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Items: 1 to 50 of 52

1.

Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer.

Reichert M, Bakir B, Moreira L, Pitarresi JR, Feldmann K, Simon L, Suzuki K, Maddipati R, Rhim AD, Schlitter AM, Kriegsmann M, Weichert W, Wirth M, Schuck K, Schneider G, Saur D, Reynolds AB, Klein-Szanto AJ, Pehlivanoglu B, Memis B, Adsay NV, Rustgi AK.

Dev Cell. 2018 Jun 18;45(6):696-711.e8. doi: 10.1016/j.devcel.2018.05.025.

PMID:
29920275
2.

A randomized dose-response trial of aerobic exercise and health-related quality of life in colon cancer survivors.

Brown JC, Damjanov N, Courneya KS, Troxel AB, Zemel BS, Rickels MR, Ky B, Rhim AD, Rustgi AK, Schmitz KH.

Psychooncology. 2018 Apr;27(4):1221-1228. doi: 10.1002/pon.4655. Epub 2018 Feb 20.

PMID:
29388275
3.

Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice.

Kopp JL, Dubois CL, Schaeffer DF, Samani A, Taghizadeh F, Cowan RW, Rhim AD, Stiles BL, Valasek M, Sander M.

Gastroenterology. 2018 Apr;154(5):1509-1523.e5. doi: 10.1053/j.gastro.2017.12.007. Epub 2017 Dec 19.

PMID:
29273451
4.

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance.

Farrell AS, Joly MM, Allen-Petersen BL, Worth PJ, Lanciault C, Sauer D, Link J, Pelz C, Heiser LM, Morton JP, Muthalagu N, Hoffman MT, Manning SL, Pratt ED, Kendsersky ND, Egbukichi N, Amery TS, Thoma MC, Jenny ZP, Rhim AD, Murphy DJ, Sansom OJ, Crawford HC, Sheppard BC, Sears RC.

Nat Commun. 2017 Nov 23;8(1):1728. doi: 10.1038/s41467-017-01967-6.

5.

Dose-response effects of exercise on insulin among colon cancer survivors.

Brown JC, Rickels MR, Troxel AB, Zemel BS, Damjanov N, Ky B, Rhim AD, Rustgi AK, Courneya KS, Schmitz KH.

Endocr Relat Cancer. 2018 Jan;25(1):11-19. doi: 10.1530/ERC-17-0377. Epub 2017 Oct 10.

PMID:
29018055
6.

Dose-response effects of aerobic exercise on body composition among colon cancer survivors: a randomised controlled trial.

Brown JC, Zemel BS, Troxel AB, Rickels MR, Damjanov N, Ky B, Rhim AD, Rustgi AK, Courneya KS, Schmitz KH.

Br J Cancer. 2017 Nov 21;117(11):1614-1620. doi: 10.1038/bjc.2017.339. Epub 2017 Sep 21.

PMID:
28934762
7.

Ultrasensitive mutation detection identifies rare residual cells causing acute myelogenous leukemia relapse.

Parkin B, Londoño-Joshi A, Kang Q, Tewari M, Rhim AD, Malek SN.

J Clin Invest. 2017 Sep 1;127(9):3484-3495. doi: 10.1172/JCI91964. Epub 2017 Aug 21.

8.

Dose-response Effects of Aerobic Exercise Among Colon Cancer Survivors: A Randomized Phase II Trial.

Brown JC, Troxel AB, Ky B, Damjanov N, Zemel BS, Rickels MR, Rhim AD, Rustgi AK, Courneya KS, Schmitz KH.

Clin Colorectal Cancer. 2018 Mar;17(1):32-40. doi: 10.1016/j.clcc.2017.06.001. Epub 2017 Jun 17.

PMID:
28669606
9.

3rd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of pancreatic cancer.

