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mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans.

Puelles VG, van der Wolde JW, Wanner N, Scheppach MW, Cullen-McEwen LA, Bork T, Lindenmeyer MT, Gernhold L, Wong MN, Braun F, Cohen CD, Kett MM, Kuppe C, Kramann R, Saritas T, van Roeyen CR, Moeller MJ, Tribolet L, Rebello R, Sun YB, Li J, Müller-Newen G, Hughson MD, Hoy WE, Person F, Wiech T, Ricardo SD, Kerr PG, Denton KM, Furic L, Huber TB, Nikolic-Paterson DJ, Bertram JF.

JCI Insight. 2019 Sep 19;4(18). pii: 99271. doi: 10.1172/jci.insight.99271.


The Use of Live Cell Imaging and Automated Image Analysis to Assist With Determining Optimal Parameters for Angiogenic Assay in vitro.

Huuskes BM, DeBuque RJ, Kerr PG, Samuel CS, Ricardo SD.

Front Cell Dev Biol. 2019 Apr 10;7:45. doi: 10.3389/fcell.2019.00045. eCollection 2019.


The Use of Targeted Next Generation Sequencing to Explore Candidate Regulators of TGF-β1's Impact on Kidney Cells.

Wang B, Ji G, Naeem H, Wang J, Kantharidis P, Powell D, Ricardo SD.

Front Physiol. 2018 Dec 10;9:1755. doi: 10.3389/fphys.2018.01755. eCollection 2018.


The use of hydrogels for cell-based treatment of chronic kidney disease.

McFetridge ML, Del Borgo MP, Aguilar MI, Ricardo SD.

Clin Sci (Lond). 2018 Sep 16;132(17):1977-1994. doi: 10.1042/CS20180434. Print 2018 Sep 14. Review.


Induced Pluripotent Stem Cell-Derived Podocyte-Like Cells as Models for Assessing Mechanisms Underlying Heritable Disease Phenotype: Initial Studies Using Two Alport Syndrome Patient Lines Indicate Impaired Potassium Channel Activity.

Haynes JM, Selby JN, Vandekolk TH, Abad IPL, Ho JK, Lieuw WL, Leach K, Savige J, Saini S, Fisher CL, Ricardo SD.

J Pharmacol Exp Ther. 2018 Nov;367(2):335-347. doi: 10.1124/jpet.118.250142. Epub 2018 Aug 13.


Mucins and Truncated O-Glycans Unveil Phenotypic Discrepancies between Serous Ovarian Cancer Cell Lines and Primary Tumours.

Coelho R, Marcos-Silva L, Mendes N, Pereira D, Brito C, Jacob F, Steentoft C, Mandel U, Clausen H, David L, Ricardo S.

Int J Mol Sci. 2018 Jul 13;19(7). pii: E2045. doi: 10.3390/ijms19072045.


The therapeutic effect of mesenchymal stem cells on pulmonary myeloid cells following neonatal hyperoxic lung injury in mice.

Al-Rubaie A, Wise AF, Sozo F, De Matteo R, Samuel CS, Harding R, Ricardo SD.

Respir Res. 2018 Jun 8;19(1):114. doi: 10.1186/s12931-018-0816-x.


Gene editing of stem cells for kidney disease modelling and therapeutic intervention.

Lau RW, Wang B, Ricardo SD.

Nephrology (Carlton). 2018 Nov;23(11):981-990. doi: 10.1111/nep.13410. Review.


Endothelial Progenitor Cells and Vascular Health in Dialysis Patients.

Huuskes BM, DeBuque RJ, Polkinghorne KR, Samuel CS, Kerr PG, Ricardo SD.

Kidney Int Rep. 2017 Sep 18;3(1):205-211. doi: 10.1016/j.ekir.2017.09.004. eCollection 2018 Jan. No abstract available.


Peritoneal dissemination of ovarian cancer: role of MUC16-mesothelin interaction and implications for treatment.

Coelho R, Marcos-Silva L, Ricardo S, Ponte F, Costa A, Lopes JM, David L.

Expert Rev Anticancer Ther. 2018 Feb;18(2):177-186. doi: 10.1080/14737140.2018.1418326. Epub 2017 Dec 21. Review.


The Chemical Chaperone, PBA, Reduces ER Stress and Autophagy and Increases Collagen IV α5 Expression in Cultured Fibroblasts From Men With X-Linked Alport Syndrome and Missense Mutations.

Wang D, Mohammad M, Wang Y, Tan R, Murray LS, Ricardo S, Dagher H, van Agtmael T, Savige J.

Kidney Int Rep. 2017 Mar 27;2(4):739-748. doi: 10.1016/j.ekir.2017.03.004. eCollection 2017 Jul.


