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Items: 1 to 50 of 291

1.

Hydrogen sulfide impacts on inflammation-induced adipocyte dysfunction.

Comas F, Latorre J, Cussó O, Ortega F, Lluch A, Sabater M, Castells-Nobau A, Ricart W, Ribas X, Costas M, Fernández-Real JM, Moreno-Navarrete JM.

Food Chem Toxicol. 2019 May 30;131:110543. doi: 10.1016/j.fct.2019.05.051. [Epub ahead of print]

PMID:
31154084
2.

Cytoskeletal transgelin 2 contributes to gender-dependent adipose tissue expandability and immune function.

Ortega FJ, Moreno-Navarrete JM, Mercader JM, Gómez-Serrano M, García-Santos E, Latorre J, Lluch A, Sabater M, Caballano-Infantes E, Guzmán R, Macías-González M, Buxo M, Gironés J, Vilallonga R, Naon D, Botas P, Delgado E, Corella D, Burcelin R, Frühbeck G, Ricart W, Simó R, Castrillon-Rodríguez I, Tinahones FJ, Bosch F, Vidal-Puig A, Malagón MM, Peral B, Zorzano A, Fernández-Real JM.

FASEB J. 2019 May 30:fj201900479R. doi: 10.1096/fj.201900479R. [Epub ahead of print]

PMID:
31145872
3.

Comparative and functional analysis of plasma membrane-derived extracellular vesicles from obese vs. nonobese women.

Santamaria-Martos F, Benitez ID, Latorre J, Lluch A, Moreno-Navarrete JM, Sabater M, Ricart W, Sanchez de la Torre M, Mora S, Fernández-Real JM, Ortega FJ.

Clin Nutr. 2019 Apr 17. pii: S0261-5614(19)30163-3. doi: 10.1016/j.clnu.2019.04.008. [Epub ahead of print]

PMID:
31036413
4.

Glycated Hemoglobin, but not Insulin Sensitivity, is Associated with Memory in Subjects with Obesity.

Arnoriaga Rodríguez M, Blasco G, Coll C, Biarnés C, Contreras-Rodríguez O, Garre-Olmo J, Puig J, Gich J, Ricart W, Ramió-Torrentà L, Fernández-Real JM.

Obesity (Silver Spring). 2019 Jun;27(6):932-942. doi: 10.1002/oby.22457. Epub 2019 Apr 15.

PMID:
30985999
5.

Glutamate interactions with obesity, insulin resistance, cognition and gut microbiota composition.

Palomo-Buitrago ME, Sabater-Masdeu M, Moreno-Navarrete JM, Caballano-Infantes E, Arnoriaga-Rodríguez M, Coll C, Ramió L, Palomino-Schätzlein M, Gutiérrez-Carcedo P, Pérez-Brocal V, Simó R, Moya A, Ricart W, Herance JR, Fernández-Real JM.

Acta Diabetol. 2019 May;56(5):569-579. doi: 10.1007/s00592-019-01313-w. Epub 2019 Mar 19.

PMID:
30888539
6.

Neuregulin 4 Is a Novel Marker of Beige Adipocyte Precursor Cells in Human Adipose Tissue.

Comas F, Martínez C, Sabater M, Ortega F, Latorre J, Díaz-Sáez F, Aragonés J, Camps M, Gumà A, Ricart W, Fernández-Real JM, Moreno-Navarrete JM.

Front Physiol. 2019 Jan 31;10:39. doi: 10.3389/fphys.2019.00039. eCollection 2019.

7.

Decreased TLR3 in Hyperplastic Adipose Tissue, Blood and Inflamed Adipocytes is Related to Metabolic Inflammation.

Latorre J, Moreno-Navarrete JM, Sabater M, Buxo M, Rodriguez-Hermosa JI, Girones J, Fort JM, Vilallonga R, Ricart W, Simo R, Fernandez-Real JM, Ortega FJ.

Cell Physiol Biochem. 2018;51(3):1051-1068. doi: 10.1159/000495487. Epub 2018 Nov 26.

8.

Adipose TSHB in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence.

Moreno-Navarrete JM, Liñares-Pose L, Sabater M, Rial-Pensado E, Comas F, Jové M, Latorre J, Ortega F, Ricart W, Portero-Otin M, López M, Fernández-Real JM.