Lutz MP, Zalcberg JR, Ducreux M, Aust D, Bruno MJ, Büchler MW, Delpero JR, Gloor B, Glynne-Jones R, Hartwig W, Huguet F, Laurent-Puig P, Lordick F, Maisonneuve P, Mayerle J, Martignoni M, Neoptolemos J, Rhim AD, Schmied BM, Seufferlein T, Werner J, van Laethem JL, Otto F.

Eur J Cancer. 2017 Jul;79:41-49. doi: 10.1016/j.ejca.2017.03.022. Epub 2017 Apr 29.

10.

Lactulose Is Associated With Decreased Risk of Clostridium difficile Infection in Decompensated Cirrhosis.

Agarwalla A, Weber A, Davey S, Hamilton K, Goldberg D, Rhim AD, Yang YX.

Clin Gastroenterol Hepatol. 2017 Jun;15(6):953-954. doi: 10.1016/j.cgh.2017.01.012. Epub 2017 Jan 23. No abstract available.

PMID:
28126426
11.

A Clinical Prediction Model to Assess Risk for Pancreatic Cancer Among Patients With New-Onset Diabetes.

Boursi B, Finkelman B, Giantonio BJ, Haynes K, Rustgi AK, Rhim AD, Mamtani R, Yang YX.

Gastroenterology. 2017 Mar;152(4):840-850.e3. doi: 10.1053/j.gastro.2016.11.046. Epub 2016 Dec 5.

12.

Can Stopping Nerves, Stop Cancer?

Saloman JL, Albers KM, Rhim AD, Davis BM.

Trends Neurosci. 2016 Dec;39(12):880-889. doi: 10.1016/j.tins.2016.10.002. Epub 2016 Nov 8. Review.

13.

Adipocytes promote pancreatic cancer cell proliferation via glutamine transfer.

Meyer KA, Neeley CK, Baker NA, Washabaugh AR, Flesher CG, Nelson BS, Frankel TL, Lumeng CN, Lyssiotis CA, Wynn ML, Rhim AD, O'Rourke RW.

Biochem Biophys Rep. 2016 Sep;7:144-149. Epub 2016 Jun 7.

14.

Pancreatic Cancer Chemoprevention Translational Workshop: Meeting Report.

Miller MS, Allen P, Brentnall TA, Goggins M, Hruban RH, Petersen GM, Rao CV, Whitcomb DC, Brand RE, Chari ST, Klein AP, Lubman DM, Rhim AD, Simeone DM, Wolpin BM, Umar A, Srivastava S, Steele VE, Rinaudo JA.

Pancreas. 2016 Sep;45(8):1080-91. doi: 10.1097/MPA.0000000000000705.

15.

Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer.

Zhang Y, Velez-Delgado A, Mathew E, Li D, Mendez FM, Flannagan K, Rhim AD, Simeone DM, Beatty GL, Pasca di Magliano M.

Gut. 2017 Jan;66(1):124-136. doi: 10.1136/gutjnl-2016-312078. Epub 2016 Jul 8.

16.

A randomized phase II dose-response exercise trial among colon cancer survivors: Purpose, study design, methods, and recruitment results.

Brown JC, Troxel AB, Ky B, Damjanov N, Zemel BS, Rickels MR, Rhim AD, Rustgi AK, Courneya KS, Schmitz KH.

Contemp Clin Trials. 2016 Mar;47:366-75. doi: 10.1016/j.cct.2016.03.001. Epub 2016 Mar 10.

17.

Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer.

Saloman JL, Albers KM, Li D, Hartman DJ, Crawford HC, Muha EA, Rhim AD, Davis BM.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3078-83. doi: 10.1073/pnas.1512603113. Epub 2016 Feb 29.

18.

Orthotopic Injection of Pancreatic Cancer Cells.

Aiello NM, Rhim AD, Stanger BZ.

Cold Spring Harb Protoc. 2016 Jan 4;2016(1):pdb.prot078360. doi: 10.1101/pdb.prot078360.

PMID:
26729902
19.

