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Items: 1 to 50 of 345

1.

Peroxiredoxin-mediated disulfide bond formation is required for nucleocytoplasmic translocation and secretion of HMGB1 in response to inflammatory stimuli.

Kwak MS, Kim HS, Lkhamsuren K, Kim YH, Han MG, Shin JM, Park IH, Rhee WJ, Lee SK, Rhee SG, Shin JS.

Redox Biol. 2019 Jun;24:101203. doi: 10.1016/j.redox.2019.101203. Epub 2019 Apr 15.

3.

Inactivation of the PtdIns(4)P phosphatase Sac1 at the Golgi by H2O2 produced via Ca2+-dependent Duox in EGF-stimulated cells.

Park S, Lim JM, Park SH, Kim S, Heo S, Balla T, Jeong W, Rhee SG, Kang D.

Free Radic Biol Med. 2019 Feb 1;131:40-49. doi: 10.1016/j.freeradbiomed.2018.11.021. Epub 2018 Nov 23.

PMID:
30476538
4.

Accumulation of PtdIns(4)P at the Golgi mediated by reversible oxidation of the PtdIns(4)P phosphatase Sac1 by H2O2.

Lim JM, Park S, Lee MS, Balla T, Kang D, Rhee SG.

Free Radic Biol Med. 2019 Jan;130:426-435. doi: 10.1016/j.freeradbiomed.2018.11.008. Epub 2018 Nov 16.

PMID:
30448513
5.

Peroxiredoxin5 Controls Vertebrate Ciliogenesis by Modulating Mitochondrial Reactive Oxygen Species.

Ji Y, Chae S, Lee HK, Park I, Kim C, Ismail T, Kim Y, Park JW, Kwon OS, Kang BS, Lee DS, Bae JS, Kim SH, Moon PG, Baek MC, Park MJ, Kil IS, Rhee SG, Kim J, Huh YH, Shin JY, Min KJ, Kwon TK, Jang DG, Woo HA, Kwon T, Park TJ, Lee HS.

Antioxid Redox Signal. 2019 May 10;30(14):1731-1745. doi: 10.1089/ars.2018.7507. Epub 2018 Oct 30.

PMID:
30191719
6.

Enhanced Phosphorylation of Bax and Its Translocation into Mitochondria in the Brains of Individuals Affiliated with Alzheimer's Disease.

Henderson LE, Abdelmegeed MA, Yoo SH, Rhee SG, Zhu X, Smith MA, Nguyen RQ, Perry G, Song BJ.

Open Neurol J. 2017 Nov 16;11:48-58. doi: 10.2174/1874205X01711010048. eCollection 2017.

7.

Cellular Timekeeping: It's Redox o'Clock.

Milev NB, Rhee SG, Reddy AB.

Cold Spring Harb Perspect Biol. 2018 May 1;10(5). pii: a027698. doi: 10.1101/cshperspect.a027698. Review.

PMID:
28778867
8.

The Role of Peroxiredoxins in the Transduction of H2O2 Signals.

Rhee SG, Woo HA, Kang D.

Antioxid Redox Signal. 2018 Mar 1;28(7):537-557. doi: 10.1089/ars.2017.7167. Epub 2017 Jul 10. Review.

PMID:
28587524
9.

Mitochondrial H2O2 signaling is controlled by the concerted action of peroxiredoxin III and sulfiredoxin: Linking mitochondrial function to circadian rhythm.

Rhee SG, Kil IS.

Free Radic Biol Med. 2016 Nov;100:73-80. doi: 10.1016/j.freeradbiomed.2016.10.011. Epub 2016 Oct 27. Review.

PMID:
28236420
10.

Multiple Functions and Regulation of Mammalian Peroxiredoxins.

Rhee SG, Kil IS.

Annu Rev Biochem. 2017 Jun 20;86:749-775. doi: 10.1146/annurev-biochem-060815-014431. Epub 2017 Feb 2. Review.

PMID:
28226215
11.

p62/SQSTM1 is required for the protection against endoplasmic reticulum stress-induced apoptotic cell death.

Park JS, Oh SY, Lee DH, Lee YS, Sung SH, Ji HW, Lee MJ, Lee YH, Rhee SG, Bae SH.

Free Radic Res. 2016 Dec;50(12):1408-1421. Epub 2016 Nov 23.

PMID:
27780373
12.

Mitochondrial H2O2 signaling is controlled by the concerted action of peroxiredoxin III and sulfiredoxin: Linking mitochondrial function to circadian rhythm.

Rhee SG, Kil IS.

Free Radic Biol Med. 2016 Aug 4;99:120-127. doi: 10.1016/j.freeradbiomed.2016.07.029. [Epub ahead of print] Review.

PMID:
27497909
13.

SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages.

