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Items: 36

1.

L-Pgds but not H-Pgds deletion causes hypertension and accelerates thrombogenesis in mice.

Song WL, Ricciotti E, Liang X, Grosser T, Grant GR, FitzGerald GA.

J Pharmacol Exp Ther. 2018 Oct 10. pii: jpet.118.250936. doi: 10.1124/jpet.118.250936. [Epub ahead of print]

2.

Cyclooxygenase-2, Asymmetric Dimethylarginine and the Cardiovascular Hazard from NSAIDs.

Ricciotti E, Castro C, Tang SY, Briggs WTE, West JA, Malik D, Rhoades SD, Meng H, Li X, Lahens NF, Sparks JA, Karlson EW, Weljie AM, Griffin JL, FitzGerald GA.

Circulation. 2018 Jun 21. pii: CIRCULATIONAHA.118.033540. doi: 10.1161/CIRCULATIONAHA.118.033540. [Epub ahead of print]

PMID:
29930022
3.

COX-2 mediates pro-tumorigenic effects of PKCε in prostate cancer.

Garg R, Blando JM, Perez CJ, Lal P, Feldman MD, Smyth EM, Ricciotti E, Grosser T, Benavides F, Kazanietz MG.

Oncogene. 2018 May 16. doi: 10.1038/s41388-018-0318-9. [Epub ahead of print]

PMID:
29765153
4.

A comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expression.

Lahens NF, Ricciotti E, Smirnova O, Toorens E, Kim EJ, Baruzzo G, Hayer KE, Ganguly T, Schug J, Grant GR.

BMC Genomics. 2017 Aug 10;18(1):602. doi: 10.1186/s12864-017-4011-0.

5.

The Cardiovascular Pharmacology of Nonsteroidal Anti-Inflammatory Drugs.

Grosser T, Ricciotti E, FitzGerald GA.

Trends Pharmacol Sci. 2017 Aug;38(8):733-748. doi: 10.1016/j.tips.2017.05.008. Epub 2017 Jun 23. Review.

6.

Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity.

Lin W, Vann DR, Doulias PT, Wang T, Landesberg G, Li X, Ricciotti E, Scalia R, He M, Hand NJ, Rader DJ.

J Clin Invest. 2017 Jun 1;127(6):2407-2417. doi: 10.1172/JCI90896. Epub 2017 May 8.

7.

A broad-spectrum lipidomics screen of antiinflammatory drug combinations in human blood.

Mazaleuskaya LL, Lawson JA, Li X, Grant G, Mesaros C, Grosser T, Blair IA, Ricciotti E, FitzGerald GA.

JCI Insight. 2016 Aug 4;1(12). pii: e87031.

8.

Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells.

Guillem-Llobat P, Dovizio M, Bruno A, Ricciotti E, Cufino V, Sacco A, Grande R, Alberti S, Arena V, Cirillo M, Patrono C, FitzGerald GA, Steinhilber D, Sgambato A, Patrignani P.

Oncotarget. 2016 May 31;7(22):32462-77. doi: 10.18632/oncotarget.8655.

9.

Understanding multicellular function and disease with human tissue-specific networks.

Greene CS, Krishnan A, Wong AK, Ricciotti E, Zelaya RA, Himmelstein DS, Zhang R, Hartmann BM, Zaslavsky E, Sealfon SC, Chasman DI, FitzGerald GA, Dolinski K, Grosser T, Troyanskaya OG.

Nat Genet. 2015 Jun;47(6):569-76. doi: 10.1038/ng.3259. Epub 2015 Apr 27.

10.

COX-2, the dominant source of prostacyclin.

Ricciotti E, Yu Y, Grosser T, Fitzgerald GA.

Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):E183. doi: 10.1073/pnas.1219073110. Epub 2013 Jan 4. No abstract available.

11.

Myeloid cell 5-lipoxygenase activating protein modulates the response to vascular injury.

Yu Z, Ricciotti E, Miwa T, Liu S, Ihida-Stansbury K, Landesberg G, Jones PL, Scalia R, Song WC, Assoian RK, FitzGerald GA.

Circ Res. 2013 Feb 1;112(3):432-40. doi: 10.1161/CIRCRESAHA.112.300755. Epub 2012 Dec 18. Erratum in: Circ Res. 2016 Jul 22;119(3):e37.

12.

Functionalized low-density lipoprotein nanoparticles for in vivo enhancement of atherosclerosis on magnetic resonance images.

