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Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel.

O'Reilly M, Kirkwood NK, Kenyon EJ, Huckvale R, Cantillon DM, Waddell SJ, Ward SE, Richardson GP, Kros CJ, Derudas M.

J Med Chem. 2019 Jun 13;62(11):5312-5329. doi: 10.1021/acs.jmedchem.8b01325. Epub 2019 May 24.


Alcohol Use Thresholds for Identifying Alcohol-related Problems Before and Following Roux-en-Y Gastric Bypass.

White GE, Courcoulas AP, Richardson GA, Mair C, King WC.

Ann Surg. 2019 Jun;269(6):1001-1009. doi: 10.1097/SLA.0000000000003078.


Do Associations Between Alcohol Use and Alcohol Use Disorder Vary by Weight Status? Results From the National Epidemiologic Survey on Alcohol and Related Conditions-III.

White GE, Richardson GA, Mair C, Courcoulas AP, King WC.

Alcohol Clin Exp Res. 2019 Apr 29. doi: 10.1111/acer.14071. [Epub ahead of print]


Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial.

Peden CJ, Stephens T, Martin G, Kahan BC, Thomson A, Rivett K, Wells D, Richardson G, Kerry S, Bion J, Pearse RM; Enhanced Peri-Operative Care for High-risk patients (EPOCH) trial group.

Lancet. 2019 Jun 1;393(10187):2213-2221. doi: 10.1016/S0140-6736(18)32521-2. Epub 2019 Apr 25.


Correction to: Which Costs Matter? Costs Included in Economic Evaluation and their Impact on Decision Uncertainty for Stable Coronary Artery Disease.

Lomas J, Asaria M, Bojke L, Gale CP, Richardson G, Walker S.

Pharmacoecon Open. 2019 Jun;3(2):277. doi: 10.1007/s41669-019-0129-0.


Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction.

Walaszczyk A, Dookun E, Redgrave R, Tual-Chalot S, Victorelli S, Spyridopoulos I, Owens A, Arthur HM, Passos JF, Richardson GD.

Aging Cell. 2019 Jun;18(3):e12945. doi: 10.1111/acel.12945. Epub 2019 Mar 28.


Creating sustainable health care systems.

Littlejohns P, Kieslich K, Weale A, Tumilty E, Richardson G, Stokes T, Gauld R, Scuffham P.

J Health Organ Manag. 2019 Mar 18;33(1):18-34. doi: 10.1108/JHOM-02-2018-0065. Epub 2018 Nov 22.


Human Cardiac-Mesenchymal Stem Cell-Like Cells, a Novel Cell Population with Therapeutic Potential.

Oldershaw R, Owens WA, Sutherland R, Linney M, Liddle R, Magana L, Lash GE, Gill JH, Richardson G, Meeson A.

Stem Cells Dev. 2019 May 1;28(9):593-607. doi: 10.1089/scd.2018.0170. Epub 2019 Apr 3.


Cerebrovascular Smooth Muscle Cells as the Drivers of Intramural Periarterial Drainage of the Brain.

Aldea R, Weller RO, Wilcock DM, Carare RO, Richardson G.

Front Aging Neurosci. 2019 Jan 23;11:1. doi: 10.3389/fnagi.2019.00001. eCollection 2019.


Length-independent telomere damage drives post-mitotic cardiomyocyte senescence.

Anderson R, Lagnado A, Maggiorani D, Walaszczyk A, Dookun E, Chapman J, Birch J, Salmonowicz H, Ogrodnik M, Jurk D, Proctor C, Correia-Melo C, Victorelli S, Fielder E, Berlinguer-Palmini R, Owens A, Greaves LC, Kolsky KL, Parini A, Douin-Echinard V, LeBrasseur NK, Arthur HM, Tual-Chalot S, Schafer MJ, Roos CM, Miller JD, Robertson N, Mann J, Adams PD, Tchkonia T, Kirkland JL, Mialet-Perez J, Richardson GD, Passos JF.

EMBO J. 2019 Mar 1;38(5). pii: e100492. doi: 10.15252/embj.2018100492. Epub 2019 Feb 8.


Beliefs and attitudes regarding prenatal marijuana use: Perspectives of pregnant women who report use.

Chang JC, Tarr JA, Holland CL, De Genna NM, Richardson GA, Rodriguez KL, Sheeder J, Kraemer KL, Day NL, Rubio D, Jarlenski M, Arnold RM.

Drug Alcohol Depend. 2019 Mar 1;196:14-20. doi: 10.1016/j.drugalcdep.2018.11.028. Epub 2019 Jan 11.


Notes from the Field: Respiratory Syncytial Virus Infections in a Neonatal Intensive Care Unit - Louisiana, December 2017.

