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Items: 1 to 50 of 447

1.

The biochemical and molecular mechanisms involved in the role of micro-tumor environment stress in development of drug resistance.

Al-Akra L, Bae DH, Leck LL, Richardson DR, Jansson PJ.

Biochim Biophys Acta Gen Subj. 2019 Jun 13. pii: S0304-4165(19)30156-4. doi: 10.1016/j.bbagen.2019.06.007. [Epub ahead of print] Review.

PMID:
31202693
2.

Side effects from acute myeloid leukemia treatment: results from a national survey.

Crossnohere NL, Richardson DR, Reinhart C, O'Donoghue B, Love SM, Smith BD, Bridges JF.

Curr Med Res Opin. 2019 Jun 12:1. doi: 10.1080/03007995.2019.1631149. [Epub ahead of print]

PMID:
31188058
3.

Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer.

Chan Park K, Paluncic J, Kovacevic Z, Richardson DR.

Free Radic Biol Med. 2019 May 24. pii: S0891-5849(19)30256-4. doi: 10.1016/j.freeradbiomed.2019.05.020. [Epub ahead of print] Review.

PMID:
31132412
4.

The Role of the Antioxidant Response in Mitochondrial Dysfunction in Degenerative Diseases: Cross-Talk between Antioxidant Defense, Autophagy, and Apoptosis.

Huang ML, Chiang S, Kalinowski DS, Bae DH, Sahni S, Richardson DR.

Oxid Med Cell Longev. 2019 Apr 7;2019:6392763. doi: 10.1155/2019/6392763. eCollection 2019. Review.

5.

Tumor-induced neoangiogenesis and receptor tyrosine kinases - Mechanisms and strategies for acquired resistance.

Yunus M, Jansson PJ, Kovacevic Z, Kalinowski DS, Richardson DR.

Biochim Biophys Acta Gen Subj. 2019 Jul;1863(7):1217-1225. doi: 10.1016/j.bbagen.2019.04.017. Epub 2019 Apr 25. Review.

PMID:
31029846
6.

The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response.

Merlot AM, Porter GM, Sahni S, Lim EG, Peres P, Richardson DR.

Biochim Biophys Acta Mol Basis Dis. 2019 Apr 11. pii: S0925-4439(19)30118-8. doi: 10.1016/j.bbadis.2019.04.007. [Epub ahead of print]

PMID:
30981813
7.

Novel SPME fibers based on a plastic support for determination of plasma protein binding of thiosemicarbazone metal chelators: a case example of DpC, an anti-cancer drug that entered clinical trials.

Reimerová P, Stariat J, Bavlovič Piskáčková H, Jansová H, Roh J, Kalinowski DS, Macháček M, Šimůnek T, Richardson DR, Štěrbová-Kovaříková P.

Anal Bioanal Chem. 2019 Apr;411(11):2383-2394. doi: 10.1007/s00216-019-01681-w. Epub 2019 Mar 1.

PMID:
30820631
8.

Two mechanisms involving the autophagic and proteasomal pathways process the metastasis suppressor protein, N-myc downstream regulated gene 1.

Sahni S, Park KC, Kovacevic Z, Richardson DR.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1361-1378. doi: 10.1016/j.bbadis.2019.02.008. Epub 2019 Feb 11.

PMID:
30763642
9.

Psychiatric Care in Hematopoietic Stem Cell Transplantation.

Nakamura ZM, Nash RP, Quillen LJ, Richardson DR, McCall RC, Park EM.

Psychosomatics. 2019 May - Jun;60(3):227-237. doi: 10.1016/j.psym.2019.01.005. Epub 2019 Jan 19. Review.

PMID:
30733043
10.

The metastasis suppressor NDRG1 down-regulates the epidermal growth factor receptor via a lysosomal mechanism by up-regulating mitogen-inducible gene 6.

Menezes SV, Kovacevic Z, Richardson DR.

