Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 182


Extracellular Matrix and Fibrocyte Accumulation in BALB/c Mouse Lung upon Transient Overexpression of Oncostatin M.

Botelho FM, Rodrigues R, Guerette J, Wong S, Fritz DK, Richards CD.

Cells. 2019 Feb 5;8(2). pii: E126. doi: 10.3390/cells8020126.


IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages.

Ayaub EA, Tandon K, Padwal M, Imani J, Patel H, Dubey A, Mekhael O, Upagupta C, Ayoub A, Dvorkin-Gheva A, Murphy J, Kolb PS, Lhotak S, Dickhout JG, Austin RC, Kolb MRJ, Richards CD, Ask K.

Immunol Cell Biol. 2019 Feb;97(2):203-217. doi: 10.1111/imcb.12212. Epub 2018 Nov 14.


IL-15 and IFN-γ signal through the ERK pathway to inhibit HCV replication, independent of type I IFN signaling.

Vahedi F, Lee AJ, Collins SE, Chew MV, Lusty E, Chen B, Dubey A, Richards CD, Feld JJ, Russell RS, Mossman KL, Ashkar AA.

Cytokine. 2018 Jun 13. pii: S1043-4666(18)30254-0. doi: 10.1016/j.cyto.2018.06.006. [Epub ahead of print]


Separate roles of IL-6 and oncostatin M in mouse macrophage polarization in vitro and in vivo.

Dubey A, Izakelian L, Ayaub EA, Ho L, Stephenson K, Wong S, Kwofie K, Austin RC, Botelho F, Ask K, Richards CD.

Immunol Cell Biol. 2018 Mar;96(3):257-272. doi: 10.1111/imcb.1035. Epub 2017 Dec 26.


Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis.

Ayaub EA, Dubey A, Imani J, Botelho F, Kolb MRJ, Richards CD, Ask K.

Sci Rep. 2017 Oct 16;7(1):13281. doi: 10.1038/s41598-017-13511-z.


A role for the Drosophila zinc transporter Zip88E in protecting against dietary zinc toxicity.

Richards CD, Warr CG, Burke R.

PLoS One. 2017 Jul 13;12(7):e0181237. doi: 10.1371/journal.pone.0181237. eCollection 2017.


IL-18/IL-15/IL-12 synergy induces elevated and prolonged IFN-γ production by ex vivo expanded NK cells which is not due to enhanced STAT4 activation.

Lusty E, Poznanski SM, Kwofie K, Mandur TS, Lee DA, Richards CD, Ashkar AA.

Mol Immunol. 2017 Aug;88:138-147. doi: 10.1016/j.molimm.2017.06.025. Epub 2017 Jun 20.


Innate Immune Cytokines, Fibroblast Phenotypes, and Regulation of Extracellular Matrix in Lung.

Richards CD.

J Interferon Cytokine Res. 2017 Feb;37(2):52-61. doi: 10.1089/jir.2016.0112. Epub 2017 Jan 24. Review.


Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells.

Richards CD, Izakelian L, Dubey A, Zhang G, Wong S, Kwofie K, Qureshi A, Botelho F.

Mediators Inflamm. 2016;2016:9858374. Epub 2016 Sep 15.


Characterization of Proliferating Lesion-Resident Cells During All Stages of Atherosclerotic Growth.

Lhoták Š, Gyulay G, Cutz JC, Al-Hashimi A, Trigatti BL, Richards CD, Igdoura SA, Steinberg GR, Bramson J, Ask K, Austin RC.

J Am Heart Assoc. 2016 Aug 15;5(8). pii: e003945. doi: 10.1161/JAHA.116.003945.


A fly's eye view of zinc homeostasis: Novel insights into the genetic control of zinc metabolism from Drosophila.

Richards CD, Burke R.

Arch Biochem Biophys. 2016 Dec 1;611:142-149. doi: 10.1016/ Epub 2016 Jul 22. Review.


Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation.

Pohin M, Guesdon W, Mekouo AA, Rabeony H, Paris I, Atanassov H, Favot L, Mcheik J, Bernard FX, Richards CD, Amiaud J, Blanchard F, Lecron JC, Morel F, Jégou JF.