Washington EJ, Rose EB, Langley GE, Hand JP, Benowitz I, Gerber SI, Salinas AL, Terry AL, Tonzel JL, Sokol TM, Smith AT, Richardson GJ.

MMWR Morb Mortal Wkly Rep. 2019 Jan 11;68(1):20-21. doi: 10.15585/mmwr.mm6801a5. No abstract available.


Spontaneous Otoacoustic Emissions in TectaY1870C/+ Mice Reflect Changes in Cochlear Amplification and How It Is Controlled by the Tectorial Membrane.

Cheatham MA, Zhou Y, Goodyear RJ, Dallos P, Richardson GP.

eNeuro. 2018 Dec 26;5(6). pii: ENEURO.0314-18.2018. doi: 10.1523/ENEURO.0314-18.2018. eCollection 2018 Nov-Dec.


Prenatal cocaine exposure: Direct and indirect associations with 21-year-old offspring substance use and behavior problems.

Richardson GA, De Genna NM, Goldschmidt L, Larkby C, Donovan JE.

Drug Alcohol Depend. 2019 Feb 1;195:121-131. doi: 10.1016/j.drugalcdep.2018.10.033. Epub 2018 Nov 24.


Hair-Bundle Links: Genetics as the Gateway to Function.

Richardson GP, Petit C.

Cold Spring Harb Perspect Med. 2019 Jan 7. pii: a033142. doi: 10.1101/cshperspect.a033142. [Epub ahead of print]


Enhancing Social-Emotional Health and Wellbeing in the Early Years (E-SEE): a study protocol of a community-based randomised controlled trial with process and economic evaluations of the incredible years infant and toddler parenting programmes, delivered in a proportionate universal model.

Bywater T, Berry V, Blower SL, Cohen J, Gridley N, Kiernan K, Mandefield L, Mason-Jones A, McGilloway S, McKendrick K, Pickett K, Richardson G, Teare MD, Tracey L, Walker S, Whittaker K, Wright J.

BMJ Open. 2018 Dec 19;8(12):e026906. doi: 10.1136/bmjopen-2018-026906.


Quantifying the impact of partial measurement invariance in diagnostic research: An application to addiction research.

Lai MHC, Richardson GB, Mak HW.

Addict Behav. 2019 Jul;94:50-56. doi: 10.1016/j.addbeh.2018.11.029. Epub 2018 Nov 22.


Rapamycin improves healthspan but not inflammaging in nfκb1-/- mice.

Correia-Melo C, Birch J, Fielder E, Rahmatika D, Taylor J, Chapman J, Lagnado A, Carroll BM, Miwa S, Richardson G, Jurk D, Oakley F, Mann J, Mann DA, Korolchuk VI, Passos JF.

Aging Cell. 2019 Feb;18(1):e12882. doi: 10.1111/acel.12882. Epub 2018 Nov 23.


A Risk Assessment Framework for the Socioeconomic Impacts of Electricity Transmission Infrastructure Failure Due to Space Weather: An Application to the United Kingdom.

Oughton EJ, Hapgood M, Richardson GS, Beggan CD, Thomson AWP, Gibbs M, Burnett C, Gaunt CT, Trichas M, Dada R, Horne RB.

Risk Anal. 2019 May;39(5):1022-1043. doi: 10.1111/risa.13229. Epub 2018 Nov 8.


Economic Evaluation of Environmental Interventions: Reflections on Methodological Challenges and Developments.

Bojke L, Schmitt L, Lomas J, Richardson G, Weatherly H.

Int J Environ Res Public Health. 2018 Nov 5;15(11). pii: E2459. doi: 10.3390/ijerph15112459.


Prenatal alcohol exposure and offspring alcohol use and misuse at 22 years of age: A prospective longitudinal study.

Goldschmidt L, Richardson GA, De Genna NM, Cornelius MD, Day NL.

Neurotoxicol Teratol. 2019 Jan - Feb;71:1-5. doi: 10.1016/ Epub 2018 Nov 3.


Alcohol Use Thresholds for Identifying Alcohol-related Problems Before and Following Roux-en-Y Gastric Bypass.

White GE, Courcoulas AP, Richardson GA, Mair C, King WC.

Ann Surg. 2018 Oct 11. doi: 10.1097/SLA.0000000000003078. [Epub ahead of print]


The Role of CD38 on the Function of Regulatory B Cells in a Murine Model of Lupus.

Burlock B, Richardson G, García-Rodríguez S, Guerrero S, Zubiaur M, Sancho J.

Int J Mol Sci. 2018 Sep 25;19(10). pii: E2906. doi: 10.3390/ijms19102906.


Establishing Heat Alert Thresholds for the Varied Climatic Regions of British Columbia, Canada.

McLean KE, Stranberg R, MacDonald M, Richardson GRA, Kosatsky T, Henderson SB.