Lowell AN, Qiao H, Liu T, Ishikawa T, Zhang H, Oriana S, Wang M, Ricciotti E, FitzGerald GA, Zhou R, Yamakoshi Y.

Bioconjug Chem. 2012 Nov 21;23(11):2313-9. doi: 10.1021/bc300561e. Epub 2012 Nov 1.

PMID:
23075169
13.

Novel aminobenzyl-acetamidine derivative modulate the differential regulation of NOSs in LPS induced inflammatory response: role of PI3K/Akt pathway.

Patruno A, Franceschelli S, Pesce M, Maccallini C, Fantacuzzi M, Speranza L, Ferrone A, De Lutiis MA, Ricciotti E, Amoroso R, Felaco M.

Biochim Biophys Acta. 2012 Dec;1820(12):2095-104. doi: 10.1016/j.bbagen.2012.08.014. Epub 2012 Aug 23.

PMID:
22951221
14.

Vascular COX-2 modulates blood pressure and thrombosis in mice.

Yu Y, Ricciotti E, Scalia R, Tang SY, Grant G, Yu Z, Landesberg G, Crichton I, Wu W, Puré E, Funk CD, FitzGerald GA.

Sci Transl Med. 2012 May 2;4(132):132ra54. doi: 10.1126/scitranslmed.3003787.

15.

Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice.

Yu Z, Crichton I, Tang SY, Hui Y, Ricciotti E, Levin MD, Lawson JA, Puré E, FitzGerald GA.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6727-32. doi: 10.1073/pnas.1115313109. Epub 2012 Apr 9.

16.

Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.

Song WL, Stubbe J, Ricciotti E, Alamuddin N, Ibrahim S, Crichton I, Prempeh M, Lawson JA, Wilensky RL, Rasmussen LM, Puré E, FitzGerald GA.

J Clin Invest. 2012 Apr;122(4):1459-68. doi: 10.1172/JCI59262. Epub 2012 Mar 12.

17.

Effects of celecoxib on prostanoid biosynthesis and circulating angiogenesis proteins in familial adenomatous polyposis.

Dovizio M, Tacconelli S, Ricciotti E, Bruno A, Maier TJ, Anzellotti P, Di Francesco L, Sala P, Signoroni S, Bertario L, Dixon DA, Lawson JA, Steinhilber D, FitzGerald GA, Patrignani P.

J Pharmacol Exp Ther. 2012 Apr;341(1):242-50. doi: 10.1124/jpet.111.190785. Epub 2012 Jan 19.

18.

Mechanistic and pharmacological issues of aspirin as an anticancer agent.

Dovizio M, Tacconelli S, Sostres C, Ricciotti E, Patrignani P.

Pharmaceuticals (Basel). 2012 Dec 5;5(12):1346-71. doi: 10.3390/ph5121346.

19.

Prostaglandins and inflammation.

Ricciotti E, FitzGerald GA.

Arterioscler Thromb Vasc Biol. 2011 May;31(5):986-1000. doi: 10.1161/ATVBAHA.110.207449. Review.

20.

Targeted deletions of cyclooxygenase-2 and atherogenesis in mice.

Hui Y, Ricciotti E, Crichton I, Yu Z, Wang D, Stubbe J, Wang M, Puré E, FitzGerald GA.

Circulation. 2010 Jun 22;121(24):2654-60. doi: 10.1161/CIRCULATIONAHA.109.910687. Epub 2010 Jun 7.

21.

NCX 4040, a nitric oxide-donating aspirin, exerts anti-inflammatory effects through inhibition of I kappa B-alpha degradation in human monocytes.

Ricciotti E, Dovizio M, Di Francesco L, Anzellotti P, Salvatore T, Di Francesco A, Sciulli MG, Pistritto G, Monopoli A, Patrignani P.

J Immunol. 2010 Feb 15;184(4):2140-7. doi: 10.4049/jimmunol.0903107. Epub 2010 Jan 11.

22.

Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro.

Bruno A, Di Francesco L, Coletta I, Mangano G, Alisi MA, Polenzani L, Milanese C, Anzellotti P, Ricciotti E, Dovizio M, Di Francesco A, Tacconelli S, Capone ML, Patrignani P.

Biochem Pharmacol. 2010 Apr 1;79(7):974-81. doi: 10.1016/j.bcp.2009.11.011. Epub 2009 Nov 27.

PMID:
19925781
23.

The translational therapeutics of prostaglandin inhibition in atherothrombosis.

Yu Y, Ricciotti E, Grosser T, Fitzgerald GA.