Cell Physiol Biochem. 2018;51(1):142-153. doi: 10.1159/000495170. Epub 2018 Nov 16.

9.

Adipose tissue TSH as a new modulator of human adipocyte mitochondrial function.

Comas F, Lluch A, Sabater M, Latorre J, Ortega F, Ricart W, López M, Fernández-Real JM, Moreno-Navarrete JM.

Int J Obes (Lond). 2018 Sep 11. doi: 10.1038/s41366-018-0203-1. [Epub ahead of print]

PMID:
30206337
10.

Publisher Correction: Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

Hoyles L, Fernández-Real JM, Federici M, Serino M, Abbott J, Charpentier J, Heymes C, Luque JL, Anthony E, Barton RH, Chilloux J, Myridakis A, Martinez-Gili L, Moreno-Navarrete JM, Benhamed F, Azalbert V, Blasco-Baque V, Puig J, Xifra G, Ricart W, Tomlinson C, Woodbridge M, Cardellini M, Davato F, Cardolini I, Porzio O, Gentileschi P, Lopez F, Foufelle F, Butcher SA, Holmes E, Nicholson JK, Postic C, Burcelin R, Dumas ME.

Nat Med. 2018 Oct;24(10):1628. doi: 10.1038/s41591-018-0169-5.

PMID:
30093731
11.

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

Hoyles L, Fernández-Real JM, Federici M, Serino M, Abbott J, Charpentier J, Heymes C, Luque JL, Anthony E, Barton RH, Chilloux J, Myridakis A, Martinez-Gili L, Moreno-Navarrete JM, Benhamed F, Azalbert V, Blasco-Baque V, Puig J, Xifra G, Ricart W, Tomlinson C, Woodbridge M, Cardellini M, Davato F, Cardolini I, Porzio O, Gentileschi P, Lopez F, Foufelle F, Butcher SA, Holmes E, Nicholson JK, Postic C, Burcelin R, Dumas ME.

Nat Med. 2018 Jul;24(7):1070-1080. doi: 10.1038/s41591-018-0061-3. Epub 2018 Jun 25. Erratum in: Nat Med. 2018 Aug 9;:.

12.

An Epigenetic Signature in Adipose Tissue Is Linked to Nicotinamide N-Methyltransferase Gene Expression.

Crujeiras AB, Pissios P, Moreno-Navarrete JM, Diaz-Lagares A, Sandoval J, Gomez A, Ricart W, Esteller M, Casanueva FF, Fernandez-Real JM.

Mol Nutr Food Res. 2018 Apr 24:e1700933. doi: 10.1002/mnfr.201700933. [Epub ahead of print]

PMID:
29688621
13.

Decreased iron stores are associated with cardiovascular disease in patients with type 2 diabetes both cross-sectionally and longitudinally.

Suárez-Ortegón MF, McLachlan S, Price AH, Fernández-Balsells M, Franch-Nadal J, Mata-Cases M, Barrot-de la Puente J, Mundet-Tudurí X, Mauricio D, Ricart W, Wild SH, Strachan MWJ, Price JF, Fernández-Real JM.

Atherosclerosis. 2018 May;272:193-199. doi: 10.1016/j.atherosclerosis.2018.03.028. Epub 2018 Mar 21.

PMID:
29625295
14.

Plasma ANGPTL-4 is Associated with Obesity and Glucose Tolerance: Cross-Sectional and Longitudinal Findings.

Barja-Fernandez S, Moreno-Navarrete JM, Folgueira C, Xifra G, Sabater M, Castelao C, FernØ J, Leis R, Diéguez C, Casanueva FF, Ricart W, Seoane LM, Fernandez-Real JM, Nogueiras R.

Mol Nutr Food Res. 2018 May;62(10):e1800060. doi: 10.1002/mnfr.201800060. Epub 2018 Apr 30.

PMID:
29536615
15.

The gut mycobiome composition is linked to carotid atherosclerosis.

Chacón MR, Lozano-Bartolomé J, Portero-Otín M, Rodríguez MM, Xifra G, Puig J, Blasco G, Ricart W, Chaves FJ, Fernández-Real JM.