Isolating Epithelial and Epithelial-to-Mesenchymal Transition Populations from Primary Tumors by Fluorescence-Activated Cell Sorting.

Aiello NM, Rhim AD, Stanger BZ.

Cold Spring Harb Protoc. 2016 Jan 4;2016(1):pdb.prot078352. doi: 10.1101/pdb.prot078352.

PMID:
26729901
20.

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.

Roberts NJ, Norris AL, Petersen GM, Bondy ML, Brand R, Gallinger S, Kurtz RC, Olson SH, Rustgi AK, Schwartz AG, Stoffel E, Syngal S, Zogopoulos G, Ali SZ, Axilbund J, Chaffee KG, Chen YC, Cote ML, Childs EJ, Douville C, Goes FS, Herman JM, Iacobuzio-Donahue C, Kramer M, Makohon-Moore A, McCombie RW, McMahon KW, Niknafs N, Parla J, Pirooznia M, Potash JB, Rhim AD, Smith AL, Wang Y, Wolfgang CL, Wood LD, Zandi PP, Goggins M, Karchin R, Eshleman JR, Papadopoulos N, Kinzler KW, Vogelstein B, Hruban RH, Klein AP.

Cancer Discov. 2016 Feb;6(2):166-75. doi: 10.1158/2159-8290.CD-15-0402. Epub 2015 Dec 9.

21.

A New Scalpel for the Treatment of Pancreatic Cancer: Targeting Stromal-Derived STAT3 Signaling.

Cowan RW, Maitra A, Rhim AD.

Gastroenterology. 2015 Dec;149(7):1685-8. doi: 10.1053/j.gastro.2015.10.028. Epub 2015 Oct 23. No abstract available.

22.

Culturing mouse tumor cells.

Rhim AD, Jechlinger M, Rustgi AK.

Cold Spring Harb Protoc. 2015 Jun 1;2015(6):505-7. doi: 10.1101/pdb.top069989. Review.

PMID:
26034311
23.

Culturing primary mouse pancreatic ductal cells.

Reichert M, Rhim AD, Rustgi AK.

Cold Spring Harb Protoc. 2015 Jun 1;2015(6):558-61. doi: 10.1101/pdb.prot078279.

PMID:
26034301
24.

Creation of primary cell lines from lineage-labeled mouse models of cancer.

Rhim AD.

Cold Spring Harb Protoc. 2015 May 1;2015(5):453-6. doi: 10.1101/pdb.prot078287.

25.

Early detection of sporadic pancreatic cancer: summative review.

Chari ST, Kelly K, Hollingsworth MA, Thayer SP, Ahlquist DA, Andersen DK, Batra SK, Brentnall TA, Canto M, Cleeter DF, Firpo MA, Gambhir SS, Go VL, Hines OJ, Kenner BJ, Klimstra DS, Lerch MM, Levy MJ, Maitra A, Mulvihill SJ, Petersen GM, Rhim AD, Simeone DM, Srivastava S, Tanaka M, Vinik AI, Wong D.

Pancreas. 2015 Jul;44(5):693-712. doi: 10.1097/MPA.0000000000000368. Review.

26.

Three-dimensional organotypic culture of stratified epithelia.

Rhim AD, Rustgi AK.

Cold Spring Harb Protoc. 2015 Apr 1;2015(4):349-53. doi: 10.1101/pdb.prot078311.

27.

ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis.

Wang L, Yang H, Abel EV, Ney GM, Palmbos PL, Bednar F, Zhang Y, Leflein J, Waghray M, Owens S, Wilkinson JE, Prasad J, Ljungman M, Rhim AD, Pasca di Magliano M, Simeone DM.

Genes Dev. 2015 Jan 15;29(2):171-83. doi: 10.1101/gad.253591.114.

28.

Characterization of microfluidic shear-dependent epithelial cell adhesion molecule immunocapture and enrichment of pancreatic cancer cells from blood cells with dielectrophoresis.

Huang C, Smith JP, Saha TN, Rhim AD, Kirby BJ.

