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Development of an integrated multimodal optical imaging system with real-time image analysis for the evaluation of oral premalignant lesions.

Yang EC, Vohra IS, Badaoui H, Schwarz RA, Cherry KD, Quang T, Jacob J, Lang A, Bass N, Rodriguez J, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum RR.

J Biomed Opt. 2019 Feb;24(2):1-10. doi: 10.1117/1.JBO.24.2.025003.


Low-Cost Instructional Apparatus to Improve Training for Cervical Cancer Screening and Prevention.

Parra S, Oden M, Schmeler K, Richards-Kortum R; Rice360 Student Team,.

Obstet Gynecol. 2019 Mar;133(3):559-567. doi: 10.1097/AOG.0000000000003140.


A mobile-phone based high-resolution microendoscope to image cervical precancer.

Grant BD, Quang T, Possati-Resende JC, Scapulatempo-Neto C, de Macedo Matsushita G, Mauad EC, Stoler MH, Castle PE, Guerreiro Fregnani JHT, Schmeler KM, Richards-Kortum R.

PLoS One. 2019 Feb 6;14(2):e0211045. doi: 10.1371/journal.pone.0211045. eCollection 2019.


Improving nuclear morphometry imaging with real-time and low-cost line-scanning confocal microendoscope.

Tang Y, Kortum A, Vohra I, Othman M, Dhingra S, Mansour N, Carns J, Anandasabapathy S, Richards-Kortum R.

Opt Lett. 2019 Feb 1;44(3):654-657. doi: 10.1364/OL.44.000654.


Quantitative analysis of in vivo high-resolution microendoscopic images for the detection of neoplastic colorectal polyps.

Tang Y, Polydorides AD, Anandasabapathy S, Richards-Kortum RR.

J Biomed Opt. 2018 Nov;23(11):1-6. doi: 10.1117/1.JBO.23.11.116003.


Is Proflavine Exposure Associated with Disease Progression in Women with Cervical Dysplasia? A Brief Report.

Pantano N, Hunt B, Schwarz RA, Parra S, Cherry K, Possati-Resende JC, Longatto-Filho A, Fregnani JHTG, Castle PE, Schmeler K, Richards-Kortum R.

Photochem Photobiol. 2018 Nov;94(6):1308-1313. doi: 10.1111/php.12976. Epub 2018 Jul 31.


In Vivo Multimodal Optical Imaging: Improved Detection of Oral Dysplasia in Low-Risk Oral Mucosal Lesions.

Yang EC, Schwarz RA, Lang AK, Bass N, Badaoui H, Vohra IS, Cherry KD, Williams MD, Gillenwater AM, Vigneswaran N, Richards-Kortum RR.

Cancer Prev Res (Phila). 2018 Aug;11(8):465-476. doi: 10.1158/1940-6207.CAPR-18-0032. Epub 2018 Jun 14.


Noninvasive diagnostic adjuncts for the evaluation of potentially premalignant oral epithelial lesions: current limitations and future directions.

Yang EC, Tan MT, Schwarz RA, Richards-Kortum RR, Gillenwater AM, Vigneswaran N.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Jun;125(6):670-681. doi: 10.1016/j.oooo.2018.02.020. Epub 2018 Mar 9. Review.


Optical imaging with a high-resolution microendoscope to identify sinonasal pathology.

Kidwai SM, Parasher AK, Schorn VJ, Demicco EG, Richards-Kortum R, Iloreta AM, Govindaraj S, Miles BA.

Am J Otolaryngol. 2018 Jul - Aug;39(4):383-387. doi: 10.1016/j.amjoto.2018.03.025. Epub 2018 Mar 20.


Diagnosing Cervical Neoplasia in Rural Brazil Using a Mobile Van Equipped with In Vivo Microscopy: A Cluster-Randomized Community Trial.

Hunt B, Fregnani JHTG, Schwarz RA, Pantano N, Tesoni S, Possati-Resende JC, Antoniazzi M, de Oliveira Fonseca B, de Macêdo Matsushita G, Scapulatempo-Neto C, Kerr L, Castle PE, Schmeler K, Richards-Kortum R.

Cancer Prev Res (Phila). 2018 Jun;11(6):359-370. doi: 10.1158/1940-6207.CAPR-17-0265. Epub 2018 Apr 4.


Impact of hypothermia on implementation of CPAP for neonatal respiratory distress syndrome in a low-resource setting.

Carns J, Kawaza K, Quinn MK, Miao Y, Guerra R, Molyneux E, Oden M, Richards-Kortum R.

PLoS One. 2018 Mar 15;13(3):e0194144. doi: 10.1371/journal.pone.0194144. eCollection 2018.


