Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 464

1.

Overcoming Tamoxifen-Resistance in Estrogen Receptor Positive Breast Cancer Using the Novel Thiosemicarbazone Anti-Cancer Agent, DpC.

Maqbool SN, Lim SC, Park KC, Hanif R, Richardson DR, Jansson PJ, Kovacevic Z.

Br J Pharmacol. 2020 Jan 23. doi: 10.1111/bph.14985. [Epub ahead of print]

PMID:
31975484
2.

Acute Myeloid Leukemia with Co-mutated ASXL1 and SRSF2 Exhibits Monocytic Differentiation and has a Mutational Profile Overlapping with Chronic Myelomonocytic Leukemia.

Johnson SM, Richardson DR, Galeotti J, Esparza S, Zhu A, Fedoriw Y, Weck KE, Foster MC, Coombs CC, Zeidner JF, Montgomery ND.

Hemasphere. 2019 Sep 11;3(5):e292. doi: 10.1097/HS9.0000000000000292. eCollection 2019 Oct. No abstract available.

3.

Regulation of autophagy and apoptosis by Dp44mT-mediated activation of AMPK in pancreatic cancer cells.

Krishan S, Sahni S, Leck LYW, Jansson PJ, Richardson DR.

Biochim Biophys Acta Mol Basis Dis. 2020 Jan 2;1866(5):165657. doi: 10.1016/j.bbadis.2019.165657. [Epub ahead of print]

PMID:
31904416
4.

Novel Multi-Functional Iron Chelators of the Aroyl Nicotinoyl Hydrazone Class that Markedly Enhance Cellular NAD/NADH Ratios.

Wu Z, Palanimuthu D, Braidy N, Salikin NH, Egan S, Huang MLH, Richardson DR.

Br J Pharmacol. 2020 Jan 2. doi: 10.1111/bph.14963. [Epub ahead of print]

PMID:
31895471
5.

Indices of dentate gyrus neurogenesis are unaffected immediately after or following withdrawal from morphine self-administration compared to saline self-administering control male rats.

Bulin SE, Simmons SJ, Richardson DR, Latchney SE, Deutsch HM, Yun S, Eisch AJ.

Behav Brain Res. 2020 Mar 2;381:112448. doi: 10.1016/j.bbr.2019.112448. Epub 2019 Dec 20.

PMID:
31870778
6.

Advances in Genomic Profiling and Risk Stratification in Acute Myeloid Leukemia.

Richardson DR, Foster MC, Coombs CC, Zeidner JF.

Semin Oncol Nurs. 2019 Dec;35(6):150957. doi: 10.1016/j.soncn.2019.150957. Epub 2019 Nov 20. Review.

PMID:
31759819
7.

Thiosemicarbazones suppress expression of the c-Met oncogene by mechanisms involving lysosomal degradation and intracellular shedding.

Park KC, Geleta B, Leck LYW, Paluncic J, Chiang S, Jansson PJ, Kovacevic Z, Richardson DR.

J Biol Chem. 2020 Jan 10;295(2):481-503. doi: 10.1074/jbc.RA119.011341. Epub 2019 Nov 19.

PMID:
31744884
8.

E6AP Promotes a Metastatic Phenotype in Prostate Cancer.

Gamell C, Bandilovska I, Gulati T, Kogan A, Lim SC, Kovacevic Z, Takano EA, Timpone C, Agupitan AD, Litchfield C, Blandino G, Horvath LG, Fox SB, Williams SG, Russo A, Gallo E, Paul PJ, Mitchell C, Sandhu S, Keam SP, Haupt S, Richardson DR, Haupt Y.

iScience. 2019 Dec 20;22:1-15. doi: 10.1016/j.isci.2019.10.065. Epub 2019 Nov 2.

9.

Ascorbate and Tumor Cell Iron Metabolism: The Evolving Story and Its Link to Pathology.

Bae DH, Gholam Azad M, Kalinowski DS, Lane DJR, Jansson PJ, Richardson DR.

Antioxid Redox Signal. 2019 Dec 16. doi: 10.1089/ars.2019.7903. [Epub ahead of print]

PMID:
31672021
10.