Benef Microbes. 2018 Feb 27;9(2):185-198. doi: 10.3920/BM2017.0029. Epub 2017 Nov 10.

PMID:
29124969
16.

Gut Microbiota Interacts with Markers of Adipose Tissue Browning, Insulin Action and Plasma Acetate in Morbid Obesity.

Moreno-Navarrete JM, Serino M, Blasco-Baque V, Azalbert V, Barton RH, Cardellini M, Latorre J, Ortega F, Sabater-Masdeu M, Burcelin R, Dumas ME, Ricart W, Federici M, Fernández-Real JM.

Mol Nutr Food Res. 2018 Feb;62(3). doi: 10.1002/mnfr.201700721. Epub 2017 Dec 29.

17.

Obesity status influences the relationship among serum osteocalcin, iron stores and insulin sensitivity.

Xifra G, Moreno-Navarrete JM, Moreno M, Ricart W, Fernández-Real JM.

Clin Nutr. 2018 Dec;37(6 Pt A):2091-2096. doi: 10.1016/j.clnu.2017.10.001. Epub 2017 Oct 6.

PMID:
29050649
18.

Heme Biosynthetic Pathway is Functionally Linked to Adipogenesis via Mitochondrial Respiratory Activity.

Moreno-Navarrete JM, Rodríguez A, Ortega F, Becerril S, Girones J, Sabater-Masdeu M, Latorre J, Ricart W, Frühbeck G, Fernández-Real JM.

Obesity (Silver Spring). 2017 Oct;25(10):1723-1733. doi: 10.1002/oby.21956. Epub 2017 Aug 31.

19.

Increased adipose tissue heme levels and exportation are associated with altered systemic glucose metabolism.

Moreno-Navarrete JM, Rodríguez A, Ortega F, Becerril S, Sabater-Masdeu M, Latorre J, Ricart W, Frühbeck G, Fernández-Real JM.

Sci Rep. 2017 Jul 13;7(1):5305. doi: 10.1038/s41598-017-05597-2.

20.

Neuroinflammation in obesity: circulating lipopolysaccharide-binding protein associates with brain structure and cognitive performance.

Moreno-Navarrete JM, Blasco G, Puig J, Biarnés C, Rivero M, Gich J, Fernández-Aranda F, Garre-Olmo J, Ramió-Torrentà L, Alberich-Bayarri Á, García-Castro F, Pedraza S, Ricart W, Fernández-Real JM.

Int J Obes (Lond). 2017 Nov;41(11):1627-1635. doi: 10.1038/ijo.2017.162. Epub 2017 Jul 7.

PMID:
28684860
21.

TSHB mRNA is linked to cholesterol metabolism in adipose tissue.

Moreno-Navarrete JM, Moreno M, Ortega F, Xifra G, Hong S, Asara JM, Serrano JCE, Jové M, Pissios P, Blüher M, Ricart W, Portero-Otin M, Fernández-Real JM.

FASEB J. 2017 Oct;31(10):4482-4491. doi: 10.1096/fj.201700161R. Epub 2017 Jun 23.

22.

The Gut Metagenome Changes in Parallel to Waist Circumference, Brain Iron Deposition, and Cognitive Function.

Blasco G, Moreno-Navarrete JM, Rivero M, Pérez-Brocal V, Garre-Olmo J, Puig J, Daunis-I-Estadella P, Biarnés C, Gich J, Fernández-Aranda F, Alberich-Bayarri Á, Moya A, Pedraza S, Ricart W, López M, Portero-Otin M, Fernandez-Real JM.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2962-2973. doi: 10.1210/jc.2017-00133.

PMID:
28591831
23.

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug.

Wu H, Esteve E, Tremaroli V, Khan MT, Caesar R, Mannerås-Holm L, Ståhlman M, Olsson LM, Serino M, Planas-Fèlix M, Xifra G, Mercader JM, Torrents D, Burcelin R, Ricart W, Perkins R, Fernàndez-Real JM, Bäckhed F.

Nat Med. 2017 Jul;23(7):850-858. doi: 10.1038/nm.4345. Epub 2017 May 22.

PMID:
28530702
24.