Cell-Based Therapies for Tissue Fibrosis.

Lim R, Ricardo SD, Sievert W.

Front Pharmacol. 2017 Sep 22;8:633. doi: 10.3389/fphar.2017.00633. eCollection 2017. Review.


Effects of antenatal melatonin therapy on lung structure in growth-restricted newborn lambs.

Polglase GR, Barbuto J, Allison BJ, Yawno T, Sutherland AE, Malhotra A, Schulze KE, Wallace EM, Jenkin G, Ricardo SD, Miller SL.

J Appl Physiol (1985). 2017 Nov 1;123(5):1195-1203. doi: 10.1152/japplphysiol.00783.2016. Epub 2017 Aug 17.


Antitumoral activity of sesquiterpene lactone diacethylpiptocarphol in mice.

Alexandre Schefer F, Ricardo S, Zozula Blind CL, Luis P, de Oliveira Souza BL, Branco Filippin MF, Weber BM, Regina Orofino KM.

J Ethnopharmacol. 2017 Feb 23;198:262-267. doi: 10.1016/j.jep.2017.01.022. Epub 2017 Jan 15.


miR-378 reduces mesangial hypertrophy and kidney tubular fibrosis via MAPK signalling.

Wang B, Yao K, Wise AF, Lau R, Shen HH, Tesch GH, Ricardo SD.

Clin Sci (Lond). 2017 Mar 1;131(5):411-423. doi: 10.1042/CS20160571. Epub 2017 Jan 4.


A Mouse Intra-Intestinal Infusion Model and its Application to the Study of Nanoparticle Distribution.

Sadio A, Amaral AL, Nunes R, Ricardo S, Sarmento B, Almeida R, Tsukamoto H, das Neves J.

Front Physiol. 2016 Nov 29;7:579. eCollection 2016.


Serelaxin improves the therapeutic efficacy of RXFP1-expressing human amnion epithelial cells in experimental allergic airway disease.

Royce SG, Tominaga AM, Shen M, Patel KP, Huuskes BM, Lim R, Ricardo SD, Samuel CS.

Clin Sci (Lond). 2016 Dec 1;130(23):2151-2165. Epub 2016 Sep 19.


Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling.

Hakim S, Dyson JM, Feeney SJ, Davies EM, Sriratana A, Koenig MN, Plotnikova OV, Smyth IM, Ricardo SD, Hobbs RM, Mitchell CA.

Hum Mol Genet. 2016 Jun 1;25(11):2295-2313. Epub 2016 Apr 7.


Phenotype and influx kinetics of leukocytes and inflammatory cytokine production in kidney ischemia/reperfusion injury.

Williams TM, Wise AF, Layton DS, Ricardo SD.

Nephrology (Carlton). 2018 Jan;23(1):75-85. doi: 10.1111/nep.12941.


Effect of MUC1/β-catenin interaction on the tumorigenic capacity of pancreatic CD133+ cells.

Sousa AM, Rei M, Freitas R, Ricardo S, Caffrey T, David L, Almeida R, Hollingsworth MA, Santos-Silva F.

Oncol Lett. 2016 Sep;12(3):1811-1817. Epub 2016 Jul 20.


Renal cellular hypoxia in adenine-induced chronic kidney disease.

Fong D, Ullah MM, Lal JG, Abdelkader A, Ow CP, Hilliard LM, Ricardo SD, Kelly DJ, Evans RG.

Clin Exp Pharmacol Physiol. 2016 Oct;43(10):896-905. doi: 10.1111/1440-1681.12621.


Mucin carriers of TF in ovarian cancer.

Ricardo S, Marcos-Silva L, David L.

J Cancer Res Clin Oncol. 2016 Aug;142(8):1867-8. doi: 10.1007/s00432-016-2186-4. Epub 2016 Jun 8. No abstract available.


Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis.

Wang B, Yao K, Huuskes BM, Shen HH, Zhuang J, Godson C, Brennan EP, Wilkinson-Berka JL, Wise AF, Ricardo SD.

Mol Ther. 2016 Aug;24(7):1290-301. doi: 10.1038/mt.2016.90. Epub 2016 May 18.


Mucins MUC16 and MUC1 are major carriers of SLe(a) and SLe(x) in borderline and malignant serous ovarian tumors.

Ricardo S, Marcos-Silva L, Valente C, Coelho R, Gomes R, David L.

Virchows Arch. 2016 Jun;468(6):715-22. doi: 10.1007/s00428-016-1929-6. Epub 2016 Mar 22.


Prognostic significance of CD44v6, p63, podoplanin and MMP-9 in oral squamous cell carcinomas.

