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Items: 44

1.

Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease.

Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J, Bedi KC Jr, Margulies KB, Sanz-Moreno V, Hobbs A, Hodivala-Dilke K.

J Pathol. 2019 Aug 19. doi: 10.1002/path.5340. [Epub ahead of print]

PMID:
31424556
2.

Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.

Pedrosa AR, Bodrug N, Gomez-Escudero J, Carter EP, Reynolds LE, Georgiou PN, Fernandez I, Lees DM, Kostourou V, Alexopoulou AN, Batista S, Tavora B, Serrels B, Parsons M, Iskratsch T, Hodivala-Dilke KM.

Cancer Res. 2019 Sep 1;79(17):4371-4386. doi: 10.1158/0008-5472.CAN-18-3934. Epub 2019 Jun 12.

PMID:
31189647
3.

Work Practices and Respiratory Health Status of Appalachian Coal Miners With Progressive Massive Fibrosis.

Reynolds LE, Blackley DJ, Colinet JF, Potts JD, Storey E, Short C, Carson R, Clark KA, Laney AS, Halldin CN.

J Occup Environ Med. 2018 Nov;60(11):e575-e581. doi: 10.1097/JOM.0000000000001443.

4.

A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia.

Foxler DE, Bridge KS, Foster JG, Grevitt P, Curry S, Shah KM, Davidson KM, Nagano A, Gadaleta E, Rhys HI, Kennedy PT, Hermida MA, Chang TY, Shaw PE, Reynolds LE, McKay TR, Wang HW, Ribeiro PS, Plevin MJ, Lagos D, Lemoine NR, Rajan P, Graham TA, Chelala C, Hodivala-Dilke KM, Spendlove I, Sharp TV.

EMBO Mol Med. 2018 Aug;10(8). pii: e8304. doi: 10.15252/emmm.201708304.

5.

Progressive Massive Fibrosis in Coal Miners From 3 Clinics in Virginia.

Blackley DJ, Reynolds LE, Short C, Carson R, Storey E, Halldin CN, Laney AS.

JAMA. 2018 Feb 6;319(5):500-501. doi: 10.1001/jama.2017.18444. No abstract available.

6.

Strengthening the Coal Workers' Health Surveillance Program.

Reynolds LE, Wolfe AL, Clark KA, Blackley DJ, Halldin CN, Laney AS, Storey E.

J Occup Environ Med. 2017 Apr;59(4):e71. doi: 10.1097/JOM.0000000000000993. No abstract available.

7.

Respiratory morbidity among U.S. coal miners in states outside of central Appalachia.

Reynolds LE, Blackley DJ, Laney AS, Halldin CN.

Am J Ind Med. 2017 Jun;60(6):513-517. doi: 10.1002/ajim.22727. Epub 2017 May 12.

8.

Multiple roles of integrin-α3 at the neuromuscular junction.

Ross JA, Webster RG, Lechertier T, Reynolds LE, Turmaine M, Bencze M, Jamshidi Y, Cetin H, Muntoni F, Beeson D, Hodilvala-Dilke K, Conti FJ.

J Cell Sci. 2017 May 15;130(10):1772-1784. doi: 10.1242/jcs.201103. Epub 2017 Apr 6.

9.

Dual role of pericyte α6β1-integrin in tumour blood vessels.

Reynolds LE, D'Amico G, Lechertier T, Papachristodoulou A, Muñoz-Félix JM, De Arcangelis A, Baker M, Serrels B, Hodivala-Dilke KM.

J Cell Sci. 2017 May 1;130(9):1583-1595. doi: 10.1242/jcs.197848. Epub 2017 Mar 13.

10.

Endothelial FAK is required for tumour angiogenesis.

Tavora B, Batista S, Reynolds LE, Jadeja S, Robinson S, Kostourou V, Hart I, Fruttiger M, Parsons M, Hodivala-Dilke KM.

EMBO Mol Med. 2016 Oct 4;8(10):1229. doi: 10.15252/emmm.201606907. Print 2016 Oct. No abstract available.

11.

