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Items: 1 to 50 of 162

1.

Treatment of Autosomal Dominant Hypocalcemia Type 1 With the Calcilytic NPSP795 (SHP635).

Roberts MS, Gafni RI, Brillante B, Guthrie LC, Streit J, Gash D, Gelb J, Krusinska E, Brennan SC, Schepelmann M, Riccardi D, Bin Khayat ME, Ward DT, Nemeth EF, Rosskamp R, Collins MT.

J Bone Miner Res. 2019 Sep;34(9):1609-1618. doi: 10.1002/jbmr.3747. Epub 2019 Jul 26.

PMID:
31063613
2.

Cys.sqlite: A Structured-Information Approach to the Comprehensive Analysis of Cysteine Disulfide Bonds in the Protein Databank.

Fobe TL, Kazakov A, Riccardi D.

J Chem Inf Model. 2019 Feb 25;59(2):931-943. doi: 10.1021/acs.jcim.8b00950. Epub 2019 Feb 15.

PMID:
30694665
3.

Environmental Mercury Chemistry - In Silico.

Asaduzzaman A, Riccardi D, Afaneh AT, Cooper SJ, Smith JC, Wang F, Parks JM, Schreckenbach G.

Acc Chem Res. 2019 Feb 19;52(2):379-388. doi: 10.1021/acs.accounts.8b00454. Epub 2019 Jan 28.

PMID:
30689347
4.

Highly mechanosensitive ion channels from graphene-embedded crown ethers.

Fang A, Kroenlein K, Riccardi D, Smolyanitsky A.

Nat Mater. 2019 Jan;18(1):76-81. doi: 10.1038/s41563-018-0220-4. Epub 2018 Nov 26.

PMID:
30478453
5.

The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway.

Bazúa-Valenti S, Rojas-Vega L, Castañeda-Bueno M, Barrera-Chimal J, Bautista R, Cervantes-Pérez LG, Vázquez N, Plata C, Murillo-de-Ozores AR, González-Mariscal L, Ellison DH, Riccardi D, Bobadilla NA, Gamba G.

J Am Soc Nephrol. 2018 Jul;29(7):1838-1848. doi: 10.1681/ASN.2017111155. Epub 2018 May 30.

6.

Polygenicity and Epistasis Underlie Fitness-Proximal Traits in the Caenorhabditis elegans Multiparental Experimental Evolution (CeMEE) Panel.

Noble LM, Chelo I, Guzella T, Afonso B, Riccardi DD, Ammerman P, Dayarian A, Carvalho S, Crist A, Pino-Querido A, Shraiman B, Rockman MV, Teotónio H.

Genetics. 2017 Dec;207(4):1663-1685. doi: 10.1534/genetics.117.300406. Epub 2017 Oct 24.

7.

Ensemble docking to difficult targets in early-stage drug discovery: Methodology and application to fibroblast growth factor 23.

Velazquez HA, Riccardi D, Xiao Z, Quarles LD, Yates CR, Baudry J, Smith JC.

Chem Biol Drug Des. 2018 Feb;91(2):491-504. doi: 10.1111/cbdd.13110. Epub 2017 Nov 3.

PMID:
28944571
8.

Adipose tissue fibrosis in human cancer cachexia: the role of TGFβ pathway.

Alves MJ, Figuerêdo RG, Azevedo FF, Cavallaro DA, Neto NI, Lima JD, Matos-Neto E, Radloff K, Riccardi DM, Camargo RG, De Alcântara PS, Otoch JP, Junior ML, Seelaender M.

BMC Cancer. 2017 Mar 14;17(1):190. doi: 10.1186/s12885-017-3178-8.

9.

Phenotypic characterization of Grm1crv4 mice reveals a functional role for the type 1 metabotropic glutamate receptor in bone mineralization.

Musante I, Mattinzoli D, Otescu LA, Bossi S, Ikehata M, Gentili C, Cangemi G, Gatti C, Emionite L, Messa P, Ravazzolo R, Rastaldi MP, Riccardi D, Puliti A.

