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Items: 1 to 50 of 79

1.

Dose finding for new vaccines: The role for immunostimulation/immunodynamic modelling.

Rhodes SJ, Knight GM, Kirschner DE, White RG, Evans TG.

J Theor Biol. 2019 Mar 21;465:51-55. doi: 10.1016/j.jtbi.2019.01.017. Epub 2019 Jan 10.

2.

Using vaccine Immunostimulation/Immunodynamic modelling methods to inform vaccine dose decision-making.

Rhodes SJ, Guedj J, Fletcher HA, Lindenstrøm T, Scriba TJ, Evans TG, Knight GM, White RG.

NPJ Vaccines. 2018 Sep 17;3:36. doi: 10.1038/s41541-018-0075-3. eCollection 2018.

3.

Using Data from Macaques To Predict Gamma Interferon Responses after Mycobacterium bovis BCG Vaccination in Humans: a Proof-of-Concept Study of Immunostimulation/Immunodynamic Modeling Methods.

Rhodes SJ, Sarfas C, Knight GM, White A, Pathan AA, McShane H, Evans TG, Fletcher H, Sharpe S, White RG.

Clin Vaccine Immunol. 2017 Mar 6;24(3). pii: e00525-16. doi: 10.1128/CVI.00525-16. Print 2017 Mar.

4.

The TB vaccine H56+IC31 dose-response curve is peaked not saturating: Data generation for new mathematical modelling methods to inform vaccine dose decisions.

Rhodes SJ, Zelmer A, Knight GM, Prabowo SA, Stockdale L, Evans TG, Lindenstrøm T, White RG, Fletcher H.

Vaccine. 2016 Dec 7;34(50):6285-6291. doi: 10.1016/j.vaccine.2016.10.060. Epub 2016 Nov 2.

5.

Individual-level factors associated with variation in mycobacterial-specific immune response: Gender and previous BCG vaccination status.

Rhodes SJ, Knight GM, Fielding K, Scriba TJ, Pathan AA, McShane H, Fletcher H, White RG.

Tuberculosis (Edinb). 2016 Jan;96:37-43. doi: 10.1016/j.tube.2015.10.002. Epub 2015 Nov 11.

6.

Novel Lethal Form of Congenital Hypopituitarism Associated With the First Recessive LHX4 Mutation.

Gregory LC, Humayun KN, Turton JP, McCabe MJ, Rhodes SJ, Dattani MT.

J Clin Endocrinol Metab. 2015 Jun;100(6):2158-64. doi: 10.1210/jc.2014-4484. Epub 2015 Apr 14.

7.

Porcine sst1 can physically interact with other somatostatin receptors, and its expression is regulated by metabolic/inflammatory sensors.

Gahete MD, Durán-Prado M, Delgado-Niebla E, Garrido JJ, Rhodes SJ, García-Navarro S, Gracia-Navarro F, Malagón MM, Luque RM, Castaño JP.

Am J Physiol Endocrinol Metab. 2014 Mar 1;306(5):E483-93. doi: 10.1152/ajpendo.00587.2013. Epub 2013 Dec 24.

8.

The role of DNA methylation in regulation of the murine Lhx3 gene.

Malik RE, Rhodes SJ.

Gene. 2014 Jan 25;534(2):272-81. doi: 10.1016/j.gene.2013.10.045. Epub 2013 Oct 31.

9.

Cell-specific actions of a human LHX3 gene enhancer during pituitary and spinal cord development.

Park S, Mullen RD, Rhodes SJ.

Mol Endocrinol. 2013 Dec;27(12):2013-27. doi: 10.1210/me.2013-1161. Epub 2013 Oct 7.

10.

LHX3 interacts with inhibitor of histone acetyltransferase complex subunits LANP and TAF-1β to modulate pituitary gene regulation.

Hunter CS, Malik RE, Witzmann FA, Rhodes SJ.

PLoS One. 2013 Jul 4;8(7):e68898. doi: 10.1371/journal.pone.0068898. Print 2013.

11.

Developmental analysis and influence of genetic background on the Lhx3 W227ter mouse model of combined pituitary hormone deficiency disease.

Prince KL, Colvin SC, Park S, Lai X, Witzmann FA, Rhodes SJ.