Eur J Immunol. 2016 Jul;46(7):1737-51. doi: 10.1002/eji.201546216. Epub 2016 May 12.


A role for dZIP89B in Drosophila dietary zinc uptake reveals additional complexity in the zinc absorption process.

Richards CD, Warr CG, Burke R.

Int J Biochem Cell Biol. 2015 Dec;69:11-9. doi: 10.1016/j.biocel.2015.10.004. Epub 2015 Oct 13.


Local and systemic effects of targeted zinc redistribution in Drosophila neuronal and gastrointestinal tissues.

Richards CD, Burke R.

Biometals. 2015 Dec;28(6):967-74. doi: 10.1007/s10534-015-9881-5. Epub 2015 Sep 28.


Oncostatin M induces IL-33 expression in liver endothelial cells in mice and expands ST2+CD4+ lymphocytes.

Arshad MI, Guihard P, Danger Y, Noel G, Le Seyec J, Boutet MA, Richards CD, L'Helgoualc'h A, Genet V, Lucas-Clerc C, Gascan H, Blanchard F, Piquet-Pellorce C, Samson M.

Am J Physiol Gastrointest Liver Physiol. 2015 Oct 1;309(7):G542-53. doi: 10.1152/ajpgi.00398.2014. Epub 2015 Aug 6.


Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M.

Kwofie K, Scott M, Rodrigues R, Guerette J, Radford K, Nair P, Richards CD.

Respir Res. 2015 Feb 7;16:14. doi: 10.1186/s12931-014-0164-4.


Oncostatin M regulates osteogenic differentiation of murine adipose-derived mesenchymal progenitor cells through a PKCdelta-dependent mechanism.

Smyth DC, Takenaka S, Yeung C, Richards CD.

Cell Tissue Res. 2015 May;360(2):309-19. doi: 10.1007/s00441-014-2099-y. Epub 2015 Jan 30.


Compartmentalized zinc deficiency and toxicities caused by ZnT and Zip gene over expression result in specific phenotypes in Drosophila.

Dechen K, Richards CD, Lye JC, Hwang JE, Burke R.

Int J Biochem Cell Biol. 2015 Mar;60:23-33. doi: 10.1016/j.biocel.2014.12.017. Epub 2015 Jan 3.


Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity.

Barra NG, Palanivel R, Denou E, Chew MV, Gillgrass A, Walker TD, Kong J, Richards CD, Jordana M, Collins SM, Trigatti BL, Holloway AC, Raha S, Steinberg GR, Ashkar AA.

PLoS One. 2014 Dec 17;9(12):e114799. doi: 10.1371/journal.pone.0114799. eCollection 2014.


Novel function of Oncostatin M as a potent tumour-promoting agent in lung.

Lauber S, Wong S, Cutz JC, Tanaka M, Barra N, Lhoták S, Ashkar A, Richards CD.

Int J Cancer. 2015 Feb 15;136(4):831-43. doi: 10.1002/ijc.29055. Epub 2014 Jul 7.


Oncostatin M overexpression induces matrix deposition, STAT3 activation, and SMAD1 Dysregulation in lungs of fibrosis-resistant BALB/c mice.

Wong S, Botelho FM, Rodrigues RM, Richards CD.

Lab Invest. 2014 Sep;94(9):1003-16. doi: 10.1038/labinvest.2014.81. Epub 2014 Jun 16.


The enigmatic cytokine oncostatin m and roles in disease.

Richards CD.

ISRN Inflamm. 2013 Dec 8;2013:512103. doi: 10.1155/2013/512103. Review.


Oncostatin M and TLR-4 ligand synergize to induce MCP-1, IL-6, and VEGF in human aortic adventitial fibroblasts and smooth muscle cells.

Schnittker D, Kwofie K, Ashkar A, Trigatti B, Richards CD.

Mediators Inflamm. 2013;2013:317503. doi: 10.1155/2013/317503. Epub 2013 Nov 6.


Pulmonary expression of oncostatin M (OSM) promotes inducible BALT formation independently of IL-6, despite a role for IL-6 in OSM-driven pulmonary inflammation.

