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Author response: Age and sex differences in burnout, career satisfaction, and well-being in US neurologists.

LaFaver K, Miyasaki JM, Keran CM, Rheaume C, Gulya L, Levin KH, Jones EC, Schwarz HB, Molano JR, Hessler A, Singhal D, Shanafelt TD, Sloan JA, Novotny PJ, Cascino TL, Busis NA.

Neurology. 2019 Nov 5;93(19):863. doi: 10.1212/WNL.0000000000008451. No abstract available.


What methods have been used to estimate salt intake? A systematic review.

Perin MS, Gallani MCBJ, Andrechuk CRS, São-João TM, Rhéaume C, Cornélio ME.

Int J Food Sci Nutr. 2020 Feb;71(1):22-35. doi: 10.1080/09637486.2019.1620185. Epub 2019 May 31.


Deteriorated Cardiometabolic Risk Profile in Individuals With Excessive Blood Pressure Response to Submaximal Exercise.

Côté CE, Rhéaume C, Poirier P, Després JP, Alméras N.

Am J Hypertens. 2019 Sep 24;32(10):945-952. doi: 10.1093/ajh/hpz087.


Patient Stakeholder Versus Physician Preferences Regarding Amyloid PET Testing.

Armstrong MJ, Gronseth GS, Day GS, Rheaume C, Alliance S, Mullins CD.

Alzheimer Dis Assoc Disord. 2019 Jul-Sep;33(3):246-253. doi: 10.1097/WAD.0000000000000311.


Nutrient intake and dietary quality changes within a personalized lifestyle intervention program for metabolic syndrome in primary care.

Brauer P, Royall D, Li A, Rodrigues A, Green J, Macklin S, Craig A, Pasanen J, Brunelle L, Maitland S, Dhaliwal R, Klein D, Tremblay A, Rheaume C, Mutch DM, Jeejeebhoy K.

Appl Physiol Nutr Metab. 2019 Dec;44(12):1297-1304. doi: 10.1139/apnm-2019-0070. Epub 2019 Apr 30.


Design and Validation with Influenza A Virus of an Aerosol Transmission Chamber for Ferrets.

Turgeon N, Hamelin MÈ, Verreault D, Lévesque A, Rhéaume C, Carbonneau J, Checkmahomed L, Girard M, Boivin G, Duchaine C.

Int J Environ Res Public Health. 2019 Feb 19;16(4). pii: E609. doi: 10.3390/ijerph16040609.


Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures.

Pizzorno A, Terrier O, Nicolas de Lamballerie C, Julien T, Padey B, Traversier A, Roche M, Hamelin ME, Rhéaume C, Croze S, Escuret V, Poissy J, Lina B, Legras-Lachuer C, Textoris J, Boivin G, Rosa-Calatrava M.

Front Immunol. 2019 Jan 29;10:60. doi: 10.3389/fimmu.2019.00060. eCollection 2019.


The recruitment of peripheral blood leukocytes to the brain is delayed in susceptible BALB/c compared to resistant C57BL/6 mice during herpes simplex virus encephalitis.

Canivet C, Uyar O, Rhéaume C, Piret J, Boivin G.

J Neurovirol. 2019 Jun;25(3):372-383. doi: 10.1007/s13365-019-00730-5. Epub 2019 Feb 13.


Drug samples in family medicine teaching units: a cross-sectional descriptive study: Part 3: availability and use of drug samples in Quebec.

Lussier MT, Diallo FB, Pluye P, Grad R, Lessard A, Rhéaume C, Labrecque M.

Can Fam Physician. 2018 Dec;64(12):e546-e552.


Drug samples in family medicine teaching units: a cross-sectional descriptive study: Part 2: portrait of drug sample management in Quebec.

Lessard A, Lussier MT, Diallo FB, Labrecque M, Rhéaume C, Pluye P, Grad R.

Can Fam Physician. 2018 Dec;64(12):e540-e545.


Drug samples in family medicine teaching units: a cross-sectional descriptive study: Part 1: drug sample management policies and the relationship between the pharmaceutical industry and residents in Quebec.

Rhéaume C, Labrecque M, Moisan N, Rioux J, Tardieux É, Diallo FB, Lussier MT, Lessard A, Grad R, Pluye P.

Can Fam Physician. 2018 Dec;64(12):e531-e539.


Dietary sources of salt intake in adults and older people: a population-based study in a Brazilian town.

Perin MS, Cornélio ME, Oliveira HC, São-João TM, Rhéaume C, Gallani MBJ.

Public Health Nutr. 2019 Jun;22(8):1388-1397. doi: 10.1017/S1368980018003233. Epub 2018 Nov 26.