Bone. 2017 Jan;94:114-123. doi: 10.1016/j.bone.2016.10.025. Epub 2016 Oct 27.

PMID:
27989650
10.

A computationally identified compound antagonizes excess FGF-23 signaling in renal tubules and a mouse model of hypophosphatemia.

Xiao Z, Riccardi D, Velazquez HA, Chin AL, Yates CR, Carrick JD, Smith JC, Baudry J, Quarles LD.

Sci Signal. 2016 Nov 22;9(455):ra113. Erratum in: Sci Signal. 2016 Dec 06;9(457):er3.

11.

Corrigendum to FGF23-regulated production of fetuin-A (AHSG) in osteocytes [Bone 83 (2016) 35-47].

Mattinzoli D, Rastaldi MP, Ikehata M, Armelloni S, Pignatari C, Giardino LA, Li M, Alfieri CM, Regalia A, Riccardi D, Messa P.

Bone. 2016 Dec;93:236. doi: 10.1016/j.bone.2016.03.008. Epub 2016 Mar 28. No abstract available.

PMID:
27772733
12.

Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA.

Kemp PJ, Rushton DJ, Yarova PL, Schnell C, Geater C, Hancock JM, Wieland A, Hughes A, Badder L, Cope E, Riccardi D, Randall AD, Brown JT, Allen ND, Telezhkin V.

J Physiol. 2016 Nov 15;594(22):6583-6594. doi: 10.1113/JP270655. Review.

13.

Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia.

Scognamiglio PL, Di Natale C, Leone M, Cascella R, Cecchi C, Lirussi L, Antoniali G, Riccardi D, Morelli G, Tell G, Chiti F, Marasco D.

Oncotarget. 2016 Sep 13;7(37):59129-59143. doi: 10.18632/oncotarget.10991.

14.

White adipose tissue cells and the progression of cachexia: inflammatory pathways.

Neves RX, Rosa-Neto JC, Yamashita AS, Matos-Neto EM, Riccardi DM, Lira FS, Batista ML Jr, Seelaender M.

J Cachexia Sarcopenia Muscle. 2016 May;7(2):193-203. doi: 10.1002/jcsm.12041. Epub 2015 Jul 7.

15.

The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length.

Cook DE, Zdraljevic S, Tanny RE, Seo B, Riccardi DD, Noble LM, Rockman MV, Alkema MJ, Braendle C, Kammenga JE, Wang J, Kruglyak L, Félix MA, Lee J, Andersen EC.

Genetics. 2016 Sep;204(1):371-83. doi: 10.1534/genetics.116.191148. Epub 2016 Jul 22.

16.

Localization and function of the renal calcium-sensing receptor.

Riccardi D, Valenti G.

Nat Rev Nephrol. 2016 Jul;12(7):414-25. doi: 10.1038/nrneph.2016.59. Epub 2016 May 9. Review.

PMID:
27157444
17.

The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR.

Brennan SC, Wilkinson WJ, Tseng HE, Finney B, Monk B, Dibble H, Quilliam S, Warburton D, Galietta LJ, Kemp PJ, Riccardi D.

Sci Rep. 2016 Feb 25;6:21975. doi: 10.1038/srep21975.

18.

Systemic Inflammation in Cachexia - Is Tumor Cytokine Expression Profile the Culprit?

de Matos-Neto EM, Lima JD, de Pereira WO, Figuerêdo RG, Riccardi DM, Radloff K, das Neves RX, Camargo RG, Maximiano LF, Tokeshi F, Otoch JP, Goldszmid R, Câmara NO, Trinchieri G, de Alcântara PS, Seelaender M.

Front Immunol. 2015 Dec 24;6:629. doi: 10.3389/fimmu.2015.00629. eCollection 2015.

19.

Comparative expression of the extracellular calcium-sensing receptor in the mouse, rat, and human kidney.

