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Items: 1 to 50 of 65

1.

Multiple Signaling Pathways Contribute to the Thrombin-induced Secretory Phenotype in Vascular Smooth Muscle Cells.

Jeong JY, Son Y, Kim BY, Eo SK, Rhim BY, Kim K.

Korean J Physiol Pharmacol. 2015 Nov;19(6):549-55. doi: 10.4196/kjpp.2015.19.6.549. Epub 2015 Oct 16.

2.

Cilostazol Upregulates Autophagy via SIRT1 Activation: Reducing Amyloid-β Peptide and APP-CTFβ Levels in Neuronal Cells.

Lee HR, Shin HK, Park SY, Kim HY, Bae SS, Lee WS, Rhim BY, Hong KW, Kim CD.

PLoS One. 2015 Aug 5;10(8):e0134486. doi: 10.1371/journal.pone.0134486. eCollection 2015.

3.

FSL-1, a Toll-like Receptor 2/6 Agonist, Induces Expression of Interleukin-1α in the Presence of 27-hydroxycholesterol.

Heo W, Kim SM, Eo SK, Rhim BY, Kim K.

Korean J Physiol Pharmacol. 2014 Dec;18(6):475-80. doi: 10.4196/kjpp.2014.18.6.475. Epub 2014 Dec 30.

4.

7α-Hydroxycholesterol Elicits TLR6-Mediated Expression of IL-23 in Monocytic Cells.

Seo HC, Kim SM, Eo SK, Rhim BY, Kim K.

Biomol Ther (Seoul). 2015 Jan;23(1):84-9. doi: 10.4062/biomolther.2014.067. Epub 2015 Jan 1.

5.

Inhibition of HMGB1-induced angiogenesis by cilostazol via SIRT1 activation in synovial fibroblasts from rheumatoid arthritis.

Kim HY, Park SY, Lee SW, Lee HR, Lee WS, Rhim BY, Hong KW, Kim CD.

PLoS One. 2014 Aug 15;9(8):e104743. doi: 10.1371/journal.pone.0104743. eCollection 2014.

6.

Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β.

Lee HR, Shin HK, Park SY, Kim HY, Lee WS, Rhim BY, Hong KW, Kim CD.

J Neurosci Res. 2014 Nov;92(11):1581-90. doi: 10.1002/jnr.23421. Epub 2014 Jun 5.

PMID:
24903973
7.

Attenuation of β-amyloid-induced tauopathy via activation of CK2α/SIRT1: targeting for cilostazol.

Lee HR, Shin HK, Park SY, Kim HY, Lee WS, Rhim BY, Hong KW, Kim CD.

J Neurosci Res. 2014 Feb;92(2):206-17. doi: 10.1002/jnr.23310. Epub 2013 Nov 19.

PMID:
24254769
8.

The cholesterol-binding antibiotic nystatin induces expression of macrophage inflammatory protein-1 in macrophages.

Baek S, Kim SM, Lee SA, Rhim BY, Eo SK, Kim K.

Biomol Ther (Seoul). 2013 Jan;21(1):42-8. doi: 10.4062/biomolther.2012.082.

9.

RhoA/ROCK-dependent pathway is required for TLR2-mediated IL-23 production in human synovial macrophages: suppression by cilostazol.

Park SY, Lee SW, Lee WS, Rhim BY, Lee SJ, Kwon SM, Hong KW, Kim CD.

Biochem Pharmacol. 2013 Nov 1;86(9):1320-7. doi: 10.1016/j.bcp.2013.08.017. Epub 2013 Aug 22.

10.

Differential regulation of CC chemokine ligand 2 and CXCL8 by antifungal agent nystatin in macrophages.

Kim DH, Rhim BY, Eo SK, Kim K.

Biochem Biophys Res Commun. 2013 Aug 2;437(3):392-6. doi: 10.1016/j.bbrc.2013.06.087. Epub 2013 Jul 2.

PMID:
23831464
11.

Multiple Signaling Molecules are Involved in Expression of CCL2 and IL-1β in Response to FSL-1, a Toll-Like Receptor 6 Agonist, in Macrophages.

Won K, Kim SM, Lee SA, Rhim BY, Eo SK, Kim K.