Monteiro LS, Delgado ML, Ricardo S, do Amaral B, Salazar F, Pacheco JJ, Lopes CA, Bousbaa H, Warnakulasuryia S.

Oral Dis. 2016 May;22(4):303-12. doi: 10.1111/odi.12442. Epub 2016 Mar 7.


FGF control of E-cadherin targeting in the Drosophila midgut impacts on primordial germ cell motility.

Parés G, Ricardo S.

J Cell Sci. 2016 Jan 15;129(2):354-66. doi: 10.1242/jcs.174284. Epub 2015 Nov 24.


Human mesenchymal stem cells alter the gene profile of monocytes from patients with Type 2 diabetes and end-stage renal disease.

Wise AF, Williams TM, Rudd S, Wells CA, Kerr PG, Ricardo SD.

Regen Med. 2016 Mar;11(2):145-58. doi: 10.2217/rme.15.74. Epub 2015 Nov 6.


Mesenchymal stem cells as novel micro-ribonucleic acid delivery vehicles in kidney disease.

Yao K, Ricardo SD.

Nephrology (Carlton). 2016 May;21(5):363-71. doi: 10.1111/nep.12643. Review.


Mesenchymal stem cells and serelaxin synergistically abrogate established airway fibrosis in an experimental model of chronic allergic airways disease.

Royce SG, Shen M, Patel KP, Huuskes BM, Ricardo SD, Samuel CS.

Stem Cell Res. 2015 Nov;15(3):495-505. doi: 10.1016/j.scr.2015.09.007. Epub 2015 Sep 25.


A novel monoclonal antibody to a defined peptide epitope in MUC16.

Marcos-Silva L, Ricardo S, Chen K, Blixt O, Arigi E, Pereira D, Høgdall E, Mandel U, Bennett EP, Vakhrushev SY, David L, Clausen H.

Glycobiology. 2015 Nov;25(11):1172-82. doi: 10.1093/glycob/cwv056. Epub 2015 Jul 22.


M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure.

Moore JP, Vinh A, Tuck KL, Sakkal S, Krishnan SM, Chan CT, Lieu M, Samuel CS, Diep H, Kemp-Harper BK, Tare M, Ricardo SD, Guzik TJ, Sobey CG, Drummond GR.

Am J Physiol Heart Circ Physiol. 2015 Sep;309(5):H906-17. doi: 10.1152/ajpheart.00821.2014. Epub 2015 Jun 12.


Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression.

Cohen-Dvashi H, Ben-Chetrit N, Russell R, Carvalho S, Lauriola M, Nisani S, Mancini M, Nataraj N, Kedmi M, Roth L, Köstler W, Zeisel A, Yitzhaky A, Zylberg J, Tarcic G, Eilam R, Wigelman Y, Will R, Lavi S, Porat Z, Wiemann S, Ricardo S, Schmitt F, Caldas C, Yarden Y.

EMBO Mol Med. 2015 Mar;7(3):299-314. doi: 10.15252/emmm.201404134.


Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours.

Ricardo S, Marcos-Silva L, Pereira D, Pinto R, Almeida R, Söderberg O, Mandel U, Clausen H, Felix A, Lunet N, David L.

Mol Oncol. 2015 Feb;9(2):503-12. doi: 10.1016/j.molonc.2014.10.005. Epub 2014 Oct 22.


Combination therapy of mesenchymal stem cells and serelaxin effectively attenuates renal fibrosis in obstructive nephropathy.

Huuskes BM, Wise AF, Cox AJ, Lim EX, Payne NL, Kelly DJ, Samuel CS, Ricardo SD.

FASEB J. 2015 Feb;29(2):540-53. doi: 10.1096/fj.14-254789. Epub 2014 Nov 13.


Differentiation reprogramming in gastric intestinal metaplasia and dysplasia: role of SOX2 and CDX2.

Camilo V, Garrido M, Valente P, Ricardo S, Amaral AL, Barros R, Chaves P, Carneiro F, David L, Almeida R.

Histopathology. 2015 Feb;66(3):343-50. doi: 10.1111/his.12544. Epub 2014 Nov 10.


The effect of CSF-1 administration on lung maturation in a mouse model of neonatal hyperoxia exposure.

Jones CV, Alikhan MA, O'Reilly M, Sozo F, Williams TM, Harding R, Jenkin G, Ricardo SD.

Respir Res. 2014 Sep 6;15:110. doi: 10.1186/s12931-014-0110-5.


EMMPRIN expression in oral squamous cell carcinomas: correlation with tumor proliferation and patient survival.

Monteiro LS, Delgado ML, Ricardo S, Garcez F, do Amaral B, Pacheco JJ, Lopes C, Bousbaa H.