Development of a universal, tunable, miniature fluorescence microscope for use at the point of care.

Wong C, Pawlowski ME, Forcucci A, Majors CE, Richards-Kortum R, Tkaczyk TS.

Biomed Opt Express. 2018 Feb 7;9(3):1041-1056. doi: 10.1364/BOE.9.001041. eCollection 2018 Mar 1.


Paper-based detection of HIV-1 drug resistance using isothermal amplification and an oligonucleotide ligation assay.

Natoli ME, Rohrman BA, De Santiago C, van Zyl GU, Richards-Kortum RR.

Anal Biochem. 2018 Mar 1;544:64-71. doi: 10.1016/j.ab.2017.12.008. Epub 2017 Dec 8.


Point-of-care device to diagnose and monitor neonatal jaundice in low-resource settings.

Keahey PA, Simeral ML, Schroder KJ, Bond MM, Mtenthaonnga PJ, Miros RH, Dube Q, Richards-Kortum RR.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10965-E10971. doi: 10.1073/pnas.1714020114. Epub 2017 Dec 4.


Position paper: The potential role of optical biopsy in the study and diagnosis of environmental enteric dysfunction.

Thompson AJ, Hughes M, Anastasova S, Conklin LS, Thomas T, Leggett C, Faubion WA, Miller TJ, Delaney P, Lacombe F, Loiseau S, Meining A, Richards-Kortum R, Tearney GJ, Kelly P, Yang GZ.

Nat Rev Gastroenterol Hepatol. 2017 Dec;14(12):727-738. doi: 10.1038/nrgastro.2017.147. Epub 2017 Nov 15. Review.


Tools To Reduce Newborn Deaths In Africa.

Richards-Kortum RR.

Health Aff (Millwood). 2017 Nov;36(11):2019-2022. doi: 10.1377/hlthaff.2017.1141.


Line-scanning confocal microendoscope for nuclear morphometry imaging.

Tang Y, Carns J, Richards-Kortum RR.

J Biomed Opt. 2017 Nov;22(11):1-6. doi: 10.1117/1.JBO.22.11.116005.


Towards a needle-free diagnosis of malaria: in vivo identification and classification of red and white blood cells containing haemozoin.

Burnett JL, Carns JL, Richards-Kortum R.

Malar J. 2017 Nov 7;16(1):447. doi: 10.1186/s12936-017-2096-1.


Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings.

Majors CE, Smith CA, Natoli ME, Kundrod KA, Richards-Kortum R.

Lab Chip. 2017 Oct 11;17(20):3351-3387. doi: 10.1039/c7lc00374a. Review.


Prospective Evaluation of Multimodal Optical Imaging with Automated Image Analysis to Detect Oral Neoplasia In Vivo.

Quang T, Tran EQ, Schwarz RA, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum R.

Cancer Prev Res (Phila). 2017 Oct;10(10):563-570. doi: 10.1158/1940-6207.CAPR-17-0054. Epub 2017 Aug 1.


Development of a multimodal foveated endomicroscope for the detection of oral cancer.

Shadfan A, Darwiche H, Blanco J, Gillenwater A, Richards-Kortum R, Tkaczyk TS.

Biomed Opt Express. 2017 Feb 14;8(3):1525-1535. doi: 10.1364/BOE.8.001525. eCollection 2017 Mar 1.


Evaluation of a low-cost, low-power syringe pump to deliver magnesium sulfate intravenously to pre-eclamptic women in a Malawian referral hospital.

Skerrett E, Kommwa E, Maynard K, Juarez A, Mataya R, Richards-Kortum R, Oden ZM.

BMC Pregnancy Childbirth. 2017 Jun 19;17(1):191. doi: 10.1186/s12884-017-1382-9.


Towards a point-of-care strip test to diagnose sickle cell anemia.

Bond M, Hunt B, Flynn B, Huhtinen P, Ware R, Richards-Kortum R.

PLoS One. 2017 May 16;12(5):e0177732. doi: 10.1371/journal.pone.0177732. eCollection 2017.


Efficacy of a low-cost bubble CPAP system in treatment of respiratory distress in a neonatal ward in Malawi.

Kawaza K, Machen HE, Brown J, Mwanza Z, Iniguez S, Gest A, O'Brian Smith E, Oden M, Richards-Kortum RR, Molyneux E.

Malawi Med J. 2016 Sep;28(3):131-137.


A paper-based immunoassay to determine HPV vaccination status at the point-of-care.

Grant BD, Smith CA, Castle PE, Scheurer ME, Richards-Kortum R.

Vaccine. 2016 Nov 4;34(46):5656-5663. doi: 10.1016/j.vaccine.2016.09.021. Epub 2016 Sep 22.