Biomicrofluidics. 2014 Jul 21;8(4):044107. doi: 10.1063/1.4890466. eCollection 2014 Jul.

29.

Polarization of the vacuolar adenosine triphosphatase delineates a transition to high-grade pancreatic intraepithelial neoplasm lesions.

Sreekumar BK, Belinsky GS, Einwachter H, Rhim AD, Schmid R, Chung C.

Pancreas. 2014 Nov;43(8):1256-63. doi: 10.1097/MPA.0000000000000201.

30.

Molecular biology of pancreatic ductal adenocarcinoma.

Coleman SJ, Rhim AD.

Curr Opin Gastroenterol. 2014 Sep;30(5):506-10. doi: 10.1097/MOG.0000000000000104. Review.

PMID:
25023382
31.

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.

Rhim AD, Oberstein PE, Thomas DH, Mirek ET, Palermo CF, Sastra SA, Dekleva EN, Saunders T, Becerra CP, Tattersall IW, Westphalen CB, Kitajewski J, Fernandez-Barrena MG, Fernandez-Zapico ME, Iacobuzio-Donahue C, Olive KP, Stanger BZ.

Cancer Cell. 2014 Jun 16;25(6):735-47. doi: 10.1016/j.ccr.2014.04.021. Epub 2014 May 22.

32.

Microfluidic immunocapture of circulating pancreatic cells using parallel EpCAM and MUC1 capture: characterization, optimization and downstream analysis.

Thege FI, Lannin TB, Saha TN, Tsai S, Kochman ML, Hollingsworth MA, Rhim AD, Kirby BJ.

Lab Chip. 2014 May 21;14(10):1775-84. doi: 10.1039/c4lc00041b. Epub 2014 Mar 28.

PMID:
24681997
33.

Diagnosis of pernicious anemia and the risk of pancreatic cancer.

Shah P, Rhim AD, Haynes K, Hwang WT, Yang YX.

Pancreas. 2014 Apr;43(3):422-6. doi: 10.1097/MPA.0000000000000054.

34.

Neuroplastic changes occur early in the development of pancreatic ductal adenocarcinoma.

Stopczynski RE, Normolle DP, Hartman DJ, Ying H, DeBerry JJ, Bielefeldt K, Rhim AD, DePinho RA, Albers KM, Davis BM.

Cancer Res. 2014 Mar 15;74(6):1718-27. doi: 10.1158/0008-5472.CAN-13-2050. Epub 2014 Jan 21.

35.

Detection of circulating pancreas epithelial cells in patients with pancreatic cystic lesions.

Rhim AD, Thege FI, Santana SM, Lannin TB, Saha TN, Tsai S, Maggs LR, Kochman ML, Ginsberg GG, Lieb JG, Chandrasekhara V, Drebin JA, Ahmad N, Yang YX, Kirby BJ, Stanger BZ.

Gastroenterology. 2014 Mar;146(3):647-51. doi: 10.1053/j.gastro.2013.12.007. Epub 2013 Dec 13.

36.

The effects of long-term therapy with proton pump inhibitors on meal stimulated gastrin.

Helgadóttir H, Metz DC, Yang YX, Rhim AD, Björnsson ES.

Dig Liver Dis. 2014 Feb;46(2):125-30. doi: 10.1016/j.dld.2013.09.021. Epub 2013 Nov 6.

PMID:
24210828
37.

Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.

Zhang Y, Yan W, Collins MA, Bednar F, Rakshit S, Zetter BR, Stanger BZ, Chung I, Rhim AD, di Magliano MP.

Cancer Res. 2013 Oct 15;73(20):6359-74. doi: 10.1158/0008-5472.CAN-13-1558-T. Epub 2013 Oct 4.

38.

An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression.

Kim J, Hoffman JP, Alpaugh RK, Rhim AD, Reichert M, Stanger BZ, Furth EE, Sepulveda AR, Yuan CX, Won KJ, Donahue G, Sands J, Gumbs AA, Zaret KS.