Botelho FM, Rangel-Moreno J, Fritz D, Randall TD, Xing Z, Richards CD.

J Immunol. 2013 Aug 1;191(3):1453-64. doi: 10.4049/jimmunol.1203318. Epub 2013 Jun 24.


In vivo zinc toxicity phenotypes provide a sensitized background that suggests zinc transport activities for most of the Drosophila Zip and ZnT genes.

Lye JC, Richards CD, Dechen K, Warr CG, Burke R.

J Biol Inorg Chem. 2013 Mar;18(3):323-32. doi: 10.1007/s00775-013-0976-6. Epub 2013 Jan 17.


Small-conductance Ca2+-activated K+ channels modulate action potential-induced Ca2+ transients in hippocampal neurons.

Tonini R, Ferraro T, Sampedro-Castañeda M, Cavaccini A, Stocker M, Richards CD, Pedarzani P.

J Neurophysiol. 2013 Mar;109(6):1514-24. doi: 10.1152/jn.00346.2012. Epub 2012 Dec 19.


Systematic functional characterization of putative zinc transport genes and identification of zinc toxicosis phenotypes in Drosophila melanogaster.

Lye JC, Richards CD, Dechen K, Paterson D, de Jonge MD, Howard DL, Warr CG, Burke R.

J Exp Biol. 2012 Sep 15;215(Pt 18):3254-65. doi: 10.1242/jeb.069260. Epub 2012 Jun 12.


Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis.

O'Donoghue RJ, Knight DA, Richards CD, Prêle CM, Lau HL, Jarnicki AG, Jones J, Bozinovski S, Vlahos R, Thiem S, McKenzie BS, Wang B, Stumbles P, Laurent GJ, McAnulty RJ, Rose-John S, Zhu HJ, Anderson GP, Ernst MR, Mutsaers SE.

EMBO Mol Med. 2012 Sep;4(9):939-51. doi: 10.1002/emmm.201100604. Epub 2012 Jun 8.


IL-15 can signal via IL-15Rα, JNK, and NF-κB to drive RANTES production by myeloid cells.

Chenoweth MJ, Mian MF, Barra NG, Alain T, Sonenberg N, Bramson J, Lichty BD, Richards CD, Ma A, Ashkar AA.

J Immunol. 2012 May 1;188(9):4149-57. doi: 10.4049/jimmunol.1101883. Epub 2012 Mar 23.


Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling.

Guihard P, Danger Y, Brounais B, David E, Brion R, Delecrin J, Richards CD, Chevalier S, Rédini F, Heymann D, Gascan H, Blanchard F.

Stem Cells. 2012 Apr;30(4):762-72. doi: 10.1002/stem.1040.


Direct anti-cancer effect of oncostatin M on chondrosarcoma.

David E, Guihard P, Brounais B, Riet A, Charrier C, Battaglia S, Gouin F, Ponsolle S, Bot RL, Richards CD, Heymann D, Rédini F, Blanchard F.

Int J Cancer. 2011 Apr 15;128(8):1822-35. doi: 10.1002/ijc.25776. Epub 2011 Jan 6.


A mouse model of airway disease: oncostatin M-induced pulmonary eosinophilia, goblet cell hyperplasia, and airway hyperresponsiveness are STAT6 dependent, and interstitial pulmonary fibrosis is STAT6 independent.

Fritz DK, Kerr C, Fattouh R, Llop-Guevara A, Khan WI, Jordana M, Richards CD.

J Immunol. 2011 Jan 15;186(2):1107-18. doi: 10.4049/jimmunol.0903476. Epub 2010 Dec 15.


Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: regulation of the type-II IL-4 receptor chains IL-4Ralpha and IL-13Ralpha1.

Fritz DK, Kerr C, Botelho F, Stampfli M, Richards CD.

Exp Cell Res. 2009 Dec 10;315(20):3486-99. doi: 10.1016/j.yexcr.2009.09.024. Epub 2009 Sep 30.


Thermocompression bonding of vertically aligned carbon nanotube turfs to metalized substrates.

Johnson RD, Bahr DF, Richards CD, Richards RF, McClain D, Green J, Jiao J.