Biomed Res Int. 2014;2014:905680. doi: 10.1155/2014/905680. Epub 2014 May 21.


Role of microRNA machinery in kidney fibrosis.

Wang B, Ricardo S.

Clin Exp Pharmacol Physiol. 2014 Aug;41(8):543-50. doi: 10.1111/1440-1681.12249. Review.


Human mesenchymal stem cells alter macrophage phenotype and promote regeneration via homing to the kidney following ischemia-reperfusion injury.

Wise AF, Williams TM, Kiewiet MB, Payne NL, Siatskas C, Samuel CS, Ricardo SD.

Am J Physiol Renal Physiol. 2014 May 15;306(10):F1222-35. doi: 10.1152/ajprenal.00675.2013. Epub 2014 Mar 12.


Establishing the flow cytometric assessment of myeloid cells in kidney ischemia/reperfusion injury.

Williams TM, Wise AF, Alikhan MA, Layton DS, Ricardo SD.

Cytometry A. 2014 Mar;85(3):256-67. doi: 10.1002/cyto.a.22420. Epub 2013 Nov 21.


Does a nephron deficit exacerbate the renal and cardiovascular effects of obesity?

Gurusinghe S, Brown RD, Cai X, Samuel CS, Ricardo SD, Thomas MC, Kett MM.

PLoS One. 2013 Sep 3;8(9):e73095. doi: 10.1371/journal.pone.0073095. eCollection 2013.


Macrophages and CSF-1: implications for development and beyond.

Jones CV, Ricardo SD.

Organogenesis. 2013 Oct 1;9(4):249-60. doi: 10.4161/org.25676. Epub 2013 Jul 29. Review.


Human kidney cell reprogramming: applications for disease modeling and personalized medicine.

O'Neill AC, Ricardo SD.

J Am Soc Nephrol. 2013 Sep;24(9):1347-56. doi: 10.1681/ASN.2012121199. Epub 2013 Aug 15. Review.


A flow cytometric method for the analysis of macrophages in the vascular wall.

Moore JP, Sakkal S, Bullen ML, Kemp-Harper BK, Ricardo SD, Sobey CG, Drummond GR.

J Immunol Methods. 2013 Oct 31;396(1-2):33-43. doi: 10.1016/j.jim.2013.07.009. Epub 2013 Aug 6.


Control of vertigo after intratympanic corticoid therapy for unilateral Ménière's disease: a comparison of weekly versus daily fixed protocols.

Martin Sanz E, Zschaeck C, Gonzalez M, Mato T, Rodrigañez L, Barona R, Sanz R.

Otol Neurotol. 2013 Oct;34(8):1429-33. doi: 10.1097/MAO.0b013e31828d655f. Erratum in: Otol Neurotol. 2013 Dec;34(9):1751. Christiane, Zschaeck Luzardo [corrected to Zschaeck, Christiane]; Manuel, Gonzalez Juliao [corrected to Gonzalez, Manuel]; Teresa, Mato Patino [corrected to Mato, Teresa]; Laura, Rodrigañez Riesco [corrected to Rodrigañez, Laura]; De Guzmán, Rafael Baro.


Phosphorylated mammalian target of rapamycin is associated with an adverse outcome in oral squamous cell carcinoma.

Monteiro LS, Delgado ML, Ricardo S, Garcez F, do Amaral B, Warnakulasuriya S, Lopes C.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 May;115(5):638-45. doi: 10.1016/j.oooo.2013.01.022.


M2 macrophage polarisation is associated with alveolar formation during postnatal lung development.

Jones CV, Williams TM, Walker KA, Dickinson H, Sakkal S, Rumballe BA, Little MH, Jenkin G, Ricardo SD.

Respir Res. 2013 Apr 5;14:41. doi: 10.1186/1465-9921-14-41.


A functional role of the extracellular domain of Crumbs in cell architecture and apicobasal polarity.

Letizia A, Ricardo S, Moussian B, Martín N, Llimargas M.

J Cell Sci. 2013 May 15;126(Pt 10):2157-63. doi: 10.1242/jcs.122382. Epub 2013 Mar 22.


Phosphorylated EGFR at tyrosine 1173 correlates with poor prognosis in oral squamous cell carcinomas.

Monteiro L, Ricardo S, Delgado M, Garcez F, do Amaral B, Lopes C.

Oral Dis. 2014 Mar;20(2):178-85. doi: 10.1111/odi.12087. Epub 2013 Mar 6.


Visualizing renal primary cilia.

Deane JA, Verghese E, Martelotto LG, Cain JE, Galtseva A, Rosenblum ND, Watkins DN, Ricardo SD.

Nephrology (Carlton). 2013 Mar;18(3):161-8. doi: 10.1111/nep.12022. Review.


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