Endocrinology. 2013 Feb;154(2):738-48. doi: 10.1210/en.2012-1790. Epub 2013 Jan 3.

12.

Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt protein.

Dong Y, Zhang L, Zhang S, Bai Y, Chen H, Sun X, Yong W, Li W, Colvin SC, Rhodes SJ, Shou W, Zhang ZY.

J Biol Chem. 2012 Sep 14;287(38):32172-9. doi: 10.1074/jbc.M112.393462. Epub 2012 Jul 12.

13.

The transcription factor encyclopedia.

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperrière D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, Héligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW.

Genome Biol. 2012;13(3):R24. doi: 10.1186/gb-2012-13-3-r24.

14.

Utility of fecal and serum anti-Saccharomyces cerevisiae antibodies in the diagnosis of Crohn's disease-like condition of the pouch.

Tang LY, Cai H, Navaneethan U, Boone JH, Rhodes SJ, Moore L, Rho H, de La Motte C, Queener E, Shen B.

Int J Colorectal Dis. 2012 Nov;27(11):1455-63. doi: 10.1007/s00384-012-1444-4. Epub 2012 Mar 20.

PMID:
22430887
15.

A recessive mutation resulting in a disabling amino acid substitution (T194R) in the LHX3 homeodomain causes combined pituitary hormone deficiency.

Bechtold-Dalla Pozza S, Hiedl S, Roeb J, Lohse P, Malik RE, Park S, Durán-Prado M, Rhodes SJ.

Horm Res Paediatr. 2012;77(1):41-51. doi: 10.1159/000335929. Epub 2012 Jan 26.

16.

A distal modular enhancer complex acts to control pituitary- and nervous system-specific expression of the LHX3 regulatory gene.

Mullen RD, Park S, Rhodes SJ.

Mol Endocrinol. 2012 Feb;26(2):308-19. doi: 10.1210/me.2011-1252. Epub 2011 Dec 22.

17.

Clostridium difficile prevalence rates in a large healthcare system stratified according to patient population, age, gender, and specimen consistency.

Boone JH, Goodykoontz M, Rhodes SJ, Price K, Smith J, Gearhart KN, Carman RJ, Kerkering TM, Wilkins TD, Lyerly DM.

Eur J Clin Microbiol Infect Dis. 2012 Jul;31(7):1551-9. doi: 10.1007/s10096-011-1477-6. Epub 2011 Dec 14.

PMID:
22167256
18.

The role of homeodomain transcription factors in heritable pituitary disease.

Prince KL, Walvoord EC, Rhodes SJ.

Nat Rev Endocrinol. 2011 Jul 26;7(12):727-37. doi: 10.1038/nrendo.2011.119. Review.

PMID:
21788968
19.

Model of pediatric pituitary hormone deficiency separates the endocrine and neural functions of the LHX3 transcription factor in vivo.

Colvin SC, Malik RE, Showalter AD, Sloop KW, Rhodes SJ.

Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):173-8. doi: 10.1073/pnas.1009501108. Epub 2010 Dec 13.

20.

BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression.

Sehgal R, Sheibani N, Rhodes SJ, Belecky Adams TL.

Dev Biol. 2009 Aug 15;332(2):429-43. doi: 10.1016/j.ydbio.2009.05.579. Epub 2009 Jun 6.

21.

LHX3 and LHX4 transcription factors in pituitary development and disease.

Colvin SC, Mullen RD, Pfaeffle RW, Rhodes SJ.

Pediatr Endocrinol Rev. 2009 Jan;6 Suppl 2:283-90. Review.

PMID:
19337183
22.

Molecular analysis of novel PROP1 mutations associated with combined pituitary hormone deficiency (CPHD).

Kelberman D, Turton JP, Woods KS, Mehta A, Al-Khawari M, Greening J, Swift PG, Otonkoski T, Rhodes SJ, Dattani MT.

Clin Endocrinol (Oxf). 2009 Jan;70(1):96-103. doi: 10.1111/j.1365-2265.2008.03326.x. Epub 2008 Jun 25.

PMID:
19128366
23.

Hormone signaling pathways: planes, trains, and automobiles...

Rhodes SJ.

Trends Endocrinol Metab. 1998 Oct 1;9(8):345-7.