Venetoclax-induced tumour lysis syndrome in acute myeloid leukaemia.

Esparza S, Muluneh B, Galeotti J, Matson M, Richardson DR, Montgomery ND, Coombs CC, Jamieson K, Foster MC, Zeidner JF.

Br J Haematol. 2020 Jan;188(1):173-177. doi: 10.1111/bjh.16235. Epub 2019 Oct 16. No abstract available.

PMID:
31621058
11.

Smoking Effects in Foot and Ankle Surgery: An Evidence-Based Review.

Beahrs TR, Reagan J, Bettin CC, Grear BJ, Murphy GA, Richardson DR.

Foot Ankle Int. 2019 Oct;40(10):1226-1232. doi: 10.1177/1071100719867942. Epub 2019 Aug 18.

PMID:
31423824
12.

How iron is handled in the course of heme catabolism: Integration of heme oxygenase with intracellular iron transport mechanisms mediated by poly (rC)-binding protein-2.

Yanatori I, Richardson DR, Toyokuni S, Kishi F.

Arch Biochem Biophys. 2019 Sep 15;672:108071. doi: 10.1016/j.abb.2019.108071. Epub 2019 Aug 14. Review.

PMID:
31421070
13.

Correction: The metastasis suppressor NRDRG1 down-regulates the epidermal growth factor receptor via a lysosomal mechanism by up-regulating mitogen-inducible gene 6.

Menezes SV, Kovacevic Z, Richardson DR.

J Biol Chem. 2019 Aug 2;294(31):11675. doi: 10.1074/jbc.AAC119.010021. No abstract available.

14.

Synthesis, Characterization, and in Vitro Anticancer Activity of Copper and Zinc Bis(Thiosemicarbazone) Complexes.

Anjum R, Palanimuthu D, Kalinowski DS, Lewis W, Park KC, Kovacevic Z, Khan IU, Richardson DR.

Inorg Chem. 2019 Oct 21;58(20):13709-13723. doi: 10.1021/acs.inorgchem.9b01281. Epub 2019 Jul 24.

PMID:
31339305
15.

Laying Down a Solid "Iron Foundation": Professor Erica Baker.

Richardson DR.

Biochim Biophys Acta Gen Subj. 2018 Oct;1862(10):e1-e2. doi: 10.1016/j.bbagen.2018.08.011. Epub 2018 Aug 15. No abstract available.

PMID:
31327464
16.

Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration.

Parkinson CJ, Birrell GW, Chavchich M, Mackenzie D, Haynes RK, de Kock C, Richardson DR, Edstein MD.

J Antimicrob Chemother. 2019 Oct 1;74(10):2965-2973. doi: 10.1093/jac/dkz290.

PMID:
31325302
17.

Trials and Tribulations of Corrected QT Interval Monitoring in Oncology: Rationale for a Practice-Changing Standardized Approach.

Muluneh B, Richardson DR, Hicks C, Jensen BC, Zeidner JF.

J Clin Oncol. 2019 Oct 20;37(30):2719-2721. doi: 10.1200/JCO.19.00922. Epub 2019 Jul 16. No abstract available.

PMID:
31310577
18.

The biochemical and molecular mechanisms involved in the role of tumor micro-environment stress in development of drug resistance.

Al-Akra L, Bae DH, Leck LYW, Richardson DR, Jansson PJ.

Biochim Biophys Acta Gen Subj. 2019 Sep;1863(9):1390-1397. doi: 10.1016/j.bbagen.2019.06.007. Epub 2019 Jun 13. Review.

PMID:
31202693
19.

Side effects from acute myeloid leukemia treatment: results from a national survey.

Crossnohere NL, Richardson DR, Reinhart C, O'Donoghue B, Love SM, Smith BD, Bridges JFP.

Curr Med Res Opin. 2019 Nov;35(11):1965-1970. doi: 10.1080/03007995.2019.1631149. Epub 2019 Jun 26.

PMID:
31188058
20.

Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer.

Park KC, Paluncic J, Kovacevic Z, Richardson DR.

Free Radic Biol Med. 2019 May 24. pii: S0891-5849(19)30256-4. doi: 10.1016/j.freeradbiomed.2019.05.020. [Epub ahead of print] Review.