Korean J Physiol Pharmacol. 2012 Dec;16(6):447-53. doi: 10.4196/kjpp.2012.16.6.447. Epub 2012 Dec 10.

12.

Suppression of PU.1-linked TLR4 expression by cilostazol with decrease of cytokine production in macrophages from patients with rheumatoid arthritis.

Park SY, Lee SW, Baek SH, Lee CW, Lee WS, Rhim BY, Hong KW, Kim CD.

Br J Pharmacol. 2013 Mar;168(6):1401-11. doi: 10.1111/bph.12021.

13.

Roles of 7-ketocholesterol on the homeostasis of intracellular cholesterol level.

Son Y, Kim K, Kim S, Lee SA, Jang H, Rhim BY.

J Cardiovasc Pharmacol. 2012 Aug;60(2):199-207. doi: 10.1097/FJC.0b013e31825c3ddc.

PMID:
22622234
14.

Protection by cilostazol against amyloid-β(1-40)-induced suppression of viability and neurite elongation through activation of CK2α in HT22 mouse hippocampal cells.

Lee HR, Park SY, Kim HY, Shin HK, Lee WS, Rhim BY, Hong KW, Kim CD.

J Neurosci Res. 2012 Aug;90(8):1566-76. doi: 10.1002/jnr.23037. Epub 2012 Mar 16.

PMID:
22422579
15.

Peptidoglycan enhances secretion of monocyte chemoattractants via multiple signaling pathways.

Lee SA, Kim SM, Son YH, Lee CW, Chung SW, Eo SK, Rhim BY, Kim K.

Biochem Biophys Res Commun. 2011 Apr 29;408(1):132-8. doi: 10.1016/j.bbrc.2011.03.136. Epub 2011 Apr 2.

PMID:
21463602
16.

Extracellular Nucleotides Can Induce Chemokine (C-C motif) Ligand 2 Expression in Human Vascular Smooth Muscle Cells.

Kim JI, Kim HY, Kim SM, Lee SA, Son YH, Eo SK, Rhim BY, Kim K.

Korean J Physiol Pharmacol. 2011 Feb;15(1):31-6. doi: 10.4196/kjpp.2011.15.1.31. Epub 2011 Feb 28.

17.

Cilostazol enhances integrin-dependent homing of progenitor cells by activation of cAMP-dependent protein kinase in synergy with Epac1.

Lee DH, Lee HR, Shin HK, Park SY, Hong KW, Kim EK, Bae SS, Lee WS, Rhim BY, Kim CD.

J Neurosci Res. 2011 May;89(5):650-60. doi: 10.1002/jnr.22558. Epub 2011 Feb 17.

PMID:
21337364
18.

Induction of heme oxygenase-1 expression by cilostazol contributes to its anti-inflammatory effects in J774 murine macrophages.

Park SY, Lee SW, Baek SH, Lee SJ, Lee WS, Rhim BY, Hong KW, Kim CD.

Immunol Lett. 2011 May;136(2):138-45. doi: 10.1016/j.imlet.2011.01.003. Epub 2011 Jan 20.

PMID:
21256160
19.

Cilostazol enhances neovascularization in the mouse hippocampus after transient forebrain ischemia.

Shin HK, Lee HR, Lee DH, Hong KW, Lee JH, Park SY, Lee SJ, Lee JS, Lee WS, Rhim BY, Kim CD.

J Neurosci Res. 2010 Aug 1;88(10):2228-38. doi: 10.1002/jnr.22376.

PMID:
20175201
20.

Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction.

Park SY, Lee SW, Shin HK, Chung WT, Lee WS, Rhim BY, Hong KW, Kim CD.

Arthritis Rheum. 2010 Mar;62(3):732-41. doi: 10.1002/art.27291.

21.

Angiotensin II-induced aortic ring constriction is mediated by phosphatidylinositol 3-kinase/L-type calcium channel signaling pathway.

Do KH, Kim MS, Kim JH, Rhim BY, Lee WS, Kim CD, Bae SS.

Exp Mol Med. 2009 Aug 31;41(8):569-76. doi: 10.3858/emm.2009.41.8.062.

22.

Cilostazol ameliorates metabolic abnormalities with suppression of proinflammatory markers in a db/db mouse model of type 2 diabetes via activation of peroxisome proliferator-activated receptor gamma transcription.