Graca JA, Schepelmann M, Brennan SC, Reens J, Chang W, Yan P, Toka H, Riccardi D, Price SA.

Am J Physiol Renal Physiol. 2016 Mar 15;310(6):F518-33. doi: 10.1152/ajprenal.00208.2015. Epub 2015 Dec 9.

20.

The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure.

Schepelmann M, Yarova PL, Lopez-Fernandez I, Davies TS, Brennan SC, Edwards PJ, Aggarwal A, Graça J, Rietdorf K, Matchkov V, Fenton RA, Chang W, Krssak M, Stewart A, Broadley KJ, Ward DT, Price SA, Edwards DH, Kemp PJ, Riccardi D.

Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C193-204. doi: 10.1152/ajpcell.00248.2015. Epub 2015 Nov 4.

21.

FGF23-regulated production of Fetuin-A (AHSG) in osteocytes.

Mattinzoli D, Rastaldi MP, Ikehata M, Armelloni S, Pignatari C, Giardino LA, Li M, Alfieri CM, Regalia A, Riccardi D, Messa P.

Bone. 2016 Feb;83:35-47. doi: 10.1016/j.bone.2015.10.008. Epub 2015 Oct 23. Erratum in: Bone. 2016 Dec;93:236.

PMID:
26476373
22.

Natural Variation in plep-1 Causes Male-Male Copulatory Behavior in C. elegans.

Noble LM, Chang AS, McNelis D, Kramer M, Yen M, Nicodemus JP, Riccardi DD, Ammerman P, Phillips M, Islam T, Rockman MV.

Curr Biol. 2015 Oct 19;25(20):2730-7. doi: 10.1016/j.cub.2015.09.019. Epub 2015 Oct 8.

23.

Wild worm embryogenesis harbors ubiquitous polygenic modifier variation.

Paaby AB, White AG, Riccardi DD, Gunsalus KC, Piano F, Rockman MV.

Elife. 2015 Aug 22;4. doi: 10.7554/eLife.09178.

24.

The calcium-sensing receptor: one of a kind.

Lopez-Fernandez I, Schepelmann M, Brennan SC, Yarova PL, Riccardi D.

Exp Physiol. 2015 Dec;100(12):1392-9. doi: 10.1113/EP085137. Epub 2015 Jul 26. Review. No abstract available.

25.

NF-κBp65 and Expression of Its Pro-Inflammatory Target Genes Are Upregulated in the Subcutaneous Adipose Tissue of Cachectic Cancer Patients.

Camargo RG, Riccardi DM, Ribeiro HQ, Carnevali LC Jr, de Matos-Neto EM, Enjiu L, Neves RX, Lima JD, Figuerêdo RG, de Alcântara PS, Maximiano L, Otoch J, Batista M Jr, Püschel G, Seelaender M.

Nutrients. 2015 Jun 4;7(6):4465-79. doi: 10.3390/nu7064465.

26.

Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma.

Yarova PL, Stewart AL, Sathish V, Britt RD Jr, Thompson MA, P Lowe AP, Freeman M, Aravamudan B, Kita H, Brennan SC, Schepelmann M, Davies T, Yung S, Cholisoh Z, Kidd EJ, Ford WR, Broadley KJ, Rietdorf K, Chang W, Bin Khayat ME, Ward DT, Corrigan CJ, T Ward JP, Kemp PJ, Pabelick CM, Prakash YS, Riccardi D.

Sci Transl Med. 2015 Apr 22;7(284):284ra60. doi: 10.1126/scitranslmed.aaa0282. Epub 2015 Apr 22.

27.

HackaMol: An Object-Oriented Modern Perl Library for Molecular Hacking on Multiple Scales.

Riccardi D, Parks JM, Johs A, Smith JC.

J Chem Inf Model. 2015 Apr 27;55(4):721-6. doi: 10.1021/ci500359e. Epub 2015 Apr 2.

PMID:
25793330
28.

The genetic architecture of the genome-wide transcriptional response to ER stress in the mouse.