PMID:
18406302
24.

Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies.

Pfaeffle RW, Hunter CS, Savage JJ, Duran-Prado M, Mullen RD, Neeb ZP, Eiholzer U, Hesse V, Haddad NG, Stobbe HM, Blum WF, Weigel JF, Rhodes SJ.

J Clin Endocrinol Metab. 2008 Mar;93(3):1062-71. Epub 2007 Dec 11.

25.

Mutations in the LHX3 gene cause dysregulation of pituitary and neural target genes that reflect patient phenotypes.

Savage JJ, Hunter CS, Clark-Sturm SL, Jacob TM, Pfaeffle RW, Rhodes SJ.

Gene. 2007 Oct 1;400(1-2):44-51. Epub 2007 Jun 7.

26.

Comparative genomics reveals functional transcriptional control sequences in the Prop1 gene.

Ward RD, Davis SW, Cho M, Esposito C, Lyons RH, Cheng JF, Rubin EM, Rhodes SJ, Raetzman LT, Smith TP, Camper SA.

Mamm Genome. 2007 Jul;18(6-7):521-37. Epub 2007 Jun 8.

27.

Four novel mutations of the LHX3 gene cause combined pituitary hormone deficiencies with or without limited neck rotation.

Pfaeffle RW, Savage JJ, Hunter CS, Palme C, Ahlmann M, Kumar P, Bellone J, Schoenau E, Korsch E, Brämswig JH, Stobbe HM, Blum WF, Rhodes SJ.

J Clin Endocrinol Metab. 2007 May;92(5):1909-19. Epub 2007 Feb 27.

PMID:
17327381
28.

Transgenic mice expressing LHX3 transcription factor isoforms in the pituitary: effects on the gonadotrope axis and sex-specific reproductive disease.

Savage JJ, Mullen RD, Sloop KW, Colvin SC, Camper SA, Franklin CL, Rhodes SJ.

J Cell Physiol. 2007 Jul;212(1):105-17.

30.

Roles of the LHX3 and LHX4 LIM-homeodomain factors in pituitary development.

Mullen RD, Colvin SC, Hunter CS, Savage JJ, Walvoord EC, Bhangoo AP, Ten S, Weigel J, Pfäffle RW, Rhodes SJ.

Mol Cell Endocrinol. 2007 Feb;265-266:190-5. Epub 2007 Jan 8. Review.

31.

Porcine somatostatin receptor 2 displays typical pharmacological sst2 features but unique dynamics of homodimerization and internalization.

Durán-Prado M, Bucharles C, Gonzalez BJ, Vázquez-Martínez R, Martínez-Fuentes AJ, García-Navarro S, Rhodes SJ, Vaudry H, Malagón MM, Castaño JP.

Endocrinology. 2007 Jan;148(1):411-21. Epub 2006 Oct 19.

PMID:
17053026
32.

The LIM-homeodomain proteins Isl-1 and Lhx3 act with steroidogenic factor 1 to enhance gonadotrope-specific activity of the gonadotropin-releasing hormone receptor gene promoter.

Granger A, Bleux C, Kottler ML, Rhodes SJ, Counis R, Laverrière JN.

Mol Endocrinol. 2006 Sep;20(9):2093-108. Epub 2006 Apr 13.

PMID:
16613990
33.

Clinical case seminar: a novel LHX3 mutation presenting as combined pituitary hormonal deficiency.

Bhangoo AP, Hunter CS, Savage JJ, Anhalt H, Pavlakis S, Walvoord EC, Ten S, Rhodes SJ.

J Clin Endocrinol Metab. 2006 Mar;91(3):747-53. Epub 2006 Jan 4.

PMID:
16394081
34.

Two promoters mediate transcription from the human LHX3 gene: involvement of nuclear factor I and specificity protein 1.

Yaden BC, Garcia M 3rd, Smith TP, Rhodes SJ.

Endocrinology. 2006 Jan;147(1):324-37. Epub 2005 Sep 22.

PMID:
16179410
35.

LIM-homeodomain genes in mammalian development and human disease.

Hunter CS, Rhodes SJ.

Mol Biol Rep. 2005 Jun;32(2):67-77. Review.

PMID:
16022279
36.

DNA recognition properties of the LHX3b LIM homeodomain transcription factor.