HMOX1 as a marker of iron excess-induced adipose tissue dysfunction, affecting glucose uptake and respiratory capacity in human adipocytes.

Moreno-Navarrete JM, Ortega F, Rodríguez A, Latorre J, Becerril S, Sabater-Masdeu M, Ricart W, Frühbeck G, Fernández-Real JM.

Diabetologia. 2017 May;60(5):915-926. doi: 10.1007/s00125-017-4228-0. Epub 2017 Feb 27.

PMID:
28243792
25.

Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD.

Latorre J, Moreno-Navarrete JM, Mercader JM, Sabater M, Rovira Ò, Gironès J, Ricart W, Fernández-Real JM, Ortega FJ.

Int J Obes (Lond). 2017 Apr;41(4):620-630. doi: 10.1038/ijo.2017.21. Epub 2017 Jan 25.

PMID:
28119530
26.

Adipocyte lipopolysaccharide binding protein (LBP) is linked to a specific lipidomic signature.

Moreno-Navarrete JM, Jové M, Padró T, Boada J, Ortega F, Ricart W, Pamplona R, Badimón L, Portero-Otín M, Fernández-Real JM.

Obesity (Silver Spring). 2017 Feb;25(2):391-400. doi: 10.1002/oby.21711. Epub 2016 Dec 21.

27.

Ferroportin mRNA is down-regulated in granulosa and cervical cells from infertile women.

Moreno-Navarrete JM, López-Navarro E, Candenas L, Pinto F, Ortega FJ, Sabater-Masdeu M, Fernández-Sánchez M, Blasco V, Romero-Ruiz A, Fontán M, Ricart W, Tena-Sempere M, Fernández-Real JM.

Fertil Steril. 2017 Jan;107(1):236-242. doi: 10.1016/j.fertnstert.2016.10.008. Epub 2016 Nov 16.

PMID:
27842994
28.

Are nurses sufficiently well prepared to take on the detection of hypertension?

Serrat-Costa M, Baltasar Bagué A, Machado Velasco R, Juvinyà Canal D, Bertran Noguer C, Ricart W.

Hipertens Riesgo Vasc. 2016 Oct - Dec;33(4):126-132. doi: 10.1016/j.hipert.2016.06.003. Epub 2016 Jul 18.

PMID:
27443260
29.

Hepatic iron content is independently associated with serum hepcidin levels in subjects with obesity.

Moreno-Navarrete JM, Moreno M, Puig J, Blasco G, Ortega F, Xifra G, Ricart W, Fernández-Real JM.

Clin Nutr. 2017 Oct;36(5):1434-1439. doi: 10.1016/j.clnu.2016.09.022. Epub 2016 Sep 29.

PMID:
27745814
30.

Genome-wide DNA methylation pattern in visceral adipose tissue differentiates insulin-resistant from insulin-sensitive obese subjects.

Crujeiras AB, Diaz-Lagares A, Moreno-Navarrete JM, Sandoval J, Hervas D, Gomez A, Ricart W, Casanueva FF, Esteller M, Fernandez-Real JM.

Transl Res. 2016 Dec;178:13-24.e5. doi: 10.1016/j.trsl.2016.07.002. Epub 2016 Jul 15.

31.

Genetic variations of the bitter taste receptor TAS2R38 are associated with obesity and impact on single immune traits.

Ortega FJ, Agüera Z, Sabater M, Moreno-Navarrete JM, Alonso-Ledesma I, Xifra G, Botas P, Delgado E, Jimenez-Murcia S, Fernández-García JC, Tinahones FJ, Baños RM, Botella C, de la Torre R, Frühbeck G, Rodrigüez A, Estivill X, Casanueva F, Ricart W, Fernández-Aranda F, Fernández-Real JM.

Mol Nutr Food Res. 2016 Jul;60(7):1673-83. doi: 10.1002/mnfr.201500804. Epub 2016 May 27.

PMID:
27059147
32.

Erratum: Obesity changes the human gut mycobiome.

Mar Rodríguez M, Pérez D, Javier Chaves F, Esteve E, Marin-Garcia P, Xifra G, Vendrell J, Jové M, Pamplona R, Ricart W, Portero-Otin M, Chacón MR, Fernández Real JM.