J Biol Chem. 2019 Mar 15;294(11):4045-4064. doi: 10.1074/jbc.RA118.006279. Epub 2019 Jan 24.

PMID:
30679310
11.

The Metastasis Suppressor, NDRG1, Attenuates Oncogenic TGF-β and NF-ĸB Signaling to Enhance Membrane E-Cadherin Expression in Pancreatic Cancer Cells.

Menezes SV, Fouani L, Huang MLH, Geleta B, Maleki S, Richardson A, Richardson DR, Kovacevic Z.

Carcinogenesis. 2018 Dec 18. doi: 10.1093/carcin/bgy178. [Epub ahead of print]

PMID:
30561520
12.

Pharmacological targeting of mitochondria in cancer stem cells: An ancient organelle at the crossroad of novel anti-cancer therapies.

Skoda J, Borankova K, Jansson PJ, Huang ML, Veselska R, Richardson DR.

Pharmacol Res. 2019 Jan;139:298-313. doi: 10.1016/j.phrs.2018.11.020. Epub 2018 Nov 16. Review.

PMID:
30453033
13.

Single-camera, single-shot, time-resolved laser-induced incandescence decay imaging.

Chen Y, Cenker E, Richardson DR, Kearney SP, Halls BR, Skeen SA, Shaddix CR, Guildenbecher DR.

Opt Lett. 2018 Nov 1;43(21):5363-5366. doi: 10.1364/OL.43.005363.

PMID:
30383008
14.

Publisher Correction: Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive.

Yun S, Reynolds RP, Petrof I, White A, Rivera PD, Segev A, Gibson AD, Suarez M, DeSalle MJ, Ito N, Mukherjee S, Richardson DR, Kang CE, Ahrens-Nicklas RC, Soler I, Chetkovich DM, Kourrich S, Coulter DA, Eisch AJ.

Nat Med. 2018 Sep;24(9):1482. doi: 10.1038/s41591-018-0084-9.

PMID:
29934536
15.

The old and new biochemistry of polyamines.

Bae DH, Lane DJR, Jansson PJ, Richardson DR.

Biochim Biophys Acta Gen Subj. 2018 Sep;1862(9):2053-2068. doi: 10.1016/j.bbagen.2018.06.004. Epub 2018 Jun 8. Review.

PMID:
29890242
16.

A challenge to discriminating psychosocial eligibility criteria: exploring the ethical justification for excluding patients with psychosocial risk factors from hematopoietic cell transplantation.

Richardson DR, Devine SM, Nash R.

Bone Marrow Transplant. 2018 Nov;53(11):1474-1477. doi: 10.1038/s41409-018-0213-6. Epub 2018 Jun 6. No abstract available.

PMID:
29875374
17.

Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes.

Lane DJR, Bae DH, Siafakas AR, Suryo Rahmanto Y, Al-Akra L, Jansson PJ, Casero RA Jr, Richardson DR.

Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2793-2813. doi: 10.1016/j.bbadis.2018.05.007. Epub 2018 May 16.

PMID:
29777905
18.

Novel chelators based on adamantane-derived semicarbazones and hydrazones that target multiple hallmarks of Alzheimer's disease.

Palanimuthu D, Wu Z, Jansson PJ, Braidy N, Bernhardt PV, Richardson DR, Kalinowski DS.

Dalton Trans. 2018 May 29;47(21):7190-7205. doi: 10.1039/c8dt01099d.

PMID:
29749416
19.

Identification of differential phosphorylation and sub-cellular localization of the metastasis suppressor, NDRG1.

Park KC, Menezes SV, Kalinowski DS, Sahni S, Jansson PJ, Kovacevic Z, Richardson DR.

Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2644-2663. doi: 10.1016/j.bbadis.2018.04.011. Epub 2018 Apr 19.

PMID:
29679718
20.

Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive.