Nanotechnology. 2009 Feb 11;20(6):065703. doi: 10.1088/0957-4484/20/6/065703. Epub 2009 Jan 15.


Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study.

Hirota JA, Ask K, Fritz D, Ellis R, Wattie J, Richards CD, Labiris R, Kolb M, Inman MD.

Clin Exp Allergy. 2009 Jan;39(1):147-58. doi: 10.1111/j.1365-2222.2008.03109.x. Epub 2008 Oct 11.


Oncostatin M induces bone loss and sensitizes rat osteosarcoma to the antitumor effect of Midostaurin in vivo.

Brounais B, Chipoy C, Mori K, Charrier C, Battaglia S, Pilet P, Richards CD, Heymann D, Rédini F, Blanchard F.

Clin Cancer Res. 2008 Sep 1;14(17):5400-9. doi: 10.1158/1078-0432.CCR-07-4781.


Measurement of interleukin 6.

Nordan RP, Richards CD, Gauldie J.

Curr Protoc Immunol. 2001 May;Chapter 6:Unit 6.6. doi: 10.1002/0471142735.im0606s17.


A facility for characterizing the steady-state and dynamic thermal performance of microelectromechanical system thermal switches.

Cho JH, Richards CD, Richards RF.

Rev Sci Instrum. 2008 Mar;79(3):034901. doi: 10.1063/1.2894147.


Oncostatin M induction of eotaxin-1 expression requires the convergence of PI3'K and ERK1/2 MAPK signal transduction pathways.

Smyth DC, Kerr C, Li Y, Tang D, Richards CD.

Cell Signal. 2008 Jun;20(6):1142-50. doi: 10.1016/j.cellsig.2008.02.001. Epub 2008 Feb 11.


Prostaglandin E2 sensitizes primary sensory neurons to histamine.

Nicolson TA, Foster AF, Bevan S, Richards CD.

Neuroscience. 2007 Nov 30;150(1):22-30. Epub 2007 Sep 14.


Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: implications for cartilage degradation in arthritis.

Barksby HE, Milner JM, Patterson AM, Peake NJ, Hui W, Robson T, Lakey R, Middleton J, Cawston TE, Richards CD, Rowan AD.

Arthritis Rheum. 2006 Oct;54(10):3244-53.


Oncostatin-M up-regulates VCAM-1 and synergizes with IL-4 in eotaxin expression: involvement of STAT6.

Fritz DK, Kerr C, Tong L, Smyth D, Richards CD.

J Immunol. 2006 Apr 1;176(7):4352-60.


Interleukin-1 in combination with oncostatin M up-regulates multiple genes in chondrocytes: implications for cartilage destruction and repair.

Barksby HE, Hui W, Wappler I, Peters HH, Milner JM, Richards CD, Cawston TE, Rowan AD.

Arthritis Rheum. 2006 Feb;54(2):540-50.


A MEMS fabricated flexible electrode array for recording surface field potentials.

Hollenberg BA, Richards CD, Richards R, Bahr DF, Rector DM.

J Neurosci Methods. 2006 May 15;153(1):147-53. Epub 2005 Dec 13.


Mainstream cigarette smoke exposure attenuates airway immune inflammatory responses to surrogate and common environmental allergens in mice, despite evidence of increased systemic sensitization.

Robbins CS, Pouladi MA, Fattouh R, Dawe DE, Vujicic N, Richards CD, Jordana M, Inman MD, Stampfli MR.

J Immunol. 2005 Sep 1;175(5):2834-42.


Fast vesicle replenishment allows indefatigable signalling at the first auditory synapse.

Griesinger CB, Richards CD, Ashmore JF.

Nature. 2005 May 12;435(7039):212-5. Epub 2005 Apr 13.


Matrix catabolism in arthritis: priming the guns with oncostatin M.

Richards CD.

J Rheumatol. 2004 Dec;31(12):2326-8. No abstract available.


Apical endocytosis in outer hair cells of the mammalian cochlea.

Griesinger CB, Richards CD, Ashmore JF.

Eur J Neurosci. 2004 Jul;20(1):41-50.


Supplemental Content

Loading ...
Support Center