Park SY, Shin HK, Lee JH, Kim CD, Lee WS, Rhim BY, Hong KW.

J Pharmacol Exp Ther. 2009 May;329(2):571-9. doi: 10.1124/jpet.108.146456. Epub 2009 Feb 12.

PMID:
19221061
23.

Extracellular heat shock protein 90 induces interleukin-8 in vascular smooth muscle cells.

Chung SW, Lee JH, Choi KH, Park YC, Eo SK, Rhim BY, Kim K.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):444-9. doi: 10.1016/j.bbrc.2008.11.063. Epub 2008 Nov 24.

PMID:
19028451
24.

TLR-4 agonistic lipopolysaccharide upregulates interleukin-8 at the transcriptional and post-translational level in vascular smooth muscle cells.

Hong TJ, Ban JE, Choi KH, Son YH, Kim SM, Eo SK, Park HJ, Rhim BY, Kim K.

Vascul Pharmacol. 2009 Jan-Feb;50(1-2):34-9. doi: 10.1016/j.vph.2008.08.006. Epub 2008 Sep 13.

PMID:
18824136
25.

Roles of ERK and NF-kappaB in Interleukin-8 Expression in Response to Heat Shock Protein 22 in Vascular Smooth Muscle Cells.

Kang SH, Lee JH, Choi KH, Rhim BY, Kim K.

Korean J Physiol Pharmacol. 2008 Aug;12(4):171-6. doi: 10.4196/kjpp.2008.12.4.171. Epub 2008 Aug 31.

26.

Synergistic efficacy of concurrent treatment with cilostazol and probucol on the suppression of reactive oxygen species and inflammatory markers in cultured human coronary artery endothelial cells.

Park SY, Lee JH, Shin HK, Kim CD, Lee WS, Rhim BY, Shin YW, Hong KW.

Korean J Physiol Pharmacol. 2008 Aug;12(4):165-70. doi: 10.4196/kjpp.2008.12.4.165. Epub 2008 Aug 31.

27.

7-Ketocholesterol upregulates interleukin-6 via mechanisms that are distinct from those of tumor necrosis factor-alpha, in vascular smooth muscle cells.

Sung SC, Kim K, Lee KA, Choi KH, Kim SM, Son YH, Moon YS, Eo SK, Rhim BY.

J Vasc Res. 2009;46(1):36-44. doi: 10.1159/000135663. Epub 2008 May 31.

28.

Roles of MAPK and NF-kappaB in interleukin-6 induction by lipopolysaccharide in vascular smooth muscle cells.

Son YH, Jeong YT, Lee KA, Choi KH, Kim SM, Rhim BY, Kim K.

J Cardiovasc Pharmacol. 2008 Jan;51(1):71-7. doi: 10.1097/FJC.0b013e31815bd23d.

PMID:
18209571
29.

High glucose enhances MMP-2 production in adventitial fibroblasts via Akt1-dependent NF-kappaB pathway.

Lee SJ, Bae SS, Kim KH, Lee WS, Rhim BY, Hong KW, Kim CD.

FEBS Lett. 2007 Sep 4;581(22):4189-94. Epub 2007 Aug 3.

30.

Beneficial synergistic effects of concurrent treatment with cilostazol and probucol against focal cerebral ischemic injury in rats.

Park SY, Lee JH, Kim CD, Rhim BY, Hong KW, Lee WS.

Brain Res. 2007 Jul 9;1157:112-20. Epub 2007 Apr 25.

PMID:
17521620
31.

7-Ketocholesterol predisposes human aorta smooth muscle cells to Fas-mediated death.

Rho MC, Kim YK, Chang JS, Lee HS, Baek JA, Chung MY, Lee HC, Lee HW, Rhim BY, Reidy MA, Kim K.

J Mol Cell Cardiol. 2005 Nov;39(5):823-32. Epub 2005 Sep 29.

PMID:
16198370
32.

TNF-alpha activates death pathway in human aorta smooth muscle cell in the presence of 7-ketocholesterol.

Lee HS, Chang JS, Baek JA, Chung MY, Lee HC, Rhim BY, Sok DE, Rho MC, Kim YK, Kim K.