Age and sex differences in burnout, career satisfaction, and well-being in US neurologists.

LaFaver K, Miyasaki JM, Keran CM, Rheaume C, Gulya L, Levin KH, Jones EC, Schwarz HB, Molano JR, Hessler A, Singhal D, Shanafelt TD, Sloan JA, Novotny PJ, Cascino TL, Busis NA.

Neurology. 2018 Nov 13;91(20):e1928-e1941. doi: 10.1212/WNL.0000000000006497. Epub 2018 Oct 10.


Patient experiences of a lifestyle program for metabolic syndrome offered in family medicine clinics: a mixed methods study.

Klein J, Brauer P, Royall D, Israeloff-Smith M, Klein D, Tremblay A, Dhaliwal R, Rheaume C, Mutch DM, Jeejeebhoy K.

BMC Fam Pract. 2018 Aug 31;19(1):148. doi: 10.1186/s12875-018-0837-z.


Interdisciplinary teaching in family medicine teaching units: the residents' points of view.

Dallaire LF, Rhéaume C, Vézina L.

Can Med Educ J. 2018 Jul 27;9(3):e25-e40. eCollection 2018 Jul.


Both IRF3 and especially IRF7 play a key role to orchestrate an effective cerebral inflammatory response in a mouse model of herpes simplex virus encephalitis.

Canivet C, Rhéaume C, Lebel M, Piret J, Gosselin J, Boivin G.

J Neurovirol. 2018 Dec;24(6):761-768. doi: 10.1007/s13365-018-0666-9. Epub 2018 Aug 9.


Zika-Induced Male Infertility in Mice Is Potentially Reversible and Preventable by Deoxyribonucleic Acid Immunization.

de La Vega MA, Piret J, Griffin BD, Rhéaume C, Venable MC, Carbonneau J, Couture C, das Neves Almeida R, Tremblay RR, Magalhães KG, Park YK, Roberts CC, Maslow JN, Sardesai NY, Kim JJ, Muthumani K, Weiner DB, Kobinger GP, Boivin G.

J Infect Dis. 2019 Jan 9;219(3):365-374. doi: 10.1093/infdis/jiy336.


Efficacy and patient satisfaction of pelvic organ prolapse reduction using transvaginal mesh: A Canadian perspective.

Aubé M, Guérin M, Rheaume C, Tu LM.

Can Urol Assoc J. 2018 Oct;12(10):E432-E437. doi: 10.5489/cuaj.5095. Epub 2018 May 28.


Author response: Qualitative study of burnout, career satisfaction, and well-being among US neurologists in 2016.

Miyasaki JM, Rheaume C, Gulya L, Ellenstein A, Schwarz H, Vidic T, Shanafelt T, Cascino T, Keran C, Busis N.

Neurology. 2018 May 8;90(19):903. doi: 10.1212/WNL.0000000000005487. No abstract available.


Predominant role of IPS-1 over TRIF adaptor proteins in early innate immune response against Zika virus in mice.

Piret J, Carbonneau J, Rhéaume C, Baz M, Boivin G.

J Gen Virol. 2018 Feb;99(2):209-218. doi: 10.1099/jgv.0.000992. Epub 2018 Jan 3.


Protease-activated receptor 1 inhibition protects mice against thrombin-dependent respiratory syncytial virus and human metapneumovirus infections.

Lê VB, Riteau B, Alessi MC, Couture C, Jandrot-Perrus M, Rhéaume C, Hamelin MÈ, Boivin G.

Br J Pharmacol. 2018 Jan;175(2):388-403. doi: 10.1111/bph.14084. Epub 2017 Dec 10.


Qualitative study of burnout, career satisfaction, and well-being among US neurologists in 2016.

Miyasaki JM, Rheaume C, Gulya L, Ellenstein A, Schwarz HB, Vidic TR, Shanafelt TD, Cascino TL, Keran CM, Busis NA.

Neurology. 2017 Oct 17;89(16):1730-1738. doi: 10.1212/WNL.0000000000004526. Epub 2017 Sep 20.


The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus.

Fage C, Pizzorno A, Rhéaume C, Abed Y, Boivin G.

J Med Virol. 2017 Dec;89(12):2239-2243. doi: 10.1002/jmv.24911. Epub 2017 Aug 25.


The CHANGE program: Exercise intervention in primary care.

Klein D, Jeejeebhoy K, Tremblay A, Kallio M, Rheaume C, Humphries S, Royall D, Brauer P, Heyland D, Dhaliwal R, Mutch DM.

Can Fam Physician. 2017 Jul;63(7):546-552.


In vitro and in vivo evidence of a potential A(H1N1)pdm09 antigenic drift mediated by escape mutations in the haemagglutinin Sa antigenic site.