PMID:
31132412
21.

The Role of the Antioxidant Response in Mitochondrial Dysfunction in Degenerative Diseases: Cross-Talk between Antioxidant Defense, Autophagy, and Apoptosis.

Huang ML, Chiang S, Kalinowski DS, Bae DH, Sahni S, Richardson DR.

Oxid Med Cell Longev. 2019 Apr 7;2019:6392763. doi: 10.1155/2019/6392763. eCollection 2019. Review.

22.

Tumor-induced neoangiogenesis and receptor tyrosine kinases - Mechanisms and strategies for acquired resistance.

Yunus M, Jansson PJ, Kovacevic Z, Kalinowski DS, Richardson DR.

Biochim Biophys Acta Gen Subj. 2019 Jul;1863(7):1217-1225. doi: 10.1016/j.bbagen.2019.04.017. Epub 2019 Apr 25. Review.

PMID:
31029846
23.

The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response.

Merlot AM, Porter GM, Sahni S, Lim EG, Peres P, Richardson DR.

Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2094-2110. doi: 10.1016/j.bbadis.2019.04.007. Epub 2019 Apr 11.

PMID:
30981813
24.

Novel SPME fibers based on a plastic support for determination of plasma protein binding of thiosemicarbazone metal chelators: a case example of DpC, an anti-cancer drug that entered clinical trials.

Reimerová P, Stariat J, Bavlovič Piskáčková H, Jansová H, Roh J, Kalinowski DS, Macháček M, Šimůnek T, Richardson DR, Štěrbová-Kovaříková P.

Anal Bioanal Chem. 2019 Apr;411(11):2383-2394. doi: 10.1007/s00216-019-01681-w. Epub 2019 Mar 1.

PMID:
30820631
25.

Two mechanisms involving the autophagic and proteasomal pathways process the metastasis suppressor protein, N-myc downstream regulated gene 1.

Sahni S, Park KC, Kovacevic Z, Richardson DR.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1361-1378. doi: 10.1016/j.bbadis.2019.02.008. Epub 2019 Feb 11.

PMID:
30763642
26.

Psychiatric Care in Hematopoietic Stem Cell Transplantation.

Nakamura ZM, Nash RP, Quillen LJ, Richardson DR, McCall RC, Park EM.

Psychosomatics. 2019 May - Jun;60(3):227-237. doi: 10.1016/j.psym.2019.01.005. Epub 2019 Jan 19. Review.

PMID:
30733043
27.

The metastasis suppressor NDRG1 down-regulates the epidermal growth factor receptor via a lysosomal mechanism by up-regulating mitogen-inducible gene 6.

Menezes SV, Kovacevic Z, Richardson DR.

J Biol Chem. 2019 Mar 15;294(11):4045-4064. doi: 10.1074/jbc.RA118.006279. Epub 2019 Jan 24. Erratum in: J Biol Chem. 2019 Aug 2;294(31):11675.

PMID:
30679310
28.

The metastasis suppressor, NDRG1, attenuates oncogenic TGF-β and NF-κB signaling to enhance membrane E-cadherin expression in pancreatic cancer cells.

Menezes SV, Fouani L, Huang MLH, Geleta B, Maleki S, Richardson A, Richardson DR, Kovacevic Z.

Carcinogenesis. 2019 Jul 6;40(6):805-818. doi: 10.1093/carcin/bgy178.

PMID:
30561520
29.

Pharmacological targeting of mitochondria in cancer stem cells: An ancient organelle at the crossroad of novel anti-cancer therapies.

Skoda J, Borankova K, Jansson PJ, Huang ML, Veselska R, Richardson DR.

Pharmacol Res. 2019 Jan;139:298-313. doi: 10.1016/j.phrs.2018.11.020. Epub 2018 Nov 16. Review.

PMID:
30453033
30.

Single-camera, single-shot, time-resolved laser-induced incandescence decay imaging.

Chen Y, Cenker E, Richardson DR, Kearney SP, Halls BR, Skeen SA, Shaddix CR, Guildenbecher DR.

Opt Lett. 2018 Nov 1;43(21):5363-5366. doi: 10.1364/OL.43.005363.

