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Items: 1 to 50 of 89

1.

Mutation and structure guided discovery of an antiviral small molecule that mimics an essential C-Terminal tripeptide of the vaccinia D4 processivity factor.

Nuth M, Guan H, Xiao Y, Kulp JL 3rd, Parker MH, Strobel ED, Isaacs SN, Scott RW, Reitz AB, Ricciardi RP.

Antiviral Res. 2019 Feb;162:178-185. doi: 10.1016/j.antiviral.2018.12.011. Epub 2018 Dec 20.

PMID:
30578797
2.

A Conserved Tripeptide Sequence at the C Terminus of the Poxvirus DNA Processivity Factor D4 Is Essential for Protein Integrity and Function.

Nuth M, Guan H, Ricciardi RP.

J Biol Chem. 2016 Dec 30;291(53):27087-27097. doi: 10.1074/jbc.M116.761908. Epub 2016 Nov 11.

3.

Poxvirus uracil-DNA glycosylase-An unusual member of the family I uracil-DNA glycosylases.

Schormann N, Zhukovskaya N, Bedwell G, Nuth M, Gillilan R, Prevelige PE, Ricciardi RP, Banerjee S, Chattopadhyay D.

Protein Sci. 2016 Dec;25(12):2113-2131. doi: 10.1002/pro.3058. Epub 2016 Nov 2. Review.

4.

The processivity factor complex of feline herpes virus-1 is a new drug target.

Zhukovskaya NL, Guan H, Saw YL, Nuth M, Ricciardi RP.

Antiviral Res. 2015 Mar;115:17-20. doi: 10.1016/j.antiviral.2014.12.013. Epub 2014 Dec 24.

PMID:
25542973
5.

A novel target and approach for identifying antivirals against molluscum contagiosum virus.

Guan H, Nuth M, Zhukovskaya N, Saw YL, Bell E, Isaacs SN, Ricciardi RP.

Antimicrob Agents Chemother. 2014 Dec;58(12):7383-9. doi: 10.1128/AAC.03660-14. Epub 2014 Sep 29.

6.

Design of potent poxvirus inhibitors of the heterodimeric processivity factor required for viral replication.

Nuth M, Guan H, Zhukovskaya N, Saw YL, Ricciardi RP.

J Med Chem. 2013 Apr 25;56(8):3235-46. doi: 10.1021/jm301735k. Epub 2013 Apr 8.

PMID:
23527789
7.

Tumorigenic adenovirus 12 cells evade NK cell lysis by reducing the expression of NKG2D ligands.

Heyward CY, Patel R, Mace EM, Grier JT, Guan H, Makrigiannis AP, Orange JS, Ricciardi RP.

Immunol Lett. 2012 May 30;144(1-2):16-23. doi: 10.1016/j.imlet.2012.03.001. Epub 2012 Mar 14.

PMID:
22445355
8.

Transformation by E1A oncoprotein involves ubiquitin-mediated proteolysis of the neuronal and tumor repressor REST in the nucleus.

Guan H, Ricciardi RP.

J Virol. 2012 May;86(10):5594-602. doi: 10.1128/JVI.06811-11. Epub 2012 Mar 14.

9.

Identification of protein-protein interaction inhibitors targeting vaccinia virus processivity factor for development of antiviral agents.

Schormann N, Sommers CI, Prichard MN, Keith KA, Noah JW, Nuth M, Ricciardi RP, Chattopadhyay D.

Antimicrob Agents Chemother. 2011 Nov;55(11):5054-62. doi: 10.1128/AAC.00278-11. Epub 2011 Aug 15.

10.

Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4.

Nuth M, Huang L, Saw YL, Schormann N, Chattopadhyay D, Ricciardi RP.

J Med Chem. 2011 May 12;54(9):3260-7. doi: 10.1021/jm101554k. Epub 2011 Apr 19.

11.

Vaccinia virus D4 mutants defective in processive DNA synthesis retain binding to A20 and DNA.

Druck Shudofsky AM, Silverman JE, Chattopadhyay D, Ricciardi RP.

J Virol. 2010 Dec;84(23):12325-35. doi: 10.1128/JVI.01435-10. Epub 2010 Sep 22.

12.

Kaposi's sarcoma-associated herpesvirus processivity factor-8 dimerizes in cytoplasm before being translocated to nucleus.

Zhou X, Liao Q, Ricciardi RP, Peng C, Chen X.

Biochem Biophys Res Commun. 2010 Jul 2;397(3):520-5. doi: 10.1016/j.bbrc.2010.05.147. Epub 2010 May 31.

PMID:
20515658
13.
14.

The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus.

Baltz JL, Filman DJ, Ciustea M, Silverman JE, Lautenschlager CL, Coen DM, Ricciardi RP, Hogle JM.

J Virol. 2009 Dec;83(23):12215-28. doi: 10.1128/JVI.01158-09. Epub 2009 Sep 16.

15.

Induction of neuronal and tumor-related genes by adenovirus type 12 E1A.