Retamal M, Abed Y, Rhéaume C, Baz M, Boivin G.

J Gen Virol. 2017 Jun;98(6):1224-1231. doi: 10.1099/jgv.0.000800. Epub 2017 Jun 20.


Family physician-led, team-based, lifestyle intervention in patients with metabolic syndrome: results of a multicentre feasibility project.

Jeejeebhoy K, Dhaliwal R, Heyland DK, Leung R, Day AG, Brauer P, Royall D, Tremblay A, Mutch DM, Pliamm L, Rhéaume C, Klein D.

CMAJ Open. 2017 Mar 14;5(1):E229-E236. doi: 10.9778/cmajo.20160101. eCollection 2017 Jan-Mar. Erratum in: CMAJ Open. 2017 May 1;5(2):E337.


Naturalistic study of guideline implementation tool use via evaluation of website access and physician survey.

Armstrong MJ, Gronseth GS, Dubinsky R, Potrebic S, Penfold Murray R, Getchius TS, Rheaume C, Gagliardi AR.

BMC Med Inform Decis Mak. 2017 Jan 13;17(1):9. doi: 10.1186/s12911-016-0404-2.


The E119D neuraminidase mutation identified in a multidrug-resistant influenza A(H1N1)pdm09 isolate severely alters viral fitness in vitro and in animal models.

Abed Y, Bouhy X, L'Huillier AG, Rhéaume C, Pizzorno A, Retamal M, Fage C, Dubé K, Joly MH, Beaulieu E, Mallett C, Kaiser L, Boivin G.

Antiviral Res. 2016 Aug;132:6-12. doi: 10.1016/j.antiviral.2016.05.006. Epub 2016 May 13.


Acute effects of protein composition and fibre enrichment of yogurt consumed as snacks on appetite sensations and subsequent ad libitum energy intake in healthy men.

Doyon CY, Tremblay A, Rioux LE, Rhéaume C, Cianflone K, Poursharifi P, Turgeon SL.

Appl Physiol Nutr Metab. 2015 Oct;40(10):980-9. doi: 10.1139/apnm-2014-0403. Epub 2015 Sep 22.


A 12-Week Exercise Program for Pregnant Women with Obesity to Improve Physical Activity Levels: An Open Randomised Preliminary Study.

Bisson M, Alméras N, Dufresne SS, Robitaille J, Rhéaume C, Bujold E, Frenette J, Tremblay A, Marc I.

PLoS One. 2015 Sep 16;10(9):e0137742. doi: 10.1371/journal.pone.0137742. eCollection 2015.


Valacyclovir combined with artesunate or rapamycin improves the outcome of herpes simplex virus encephalitis in mice compared to antiviral therapy alone.

Canivet C, Menasria R, Rhéaume C, Piret J, Boivin G.

Antiviral Res. 2015 Nov;123:105-13. doi: 10.1016/j.antiviral.2015.09.007. Epub 2015 Sep 14.


The Impact of Social Media on Dissemination and Implementation of Clinical Practice Guidelines: A Longitudinal Observational Study.

Narayanaswami P, Gronseth G, Dubinsky R, Penfold-Murray R, Cox J, Bever C Jr, Martins Y, Rheaume C, Shouse D, Getchius TS.

J Med Internet Res. 2015 Aug 13;17(8):e193. doi: 10.2196/jmir.4414.


A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25.

Rhéaume C, Cai BB, Wang J, Fernández-Salas E, Aoki KR, Francis J, Broide RS.

Toxins (Basel). 2015 Jun 24;7(7):2354-70. doi: 10.3390/toxins7072354.


Effect of in vitro syncytium formation on the severity of human metapneumovirus disease in a murine model.

Aerts L, Cavanagh MH, Dubois J, Carbonneau J, Rhéaume C, Lavigne S, Couture C, Hamelin MÈ, Boivin G.

PLoS One. 2015 Mar 24;10(3):e0120283. doi: 10.1371/journal.pone.0120283. eCollection 2015.


Heterosubtypic protection conferred by the human monoclonal antibody PN-SIA28 against influenza A virus lethal infections in mice.

Retamal M, Abed Y, Rhéaume C, Cappelletti F, Clementi N, Mancini N, Clementi M, Burioni R, Boivin G.

Antimicrob Agents Chemother. 2015 May;59(5):2647-53. doi: 10.1128/AAC.00118-15. Epub 2015 Feb 17.


Adjuvant effect of the human metapneumovirus (HMPV) matrix protein in HMPV subunit vaccines.

Aerts L, Rhéaume C, Carbonneau J, Lavigne S, Couture C, Hamelin MÈ, Boivin G.

