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Items: 1 to 50 of 86

1.

Upregulation of Epithelial-To-Mesenchymal Transition Markers and P2X7 Receptors Is Associated to Increased Invasiveness Caused by P2X7 Receptor Stimulation in Human Glioblastoma Stem Cells.

Ziberi S, Zuccarini M, Carluccio M, Giuliani P, Ricci-Vitiani L, Pallini R, Caciagli F, Di Iorio P, Ciccarelli R.

Cells. 2019 Dec 29;9(1). pii: E85. doi: 10.3390/cells9010085.

2.

Brain Invasion along Perivascular Spaces by Glioma Cells: Relationship with Blood-Brain Barrier.

Pacioni S, D'Alessandris QG, Buccarelli M, Boe A, Martini M, Larocca LM, Bolasco G, Ricci-Vitiani L, Falchetti ML, Pallini R.

Cancers (Basel). 2019 Dec 19;12(1). pii: E18. doi: 10.3390/cancers12010018.

3.

The Discovery of RNA Aptamers that Selectively Bind Glioblastoma Stem Cells.

Affinito A, Quintavalle C, Esposito CL, Roscigno G, Vilardo C, Nuzzo S, Ricci-Vitiani L, De Luca G, Pallini R, Kichkailo AS, Lapin IN, de Franciscis V, Condorelli G.

Mol Ther Nucleic Acids. 2019 Dec 6;18:99-109. doi: 10.1016/j.omtn.2019.08.015. Epub 2019 Aug 22.

4.

G-quadruplex ligand RHPS4 radiosensitizes glioblastoma xenograft in vivo through a differential targeting of bulky differentiated- and stem-cancer cells.

Berardinelli F, Tanori M, Muoio D, Buccarelli M, di Masi A, Leone S, Ricci-Vitiani L, Pallini R, Mancuso M, Antoccia A.

J Exp Clin Cancer Res. 2019 Jul 16;38(1):311. doi: 10.1186/s13046-019-1293-x.

5.

Glioblastoma endothelium drives bevacizumab-induced infiltrative growth via modulation of PLXDC1.

Falchetti ML, D'Alessandris QG, Pacioni S, Buccarelli M, Morgante L, Giannetti S, Lulli V, Martini M, Larocca LM, Vakana E, Stancato L, Ricci-Vitiani L, Pallini R.

Int J Cancer. 2019 Mar 15;144(6):1331-1344. doi: 10.1002/ijc.31983. Epub 2018 Dec 16.

6.

Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis.

Buccarelli M, Marconi M, Pacioni S, De Pascalis I, D'Alessandris QG, Martini M, Ascione B, Malorni W, Larocca LM, Pallini R, Ricci-Vitiani L, Matarrese P.

Cell Death Dis. 2018 Aug 6;9(8):841. doi: 10.1038/s41419-018-0864-7.

7.

VEGF-121 plasma level as biomarker for response to anti-angiogenetic therapy in recurrent glioblastoma.

Martini M, de Pascalis I, D'Alessandris QG, Fiorentino V, Pierconti F, Marei HE, Ricci-Vitiani L, Pallini R, Larocca LM.

BMC Cancer. 2018 May 10;18(1):553. doi: 10.1186/s12885-018-4442-2.

8.

Endothelial trans-differentiation in glioblastoma recurring after radiotherapy.

De Pascalis I, Morgante L, Pacioni S, D'Alessandris QG, Giannetti S, Martini M, Ricci-Vitiani L, Malinverno M, Dejana E, Larocca LM, Pallini R.

Mod Pathol. 2018 Sep;31(9):1361-1366. doi: 10.1038/s41379-018-0046-2. Epub 2018 Apr 30.

9.

Metabolic Heterogeneity Evidenced by MRS among Patient-Derived Glioblastoma Multiforme Stem-Like Cells Accounts for Cell Clustering and Different Responses to Drugs.

Grande S, Palma A, Ricci-Vitiani L, Luciani AM, Buccarelli M, Biffoni M, Molinari A, Calcabrini A, D'Amore E, Guidoni L, Pallini R, Viti V, Rosi A.

Stem Cells Int. 2018 Feb 18;2018:3292704. doi: 10.1155/2018/3292704. eCollection 2018.

10.

The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells.