Yaden BC, Savage JJ, Hunter CS, Rhodes SJ.

Mol Biol Rep. 2005 Mar;32(1):1-6.

PMID:
15865204
37.

Two promoters control the mouse Nmp4/CIZ transcription factor gene.

Alvarez M, Shah R, Rhodes SJ, Bidwell JP.

Gene. 2005 Feb 28;347(1):43-54. Epub 2005 Jan 21.

PMID:
15716059
38.

Serine/threonine/tyrosine phosphorylation of the LHX3 LIM-homeodomain transcription factor.

Parker GE, West BE, Witzmann FA, Rhodes SJ.

J Cell Biochem. 2005 Jan 1;94(1):67-80.

PMID:
15517599
39.

Regulation of the follicle-stimulating hormone beta gene by the LHX3 LIM-homeodomain transcription factor.

West BE, Parker GE, Savage JJ, Kiratipranon P, Toomey KS, Beach LR, Colvin SC, Sloop KW, Rhodes SJ.

Endocrinology. 2004 Nov;145(11):4866-79. Epub 2004 Jul 22.

PMID:
15271874
40.

Conserved amino acid sequences confer nuclear localization upon the Prophet of Pit-1 pituitary transcription factor protein.

Guy JC, Hunter CS, Showalter AD, Smith TP, Charoonpatrapong K, Sloop KW, Bidwell JP, Rhodes SJ.

Gene. 2004 Jul 21;336(2):263-73.

PMID:
15246537
41.

Cloning and analysis of axolotl ISL2 and LHX2 LIM-homeodomain transcription factors.

Showalter AD, Yaden BC, Chernoff EA, Rhodes SJ.

Genesis. 2004 Mar;38(3):110-21.

PMID:
15048808
42.

Nmp4/CIZ regulation of matrix metalloproteinase 13 (MMP-13) response to parathyroid hormone in osteoblasts.

Shah R, Alvarez M, Jones DR, Torrungruang K, Watt AJ, Selvamurugan N, Partridge NC, Quinn CO, Pavalko FM, Rhodes SJ, Bidwell JP.

Am J Physiol Endocrinol Metab. 2004 Aug;287(2):E289-96. Epub 2004 Mar 16.

43.

Transcriptional control during mammalian anterior pituitary development.

Savage JJ, Yaden BC, Kiratipranon P, Rhodes SJ.

Gene. 2003 Nov 13;319:1-19. Review.

PMID:
14597167
44.

Severe short stature and endogenous growth hormone resistance in twin brothers without growth hormone gene mutations.

Walvoord EC, Sloop KW, Dwyer CJ, Rhodes SJ, Pescovitz OH.

Endocrine. 2003 Aug;21(3):289-95.

PMID:
14515015
45.

Context-dependent transcription: all politics is local.

Alvarez M, Rhodes SJ, Bidwell JP.

Gene. 2003 Aug 14;313:43-57. Review.

PMID:
12957376
46.

Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals.

Freking BA, Murphy SK, Wylie AA, Rhodes SJ, Keele JW, Leymaster KA, Jirtle RL, Smith TP.

Genome Res. 2002 Oct;12(10):1496-506.

47.

Genetic defects in the development and function of the anterior pituitary gland.

Cushman LJ, Showalter AD, Rhodes SJ.

Ann Med. 2002;34(3):179-91. Review.

PMID:
12173688
48.
49.

Involvement of the nuclear matrix in the control of skeletal genes: the NMP1 (YY1), NMP2 (Cbfa1), and NMP4 (Nmp4/CIZ) transcription factors.

Bidwell JP, Torrungruang K, Alvarez M, Rhodes SJ, Shah R, Jones DR, Charoonpatrapong K, Hock JM, Watt AJ.

Crit Rev Eukaryot Gene Expr. 2001;11(4):279-97. Review.

PMID:
12067068
50.

Osteoblast intracellular localization of Nmp4 proteins.

Torrungruang K, Shah R, Alvarez M, Bowen DK, Gerard R, Pavalko FM, Elmendorf JS, Charoonpatrapong K, Hock J, Rhodes SJ, Bidwell JP.

Bone. 2002 Jun;30(6):931-6.

PMID:
12052465

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