J Thromb Haemost. 2009 Jul;7 Suppl 1:222-6. doi: 10.1111/j.1538-7836.2009.03439.x. Review.

24.

Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function.

Wang D, Patel VV, Ricciotti E, Zhou R, Levin MD, Gao E, Yu Z, Ferrari VA, Lu MM, Xu J, Zhang H, Hui Y, Cheng Y, Petrenko N, Yu Y, FitzGerald GA.

Proc Natl Acad Sci U S A. 2009 May 5;106(18):7548-52. doi: 10.1073/pnas.0805806106. Epub 2009 Apr 17.

25.

Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation.

Wang M, Lee E, Song W, Ricciotti E, Rader DJ, Lawson JA, Puré E, FitzGerald GA.

Circulation. 2008 Mar 11;117(10):1302-9. doi: 10.1161/CIRCULATIONAHA.107.731398. Epub 2008 Feb 19.

PMID:
18285567
26.

Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans.

Song WL, Wang M, Ricciotti E, Fries S, Yu Y, Grosser T, Reilly M, Lawson JA, FitzGerald GA.

J Biol Chem. 2008 Jan 11;283(2):1179-88. Epub 2007 Nov 8.

27.

Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis.

Wang M, Zukas AM, Hui Y, Ricciotti E, Puré E, FitzGerald GA.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14507-12. Epub 2006 Sep 14.

28.

Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease.

Sciulli MG, Renda G, Capone ML, Tacconelli S, Ricciotti E, Manarini S, Evangelista V, Rebuzzi A, Patrignani P.

Clin Pharmacol Ther. 2006 Aug;80(2):115-25. Epub 2006 Jul 3.

PMID:
16890573
29.

De novo synthesis of cyclooxygenase-1 counteracts the suppression of platelet thromboxane biosynthesis by aspirin.

Evangelista V, Manarini S, Di Santo A, Capone ML, Ricciotti E, Di Francesco L, Tacconelli S, Sacchetti A, D'Angelo S, Scilimati A, Sciulli MG, Patrignani P.

Circ Res. 2006 Mar 17;98(5):593-5. Epub 2006 Feb 16.

PMID:
16484611
30.

Reduced thromboxane biosynthesis in carriers of toll-like receptor 4 polymorphisms in vivo.

Patrignani P, Di Febbo C, Tacconelli S, Moretta V, Baccante G, Sciulli MG, Ricciotti E, Capone ML, Antonucci I, Guglielmi MD, Stuppia L, Porreca E.

Blood. 2006 May 1;107(9):3572-4. Epub 2006 Jan 5.

31.

Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects.

Capone ML, Sciulli MG, Tacconelli S, Grana M, Ricciotti E, Renda G, Di Gregorio P, Merciaro G, Patrignani P.

J Am Coll Cardiol. 2005 Apr 19;45(8):1295-301. Review.

32.

Platelet activation in patients with colorectal cancer.

Sciulli MG, Filabozzi P, Tacconelli S, Padovano R, Ricciotti E, Capone ML, Grana M, Carnevale V, Patrignani P.

Prostaglandins Leukot Essent Fatty Acids. 2005 Feb;72(2):79-83.

PMID:
15626589
33.

Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects.

Capone ML, Tacconelli S, Sciulli MG, Grana M, Ricciotti E, Minuz P, Di Gregorio P, Merciaro G, Patrono C, Patrignani P.

Circulation. 2004 Mar 30;109(12):1468-71. Epub 2004 Mar 22.

PMID:
15037526
34.

Effects of acetaminophen on constitutive and inducible prostanoid biosynthesis in human blood cells.

Sciulli MG, Seta F, Tacconelli S, Capone ML, Ricciotti E, Pistritto G, Patrignani P.

Br J Pharmacol. 2003 Feb;138(4):634-41.

35.

The biochemical selectivity of novel COX-2 inhibitors in whole blood assays of COX-isozyme activity.

Tacconelli S, Capone ML, Sciulli MG, Ricciotti E, Patrignani P.

Curr Med Res Opin. 2002;18(8):503-11.

PMID:
12564662
36.

The human pharmacology of monocyte cyclooxygenase 2 inhibition by cortisol and synthetic glucocorticoids.

Santini G, Patrignani P, Sciulli MG, Seta F, Tacconelli S, Panara MR, Ricciotti E, Capone ML, Patrono C.

Clin Pharmacol Ther. 2001 Nov;70(5):475-83.

PMID:
11719735

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