Atzori MG, Tentori L, Ruffini F, Ceci C, Lisi L, Bonanno E, Scimeca M, Eskilsson E, Daubon T, Miletic H, Ricci Vitiani L, Pallini R, Navarra P, Bjerkvig R, D'Atri S, Lacal PM, Graziani G.

J Exp Clin Cancer Res. 2017 Aug 10;36(1):106. doi: 10.1186/s13046-017-0577-2.

11.

Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma.

Haas TL, Sciuto MR, Brunetto L, Valvo C, Signore M, Fiori ME, di Martino S, Giannetti S, Morgante L, Boe A, Patrizii M, Warnken U, Schnölzer M, Ciolfi A, Di Stefano C, Biffoni M, Ricci-Vitiani L, Pallini R, De Maria R.

Cell Stem Cell. 2017 Jul 6;21(1):35-50.e9. doi: 10.1016/j.stem.2017.04.009. Epub 2017 Jun 9.

12.

Human mesenchymal stromal cells inhibit tumor growth in orthotopic glioblastoma xenografts.

Pacioni S, D'Alessandris QG, Giannetti S, Morgante L, Coccè V, Bonomi A, Buccarelli M, Pascucci L, Alessandri G, Pessina A, Ricci-Vitiani L, Falchetti ML, Pallini R.

Stem Cell Res Ther. 2017 Mar 9;8(1):53. doi: 10.1186/s13287-017-0516-3.

13.

A three-microRNA signature identifies two subtypes of glioblastoma patients with different clinical outcomes.

Marziali G, Buccarelli M, Giuliani A, Ilari R, Grande S, Palma A, D'Alessandris QG, Martini M, Biffoni M, Pallini R, Ricci-Vitiani L.

Mol Oncol. 2017 Sep;11(9):1115-1129. doi: 10.1002/1878-0261.12047. Epub 2017 Jul 13.

14.

The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response.

D'Alessandris QG, Biffoni M, Martini M, Runci D, Buccarelli M, Cenci T, Signore M, Stancato L, Olivi A, De Maria R, Larocca LM, Ricci-Vitiani L, Pallini R.

Neuro Oncol. 2017 Aug 1;19(8):1097-1108. doi: 10.1093/neuonc/now304.

15.

RYK promotes the stemness of glioblastoma cells via the WNT/ β-catenin pathway.

Adamo A, Fiore D, De Martino F, Roscigno G, Affinito A, Donnarumma E, Puoti I, Ricci Vitiani L, Pallini R, Quintavalle C, Condorelli G.

Oncotarget. 2017 Feb 21;8(8):13476-13487. doi: 10.18632/oncotarget.14564.

16.

A combined microRNA-based targeted therapeutic approach to eradicate glioblastoma stem-like cells.

Esposito CL, Nuzzo S, Kumar SA, Rienzo A, Lawrence CL, Pallini R, Shaw L, Alder JE, Ricci-Vitiani L, Catuogno S, de Franciscis V.

J Control Release. 2016 Sep 28;238:43-57. doi: 10.1016/j.jconrel.2016.07.032. Epub 2016 Jul 21.

PMID:
27448441
17.

UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response.

Signore M, Buccarelli M, Pilozzi E, De Luca G, Cappellari M, Fanciulli M, Goeman F, Melucci E, Biffoni M, Ricci-Vitiani L.

Oncotarget. 2016 Jul 12;7(28):44113-44128. doi: 10.18632/oncotarget.9859.

18.

Cancer Stem Cell-Based Models of Colorectal Cancer Reveal Molecular Determinants of Therapy Resistance.

De Angelis ML, Zeuner A, Policicchio E, Russo G, Bruselles A, Signore M, Vitale S, De Luca G, Pilozzi E, Boe A, Stassi G, Ricci-Vitiani L, Amoreo CA, Pagliuca A, Francescangeli F, Tartaglia M, De Maria R, Baiocchi M.

Stem Cells Transl Med. 2016 Apr;5(4):511-23. doi: 10.5966/sctm.2015-0214. Epub 2016 Mar 8.

19.

Metabolic/Proteomic Signature Defines Two Glioblastoma Subtypes With Different Clinical Outcome.

Marziali G, Signore M, Buccarelli M, Grande S, Palma A, Biffoni M, Rosi A, D'Alessandris QG, Martini M, Larocca LM, De Maria R, Pallini R, Ricci-Vitiani L.

Sci Rep. 2016 Feb 9;6:21557. doi: 10.1038/srep21557.