Guan H, Williams JF, Ricciardi RP.

J Virol. 2009 Jan;83(2):651-61. doi: 10.1128/JVI.01538-08. Epub 2008 Nov 5.

16.

Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening.

Ciustea M, Silverman JE, Druck Shudofsky AM, Ricciardi RP.

J Med Chem. 2008 Oct 23;51(20):6563-70. doi: 10.1021/jm800366g. Epub 2008 Sep 23.

17.

Identification of polymerase and processivity inhibitors of vaccinia DNA synthesis using a stepwise screening approach.

Silverman JE, Ciustea M, Shudofsky AM, Bender F, Shoemaker RH, Ricciardi RP.

Antiviral Res. 2008 Nov;80(2):114-23. doi: 10.1016/j.antiviral.2008.05.010. Epub 2008 Jun 20.

18.
19.
20.

Chemical library screen for novel inhibitors of Kaposi's sarcoma-associated herpesvirus processive DNA synthesis.

Dorjsuren D, Burnette A, Gray GN, Chen X, Zhu W, Roberts PE, Currens MJ, Shoemaker RH, Ricciardi RP, Sei S.

Antiviral Res. 2006 Jan;69(1):9-23. Epub 2005 Nov 18.

PMID:
16337284
22.
23.

Rapid screening of chemical inhibitors that block processive DNA synthesis of herpesviruses: potential application to high-throughput screening.

Ricciardi RP, Lin K, Chen X, Dorjsuren D, Shoemaker R, Sei S.

Methods Mol Biol. 2005;292:481-92.

PMID:
15507726
24.

Human Kaposi's sarcoma herpesvirus processivity factor-8 functions as a dimer in DNA synthesis.

Chen X, Lin K, Ricciardi RP.

J Biol Chem. 2004 Jul 2;279(27):28375-86. Epub 2004 Apr 9.

25.

E1A-based determinants of oncogenicity in human adenovirus groups A and C.

Williams JF, Zhang Y, Williams MA, Hou S, Kushner D, Ricciardi RP.

Curr Top Microbiol Immunol. 2004;273:245-88. Review.

PMID:
14674604
26.

Phosphorylation of serine 337 of NF-kappaB p50 is critical for DNA binding.

Hou S, Guan H, Ricciardi RP.

J Biol Chem. 2003 Nov 14;278(46):45994-8. Epub 2003 Aug 28.

27.

Identification of genes associated with adenovirus 12 tumorigenesis by microarray.

Guan H, Smirnov DA, Ricciardi RP.

Virology. 2003 Apr 25;309(1):114-24.

30.

Coup-TFII is up-regulated in adenovirus type 12 tumorigenic cells and is a repressor of MHC class I transcription.

Smirnov DA, Hou S, Liu X, Claudio E, Siebenlist UK, Ricciardi RP.

Virology. 2001 May 25;284(1):13-9.

31.
32.

Oligomerization properties of the viral oncoproteins adenovirus E1A and human papillomavirus E7 and their complexes with the retinoblastoma protein.

Clements A, Johnston K, Mazzarelli JM, Ricciardi RP, Marmorstein R.

Biochemistry. 2000 Dec 26;39(51):16033-45.

PMID:
11123931
33.
35.

Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein.

Boyer TG, Martin ME, Lees E, Ricciardi RP, Berk AJ.

Nature. 1999 May 20;399(6733):276-9.

PMID:
10353252
39.

The transactivation domain of adenovirus E1A interacts with the C terminus of human TAF(II)135.

Mazzarelli JM, Mengus G, Davidson I, Ricciardi RP.

J Virol. 1997 Oct;71(10):7978-83.

40.

Human colorectal cancer (CRC) antigen CO17-1A/GA733 encoded by adenovirus inhibits growth of established CRC cells in mice.

Li W, Berencsi K, Basak S, Somasundaram R, Ricciardi RP, Gönczöl E, Zaloudik J, Linnenbach A, Maruyama H, Miniou P, Herlyn D.

J Immunol. 1997 Jul 15;159(2):763-9.

PMID:
9218593
41.
42.

Testing NF-kappa B1-p50 antibody specificity using knockout mice.

Pereira DS, Kushner DB, Ricciardi RP, Graham FL.

Oncogene. 1996 Jul 18;13(2):445-6.

PMID:
8710386
43.
45.

The viral oncoproteins Ad5 E1A, HPV16 E7 and SV40 TAg bind a common region of the TBP-associated factor-110.

Mazzarelli JM, Atkins GB, Geisberg JV, Ricciardi RP.

Oncogene. 1995 Nov 2;11(9):1859-64.

PMID:
7478615
46.
48.

Negative regulation by the R2 element of the MHC class I enhancer in adenovirus-12 transformed cells correlates with high levels of COUP-TF binding.

Liu X, Ge R, Westmoreland S, Cooney AJ, Tsai SY, Tsai MJ, Ricciardi RP.

Oncogene. 1994 Aug;9(8):2183-90.

PMID:
8036004
49.
50.

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