Interleukin-6 Stimulates Defective Angiogenesis.

Gopinathan G, Milagre C, Pearce OM, Reynolds LE, Hodivala-Dilke K, Leinster DA, Zhong H, Hollingsworth RE, Thompson R, Whiteford JR, Balkwill F.

Cancer Res. 2015 Aug 1;75(15):3098-107. doi: 10.1158/0008-5472.CAN-15-1227. Epub 2015 Jun 16.

12.

The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling.

Birdsey GM, Shah AV, Dufton N, Reynolds LE, Osuna Almagro L, Yang Y, Aspalter IM, Khan ST, Mason JC, Dejana E, Göttgens B, Hodivala-Dilke K, Gerhardt H, Adams RH, Randi AM.

Dev Cell. 2015 Jan 12;32(1):82-96. doi: 10.1016/j.devcel.2014.11.016.

13.

Haematopoietic focal adhesion kinase deficiency alters haematopoietic homeostasis to drive tumour metastasis.

Batista S, Maniati E, Reynolds LE, Tavora B, Lees DM, Fernandez I, Elia G, Casanovas O, Lo Celso C, Hagemann T, Hodivala-Dilke K.

Nat Commun. 2014 Oct 1;5:5054. doi: 10.1038/ncomms6054.

PMID:
25270220
14.

Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy.

Tavora B, Reynolds LE, Batista S, Demircioglu F, Fernandez I, Lechertier T, Lees DM, Wong PP, Alexopoulou A, Elia G, Clear A, Ledoux A, Hunter J, Perkins N, Gribben JG, Hodivala-Dilke KM.

Nature. 2014 Oct 2;514(7520):112-6. doi: 10.1038/nature13541. Epub 2014 Jul 27.

15.

Vaccinated children and adolescents with pertussis infections experience reduced illness severity and duration, Oregon, 2010-2012.

Barlow RS, Reynolds LE, Cieslak PR, Sullivan AD.

Clin Infect Dis. 2014 Jun;58(11):1523-9. doi: 10.1093/cid/ciu156. Epub 2014 Mar 14.

PMID:
24633685
16.

Fascin 1 is dispensable for developmental and tumour angiogenesis.

Ma Y, Reynolds LE, Li A, Stevenson RP, Hodivala-Dilke KM, Yamashiro S, Machesky LM.

Biol Open. 2013 Sep 19;2(11):1187-91. doi: 10.1242/bio.20136031. eCollection 2013.

17.

FAK-heterozygous mice display enhanced tumour angiogenesis.

Kostourou V, Lechertier T, Reynolds LE, Lees DM, Baker M, Jones DT, Tavora B, Ramjaun AR, Birdsey GM, Robinson SD, Parsons M, Randi AM, Hart IR, Hodivala-Dilke K.

Nat Commun. 2013;4:2020. doi: 10.1038/ncomms3020.

18.

Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen-1 and nidogen-2.

Martino-Echarri E, Fernández-Rodríguez R, Rodríguez-Baena FJ, Barrientos-Durán A, Torres-Collado AX, Plaza-Calonge Mdel C, Amador-Cubero S, Cortés J, Reynolds LE, Hodivala-Dilke KM, Rodríguez-Manzaneque JC.

Int J Cancer. 2013 Nov 15;133(10):2315-24. doi: 10.1002/ijc.28271. Epub 2013 Jun 13.

19.

Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth.

Baker M, Reynolds LE, Robinson SD, Lees DM, Parsons M, Elia G, Hodivala-Dilke K.

PLoS One. 2013 May 13;8(5):e62516. doi: 10.1371/journal.pone.0062516. Print 2013.

20.

Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice.

Jones DT, Lechertier T, Reynolds LE, Mitter R, Robinson SD, Kirn-Safran CB, Hodivala-Dilke KM.

Dis Model Mech. 2013 Jan;6(1):115-24. doi: 10.1242/dmm.009183. Epub 2012 Nov 1.

21.

β3-integrin is required for differentiation in OC-2 cells derived from mammalian embryonic inner ear.