20.

miR-135b suppresses tumorigenesis in glioblastoma stem-like cells impairing proliferation, migration and self-renewal.

Lulli V, Buccarelli M, Martini M, Signore M, Biffoni M, Giannetti S, Morgante L, Marziali G, Ilari R, Pagliuca A, Larocca LM, De Maria R, Pallini R, Ricci-Vitiani L.

Oncotarget. 2015 Nov 10;6(35):37241-56. doi: 10.18632/oncotarget.5925.

21.

Potentiation of temozolomide antitumor effect by purine receptor ligands able to restrain the in vitro growth of human glioblastoma stem cells.

D'Alimonte I, Nargi E, Zuccarini M, Lanuti P, Di Iorio P, Giuliani P, Ricci-Vitiani L, Pallini R, Caciagli F, Ciccarelli R.

Purinergic Signal. 2015 Sep;11(3):331-46. doi: 10.1007/s11302-015-9454-7. Epub 2015 May 15.

22.

Glioblastoma stem cells: radiobiological response to ionising radiations of different qualities.

Pecchia I, Dini V, Ricci-Vitiani L, Biffoni M, Balduzzi M, Fratini E, Belli M, Campa A, Esposito G, Cirrone G, Romano F, Stancampiano C, Pelacchi F, Pallini R, Tabocchini MA.

Radiat Prot Dosimetry. 2015 Sep;166(1-4):374-8. doi: 10.1093/rpd/ncv299. Epub 2015 May 11.

PMID:
25969527
23.

A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology.

Tate CM, Mc Entire J, Pallini R, Vakana E, Wyss L, Blosser W, Ricci-Vitiani L, D'Alessandris QG, Morgante L, Giannetti S, Larocca LM, Todaro M, Benfante A, Colorito ML, Stassi G, De Maria R, Rowlinson S, Stancato L.

PLoS One. 2015 Apr 28;10(4):e0125697. doi: 10.1371/journal.pone.0125697. eCollection 2015.

24.

Antimicrobial and antioxidant amphiphilic random copolymers to address medical device-centered infections.

Taresco V, Crisante F, Francolini I, Martinelli A, D'Ilario L, Ricci-Vitiani L, Buccarelli M, Pietrelli L, Piozzi A.

Acta Biomater. 2015 Aug;22:131-40. doi: 10.1016/j.actbio.2015.04.023. Epub 2015 Apr 25.

PMID:
25917843
25.

Cannabidiol stimulates Aml-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner.

Nabissi M, Morelli MB, Amantini C, Liberati S, Santoni M, Ricci-Vitiani L, Pallini R, Santoni G.

Int J Cancer. 2015 Oct 15;137(8):1855-69. doi: 10.1002/ijc.29573. Epub 2015 May 8.

26.

High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells.

Puglisi MA, Cenciarelli C, Tesori V, Cappellari M, Martini M, Di Francesco AM, Giorda E, Carsetti R, Ricci-Vitiani L, Gasbarrini A.

J Pathol. 2015 Aug;236(4):479-90. doi: 10.1002/path.4545. Epub 2015 May 12.

PMID:
25875314
27.

VEGF isoforms as outcome biomarker for anti-angiogenic therapy in recurrent glioblastoma.

D'Alessandris QG, Martini M, Cenci T, Capo G, Ricci-Vitiani L, Larocca LM, Pallini R.

Neurology. 2015 May 5;84(18):1906-8. doi: 10.1212/WNL.0000000000001543. Epub 2015 Apr 10. No abstract available.

PMID:
25862796
28.

(1) H NMR spectroscopy of glioblastoma stem-like cells identifies alpha-aminoadipate as a marker of tumor aggressiveness.

Rosi A, Ricci-Vitiani L, Biffoni M, Grande S, Luciani AM, Palma A, Runci D, Cappellari M, De Maria R, Guidoni L, Pallini R, Viti V.

NMR Biomed. 2015 Mar;28(3):317-26. doi: 10.1002/nbm.3254. Epub 2015 Jan 8.

PMID:
25581615
29.

Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo.

Signore M, Pelacchi F, di Martino S, Runci D, Biffoni M, Giannetti S, Morgante L, De Majo M, Petricoin EF, Stancato L, Larocca LM, De Maria R, Pallini R, Ricci-Vitiani L.

Cell Death Dis. 2014 May 8;5:e1223. doi: 10.1038/cddis.2014.188.