Kim MJ, Bae SH, Ryu JC, Kwon Y, Oh JH, Kwon J, Moon JS, Kim K, Miyawaki A, Lee MG, Shin J, Kim YS, Kim CH, Ryter SW, Choi AM, Rhee SG, Ryu JH, Yoon JH.

Autophagy. 2016 Aug 2;12(8):1272-91. doi: 10.1080/15548627.2016.1183081. Epub 2016 Jun 23.

14.

Overview on Peroxiredoxin.

Rhee SG.

Mol Cells. 2016 Jan;39(1):1-5. doi: 10.14348/molcells.2016.2368. Review.

15.

Sulfiredoxin inhibitor induces preferential death of cancer cells through reactive oxygen species-mediated mitochondrial damage.

Kim H, Lee GR, Kim J, Baek JY, Jo YJ, Hong SE, Kim SH, Lee J, Lee HI, Park SK, Kim HM, Lee HJ, Chang TS, Rhee SG, Lee JS, Jeong W.

Free Radic Biol Med. 2016 Feb;91:264-74. doi: 10.1016/j.freeradbiomed.2015.12.023. Epub 2015 Dec 23.

PMID:
26721593
16.

Effective Killing of Cancer Cells Through ROS-Mediated Mechanisms by AMRI-59 Targeting Peroxiredoxin I.

Yang YJ, Baek JY, Goo J, Shin Y, Park JK, Jang JY, Wang SB, Jeong W, Lee HJ, Um HD, Lee SK, Choi Y, Rhee SG, Chang TS.

Antioxid Redox Signal. 2016 Mar 10;24(8):453-69. doi: 10.1089/ars.2014.6187. Epub 2015 Dec 18.

PMID:
26528922
17.

Circadian Oscillation of Sulfiredoxin in the Mitochondria.

Kil IS, Ryu KW, Lee SK, Kim JY, Chu SY, Kim JH, Park S, Rhee SG.

Mol Cell. 2015 Aug 20;59(4):651-63. doi: 10.1016/j.molcel.2015.06.031. Epub 2015 Jul 30.

18.

Control of the pericentrosomal H2O2 level by peroxiredoxin I is critical for mitotic progression.

Lim JM, Lee KS, Woo HA, Kang D, Rhee SG.

J Cell Biol. 2015 Jul 6;210(1):23-33. doi: 10.1083/jcb.201412068.

19.

The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1.

Rhee SG, Bae SH.

Free Radic Biol Med. 2015 Nov;88(Pt B):205-211. doi: 10.1016/j.freeradbiomed.2015.06.007. Epub 2015 Jun 25. Review.

PMID:
26117317
20.

Peroxiredoxin 3 has a crucial role in the contractile function of skeletal muscle by regulating mitochondrial homeostasis.

Lee KP, Shin YJ, Cho SC, Lee SM, Bahn YJ, Kim JY, Kwon ES, Jeong DY, Park SC, Rhee SG, Woo HA, Kwon KS.

Free Radic Biol Med. 2014 Dec;77:298-306. doi: 10.1016/j.freeradbiomed.2014.09.010. Epub 2014 Sep 16.

PMID:
25224038
21.

Circadian rhythm of hyperoxidized peroxiredoxin II is determined by hemoglobin autoxidation and the 20S proteasome in red blood cells.

Cho CS, Yoon HJ, Kim JY, Woo HA, Rhee SG.

Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12043-8. doi: 10.1073/pnas.1401100111. Epub 2014 Aug 4.

22.

TRP14 inhibits osteoclast differentiation via its catalytic activity.

Hong S, Huh JE, Lee SY, Shim JK, Rhee SG, Jeong W.

Mol Cell Biol. 2014 Sep 15;34(18):3515-24. doi: 10.1128/MCB.00293-14. Epub 2014 Jul 7.

23.

Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabody.

Koo MY, Park J, Lim JM, Joo SY, Shin SP, Shim HB, Chung J, Kang D, Woo HA, Rhee SG.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6269-74. doi: 10.1073/pnas.1316815111. Epub 2014 Apr 14.

24.

Dominant role of peroxiredoxin/JNK axis in stemness regulation during neurogenesis from embryonic stem cells.

Kim SU, Park YH, Kim JM, Sun HN, Song IS, Huang SM, Lee SH, Chae JI, Hong S, Sik Choi S, Choi SC, Lee TH, Kang SW, Rhee SG, Chang KT, Lee SH, Yu DY, Lee DS.

Stem Cells. 2014 Apr;32(4):998-1011. doi: 10.1002/stem.1593.

25.

Reflections on the days of phospholipase C.

Rhee SG.

Adv Biol Regul. 2013 Sep;53(3):223-31. doi: 10.1016/j.jbior.2013.08.004. Epub 2013 Sep 3. Review. No abstract available.