Biochem Biophys Res Commun. 2005 Aug 12;333(4):1093-9.

PMID:
15993097
33.

Cilostazol reduces atherosclerosis by inhibition of superoxide and tumor necrosis factor-alpha formation in low-density lipoprotein receptor-null mice fed high cholesterol.

Lee JH, Oh GT, Park SY, Choi JH, Park JG, Kim CD, Lee WS, Rhim BY, Shin YW, Hong KW.

J Pharmacol Exp Ther. 2005 May;313(2):502-9. Epub 2005 Feb 25.

PMID:
15734902
34.

Epitope mapping of Porphyromonas gingivalis heat-shock protein and human heat-shock protein in human atherosclerosis.

Choi JI, Chung SW, Kang HS, Rhim BY, Park YM, Kim US, Kim SJ.

J Dent Res. 2004 Dec;83(12):936-40.

PMID:
15557401
36.

Cilostazol prevents focal cerebral ischemic injury by enhancing casein kinase 2 phosphorylation and suppression of phosphatase and tensin homolog deleted from chromosome 10 phosphorylation in rats.

Lee JH, Kim KY, Lee YK, Park SY, Kim CD, Lee WS, Rhim BY, Hong KW.

J Pharmacol Exp Ther. 2004 Mar;308(3):896-903. Epub 2003 Nov 21.

PMID:
14634032
37.
38.
39.

Impairment of autoregulatory vasodilation by NAD(P)H oxidase-dependent superoxide generation during acute stage of subarachnoid hemorrhage in rat pial artery.

Shin HK, Lee JH, Kim KY, Kim CD, Lee WS, Rhim BY, Hong KW.

J Cereb Blood Flow Metab. 2002 Jul;22(7):869-77.

PMID:
12142572
40.

Establishment of Porphyromonas gingivalis heat-shock-protein-specific T-cell lines from atherosclerosis patients.

Choi JI, Chung SW, Kang HS, Rhim BY, Kim SJ, Kim SJ.

J Dent Res. 2002 May;81(5):344-8.

PMID:
12097449
41.

Vascular NADH oxidase is involved in impaired endothelium-dependent vasodilation in OLETF rats, a model of type 2 diabetes.

Kim YK, Lee MS, Son SM, Kim IJ, Lee WS, Rhim BY, Hong KW, Kim CD.

Diabetes. 2002 Feb;51(2):522-7.

42.

Restoration of vasodilation and CBF autoregulation by genistein in rat pial artery after brain injury.

Hong KW, Shin HK, Kim CD, Lee WS, Rhim BY.

Am J Physiol Heart Circ Physiol. 2001 Jul;281(1):H308-15.

43.

SKP-450 inhibits migration and DNA synthesis stimulated by oxidized low density lipoprotein in smooth muscle cells.

Kim HH, Yoo SE, Lee WS, Rhim BY, Hong KW.

Eur J Pharmacol. 1999 Nov 3;383(3):373-9.

PMID:
10594331
44.

Metabolism of cAMP to adenosine: role in vasodilation of rat pial artery in response to hypotension.

Hong KW, Shin HK, Kim HH, Choi JM, Rhim BY, Lee WS.

Am J Physiol. 1999 Feb;276(2):H376-82. doi: 10.1152/ajpheart.1999.276.2.H376.

PMID:
9950836
46.

Effect of rebamipide on liver damage and increased tumor necrosis factor in a rat model of endotoxin shock.

Hong KW, Kim KE, Rhim BY, Lee WS, Kim CD.

Dig Dis Sci. 1998 Sep;43(9 Suppl):154S-159S.

PMID:
9753243
47.

Decreased CGRP level with increased sensitivity to CGRP in the pial arteries of spontaneously hypertensive rats.

Hong KW, Yu SS, Shin YW, Kim CD, Rhim BY, Lee WS.

Life Sci. 1997;60(10):697-705.

PMID:
9064474
48.

Pharmacological coupling and functional role for CGRP receptors in the vasodilation of rat pial arterioles.

Hong KW, Yoo SE, Yu SS, Lee JY, Rhim BY.

Am J Physiol. 1996 Jan;270(1 Pt 2):H317-23.

PMID:
8769767
49.
50.

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