Sci Rep. 2016 Feb 24;6:21679. doi: 10.1038/srep21679. No abstract available.

33.

Metabolomics uncovers the role of adipose tissue PDXK in adipogenesis and systemic insulin sensitivity.

Moreno-Navarrete JM, Jove M, Ortega F, Xifra G, Ricart W, Obis È, Pamplona R, Portero-Otin M, Fernández-Real JM.

Diabetologia. 2016 Apr;59(4):822-32. doi: 10.1007/s00125-016-3863-1. Epub 2016 Feb 2.

PMID:
26831303
34.

Adipose tissue R2* signal is increased in subjects with obesity: A preliminary MRI study.

Fernández-Real JM, Blasco G, Puig J, Moreno M, Xifra G, Sánchez-Gonzalez J, Maria Alustiza J, Pedraza S, Ricart W, María Moreno-Navarrete J.

Obesity (Silver Spring). 2016 Feb;24(2):352-8. doi: 10.1002/oby.21347. Epub 2015 Dec 26.

35.

Obesity Is Associated With Gene Expression and Imaging Markers of Iron Accumulation in Skeletal Muscle.

Moreno-Navarrete JM, Blasco G, Xifra G, Karczewska-Kupczewska M, Stefanowicz M, Matulewicz N, Puig J, Ortega F, Ricart W, Straczkowski M, Fernández-Real JM.

J Clin Endocrinol Metab. 2016 Mar;101(3):1282-9. doi: 10.1210/jc.2015-3303. Epub 2016 Jan 14.

PMID:
26765579
36.

Thyroid Hormone Receptors Are Differentially Expressed in Granulosa and Cervical Cells of Infertile Women.

López Navarro E, Ortega FJ, Francisco-Busquets E, Sabater-Masdeu M, Álvarez-Castaño E, Ricart W, Fernández-Real JM.

Thyroid. 2016 Mar;26(3):466-73. doi: 10.1089/thy.2015.0416. Epub 2016 Feb 5.

PMID:
26715425
37.

CISD1 in association with obesity-associated dysfunctional adipogenesis in human visceral adipose tissue.

Moreno-Navarrete JM, Moreno M, Ortega F, Sabater M, Xifra G, Ricart W, Fernández-Real JM.

Obesity (Silver Spring). 2016 Jan;24(1):139-47. doi: 10.1002/oby.21334.

38.

Serum Ferritin Relates to Carotid Intima-Media Thickness in Offspring of Fathers With Higher Serum Ferritin Levels.

Prats-Puig A, Moreno M, Carreras-Badosa G, Bassols J, Ricart W, López-Bermejo A, Fernández-Real JM.

Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):174-80. doi: 10.1161/ATVBAHA.115.306396. Epub 2015 Nov 19.

PMID:
26586658
39.

Bariatric surgery acutely changes the expression of inflammatory and lipogenic genes in obese adipose tissue.

Ortega FJ, Vilallonga R, Xifra G, Sabater M, Ricart W, Fernández-Real JM.

Surg Obes Relat Dis. 2016 Feb;12(2):357-62. doi: 10.1016/j.soard.2015.08.498. Epub 2015 Aug 24.

PMID:
26525371
40.

Lean mass, and not fat mass, is an independent determinant of carotid intima media thickness in obese subjects.

Moreno M, Puig J, Moreno-Navarrete JM, Xifra G, Ortega F, Ricart W, Fernández-Real JM.

Atherosclerosis. 2015 Dec;243(2):493-8. doi: 10.1016/j.atherosclerosis.2015.09.012. Epub 2015 Sep 9.

PMID:
26520905
41.

Obesity changes the human gut mycobiome.

Mar Rodríguez M, Pérez D, Javier Chaves F, Esteve E, Marin-Garcia P, Xifra G, Vendrell J, Jové M, Pamplona R, Ricart W, Portero-Otin M, Chacón MR, Fernández Real JM.

Sci Rep. 2015 Oct 12;5:14600. doi: 10.1038/srep14600. Erratum in: Sci Rep. 2016;6:21679.

42.

Gut Microbiota Interacts With Brain Microstructure and Function.

Fernandez-Real JM, Serino M, Blasco G, Puig J, Daunis-i-Estadella J, Ricart W, Burcelin R, Fernández-Aranda F, Portero-Otin M.