PMID:
24054839
26.

Ablation of peroxiredoxin II attenuates experimental colitis by increasing FoxO1-induced Foxp3+ regulatory T cells.

Won HY, Jang EJ, Lee K, Oh S, Kim HK, Woo HA, Kang SW, Yu DY, Rhee SG, Hwang ES.

J Immunol. 2013 Oct 15;191(8):4029-37. doi: 10.4049/jimmunol.1203247. Epub 2013 Sep 18.

27.

Study of the signaling function of sulfiredoxin and peroxiredoxin III in isolated adrenal gland: unsuitability of clonal and primary adrenocortical cells.

Kil IS, Bae SH, Rhee SG.

Methods Enzymol. 2013;527:169-81. doi: 10.1016/B978-0-12-405882-8.00009-X.

PMID:
23830631
28.

Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage.

Bae SH, Sung SH, Oh SY, Lim JM, Lee SK, Park YN, Lee HE, Kang D, Rhee SG.

Cell Metab. 2013 Jan 8;17(1):73-84. doi: 10.1016/j.cmet.2012.12.002. Epub 2012 Dec 27.

29.

Peroxiredoxin II is essential for preventing hemolytic anemia from oxidative stress through maintaining hemoglobin stability.

Han YH, Kim SU, Kwon TH, Lee DS, Ha HL, Park DS, Woo EJ, Lee SH, Kim JM, Chae HB, Lee SY, Kim BY, Yoon DY, Rhee SG, Fibach E, Yu DY.

Biochem Biophys Res Commun. 2012 Sep 28;426(3):427-32. doi: 10.1016/j.bbrc.2012.08.113. Epub 2012 Aug 30.

PMID:
22960070
30.

Feedback control of adrenal steroidogenesis via H2O2-dependent, reversible inactivation of peroxiredoxin III in mitochondria.

Kil IS, Lee SK, Ryu KW, Woo HA, Hu MC, Bae SH, Rhee SG.

Mol Cell. 2012 Jun 8;46(5):584-94. doi: 10.1016/j.molcel.2012.05.030.

31.

Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression.

Jeong W, Bae SH, Toledano MB, Rhee SG.

Free Radic Biol Med. 2012 Aug 1;53(3):447-56. doi: 10.1016/j.freeradbiomed.2012.05.020. Epub 2012 May 24. Review.

PMID:
22634055
32.

A fluorescence turn-on H2O2 probe exhibits lysosome-localized fluorescence signals.

Song D, Lim JM, Cho S, Park SJ, Cho J, Kang D, Rhee SG, You Y, Nam W.

Chem Commun (Camb). 2012 Jun 4;48(44):5449-51. doi: 10.1039/c2cc31632c. Epub 2012 Apr 26.

PMID:
22535325
33.

Peroxiredoxin III and sulfiredoxin together protect mice from pyrazole-induced oxidative liver injury.

Bae SH, Sung SH, Lee HE, Kang HT, Lee SK, Oh SY, Woo HA, Kil IS, Rhee SG.

Antioxid Redox Signal. 2012 Nov 15;17(10):1351-61. doi: 10.1089/ars.2011.4334. Epub 2012 May 31.

34.

Regulation of reactive oxygen species generation in cell signaling.

Bae YS, Oh H, Rhee SG, Yoo YD.

Mol Cells. 2011 Dec;32(6):491-509. doi: 10.1007/s10059-011-0276-3. Epub 2011 Dec 22. Review.

35.

Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxides.

Rhee SG, Woo HA, Kil IS, Bae SH.

J Biol Chem. 2012 Feb 10;287(7):4403-10. doi: 10.1074/jbc.R111.283432. Epub 2011 Dec 6. Review.

36.

Protein glutathionylation in the regulation of peroxiredoxins: a family of thiol-specific peroxidases that function as antioxidants, molecular chaperones, and signal modulators.

Chae HZ, Oubrahim H, Park JW, Rhee SG, Chock PB.

Antioxid Redox Signal. 2012 Mar 15;16(6):506-23. doi: 10.1089/ars.2011.4260. Review.

37.

Sulfiredoxin protein is critical for redox balance and survival of cells exposed to low steady-state levels of H2O2.

Baek JY, Han SH, Sung SH, Lee HE, Kim YM, Noh YH, Bae SH, Rhee SG, Chang TS.

J Biol Chem. 2012 Jan 2;287(1):81-9. doi: 10.1074/jbc.M111.316711. Epub 2011 Nov 15.

38.

An RNA aptamer that specifically binds pancreatic adenocarcinoma up-regulated factor inhibits migration and growth of pancreatic cancer cells.

Kim YH, Sung HJ, Kim S, Kim EO, Lee JW, Moon JY, Choi K, Jung JE, Lee Y, Koh SS, Rhee SG, Heo K, Kim IH.