30.

Salinomycin potentiates the cytotoxic effects of TRAIL on glioblastoma cell lines.

Calzolari A, Saulle E, De Angelis ML, Pasquini L, Boe A, Pelacchi F, Ricci-Vitiani L, Baiocchi M, Testa U.

PLoS One. 2014 Apr 16;9(4):e94438. doi: 10.1371/journal.pone.0094438. eCollection 2014.

31.

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide.

Tentori L, Ricci-Vitiani L, Muzi A, Ciccarone F, Pelacchi F, Calabrese R, Runci D, Pallini R, Caiafa P, Graziani G.

BMC Cancer. 2014 Mar 5;14:151. doi: 10.1186/1471-2407-14-151.

32.

Gene expression analysis of PTEN positive glioblastoma stem cells identifies DUB3 and Wee1 modulation in a cell differentiation model.

Forte S, Pagliuca A, Maniscalchi ET, Gulino R, Calabrese G, Ricci-Vitiani L, Pallini R, Signore M, Parenti R, De Maria R, Gulisano M.

PLoS One. 2013 Dec 12;8(12):e81432. doi: 10.1371/journal.pone.0081432. eCollection 2013.

33.

1H NMR detects different metabolic profiles in glioblastoma stem-like cells.

Guidoni L, Ricci-Vitiani L, Rosi A, Palma A, Grande S, Luciani AM, Pelacchi F, di Martino S, Colosimo C, Biffoni M, De Maria R, Pallini R, Viti V.

NMR Biomed. 2014 Feb;27(2):129-45. doi: 10.1002/nbm.3044. Epub 2013 Oct 21.

PMID:
24142746
34.

Chemotherapy of skull base chordoma tailored on responsiveness of patient-derived tumor cells to rapamycin.

Ricci-Vitiani L, Runci D, D'Alessandris QG, Cenci T, Martini M, Bianchi F, Maira G, Stancato L, De Maria R, Larocca LM, Pallini R.

Neoplasia. 2013 Jul;15(7):773-82.

35.

Type-3 metabotropic glutamate receptors regulate chemoresistance in glioma stem cells, and their levels are inversely related to survival in patients with malignant gliomas.

Ciceroni C, Bonelli M, Mastrantoni E, Niccolini C, Laurenza M, Larocca LM, Pallini R, Traficante A, Spinsanti P, Ricci-Vitiani L, Arcella A, De Maria R, Nicoletti F, Battaglia G, Melchiorri D.

Cell Death Differ. 2013 Mar;20(3):396-407. doi: 10.1038/cdd.2012.150. Epub 2012 Nov 23.

36.

Epigenetic silencing of Id4 identifies a glioblastoma subgroup with a better prognosis as a consequence of an inhibition of angiogenesis.

Martini M, Cenci T, D'Alessandris GQ, Cesarini V, Cocomazzi A, Ricci-Vitiani L, De Maria R, Pallini R, Larocca LM.

Cancer. 2013 Mar 1;119(5):1004-12. doi: 10.1002/cncr.27821. Epub 2012 Nov 6.

37.

Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression.

Pagliuca A, Valvo C, Fabrizi E, di Martino S, Biffoni M, Runci D, Forte S, De Maria R, Ricci-Vitiani L.

Oncogene. 2013 Oct;32(40):4806-13. doi: 10.1038/onc.2012.495. Epub 2012 Nov 5.

PMID:
23128394
38.

Proliferation state and polo-like kinase1 dependence of tumorigenic colon cancer cells.

Francescangeli F, Patrizii M, Signore M, Federici G, Di Franco S, Pagliuca A, Baiocchi M, Biffoni M, Ricci Vitiani L, Todaro M, De Maria R, Zeuner A.

Stem Cells. 2012 Sep;30(9):1819-30. doi: 10.1002/stem.1163.

39.

A BMP7 variant inhibits the tumorigenic potential of glioblastoma stem-like cells.

Tate CM, Pallini R, Ricci-Vitiani L, Dowless M, Shiyanova T, D'Alessandris GQ, Morgante L, Giannetti S, Larocca LM, di Martino S, Rowlinson SW, De Maria R, Stancato L.

Cell Death Differ. 2012 Oct;19(10):1644-54. doi: 10.1038/cdd.2012.44. Epub 2012 Apr 27.

40.