Differential structured illumination microendoscopy for in vivo imaging of molecular contrast agents.

Keahey P, Ramalingam P, Schmeler K, Richards-Kortum RR.

Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10769-73. doi: 10.1073/pnas.1613497113. Epub 2016 Sep 12.


In vivo white light and contrast-enhanced vital-dye fluorescence imaging of Barrett's-related neoplasia in a single-endoscopic insertion.

Tang Y, Carns J, Polydorides AD, Anandasabapathy S, Richards-Kortum RR.

J Biomed Opt. 2016 Aug 1;21(8):86004. doi: 10.1117/1.JBO.21.8.086004.


In vivo cytological observation of liver and spleen by using high-resolution microendoscopy system under endoscopic ultrasound guidance: A preliminary study using a swine model.

Suzuki R, Shin D, Richards-Kortum R, Coghlan L, Bhutani MS.

Endosc Ultrasound. 2016 Jul-Aug;5(4):239-42. doi: 10.4103/2303-9027.187867.


Diagnosing Postpartum Hemorrhage: A New Way to Assess Blood Loss in a Low-Resource Setting.

Wilcox L, Ramprasad C, Gutierrez A, Oden M, Richards-Kortum R, Sangi-Haghpeykar H, Gandhi M.

Matern Child Health J. 2017 Mar;21(3):516-523. doi: 10.1007/s10995-016-2135-5.


AutoSyP: A Low-Cost, Low-Power Syringe Pump for Use in Low-Resource Settings.

Juarez A, Maynard K, Skerrett E, Molyneux E, Richards-Kortum R, Dube Q, Oden ZM.

Am J Trop Med Hyg. 2016 Oct 5;95(4):964-969. doi: 10.4269/ajtmh.16-0285. Epub 2016 Jul 5.


Confocal fluorescence microscopy to evaluate changes in adipocytes in the tumor microenvironment associated with invasive ductal carcinoma and ductal carcinoma in situ.

Dobbs JL, Shin D, Krishnamurthy S, Kuerer H, Yang W, Richards-Kortum R.

Int J Cancer. 2016 Sep 1;139(5):1140-9. doi: 10.1002/ijc.30160. Epub 2016 May 14.


A tablet-interfaced high-resolution microendoscope with automated image interpretation for real-time evaluation of esophageal squamous cell neoplasia.

Quang T, Schwarz RA, Dawsey SM, Tan MC, Patel K, Yu X, Wang G, Zhang F, Xu H, Anandasabapathy S, Richards-Kortum R.

Gastrointest Endosc. 2016 Nov;84(5):834-841. doi: 10.1016/j.gie.2016.03.1472. Epub 2016 Mar 30.


Highly Sensitive Two-Dimensional Paper Network Incorporating Biotin-Streptavidin for the Detection of Malaria.

Grant BD, Smith CA, Karvonen K, Richards-Kortum R.

Anal Chem. 2016 Mar 1;88(5):2553-7. doi: 10.1021/acs.analchem.5b03999. Epub 2016 Feb 16.


Multiplexed Recombinase Polymerase Amplification Assay To Detect Intestinal Protozoa.

Crannell Z, Castellanos-Gonzalez A, Nair G, Mejia R, White AC, Richards-Kortum R.

Anal Chem. 2016 Feb 2;88(3):1610-6. doi: 10.1021/acs.analchem.5b03267. Epub 2016 Jan 12.


High-resolution microendoscopy: a point-of-care diagnostic for cervical dysplasia in low-resource settings.

Grant BD, Fregnani JH, Possati Resende JC, Scapulatempo-Neto C, Matsushita GM, Mauad EC, Quang T, Stoler MH, Castle PE, Schmeler KM, Richards-Kortum RR.

Eur J Cancer Prev. 2017 Jan;26(1):63-70.


A paper and plastic device for the combined isothermal amplification and lateral flow detection of Plasmodium DNA.

Cordray MS, Richards-Kortum RR.

Malar J. 2015 Nov 26;14:472. doi: 10.1186/s12936-015-0995-6.


All-plastic, miniature, digital fluorescence microscope for three part white blood cell differential measurements at the point of care.

Forcucci A, Pawlowski ME, Majors C, Richards-Kortum R, Tkaczyk TS.

Biomed Opt Express. 2015 Oct 19;6(11):4433-46. doi: 10.1364/BOE.6.004433. eCollection 2015 Nov 1.


Drop-to-drop variation in the cellular components of fingerprick blood: implications for point-of-care diagnostic development.

Bond MM, Richards-Kortum RR.

Am J Clin Pathol. 2015 Dec;144(6):885-94. doi: 10.1309/AJCP1L7DKMPCHPEH.