Cell Rep. 2013 Jun 27;3(6):2088-99. doi: 10.1016/j.celrep.2013.05.036. Epub 2013 Jun 20. Erratum in: Cell Rep. 2013 Jul 25;4(2):403. Rhimm, Andrew D [corrected to Rhim, Andrew D].

39.

IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts.

Hamilton KE, Noubissi FK, Katti PS, Hahn CM, Davey SR, Lundsmith ET, Klein-Szanto AJ, Rhim AD, Spiegelman VS, Rustgi AK.

Carcinogenesis. 2013 Nov;34(11):2647-54. doi: 10.1093/carcin/bgt217. Epub 2013 Jun 12.

40.

Epithelial to mesenchymal transition and the generation of stem-like cells in pancreatic cancer.

Rhim AD.

Pancreatology. 2013 Mar-Apr;13(2):114-7. doi: 10.1016/j.pan.2013.01.004. Epub 2013 Jan 22. Review.

41.

The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.

Reichert M, Takano S, von Burstin J, Kim SB, Lee JS, Ihida-Stansbury K, Hahn C, Heeg S, Schneider G, Rhim AD, Stanger BZ, Rustgi AK.

Genes Dev. 2013 Feb 1;27(3):288-300. doi: 10.1101/gad.204453.112. Epub 2013 Jan 25.

42.

Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer.

Bayne LJ, Beatty GL, Jhala N, Clark CE, Rhim AD, Stanger BZ, Vonderheide RH.

Cancer Cell. 2012 Jun 12;21(6):822-35. doi: 10.1016/j.ccr.2012.04.025.

43.

EMT and dissemination precede pancreatic tumor formation.

Rhim AD, Mirek ET, Aiello NM, Maitra A, Bailey JM, McAllister F, Reichert M, Beatty GL, Rustgi AK, Vonderheide RH, Leach SD, Stanger BZ.

Cell. 2012 Jan 20;148(1-2):349-61. doi: 10.1016/j.cell.2011.11.025.

44.

Molecular biology of pancreatic ductal adenocarcinoma progression: aberrant activation of developmental pathways.

Rhim AD, Stanger BZ.

Prog Mol Biol Transl Sci. 2010;97:41-78. doi: 10.1016/B978-0-12-385233-5.00002-7. Review.

45.
46.

Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma.

Plentz R, Park JS, Rhim AD, Abravanel D, Hezel AF, Sharma SV, Gurumurthy S, Deshpande V, Kenific C, Settleman J, Majumder PK, Stanger BZ, Bardeesy N.

Gastroenterology. 2009 May;136(5):1741-9.e6. doi: 10.1053/j.gastro.2009.01.008. Epub 2009 Jan 14.

47.

A young woman with gallstone pancreatitis and abnormal liver tests: when is endoscopic retrograde cholangiopancreatography needed?

Rhim AD, Kochman ML.

Clin Gastroenterol Hepatol. 2008 Jul;6(7):741-5. doi: 10.1016/j.cgh.2008.02.059. Epub 2008 Jun 10. No abstract available.

48.

The effect of anti-TNF-alpha therapy on spinal bone mineral density in patients with Crohn's disease.

Pazianas M, Rhim AD, Weinberg AM, Su C, Lichtenstein GR.

Ann N Y Acad Sci. 2006 Apr;1068:543-56.

PMID:
16831950
49.

Severity of liver disease does not predict osteopenia or low bone mineral density in primary sclerosing cholangitis.

Campbell MS, Lichtenstein GR, Rhim AD, Pazianas M, Faust T.

Liver Int. 2005 Apr;25(2):311-6.

PMID:
15780055
50.

Altered terminal glycosylation and the pathophysiology of CF lung disease.

Rhim AD, Stoykova LI, Trindade AJ, Glick MC, Scanlin TF.

J Cyst Fibros. 2004 Aug;3 Suppl 2:95-6.

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