PMID:
30383008
31.

Publisher Correction: Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive.

Yun S, Reynolds RP, Petrof I, White A, Rivera PD, Segev A, Gibson AD, Suarez M, DeSalle MJ, Ito N, Mukherjee S, Richardson DR, Kang CE, Ahrens-Nicklas RC, Soler I, Chetkovich DM, Kourrich S, Coulter DA, Eisch AJ.

Nat Med. 2018 Sep;24(9):1482. doi: 10.1038/s41591-018-0084-9.

PMID:
29934536
32.

The old and new biochemistry of polyamines.

Bae DH, Lane DJR, Jansson PJ, Richardson DR.

Biochim Biophys Acta Gen Subj. 2018 Sep;1862(9):2053-2068. doi: 10.1016/j.bbagen.2018.06.004. Epub 2018 Jun 8. Review.

PMID:
29890242
33.

A challenge to discriminating psychosocial eligibility criteria: exploring the ethical justification for excluding patients with psychosocial risk factors from hematopoietic cell transplantation.

Richardson DR, Devine SM, Nash R.

Bone Marrow Transplant. 2018 Nov;53(11):1474-1477. doi: 10.1038/s41409-018-0213-6. Epub 2018 Jun 6. No abstract available.

PMID:
29875374
34.

Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes.

Lane DJR, Bae DH, Siafakas AR, Suryo Rahmanto Y, Al-Akra L, Jansson PJ, Casero RA Jr, Richardson DR.

Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2793-2813. doi: 10.1016/j.bbadis.2018.05.007. Epub 2018 May 16.

35.

Novel chelators based on adamantane-derived semicarbazones and hydrazones that target multiple hallmarks of Alzheimer's disease.

Palanimuthu D, Wu Z, Jansson PJ, Braidy N, Bernhardt PV, Richardson DR, Kalinowski DS.

Dalton Trans. 2018 May 29;47(21):7190-7205. doi: 10.1039/c8dt01099d.

PMID:
29749416
36.

Identification of differential phosphorylation and sub-cellular localization of the metastasis suppressor, NDRG1.

Park KC, Menezes SV, Kalinowski DS, Sahni S, Jansson PJ, Kovacevic Z, Richardson DR.

Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2644-2663. doi: 10.1016/j.bbadis.2018.04.011. Epub 2018 Apr 19.

37.

Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive.

Yun S, Reynolds RP, Petrof I, White A, Rivera PD, Segev A, Gibson AD, Suarez M, DeSalle MJ, Ito N, Mukherjee S, Richardson DR, Kang CE, Ahrens-Nicklas RC, Soler I, Chetkovich DM, Kourrich S, Coulter DA, Eisch AJ.

Nat Med. 2018 May;24(5):658-666. doi: 10.1038/s41591-018-0002-1. Epub 2018 Apr 16. Erratum in: Nat Med. 2018 Sep;24(9):1482.

38.

Ironing out the role of the cyclin-dependent kinase inhibitor, p21 in cancer: Novel iron chelating agents to target p21 expression and activity.

Moussa RS, Park KC, Kovacevic Z, Richardson DR.

Free Radic Biol Med. 2019 Mar;133:276-294. doi: 10.1016/j.freeradbiomed.2018.03.027. Epub 2018 Mar 20. Review.

PMID:
29572098
39.

Psychosocial risk predicts high readmission rates for hematopoietic cell transplant recipients.

Richardson DR, Huang Y, McGinty HL, Elder P, Newlin J, Kirkendall C, Andritsos L, Benson D, Blum W, Efebera Y, Penza S, Hofmeister C, Jaglowski S, Klisovic R, Vasu S, William B, Devine S, Rosko AE.

Bone Marrow Transplant. 2018 Nov;53(11):1418-1427. doi: 10.1038/s41409-018-0118-4. Epub 2018 Feb 14.

40.

Phase conjugate digital inline holography (PCDIH).

Guildenbecher DR, Hoffmeister KNG, Kunzler WM, Richardson DR, Kearney SP.

Opt Lett. 2018 Feb 15;43(4):803-806. doi: 10.1364/OL.43.000803.

PMID:
29443998
41.

