Causes Persistent Changes in Dopaminergic Gene Expression, Neurochemistry, and Locomotor Activity in Zebrafish.

Kung TS, Richardson JR, Cooper KR, White LA.

Toxicol Sci. 2015 Aug;146(2):235-43. doi: 10.1093/toxsci/kfv087. Epub 2015 Apr 24.


With talk of Medicare reform, let's not neglect vertical equity.

Dalziel KM, Richardson JR.

Med J Aust. 2015 Apr 6;202(6):292-3. No abstract available.


Ephrin-A5 regulates inter-male aggression in mice.

Sheleg M, Yochum CL, Richardson JR, Wagner GC, Zhou R.

Behav Brain Res. 2015 Jun 1;286:300-7. doi: 10.1016/j.bbr.2015.03.001. Epub 2015 Mar 6. Erratum in: Behav Brain Res. 2017 Sep 29;335:223.


Modulation of microglial process convergence toward neuronal dendrites by extracellular calcium.

Eyo UB, Gu N, De S, Dong H, Richardson JR, Wu LJ.

J Neurosci. 2015 Feb 11;35(6):2417-22. doi: 10.1523/JNEUROSCI.3279-14.2015.


Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder.

Richardson JR, Taylor MM, Shalat SL, Guillot TS 3rd, Caudle WM, Hossain MM, Mathews TA, Jones SR, Cory-Slechta DA, Miller GW.

FASEB J. 2015 May;29(5):1960-72. doi: 10.1096/fj.14-260901. Epub 2015 Jan 28.


Sulfa drugs inhibit sepiapterin reduction and chemical redox cycling by sepiapterin reductase.

Yang S, Jan YH, Mishin V, Richardson JR, Hossain MM, Heindel ND, Heck DE, Laskin DL, Laskin JD.

J Pharmacol Exp Ther. 2015 Mar;352(3):529-40. doi: 10.1124/jpet.114.221572. Epub 2014 Dec 30.


Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.

Masoud ST, Vecchio LM, Bergeron Y, Hossain MM, Nguyen LT, Bermejo MK, Kile B, Sotnikova TD, Siesser WB, Gainetdinov RR, Wightman RM, Caron MG, Richardson JR, Miller GW, Ramsey AJ, Cyr M, Salahpour A.

Neurobiol Dis. 2015 Feb;74:66-75. doi: 10.1016/j.nbd.2014.10.016. Epub 2014 Oct 30.


Hippocampal ER stress and learning deficits following repeated pyrethroid exposure.

Hossain MM, DiCicco-Bloom E, Richardson JR.

Toxicol Sci. 2015 Jan;143(1):220-8. doi: 10.1093/toxsci/kfu226. Epub 2014 Oct 29.


Role of calcium and calpain in the downregulation of voltage-gated sodium channel expression by the pyrethroid pesticide deltamethrin.

Magby JP, Richardson JR.

J Biochem Mol Toxicol. 2015 Mar;29(3):129-34. doi: 10.1002/jbt.21676. Epub 2014 Oct 30.


Testosterone as the missing link between pesticides, Alzheimer disease, and Parkinson disease--reply.

Richardson JR.

JAMA Neurol. 2014 Sep;71(9):1190. doi: 10.1001/jamaneurol.2014.1814. No abstract available.


Elevated serum DDE and risk for Alzheimer disease--reply.

Richardson JR, Levey AI, German DC.

JAMA Neurol. 2014 Aug;71(8):1056. doi: 10.1001/jamaneurol.2014.1548. No abstract available.


Alzheimer disease risk factors.

Richardson JR, German D, Levey A.

JAMA Neurol. 2014 Aug;71(8):1051. doi: 10.1001/jamaneurol.2014.1525. No abstract available.


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