Yun S, Reynolds RP, Petrof I, White A, Rivera PD, Segev A, Gibson AD, Suarez M, DeSalle MJ, Ito N, Mukherjee S, Richardson DR, Kang CE, Ahrens-Nicklas RC, Soler I, Chetkovich DM, Kourrich S, Coulter DA, Eisch AJ.

Nat Med. 2018 May;24(5):658-666. doi: 10.1038/s41591-018-0002-1. Epub 2018 Apr 16. Erratum in: Nat Med. 2018 Sep;24(9):1482.

21.

Ironing out the role of the cyclin-dependent kinase inhibitor, p21 in cancer: Novel iron chelating agents to target p21 expression and activity.

Moussa RS, Park KC, Kovacevic Z, Richardson DR.

Free Radic Biol Med. 2019 Mar;133:276-294. doi: 10.1016/j.freeradbiomed.2018.03.027. Epub 2018 Mar 20. Review.

PMID:
29572098
22.

Psychosocial risk predicts high readmission rates for hematopoietic cell transplant recipients.

Richardson DR, Huang Y, McGinty HL, Elder P, Newlin J, Kirkendall C, Andritsos L, Benson D, Blum W, Efebera Y, Penza S, Hofmeister C, Jaglowski S, Klisovic R, Vasu S, William B, Devine S, Rosko AE.

Bone Marrow Transplant. 2018 Nov;53(11):1418-1427. doi: 10.1038/s41409-018-0118-4. Epub 2018 Feb 14.

23.

Phase conjugate digital inline holography (PCDIH).

Guildenbecher DR, Hoffmeister KNG, Kunzler WM, Richardson DR, Kearney SP.

Opt Lett. 2018 Feb 15;43(4):803-806. doi: 10.1364/OL.43.000803.

PMID:
29443998
24.

Tumor stressors induce two mechanisms of intracellular P-glycoprotein-mediated resistance that are overcome by lysosomal-targeted thiosemicarbazones.

Al-Akra L, Bae DH, Sahni S, Huang MLH, Park KC, Lane DJR, Jansson PJ, Richardson DR.

J Biol Chem. 2018 Mar 9;293(10):3562-3587. doi: 10.1074/jbc.M116.772699. Epub 2018 Jan 5.

25.

Targeting Oncogenic Nuclear Factor Kappa B Signaling with Redox-Active Agents for Cancer Treatment.

Fouani L, Kovacevic Z, Richardson DR.

Antioxid Redox Signal. 2019 Mar 10;30(8):1096-1123. doi: 10.1089/ars.2017.7387. Epub 2018 Feb 6.

PMID:
29161883
26.

Transcriptional regulation of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by the chelator, Dp44mT.

Moussa RS, Kovacevic Z, Bae DH, Lane DJR, Richardson DR.

Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):761-774. doi: 10.1016/j.bbagen.2017.10.009. Epub 2017 Oct 13.

PMID:
29032246
27.

Mixture-fraction imaging at 1  kHz using femtosecond laser-induced fluorescence of krypton.

Richardson DR, Jiang N, Stauffer HU, Kearney SP, Roy S, Gord JR.

Opt Lett. 2017 Sep 1;42(17):3498-3501. doi: 10.1364/OL.42.003498.

PMID:
28957072
28.

Whole-Body Exposure to 28Si-Radiation Dose-Dependently Disrupts Dentate Gyrus Neurogenesis and Proliferation in the Short Term and New Neuron Survival and Contextual Fear Conditioning in the Long Term.

Whoolery CW, Walker AK, Richardson DR, Lucero MJ, Reynolds RP, Beddow DH, Clark KL, Shih HY, LeBlanc JA, Cole MG, Amaral WZ, Mukherjee S, Zhang S, Ahn F, Bulin SE, DeCarolis NA, Rivera PD, Chen BPC, Yun S, Eisch AJ.