All-plastic miniature fluorescence microscope for point-of-care readout of bead-based bioassays.

Forcucci A, Pawlowski ME, Crannell Z, Pavlova I, Richards-Kortum R, Tkaczyk TS.

J Biomed Opt. 2015 Oct;20(10):105010. doi: 10.1117/1.JBO.20.10.105010.


Design of a New Type of Compact Chemical Heater for Isothermal Nucleic Acid Amplification.

Shah KG, Guelig D, Diesburg S, Buser J, Burton R, LaBarre P, Richards-Kortum R, Weigl B.

PLoS One. 2015 Oct 2;10(10):e0139449. doi: 10.1371/journal.pone.0139449. eCollection 2015.


In vivo microscopy of hemozoin: towards a needle free diagnostic for malaria.

Burnett JL, Carns JL, Richards-Kortum R.

Biomed Opt Express. 2015 Aug 21;6(9):3462-74. doi: 10.1364/BOE.6.003462. eCollection 2015 Sep 1.


Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer.

Jain S, Wang X, Chang CC, Ibarra-Drendall C, Wang H, Zhang Q, Brady SW, Li P, Zhao H, Dobbs J, Kyrish M, Tkaczyk TS, Ambrose A, Sistrunk C, Arun BK, Richards-Kortum R, Jia W, Seewaldt VL, Yu D.

Cancer Res. 2015 Nov 15;75(22):4863-75. doi: 10.1158/0008-5472.CAN-14-2345. Epub 2015 Sep 17.


High-resolution microendoscopy in differentiating neoplastic from non-neoplastic colorectal polyps.

Louie JS, Shukla R, Richards-Kortum R, Anandasabapathy S.

Best Pract Res Clin Gastroenterol. 2015 Aug;29(4):663-73. doi: 10.1016/j.bpg.2015.05.011. Epub 2015 Jun 4. Review.


Outcomes of Patients with Respiratory Distress Treated with Bubble CPAP on a Pediatric Ward in Malawi.

Machen HE, Mwanza ZV, Brown JK, Kawaza KM, Newberry L, Richards-Kortum RR, Oden ZM, Molyneux EM.

J Trop Pediatr. 2015 Dec;61(6):421-7. doi: 10.1093/tropej/fmv052. Epub 2015 Sep 11.


Micro-anatomical quantitative optical imaging: toward automated assessment of breast tissues.

Dobbs JL, Mueller JL, Krishnamurthy S, Shin D, Kuerer H, Yang W, Ramanujam N, Richards-Kortum R.

Breast Cancer Res. 2015 Aug 20;17:105. doi: 10.1186/s13058-015-0617-9.


Quantitative analysis of high-resolution microendoscopic images for diagnosis of neoplasia in patients with Barrett's esophagus.

Shin D, Lee MH, Polydorides AD, Pierce MC, Vila PM, Parikh ND, Rosen DG, Anandasabapathy S, Richards-Kortum RR.

Gastrointest Endosc. 2016 Jan;83(1):107-14. doi: 10.1016/j.gie.2015.06.045. Epub 2015 Aug 5.


High-resolution microendoscope imaging of inverted papilloma and normal sinonasal mucosa: evaluation of interobserver concordance.

Parasher AK, Kidwai SM, Schorn VJ, Goljo E, Weinberg AD, Richards-Kortum R, Sikora AG, Iloreta AM, Govindaraj S, Miles BA.

Int Forum Allergy Rhinol. 2015 Dec;5(12):1136-40. doi: 10.1002/alr.21603. Epub 2015 Jul 30.


Confocal foveated endomicroscope for the detection of esophageal carcinoma.

Shadfan A, Hellebust A, Richards-Kortum R, Tkaczyk T.

Biomed Opt Express. 2015 Jun 3;6(7):2311-24. doi: 10.1364/BOE.6.002311. eCollection 2015 Jul 1.


Detection of Entamoeba histolytica by Recombinase Polymerase Amplification.

Nair G, Rebolledo M, White AC Jr, Crannell Z, Richards-Kortum RR, Pinilla AE, Ramírez JD, López MC, Castellanos-Gonzalez A.

Am J Trop Med Hyg. 2015 Sep;93(3):591-5. doi: 10.4269/ajtmh.15-0276. Epub 2015 Jun 29.


Operative margin control with high-resolution optical microendoscopy for head and neck squamous cell carcinoma.

Miles BA, Patsias A, Quang T, Polydorides AD, Richards-Kortum R, Sikora AG.

Laryngoscope. 2015 Oct;125(10):2308-16. doi: 10.1002/lary.25400. Epub 2015 Jun 9.


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