Brunetta I, Casalotti SO, Hart IR, Forge A, Reynolds LE.

BMC Cell Biol. 2012 Mar 17;13:5. doi: 10.1186/1471-2121-13-5.

22.

Endothelial FAK is required for tumour angiogenesis.

Tavora B, Batista S, Reynolds LE, Jadeja S, Robinson S, Kostourou V, Hart I, Fruttiger M, Parsons M, Hodivala-Dilke KM.

EMBO Mol Med. 2010 Dec;2(12):516-28. doi: 10.1002/emmm.201000106. Erratum in: EMBO Mol Med. 2016 Oct 4;8(10 ):1229.

23.

Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.

da Silva RG, Tavora B, Robinson SD, Reynolds LE, Szekeres C, Lamar J, Batista S, Kostourou V, Germain MA, Reynolds AR, Jones DT, Watson AR, Jones JL, Harris A, Hart IR, Iruela-Arispe ML, Dipersio CM, Kreidberg JA, Hodivala-Dilke KM.

Am J Pathol. 2010 Sep;177(3):1534-48. doi: 10.2353/ajpath.2010.100043. Epub 2010 Jul 16.

24.

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.

Reynolds LE, Watson AR, Baker M, Jones TA, D'Amico G, Robinson SD, Joffre C, Garrido-Urbani S, Rodriguez-Manzaneque JC, Martino-Echarri E, Aurrand-Lions M, Sheer D, Dagna-Bricarelli F, Nizetic D, McCabe CJ, Turnell AS, Kermorgant S, Imhof BA, Adams R, Fisher EM, Tybulewicz VL, Hart IR, Hodivala-Dilke KM.

Nature. 2010 Jun 10;465(7299):813-7. doi: 10.1038/nature09106. Erratum in: Nature. 2010 Jul 15;466(7304):398.

25.

Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent.

D'Amico G, Robinson SD, Germain M, Reynolds LE, Thomas GJ, Elia G, Saunders G, Fruttiger M, Tybulewicz V, Mavria G, Hodivala-Dilke KM.

PLoS One. 2010 Mar 22;5(3):e9766. doi: 10.1371/journal.pone.0009766.

26.

Deficiency of bone marrow beta3-integrin enhances non-functional neovascularization.

Watson AR, Pitchford SC, Reynolds LE, Direkze N, Brittan M, Alison MR, Rankin S, Wright NA, Hodivala-Dilke KM.

J Pathol. 2010 Mar;220(4):435-45. doi: 10.1002/path.2660.

PMID:
19967726
27.

Genetic ablation of the alpha 6-integrin subunit in Tie1Cre mice enhances tumour angiogenesis.

Germain M, De Arcangelis A, Robinson SD, Baker M, Tavora B, D'Amico G, Silva R, Kostourou V, Reynolds LE, Watson A, Jones JL, Georges-Labouesse E, Hodivala-Dilke K.

J Pathol. 2010 Feb;220(3):370-81. doi: 10.1002/path.2654.

PMID:
19967723
28.

Regulation of lymphatic-blood vessel separation by endothelial Rac1.

D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V, Martinez D, Aubyn D, Grose R, Thomas GJ, Spencer-Dene B, Zicha D, Davies D, Tybulewicz V, Hodivala-Dilke KM.

Development. 2009 Dec;136(23):4043-53. doi: 10.1242/dev.035014. Erratum in: Development. 2010 Jan;137(2):359.

29.

Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis.

Robinson SD, Reynolds LE, Kostourou V, Reynolds AR, da Silva RG, Tavora B, Baker M, Marshall JF, Hodivala-Dilke KM.

J Biol Chem. 2009 Dec 4;284(49):33966-81. doi: 10.1074/jbc.M109.030700. Epub 2009 Oct 16.

30.

Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation.

Radke AL, Reynolds LE, Melo RC, Dvorak AM, Weller PF, Spencer LA.

Blood. 2009 Mar 26;113(13):3092-101. doi: 10.1182/blood-2008-05-155937. Epub 2009 Jan 26.