Radiat Res. 2017 Nov;188(5):532-551. doi: 10.1667/RR14797.1. Epub 2017 Sep 25.

29.

Molecular Alterations in a Mouse Cardiac Model of Friedreich Ataxia: An Impaired Nrf2 Response Mediated via Upregulation of Keap1 and Activation of the Gsk3β Axis.

Anzovino A, Chiang S, Brown BE, Hawkins CL, Richardson DR, Huang ML.

Am J Pathol. 2017 Dec;187(12):2858-2875. doi: 10.1016/j.ajpath.2017.08.021. Epub 2017 Sep 19.

PMID:
28935570
30.

A novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's disease.

Palanimuthu D, Poon R, Sahni S, Anjum R, Hibbs D, Lin HY, Bernhardt PV, Kalinowski DS, Richardson DR.

Eur J Med Chem. 2017 Oct 20;139:612-632. doi: 10.1016/j.ejmech.2017.08.021. Epub 2017 Aug 9.

PMID:
28841514
31.

Mitochondrial dysfunction in the neuro-degenerative and cardio-degenerative disease, Friedreich's ataxia.

Chiang S, Kalinowski DS, Jansson PJ, Richardson DR, Huang ML.

Neurochem Int. 2018 Jul;117:35-48. doi: 10.1016/j.neuint.2017.08.002. Epub 2017 Aug 4. Review.

PMID:
28782591
32.

Bilateral uveitis associated with nivolumab therapy for metastatic melanoma: a case report.

Richardson DR, Ellis B, Mehmi I, Leys M.

Int J Ophthalmol. 2017 Jul 18;10(7):1183-1186. doi: 10.18240/ijo.2017.07.28. eCollection 2017. No abstract available.

33.

Exploiting Cancer Metal Metabolism using Anti-Cancer Metal- Binding Agents.

Merlot AM, Kalinowski DS, Kovacevic Z, Jansson PJ, Sahni S, Huang ML, Lane DJR, Lok H, Richardson DR.

Curr Med Chem. 2019;26(2):302-322. doi: 10.2174/0929867324666170705120809. Review.

PMID:
28685681
34.

The iron chaperone poly(rC)-binding protein 2 forms a metabolon with the heme oxygenase 1/cytochrome P450 reductase complex for heme catabolism and iron transfer.

Yanatori I, Richardson DR, Toyokuni S, Kishi F.

J Biol Chem. 2017 Aug 11;292(32):13205-13229. doi: 10.1074/jbc.M117.776021. Epub 2017 Jun 27.

35.

Dentate gyrus neurogenesis ablation via cranial irradiation enhances morphine self-administration and locomotor sensitization.

Bulin SE, Mendoza ML, Richardson DR, Song KH, Solberg TD, Yun S, Eisch AJ.

Addict Biol. 2018 Mar;23(2):665-675. doi: 10.1111/adb.12524. Epub 2017 Jun 19.

36.

Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling.

Menezes SV, Sahni S, Kovacevic Z, Richardson DR.

J Biol Chem. 2017 Aug 4;292(31):12772-12782. doi: 10.1074/jbc.R117.776393. Epub 2017 Jun 14. Review.

37.

Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy.

Shi L, Ito F, Wang Y, Okazaki Y, Tanaka H, Mizuno M, Hori M, Hirayama T, Nagasawa H, Richardson DR, Toyokuni S.

Free Radic Biol Med. 2017 Jul;108:904-917. doi: 10.1016/j.freeradbiomed.2017.04.368. Epub 2017 May 2.

PMID:
28465262
38.

Preoperative Risk Factors for Complications in Elective Ankle and Hindfoot Reconstruction.

Mulligan RP, McCarthy KJ, Grear BJ, Richardson DR, Ishikawa SN, Murphy GA.

Foot Ankle Spec. 2018 Feb;11(1):54-60. doi: 10.1177/1938640017706155. Epub 2017 Apr 20.