Int J Environ Res Public Health. 2018 Sep 19;15(9). pii: E2048. doi: 10.3390/ijerph15092048.


Chemotherapy and biologic use in the routine management of metastatic colorectal cancer in Australia: is clinical practice following the evidence?

Semira C, Wong HL, Field K, Lee M, Lee B, Nott L, Shapiro J, Wong R, Tie J, Tran B, Richardson G, Zimet A, Lipton L, Tamjid B, Burge M, Ma B, Johns J, Harold M, Gibbs P.

Intern Med J. 2019 Apr;49(4):446-454. doi: 10.1111/imj.14115.


Trajectories of pre- and postnatal co-use of cannabis and tobacco predict co-use and drug use disorders in adult offspring.

De Genna NM, Goldschmidt L, Richardson GA, Cornelius MD, Day NL.

Neurotoxicol Teratol. 2018 Nov - Dec;70:10-17. doi: 10.1016/ Epub 2018 Sep 15.


A three arm cluster randomised controlled trial to test the effectiveness and cost-effectiveness of the SMART Work & Life intervention for reducing daily sitting time in office workers: study protocol.

Edwardson CL, Biddle SJH, Clarke-Cornwell A, Clemes S, Davies MJ, Dunstan DW, Eborall H, Granat MH, Gray LJ, Healy GN, Richardson G, Yates T, Munir F.

BMC Public Health. 2018 Sep 14;18(1):1120. doi: 10.1186/s12889-018-6017-1.


Situ: Identifying and Explaining Suspicious Behavior in Networks.

Goodall JR, Ragan ED, Steed CA, Reed JW, Richardson GD, Huffer KMT, Bridges RA, Laska JA.

IEEE Trans Vis Comput Graph. 2018 Aug 20. doi: 10.1109/TVCG.2018.2865029. [Epub ahead of print]


Unpredictable movement as an anti-predator strategy.

Richardson G, Dickinson P, Burman OHP, Pike TW.

Proc Biol Sci. 2018 Aug 22;285(1885). pii: 20181112. doi: 10.1098/rspb.2018.1112.


Child maltreatment as a social determinant of midlife health-related quality of life in women: do psychosocial factors explain this association?

Lin HS, Naimi AI, Brooks MM, Richardson GA, Burke JG, Bromberger JT.

Qual Life Res. 2018 Dec;27(12):3243-3254. doi: 10.1007/s11136-018-1937-x. Epub 2018 Aug 18.


Knee motion and muscle activation patterns are altered in hip osteoarthritis: The effect of severity on walking mechanics.

Rutherford D, Buckingham L, Moreside J, Wong I, Richardson G.

Clin Biomech (Bristol, Avon). 2018 Nov;59:1-7. doi: 10.1016/j.clinbiomech.2018.08.001. Epub 2018 Aug 8.


FGFR1-mediated protocadherin-15 loading mediates cargo specificity during intraflagellar transport in inner ear hair-cell kinocilia.

Honda A, Kita T, Seshadri SV, Misaki K, Ahmed Z, Ladbury JE, Richardson GP, Yonemura S, Ladher RK.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8388-8393. doi: 10.1073/pnas.1719861115. Epub 2018 Jul 30.


Early Cannabis Use and Neurocognitive Risk: A Prospective Functional Neuroimaging Study.

Tervo-Clemmens B, Simmonds D, Calabro FJ, Montez DF, Lekht JA, Day NL, Richardson GA, Luna B.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Aug;3(8):713-725. doi: 10.1016/j.bpsc.2018.05.004. Epub 2018 May 29.


An examination of the association between prenatal cocaine exposure and brain activation measures of arousal and attention in young adults: An fMRI study using the Attention Network Task.

Willford JA, Singhabahu D, Herat A, Richardson GA.

Neurotoxicol Teratol. 2018 Sep - Oct;69:1-10. doi: 10.1016/ Epub 2018 Jun 25.


The prognostic value of pain catastrophizing in health-related quality of life judgments after Total knee arthroplasty.

Yakobov E, Stanish W, Tanzer M, Dunbar M, Richardson G, Sullivan MJL.

Health Qual Life Outcomes. 2018 Jun 18;16(1):126. doi: 10.1186/s12955-018-0955-2.


An intervention to support stroke survivors and their carers in the longer term (LoTS2Care): study protocol for a cluster randomised controlled feasibility trial.

Forster A, Hartley S, Barnard L, Ozer S, Hardicre N, Crocker T, Fletcher M, Moreau L, Atkinson R, Hulme C, Holloway I, Schmitt L, House A, Hewison J, Richardson G, Farrin A; LoTS2Care Programme Management Group.

Trials. 2018 Jun 11;19(1):317. doi: 10.1186/s13063-018-2669-5.