31.

Integrins: the keys to unlocking angiogenesis.

Silva R, D'Amico G, Hodivala-Dilke KM, Reynolds LE.

Arterioscler Thromb Vasc Biol. 2008 Oct;28(10):1703-13. doi: 10.1161/ATVBAHA.108.172015. Epub 2008 Jul 24. Review.

PMID:
18658045
32.

alpha3beta1 integrin-controlled Smad7 regulates reepithelialization during wound healing in mice.

Reynolds LE, Conti FJ, Silva R, Robinson SD, Iyer V, Rudling R, Cross B, Nye E, Hart IR, Dipersio CM, Hodivala-Dilke KM.

J Clin Invest. 2008 Mar;118(3):965-74. doi: 10.1172/JCI33538.

33.

Primary mouse endothelial cell culture for assays of angiogenesis.

Reynolds LE, Hodivala-Dilke KM.

Methods Mol Med. 2006;120:503-9.

PMID:
16491622
34.

Accelerated re-epithelialization in beta3-integrin-deficient- mice is associated with enhanced TGF-beta1 signaling.

Reynolds LE, Conti FJ, Lucas M, Grose R, Robinson S, Stone M, Saunders G, Dickson C, Hynes RO, Lacy-Hulbert A, Hodivala-Dilke K.

Nat Med. 2005 Feb;11(2):167-74. Epub 2005 Jan 16.

PMID:
15654327
35.

Elevated Flk1 (vascular endothelial growth factor receptor 2) signaling mediates enhanced angiogenesis in beta3-integrin-deficient mice.

Reynolds AR, Reynolds LE, Nagel TE, Lively JC, Robinson SD, Hicklin DJ, Bodary SC, Hodivala-Dilke KM.

Cancer Res. 2004 Dec 1;64(23):8643-50.

36.

Bone marrow cells engraft within the epidermis and proliferate in vivo with no evidence of cell fusion.

Brittan M, Braun KM, Reynolds LE, Conti FJ, Reynolds AR, Poulsom R, Alison MR, Wright NA, Hodivala-Dilke KM.

J Pathol. 2005 Jan;205(1):1-13.

PMID:
15546160
37.

Beta3-integrin regulates vascular endothelial growth factor-A-dependent permeability.

Robinson SD, Reynolds LE, Wyder L, Hicklin DJ, Hodivala-Dilke KM.

Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2108-14. Epub 2004 Sep 2.

PMID:
15345507
38.

Integrins in angiogenesis: multitalented molecules in a balancing act.

Hodivala-Dilke KM, Reynolds AR, Reynolds LE.

Cell Tissue Res. 2003 Oct;314(1):131-44. Epub 2003 Sep 10. Review.

PMID:
13680353
39.

Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes.

Wan H, Stone MG, Simpson C, Reynolds LE, Marshall JF, Hart IR, Hodivala-Dilke KM, Eady RA.

J Cell Sci. 2003 Oct 15;116(Pt 20):4239-48. Epub 2003 Sep 2.

40.

Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins.

Reynolds LE, Wyder L, Lively JC, Taverna D, Robinson SD, Huang X, Sheppard D, Hynes RO, Hodivala-Dilke KM.

Nat Med. 2002 Jan;8(1):27-34.

PMID:
11786903
41.

Elevated plasma motilin concentrations in chronic renal disease.

McLeod RS, Track NS, Reynolds LE.

Can Med Assoc J. 1979 Aug 4;121(3):268-73. No abstract available.

42.

Effects of local chilling in the treatment of burns.

BROWN CR, PRICE PB, REYNOLDS LE.

Surg Forum. 1956;6:85-7. No abstract available.

PMID:
13391423
43.

Local edema and capillary permeability associated with burn wounds.

KING TC, PRICE PB, REYNOLDS LE.

Surg Forum. 1956;6:80-4. No abstract available.

PMID:
13391422
44.

Meconium peritonitis.

PACKARD GB, REYNOLDS LE.

Ann Surg. 1951 Apr;133(4):548-54. No abstract available.

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