PMID:
28423940
39.

Comparison of chirped-probe-pulse and hybrid femtosecond/picosecond coherent anti-Stokes Raman scattering for combustion thermometry.

Richardson DR, Stauffer HU, Roy S, Gord JR.

Appl Opt. 2017 Apr 10;56(11):E37-E49. doi: 10.1364/AO.56.000E37.

PMID:
28414340
40.

Novel Thiosemicarbazones Inhibit Lysine-Rich Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) Coisolated (LYRIC) and the LYRIC-Induced Epithelial-Mesenchymal Transition via Upregulation of N-Myc Downstream-Regulated Gene 1 (NDRG1).

Xi R, Pun IH, Menezes SV, Fouani L, Kalinowski DS, Huang ML, Zhang X, Richardson DR, Kovacevic Z.

Mol Pharmacol. 2017 May;91(5):499-517. doi: 10.1124/mol.116.107870. Epub 2017 Mar 8.

PMID:
28275050
41.

Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1.

Kovacevic Z, Sahni S, Lok H, Davies MJ, Wink DA, Richardson DR.

Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt A):995-999. doi: 10.1016/j.bbagen.2017.02.021. Epub 2017 Feb 17. Review.

PMID:
28219722
42.

Femtosecond, two-photon, planar laser-induced fluorescence of carbon monoxide in flames.

Richardson DR, Roy S, Gord JR.

Opt Lett. 2017 Feb 15;42(4):875-878. doi: 10.1364/OL.42.000875.

PMID:
28198887
43.

The mechanistic role of chemically diverse metal ions in the induction of autophagy.

Sahni S, Bae DH, Jansson PJ, Richardson DR.

Pharmacol Res. 2017 May;119:118-127. doi: 10.1016/j.phrs.2017.01.009. Epub 2017 Jan 10. Review.

PMID:
28087444
44.

Metals and metastasis: Exploiting the role of metals in cancer metastasis to develop novel anti-metastatic agents.

Fouani L, Menezes SV, Paulson M, Richardson DR, Kovacevic Z.

Pharmacol Res. 2017 Jan;115:275-287. doi: 10.1016/j.phrs.2016.12.001. Epub 2016 Dec 7. Review.

PMID:
27940016
46.

A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity.

Lok HC, Sahni S, Jansson PJ, Kovacevic Z, Hawkins CL, Richardson DR.

J Biol Chem. 2016 Dec 30;291(53):27042-27061. doi: 10.1074/jbc.M116.763714. Epub 2016 Nov 19.

47.

Letter to the Editor: "Analysis of the Interaction of Dp44mT with Human Serum Albumin and Calf Thymus DNA Using Molecular Docking and Spectroscopic Techniques".

Merlot AM, Sahni S, Lane DJ, Richardson V, Huang ML, Kalinowski DS, Richardson DR.

Int J Mol Sci. 2016 Nov 16;17(11). pii: E1916.

48.

Congenital Paradoxical Lower Eyelid Retraction With Upgaze due to an Anomalous Extraocular Muscle.

Richardson DR, Gadzala LA, Bonsall DJ, Hogg JP, Williams HJ, Nguyen J.

Ophthalmic Plast Reconstr Surg. 2017 Jul/Aug;33(4):e101-e102. doi: 10.1097/IOP.0000000000000809.

PMID:
27811631
49.

The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells.

Krishan S, Richardson DR, Sahni S.

Biochim Biophys Acta. 2016 Dec;1863(12):2916-2933. doi: 10.1016/j.bbamcr.2016.09.011. Epub 2016 Sep 15.

50.

Orthopedic Surgical Options for Joint Cartilage Repair and Restoration.

Ruta DJ, Villarreal AD, Richardson DR.

Phys Med Rehabil Clin N Am. 2016 Nov;27(4):1019-1042. doi: 10.1016/j.pmr.2016.06.007. Review.

PMID:
27788899

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