Tumor stressors induce two mechanisms of intracellular P-glycoprotein-mediated resistance that are overcome by lysosomal-targeted thiosemicarbazones.

Al-Akra L, Bae DH, Sahni S, Huang MLH, Park KC, Lane DJR, Jansson PJ, Richardson DR.

J Biol Chem. 2018 Mar 9;293(10):3562-3587. doi: 10.1074/jbc.M116.772699. Epub 2018 Jan 5.

42.

Targeting Oncogenic Nuclear Factor Kappa B Signaling with Redox-Active Agents for Cancer Treatment.

Fouani L, Kovacevic Z, Richardson DR.

Antioxid Redox Signal. 2019 Mar 10;30(8):1096-1123. doi: 10.1089/ars.2017.7387. Epub 2018 Feb 6.

PMID:
29161883
43.

Transcriptional regulation of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by the chelator, Dp44mT.

Moussa RS, Kovacevic Z, Bae DH, Lane DJR, Richardson DR.

Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):761-774. doi: 10.1016/j.bbagen.2017.10.009. Epub 2017 Oct 13.

PMID:
29032246
44.

Mixture-fraction imaging at 1  kHz using femtosecond laser-induced fluorescence of krypton.

Richardson DR, Jiang N, Stauffer HU, Kearney SP, Roy S, Gord JR.

Opt Lett. 2017 Sep 1;42(17):3498-3501. doi: 10.1364/OL.42.003498.

PMID:
28957072
45.

Whole-Body Exposure to 28Si-Radiation Dose-Dependently Disrupts Dentate Gyrus Neurogenesis and Proliferation in the Short Term and New Neuron Survival and Contextual Fear Conditioning in the Long Term.

Whoolery CW, Walker AK, Richardson DR, Lucero MJ, Reynolds RP, Beddow DH, Clark KL, Shih HY, LeBlanc JA, Cole MG, Amaral WZ, Mukherjee S, Zhang S, Ahn F, Bulin SE, DeCarolis NA, Rivera PD, Chen BPC, Yun S, Eisch AJ.

Radiat Res. 2017 Nov;188(5):532-551. doi: 10.1667/RR14797.1. Epub 2017 Sep 25.

46.

Molecular Alterations in a Mouse Cardiac Model of Friedreich Ataxia: An Impaired Nrf2 Response Mediated via Upregulation of Keap1 and Activation of the Gsk3β Axis.

Anzovino A, Chiang S, Brown BE, Hawkins CL, Richardson DR, Huang ML.

Am J Pathol. 2017 Dec;187(12):2858-2875. doi: 10.1016/j.ajpath.2017.08.021. Epub 2017 Sep 19.

47.

A novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's disease.

Palanimuthu D, Poon R, Sahni S, Anjum R, Hibbs D, Lin HY, Bernhardt PV, Kalinowski DS, Richardson DR.

Eur J Med Chem. 2017 Oct 20;139:612-632. doi: 10.1016/j.ejmech.2017.08.021. Epub 2017 Aug 9.

PMID:
28841514
48.

Mitochondrial dysfunction in the neuro-degenerative and cardio-degenerative disease, Friedreich's ataxia.

Chiang S, Kalinowski DS, Jansson PJ, Richardson DR, Huang ML.

Neurochem Int. 2018 Jul;117:35-48. doi: 10.1016/j.neuint.2017.08.002. Epub 2017 Aug 4. Review.

PMID:
28782591
49.

Bilateral uveitis associated with nivolumab therapy for metastatic melanoma: a case report.

Richardson DR, Ellis B, Mehmi I, Leys M.

Int J Ophthalmol. 2017 Jul 18;10(7):1183-1186. doi: 10.18240/ijo.2017.07.28. eCollection 2017. No abstract available.

50.

Exploiting Cancer Metal Metabolism using Anti-Cancer Metal- Binding Agents.

Merlot AM, Kalinowski DS, Kovacevic Z, Jansson PJ, Sahni S, Huang ML, Lane DJR, Lok H, Richardson DR.

Curr Med Chem. 2019;26(2):302-322. doi: 10.2174/0929867324666170705120809. Review.

PMID:
28685681

Supplemental Content

Loading ...
Support Center