J Clin Endocrinol Metab. 2015 Dec;100(12):4505-13. doi: 10.1210/jc.2015-3076. Epub 2015 Oct 7.

PMID:
26445114
43.

Lower serum osteocalcin concentrations are associated with brain microstructural changes and worse cognitive performance.

Puig J, Blasco G, Daunis-i-Estadella J, Moreno M, Molina X, Alberich-Bayarri A, Xifra G, Pedraza S, Ricart W, Fernández-Aranda F, Fernández-Real JM.

Clin Endocrinol (Oxf). 2016 May;84(5):756-63. doi: 10.1111/cen.12954. Epub 2015 Dec 14.

PMID:
26406918
44.

Circulating hepcidin in type 2 diabetes: A multivariate analysis and double blind evaluation of metformin effects.

Suárez-Ortegón MF, Moreno M, Arbeláez A, Xifra G, Mosquera M, Moreno-Navarrete JM, Aguilar-de Plata C, Esteve E, Ricart W, Fernández-Real JM.

Mol Nutr Food Res. 2015 Dec;59(12):2460-70. doi: 10.1002/mnfr.201500310. Epub 2015 Oct 20.

PMID:
26394887
45.

Surgery-Induced Weight Loss Is Associated With the Downregulation of Genes Targeted by MicroRNAs in Adipose Tissue.

Ortega FJ, Mercader JM, Moreno-Navarrete JM, Nonell L, Puigdecanet E, Rodriquez-Hermosa JI, Rovira O, Xifra G, Guerra E, Moreno M, Mayas D, Moreno-Castellanos N, Fernández-Formoso JA, Ricart W, Tinahones FJ, Torrents D, Malagón MM, Fernández-Real JM.

J Clin Endocrinol Metab. 2015 Nov;100(11):E1467-76. doi: 10.1210/jc.2015-2357. Epub 2015 Aug 7.

PMID:
26252355
46.

Lipopolysaccharide binding protein is an adipokine involved in the resilience of the mouse adipocyte to inflammation.

Moreno-Navarrete JM, Escoté X, Ortega F, Camps M, Ricart W, Zorzano A, Vendrell J, Vidal-Puig A, Fernández-Real JM.

Diabetologia. 2015 Oct;58(10):2424-34. doi: 10.1007/s00125-015-3692-7. Epub 2015 Jul 23.

PMID:
26201685
47.

Circulating profiling reveals the effect of a polyunsaturated fatty acid-enriched diet on common microRNAs.

Ortega FJ, Cardona-Alvarado MI, Mercader JM, Moreno-Navarrete JM, Moreno M, Sabater M, Fuentes-Batllevell N, Ramírez-Chávez E, Ricart W, Molina-Torres J, Pérez-Luque EL, Fernández-Real JM.

J Nutr Biochem. 2015 Oct;26(10):1095-101. doi: 10.1016/j.jnutbio.2015.05.001. Epub 2015 May 30.

PMID:
26092372
48.

Inflammation triggers specific microRNA profiles in human adipocytes and macrophages and in their supernatants.

Ortega FJ, Moreno M, Mercader JM, Moreno-Navarrete JM, Fuentes-Batllevell N, Sabater M, Ricart W, Fernández-Real JM.

Clin Epigenetics. 2015 Apr 24;7:49. doi: 10.1186/s13148-015-0083-3. eCollection 2015.

49.

Circulating irisin levels are positively associated with metabolic risk factors in sedentary subjects.

Moreno M, Moreno-Navarrete JM, Serrano M, Ortega F, Delgado E, Sanchez-Ragnarsson C, Valdés S, Botas P, Ricart W, Fernández-Real JM.

PLoS One. 2015 Apr 21;10(4):e0124100. doi: 10.1371/journal.pone.0124100. eCollection 2015.

50.

DBC1 is involved in adipocyte inflammation and is a possible marker of human adipose tissue senescence.

Moreno-Navarrete JM, Moreno M, Vidal M, Ortega F, Ricart W, Fernández-Real JM.

Obesity (Silver Spring). 2015 Mar;23(3):519-22. doi: 10.1002/oby.20999. Epub 2015 Feb 13.

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