Cancer Lett. 2011 Dec 26;313(1):76-83. doi: 10.1016/j.canlet.2011.08.027. Epub 2011 Sep 3.

PMID:
21963224
39.

Peroxiredoxin 3 is a key molecule regulating adipocyte oxidative stress, mitochondrial biogenesis, and adipokine expression.

Huh JY, Kim Y, Jeong J, Park J, Kim I, Huh KH, Kim YS, Woo HA, Rhee SG, Lee KJ, Ha H.

Antioxid Redox Signal. 2012 Feb 1;16(3):229-43. doi: 10.1089/ars.2011.3952. Epub 2011 Oct 17.

40.

Identification and characterization of alternatively transcribed form of peroxiredoxin IV gene that is specifically expressed in spermatids of postpubertal mouse testis.

Yim SH, Kim YJ, Oh SY, Fujii J, Zhang Y, Gladyshev VN, Rhee SG.

J Biol Chem. 2011 Nov 11;286(45):39002-12. doi: 10.1074/jbc.M111.257220. Epub 2011 Aug 11.

41.

Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice.

Park JG, Yoo JY, Jeong SJ, Choi JH, Lee MR, Lee MN, Hwa Lee J, Kim HC, Jo H, Yu DY, Kang SW, Rhee SG, Lee MH, Oh GT.

Circ Res. 2011 Sep 16;109(7):739-49. doi: 10.1161/CIRCRESAHA.111.245530. Epub 2011 Aug 11.

42.

Antibodies against non-immunizing antigens derived from a large immune scFv library.

Moon SA, Ki MK, Lee S, Hong ML, Kim M, Kim S, Chung J, Rhee SG, Shim H.

Mol Cells. 2011 Jun;31(6):509-13. doi: 10.1007/s10059-011-2268-8. Epub 2011 Apr 15.

43.

Unraveling the biological roles of reactive oxygen species.

Murphy MP, Holmgren A, Larsson NG, Halliwell B, Chang CJ, Kalyanaraman B, Rhee SG, Thornalley PJ, Partridge L, Gems D, Nyström T, Belousov V, Schumacker PT, Winterbourn CC.

Cell Metab. 2011 Apr 6;13(4):361-366. doi: 10.1016/j.cmet.2011.03.010.

44.

Glutathionylation of peroxiredoxin I induces decamer to dimers dissociation with concomitant loss of chaperone activity.

Park JW, Piszczek G, Rhee SG, Chock PB.

Biochemistry. 2011 Apr 19;50(15):3204-10. doi: 10.1021/bi101373h. Epub 2011 Mar 25.

45.

Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver.

Bae SH, Sung SH, Cho EJ, Lee SK, Lee HE, Woo HA, Yu DY, Kil IS, Rhee SG.

Hepatology. 2011 Mar;53(3):945-53. doi: 10.1002/hep.24104. Epub 2011 Feb 11.

PMID:
21319188
46.

Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger H₂O₂, and protein chaperones.

Rhee SG, Woo HA.

Antioxid Redox Signal. 2011 Aug 1;15(3):781-94. doi: 10.1089/ars.2010.3393. Epub 2011 Mar 31. Review.

PMID:
20919930
47.

Redox regulation of lipopolysaccharide-mediated sulfiredoxin induction, which depends on both AP-1 and Nrf2.

Kim H, Jung Y, Shin BS, Kim H, Song H, Bae SH, Rhee SG, Jeong W.

J Biol Chem. 2010 Nov 5;285(45):34419-28. doi: 10.1074/jbc.M110.126839. Epub 2010 Sep 7.

48.

Blot-based detection of dehydroalanine-containing glutathione peroxidase with the use of biotin-conjugated cysteamine.

Rhee SG, Cho CS.

Methods Enzymol. 2010;474:23-34. doi: 10.1016/S0076-6879(10)74002-7. Epub 2010 Jun 20.

PMID:
20609902
49.

Methods for detection and measurement of hydrogen peroxide inside and outside of cells.

Rhee SG, Chang TS, Jeong W, Kang D.

Mol Cells. 2010 Jun;29(6):539-49. doi: 10.1007/s10059-010-0082-3. Epub 2010 Jun 4. Review.

50.

B- to plasma-cell terminal differentiation entails oxidative stress and profound reshaping of the antioxidant responses.

Bertolotti M, Yim SH, Garcia-Manteiga JM, Masciarelli S, Kim YJ, Kang MH, Iuchi Y, Fujii J, Vené R, Rubartelli A, Rhee SG, Sitia R.

Antioxid Redox Signal. 2010 Oct;13(8):1133-44. doi: 10.1089/ars.2009.3079.

PMID:
20486764

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