Chow CY, Wang X, Riccardi D, Wolfner MF, Clark AG.

PLoS Genet. 2015 Feb 4;11(2):e1004924. doi: 10.1371/journal.pgen.1004924. eCollection 2015 Feb.

29.

A new method to investigate how mechanical loading of osteocytes controls osteoblasts.

Vazquez M, Evans BA, Riccardi D, Evans SL, Ralphs JR, Dillingham CM, Mason DJ.

Front Endocrinol (Lausanne). 2014 Dec 9;5:208. doi: 10.3389/fendo.2014.00208. eCollection 2014.

30.

X-ray structure of a Hg2+ complex of mercuric reductase (MerA) and quantum mechanical/molecular mechanical study of Hg2+ transfer between the C-terminal and buried catalytic site cysteine pairs.

Lian P, Guo HB, Riccardi D, Dong A, Parks JM, Xu Q, Pai EF, Miller SM, Wei DQ, Smith JC, Guo H.

Biochemistry. 2014 Nov 25;53(46):7211-22. doi: 10.1021/bi500608u. Epub 2014 Nov 13.

31.

Emerging roles of the extracellular calcium-sensing receptor in nutrient sensing: control of taste modulation and intestinal hormone secretion.

Brennan SC, Davies TS, Schepelmann M, Riccardi D.

Br J Nutr. 2014 Jun;111 Suppl 1:S16-22. Review.

PMID:
24382107
32.

Mercury methylation by HgcA: theory supports carbanion transfer to Hg(II).

Zhou J, Riccardi D, Beste A, Smith JC, Parks JM.

Inorg Chem. 2014 Jan 21;53(2):772-7. doi: 10.1021/ic401992y. Epub 2013 Dec 30.

PMID:
24377658
33.

Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis.

Varma S, Mahavadi P, Sasikumar S, Cushing L, Hyland T, Rosser AE, Riccardi D, Lu J, Kalin TV, Kalinichenko VV, Guenther A, Ramirez MI, Pardo A, Selman M, Warburton D.

Am J Physiol Lung Cell Mol Physiol. 2014 Mar 1;306(5):L405-19. doi: 10.1152/ajplung.00143.2013. Epub 2013 Dec 27.

34.

Fetal calcium regulates branching morphogenesis in the developing human and mouse lung: involvement of voltage-gated calcium channels.

Brennan SC, Finney BA, Lazarou M, Rosser AE, Scherf C, Adriaensen D, Kemp PJ, Riccardi D.

PLoS One. 2013 Nov 25;8(11):e80294. doi: 10.1371/journal.pone.0080294. eCollection 2013.

35.

Considerations on evolution and healing of vertebral fractures.

Klumpp R, Trevisan C, Nava V, Riccardi D, Recalcati W.

Aging Clin Exp Res. 2013 Oct;25 Suppl 1:S75-6. doi: 10.1007/s40520-013-0085-y. Epub 2013 Sep 18.

PMID:
24046049
36.

Surgical versus conservative treatment of distal radius fractures in elderly.

Trevisan C, Klumpp R, Nava V, Riccardi D, Recalcati W.

Aging Clin Exp Res. 2013 Oct;25 Suppl 1:S83-4. doi: 10.1007/s40520-013-0075-0. Epub 2013 Sep 18.

PMID:
24046043
37.

Functional expression of the multimodal extracellular calcium-sensing receptor in pulmonary neuroendocrine cells.

Lembrechts R, Brouns I, Schnorbusch K, Pintelon I, Kemp PJ, Timmermans JP, Riccardi D, Adriaensen D.

J Cell Sci. 2013 Oct 1;126(Pt 19):4490-501. doi: 10.1242/jcs.131656. Epub 2013 Jul 25.

38.

The extracellular calcium-sensing receptor, CaSR, in fetal development.

Riccardi D, Brennan SC, Chang W.