Death on the Dome: Epidemiology of Recreational Deaths on Half Dome in Yosemite National Park.

Richardson GD, Spano SJ.

Wilderness Environ Med. 2018 Sep;29(3):338-342. doi: 10.1016/j.wem.2018.04.001. Epub 2018 Jun 7.


Glucocorticoid-induced pancreatic-hepatic trans-differentiation in a human cell line in vitro.

Fairhall EA, Leitch AC, Lakey AF, Probert PME, Richardson G, De Santis C, Wright MC.

Differentiation. 2018 Jul - Aug;102:10-18. doi: 10.1016/j.diff.2018.05.003. Epub 2018 May 22.


Structure, Function, and Development of the Tectorial Membrane: An Extracellular Matrix Essential for Hearing.

Goodyear RJ, Richardson GP.

Curr Top Dev Biol. 2018;130:217-244. doi: 10.1016/bs.ctdb.2018.02.006. Epub 2018 Mar 26.


Stand Out in Class: restructuring the classroom environment to reduce sedentary behaviour in 9-10-year-olds - study protocol for a pilot cluster randomised controlled trial.

Clemes SA, Bingham DD, Pearson N, Chen YL, Edwardson C, McEachan R, Tolfrey K, Cale L, Richardson G, Fray M, Bandelow S, Jaicim NB, Salmon J, Dunstan D, Barber SE.

Pilot Feasibility Stud. 2018 May 24;4:103. doi: 10.1186/s40814-018-0295-3. eCollection 2018.


Prenatal exposures to tobacco and cannabis: Associations with adult electronic cigarette use.

De Genna NM, Richardson GA, Goldschmidt L, Day NL, Cornelius MD.

Drug Alcohol Depend. 2018 Jul 1;188:209-215. doi: 10.1016/j.drugalcdep.2018.03.045. Epub 2018 May 5.


Need for improved public health protection of young people wanting body piercing: evidence from a look-back exercise at a piercing and tattooing premises with poor hygiene practices, Wales (UK) 2015.

Perry M, Lewis H, Thomas DR, Mason B, Richardson G.

Epidemiol Infect. 2018 Jul;146(9):1177-1183. doi: 10.1017/S0950268818001024. Epub 2018 Apr 30.


Higher periprosthetic fracture rate associated with use of modern uncemented stems compared to cemented stems in femoral neck fractures.

Song JSA, Dillman D, Wilson D, Dunbar M, Richardson G.

Hip Int. 2019 Mar;29(2):177-183. doi: 10.1177/1120700018772291. Epub 2018 Apr 23.


The cost-effectiveness of follow-up strategies after cancer treatment: a systematic literature review.

Barbieri M, Richardson G, Paisley S.

Br Med Bull. 2018 Jun 1;126(1):85-100. doi: 10.1093/bmb/ldy011.


A randomized trial of adjunct testosterone for cancer-related muscle loss in men and women.

Wright TJ, Dillon EL, Durham WJ, Chamberlain A, Randolph KM, Danesi C, Horstman AM, Gilkison CR, Willis M, Richardson G, Hatch SS, Jupiter DC, McCammon S, Urban RJ, Sheffield-Moore M.

J Cachexia Sarcopenia Muscle. 2018 Jun;9(3):482-496. doi: 10.1002/jcsm.12295. Epub 2018 Apr 14.


Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells.

Richardson GD, Sage A, Bennaceur K, Al Zhrany N, Coelho-Lima J, Dookun E, Draganova L, Saretzki G, Breault DT, Mallat Z, Spyridopoulos I.

Arterioscler Thromb Vasc Biol. 2018 Jun;38(6):1283-1296. doi: 10.1161/ATVBAHA.117.309940. Epub 2018 Mar 29.


A randomised controlled trial, cost-effectiveness and process evaluation of the implementation of self-management for chronic gastrointestinal disorders in primary care, and linked projects on identification and risk assessment.

Thompson DG, O’Brien S, Kennedy A, Rogers A, Whorwell P, Lovell K, Richardson G, Reeves D, Bower P, Chew-Graham C, Harkness E, Beech P.

Southampton (UK): NIHR Journals Library; 2018 Mar.


Which Costs Matter? Costs Included in Economic Evaluation and their Impact on Decision Uncertainty for Stable Coronary Artery Disease.

Lomas J, Asaria M, Bojke L, Gale CP, Richardson G, Walker S.

Pharmacoecon Open. 2018 Dec;2(4):403-413. doi: 10.1007/s41669-018-0068-1. Erratum in: Pharmacoecon Open. 2019 Apr 2;:.


Editor-in-Chief "Changing of the Guard" Editorial.

Bushnell PJ, Richardson GA.

Neurotoxicol Teratol. 2018 Jan - Feb;65:iii-iv. doi: 10.1016/ No abstract available.


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