The transient receptor potential vanilloid-2 cation channel impairs glioblastoma stem-like cell proliferation and promotes differentiation.

Morelli MB, Nabissi M, Amantini C, Farfariello V, Ricci-Vitiani L, di Martino S, Pallini R, Larocca LM, Caprodossi S, Santoni M, De Maria R, Santoni G.

Int J Cancer. 2012 Oct 1;131(7):E1067-77. doi: 10.1002/ijc.27588. Epub 2012 Apr 27.

41.

Expression of EGFRvIII in glioblastoma: prognostic significance revisited.

Montano N, Cenci T, Martini M, D'Alessandris QG, Pelacchi F, Ricci-Vitiani L, Maira G, De Maria R, Larocca LM, Pallini R.

Neoplasia. 2011 Dec;13(12):1113-21.

42.

CPTH6, a thiazole derivative, induces histone hypoacetylation and apoptosis in human leukemia cells.

Trisciuoglio D, Ragazzoni Y, Pelosi A, Desideri M, Carradori S, Gabellini C, Maresca G, Nescatelli R, Secci D, Bolasco A, Bizzarri B, Cavaliere C, D'Agnano I, Filetici P, Ricci-Vitiani L, Rizzo MG, Del Bufalo D.

Clin Cancer Res. 2012 Jan 15;18(2):475-86. doi: 10.1158/1078-0432.CCR-11-0579. Epub 2011 Nov 8.

43.

Knockdown of ubiquitin ligases in glioblastoma cancer stem cells leads to cell death and differentiation.

Low J, Blosser W, Dowless M, Ricci-Vitiani L, Pallini R, de Maria R, Stancato L.

J Biomol Screen. 2012 Feb;17(2):152-62. doi: 10.1177/1087057111422565. Epub 2011 Sep 28.

PMID:
21956171
44.

Targeting apoptosis pathways in cancer stem cells.

Signore M, Ricci-Vitiani L, De Maria R.

Cancer Lett. 2013 May 28;332(2):374-82. doi: 10.1016/j.canlet.2011.01.013. Epub 2011 Feb 10. Review.

PMID:
21315505
45.

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells.

Ricci-Vitiani L, Pallini R, Biffoni M, Todaro M, Invernici G, Cenci T, Maira G, Parati EA, Stassi G, Larocca LM, De Maria R.

Nature. 2010 Dec 9;468(7325):824-8. doi: 10.1038/nature09557. Epub 2010 Nov 21. Erratum in: Nature. 2011 Jan 20;469(7330):432. Nature. 2011 Sep 8;477(7363):238.

PMID:
21102434
46.

Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.

Lombardo Y, Scopelliti A, Cammareri P, Todaro M, Iovino F, Ricci-Vitiani L, Gulotta G, Dieli F, de Maria R, Stassi G.

Gastroenterology. 2011 Jan;140(1):297-309. doi: 10.1053/j.gastro.2010.10.005. Epub 2010 Oct 14.

PMID:
20951698
47.

Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis.

Pallini R, Ricci-Vitiani L, Montano N, Mollinari C, Biffoni M, Cenci T, Pierconti F, Martini M, De Maria R, Larocca LM.

Cancer. 2011 Jan 1;117(1):162-74. doi: 10.1002/cncr.25581. Epub 2010 Aug 30. Erratum in: Cancer. 2016 Oct;122(19):3090.

48.

Therapeutic implications of colon cancer stem cells.

Fabrizi E, di Martino S, Pelacchi F, Ricci-Vitiani L.

World J Gastroenterol. 2010 Aug 21;16(31):3871-7. Review.

49.

PED interacts with Rac1 and regulates cell migration/invasion processes in human non-small cell lung cancer cells.

Zanca C, Cozzolino F, Quintavalle C, Di Costanzo S, Ricci-Vitiani L, Santoriello M, Monti M, Pucci P, Condorelli G.

J Cell Physiol. 2010 Oct;225(1):63-72. doi: 10.1002/jcp.22197.

PMID:
20648624
50.

Knockdown of cancer testis antigens modulates neural stem cell marker expression in glioblastoma tumor stem cells.

Low J, Dowless M, Shiyanova T, Rowlinson S, Ricci-Vitiani L, de Maria R, Pallini R, Stancato L.

J Biomol Screen. 2010 Aug;15(7):830-9. doi: 10.1177/1087057110374983. Epub 2010 Jul 16.

PMID:
20639497

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