Best Pract Res Clin Endocrinol Metab. 2013 Jun;27(3):443-53. doi: 10.1016/j.beem.2013.02.010. Epub 2013 Mar 26. Review.

39.

Tissue expression and correlation of a panel of urinary biomarkers following cisplatin-induced kidney injury.

Wadey RM, Pinches MG, Jones HB, Riccardi D, Price SA.

Toxicol Pathol. 2014;42(3):591-602. doi: 10.1177/0192623313492044. Epub 2013 Jul 3.

PMID:
23823703
40.

Molecular and clinical analysis of a neonatal severe hyperparathyroidism case caused by a stop mutation in the calcium-sensing receptor extracellular domain representing in effect a human 'knockout'.

Ward DT, Mughal MZ, Ranieri M, Dvorak-Ewell MM, Valenti G, Riccardi D.

Eur J Endocrinol. 2013 Jun 1;169(1):K1-7. doi: 10.1530/EJE-13-0094. Print 2013 Jul.

PMID:
23612447
41.

Cluster-Continuum Calculations of Hydration Free Energies of Anions and Group 12 Divalent Cations.

Riccardi D, Guo HB, Parks JM, Gu B, Liang L, Smith JC.

J Chem Theory Comput. 2013 Jan 8;9(1):555-69. doi: 10.1021/ct300296k. Epub 2012 Dec 6.

PMID:
26589054
42.

Calcium sensing receptor signalling in physiology and cancer.

Brennan SC, Thiem U, Roth S, Aggarwal A, Fetahu ISh, Tennakoon S, Gomes AR, Brandi ML, Bruggeman F, Mentaverri R, Riccardi D, Kallay E.

Biochim Biophys Acta. 2013 Jul;1833(7):1732-44. doi: 10.1016/j.bbamcr.2012.12.011. Epub 2012 Dec 23. Review.

43.

[The Ponseti approach for the treatment of congenital clubfoot].

Riccio I, Riccio V, Riccardi D, Esposito M, Riccardi G.

Pediatr Med Chir. 2012 Jul-Aug;34(4):179-81. Italian. No abstract available.

PMID:
23173409
44.

Parathyroid hormone-independent role for the calcium-sensing receptor in the control of urinary calcium excretion.

Riccardi D.

J Am Soc Nephrol. 2012 Nov;23(11):1766-8. doi: 10.1681/ASN.2012090955. Epub 2012 Oct 18. No abstract available.

45.

Septic arthritis in children.

Riccio V, Riccio I, Porpora G, Riccardi D, Riccardi G.

Pediatr Med Chir. 2012 May-Jun;34(3):123-8.

PMID:
22966724
46.

Allosteric agonists of the calcium receptor (CaR): fluorine and SF5 analogues of cinacalcet.

Chia PW, Brennan SC, Slawin AM, Riccardi D, O'Hagan D.

Org Biomol Chem. 2012 Oct 21;10(39):7922-7.

PMID:
22940747
47.

The calcium-sensing receptor beyond extracellular calcium homeostasis: conception, development, adult physiology, and disease.

Riccardi D, Kemp PJ.

Annu Rev Physiol. 2012;74:271-97. doi: 10.1146/annurev-physiol-020911-153318. Epub 2011 Oct 17. Review.

PMID:
22017175
48.

Antagonizing the calcium-sensing receptor: towards new bone anabolics?

Riccardi D.

Curr Mol Pharmacol. 2012 Jun;5(2):182-8. Review.

PMID:
21787287
49.

Extremely proximal fractures of the fifth metatarsal in the developmental age.

Riccardi G, Riccardi D, Marcarelli M, Del Regno N, Riccio V.

Foot Ankle Int. 2011 May;32(5):S526-32. doi: 10.3113/FAI.2011.0526.

PMID:
21733462
50.

New concepts in calcium-sensing receptor pharmacology and signalling.

Ward DT, Riccardi D.

Br J Pharmacol. 2012 Jan;165(1):35-48. doi: 10.1111/j.1476-5381.2011.01511.x. Review.

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