J Gen Virol. 2015 Apr;96(Pt 4):767-74. doi: 10.1099/vir.0.000031. Epub 2014 Dec 17.


Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines.

Ann J, Samant M, Rheaume C, Dumas C, Beaulieu E, Morasse A, Mallett C, Hamelin ME, Papadopoulou B, Boivin G.

Vaccine. 2014 Sep 29;32(43):5730-9. doi: 10.1016/j.vaccine.2014.08.029. Epub 2014 Aug 27.


Impact of abdominal obesity and systemic hypertension on risk of coronary heart disease in men and women: the EPIC-Norfolk Population Study.

Rhéaume C, Arsenault BJ, Després JP, Faha, Boekholdt SM, Wareham NJ, Khaw KT, Chir M.

J Hypertens. 2014 Nov;32(11):2224-30; discussion 2230. doi: 10.1097/HJH.0000000000000307.


Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia.

Sun P, Watanabe K, Fallahi M, Lee B, Afetian ME, Rheaume C, Wu D, Horsley V, Dai X.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10215-20. doi: 10.1073/pnas.1311395111. Epub 2014 Jun 30.


Modulation of blood pressure response to exercise by physical activity and relationship with resting blood pressure during pregnancy.

Bisson M, Rhéaume C, Bujold E, Tremblay A, Marc I.

J Hypertens. 2014 Jul;32(7):1450-7; discussion 1457. doi: 10.1097/HJH.0000000000000185.


Oseltamivir-zanamivir combination therapy is not superior to zanamivir monotherapy in mice infected with influenza A(H3N2) and A(H1N1)pdm09 viruses.

Pizzorno A, Abed Y, Rhéaume C, Boivin G.

Antiviral Res. 2014 May;105:54-8. doi: 10.1016/j.antiviral.2014.02.017. Epub 2014 Feb 28.


Impact of DECISION + 2 on patient and physician assessment of shared decision making implementation in the context of antibiotics use for acute respiratory infections.

Légaré F, Guerrier M, Nadeau C, Rhéaume C, Turcotte S, Labrecque M.

Implement Sci. 2013 Dec 26;8:144. doi: 10.1186/1748-5908-8-144.


Impact of potential permissive neuraminidase mutations on viral fitness of the H275Y oseltamivir-resistant influenza A(H1N1)pdm09 virus in vitro, in mice and in ferrets.

Abed Y, Pizzorno A, Bouhy X, Rhéaume C, Boivin G.

J Virol. 2014 Feb;88(3):1652-8. doi: 10.1128/JVI.02681-13. Epub 2013 Nov 20.


Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model.

Aerts L, Hamelin MÈ, Rhéaume C, Lavigne S, Couture C, Kim W, Susan-Resiga D, Prat A, Seidah NG, Vergnolle N, Riteau B, Boivin G.

PLoS One. 2013 Aug 28;8(8):e72529. doi: 10.1371/journal.pone.0072529. eCollection 2013.


Exercise-induced exaggerated blood pressure response in men with the metabolic syndrome: the role of the autonomous nervous system.

Gaudreault V, Després JP, Rhéaume C, Bergeron J, Alméras N, Tremblay A, Poirier P.

Blood Press Monit. 2013 Oct;18(5):252-8. doi: 10.1097/MBP.0b013e3283646f59.


The potential influence of masculine identity on health-improving behavior in midlife and older African American men.

Hooker SP, Wilcox S, Burroughs EL, Rheaume CE, Courtenay W.

J Mens Health. 2012 Jun 1;9(2):79-88.


Evaluation of recombinant 2009 pandemic influenza A (H1N1) viruses harboring zanamivir resistance mutations in mice and ferrets.

Pizzorno A, Abed Y, Rhéaume C, Bouhy X, Boivin G.

Antimicrob Agents Chemother. 2013 Apr;57(4):1784-9. doi: 10.1128/AAC.02269-12. Epub 2013 Jan 28.


Maternal fitness at the onset of the second trimester of pregnancy: correlates and relationship with infant birth weight.

Bisson M, Alméras N, Plaisance J, Rhéaume C, Bujold E, Tremblay A, Marc I.

Pediatr Obes. 2013 Dec;8(6):464-74. doi: 10.1111/j.2047-6310.2012.00129.x. Epub 2012 Dec 20.


Exercise-induced hypertension in men with metabolic syndrome: anthropometric, metabolic, and hemodynamic features.

Gaudreault V, Després JP, Rhéaume C, Alméras N, Bergeron J, Tremblay A, Poirier P.

Metab Syndr Relat Disord. 2013 Feb;11(1):7-14. doi: 10.1089/met.2012.0071. Epub 2012 Dec 3.


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