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How do information sources influence the reported Cerebral Performance Category (CPC) for in-hospital cardiac arrest survivors? An observational study from the UK National Cardiac Arrest Audit (NCAA).

Reynolds EC, Zenasni Z, Harrison DA, Rowan KM, Nolan JP, Soar J; National Cardiac Arrest Audit.

Resuscitation. 2019 Jun 12;141:19-23. doi: 10.1016/j.resuscitation.2019.05.035. [Epub ahead of print]


IL-36γ regulates mediators of tissue homeostasis in epithelial cells.

Heath JE, Scholz GM, Veith PD, Reynolds EC.

Cytokine. 2019 Jul;119:24-31. doi: 10.1016/j.cyto.2019.02.012. Epub 2019 Mar 8.


Genome-Wide Association Mapping of Floral Traits in Cultivated Sunflower (Helianthus annuus).

Dowell JA, Reynolds EC, Pliakas TP, Mandel JR, Burke JM, Donovan LA, Mason CM.

J Hered. 2019 May 7;110(3):275-286. doi: 10.1093/jhered/esz013.


Localization of Outer Membrane Proteins in Treponema denticola by Quantitative Proteome Analyses of Outer Membrane Vesicles and Cellular Fractions.

Veith PD, Glew MD, Gorasia DG, Chen D, O'Brien-Simpson NM, Reynolds EC.

J Proteome Res. 2019 Apr 5;18(4):1567-1581. doi: 10.1021/acs.jproteome.8b00860. Epub 2019 Feb 26.


Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.

Dominy SS, Lynch C, Ermini F, Benedyk M, Marczyk A, Konradi A, Nguyen M, Haditsch U, Raha D, Griffin C, Holsinger LJ, Arastu-Kapur S, Kaba S, Lee A, Ryder MI, Potempa B, Mydel P, Hellvard A, Adamowicz K, Hasturk H, Walker GD, Reynolds EC, Faull RLM, Curtis MA, Dragunow M, Potempa J.

Sci Adv. 2019 Jan 23;5(1):eaau3333. doi: 10.1126/sciadv.aau3333. eCollection 2019 Jan.


Self-assembly of dental surface nanofilaments and remineralisation by SnF2 and CPP-ACP nanocomplexes.

Fernando JR, Shen P, Sim CPC, Chen YY, Walker GD, Yuan Y, Reynolds C, Stanton DP, MacRae CM, Reynolds EC.

Sci Rep. 2019 Feb 4;9(1):1285. doi: 10.1038/s41598-018-37580-w.


Monospecies and polymicrobial biofilms differentially regulate the phenotype of genotype-specific oral cancer cells.

Arzmi MH, Cirillo N, Lenzo JC, Catmull DV, O'Brien-Simpson N, Reynolds EC, Dashper S, McCullough M.

Carcinogenesis. 2019 Mar 12;40(1):184-193. doi: 10.1093/carcin/bgy137.


CPP-ACP Promotes SnF2 Efficacy in a Polymicrobial Caries Model.

Dashper SG, Shen P, Sim CPC, Liu SW, Butler CA, Mitchell HL, D'Cruze T, Yuan Y, Hoffmann B, Walker GD, Catmull DV, Reynolds C, Reynolds EC.

J Dent Res. 2019 Feb;98(2):218-224. doi: 10.1177/0022034518809088. Epub 2018 Nov 4.


Anticariogenic efficacy of a saliva biomimetic in head-and-neck cancer patients undergoing radiotherapy.

Sim C, Walker GD, Manton DJ, Soong YL, Wee J, Adams GG, Reynolds EC.

Aust Dent J. 2019 Mar;64(1):47-54. doi: 10.1111/adj.12658. Epub 2018 Nov 11.


Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice.

Ilievski V, Zuchowska PK, Green SJ, Toth PT, Ragozzino ME, Le K, Aljewari HW, O'Brien-Simpson NM, Reynolds EC, Watanabe K.

PLoS One. 2018 Oct 3;13(10):e0204941. doi: 10.1371/journal.pone.0204941. eCollection 2018.


Architectural Effects of Star-Shaped "Structurally Nanoengineered Antimicrobial Peptide Polymers" (SNAPPs) on Their Biological Activity.

Shirbin SJ, Insua I, Holden JA, Lenzo JC, Reynolds EC, O'Brien-Simpson NM, Qiao GG.

Adv Healthc Mater. 2018 Nov;7(21):e1800627. doi: 10.1002/adhm.201800627. Epub 2018 Sep 2.


Importance of bioavailable calcium in fluoride dentifrices for enamel remineralization.

Shen P, Walker GD, Yuan Y, Reynolds C, Stanton DP, Fernando JR, Reynolds EC.

J Dent. 2018 Nov;78:59-64. doi: 10.1016/j.jdent.2018.08.005. Epub 2018 Aug 9.


Porphyromonas gingivalis Gingipains Display Transpeptidation Activity.

Zhang L, Veith PD, Huq NL, Chen YY, Seers CA, Cross KJ, Gorasia DG, Reynolds EC.

J Proteome Res. 2018 Aug 3;17(8):2803-2818. doi: 10.1021/acs.jproteome.8b00286. Epub 2018 Jul 20.


Regulation of the Peptidoglycan Amidase PGLYRP2 in Epithelial Cells by Interleukin-36γ.

Scholz GM, Heath JE, Aw J, Reynolds EC.

Infect Immun. 2018 Aug 22;86(9). pii: e00384-18. doi: 10.1128/IAI.00384-18. Print 2018 Sep.


Outer Membrane Vesicle Proteome of Porphyromonas gingivalis Is Differentially Modulated Relative to the Outer Membrane in Response to Heme Availability.

Veith PD, Luong C, Tan KH, Dashper SG, Reynolds EC.

J Proteome Res. 2018 Jul 6;17(7):2377-2389. doi: 10.1021/acs.jproteome.8b00153. Epub 2018 May 29.


CRISPR genetic screens to discover host-virus interactions.

McDougall WM, Perreira JM, Reynolds EC, Brass AL.

Curr Opin Virol. 2018 Apr;29:87-100. doi: 10.1016/j.coviro.2018.03.007. Review.


Xerostomia, salivary characteristics and gland volumes following intensity-modulated radiotherapy for nasopharyngeal carcinoma: a two-year follow up.

Sim C, Soong YL, Pang E, Lim C, Walker GD, Manton DJ, Reynolds EC, Wee J.

Aust Dent J. 2018 Jun;63(2):217-223. doi: 10.1111/adj.12608. Epub 2018 Apr 24.


The Bacteroidetes Q-Rule: Pyroglutamate in Signal Peptidase I Substrates.

Bochtler M, Mizgalska D, Veillard F, Nowak ML, Houston J, Veith P, Reynolds EC, Potempa J.

Front Microbiol. 2018 Mar 1;9:230. doi: 10.3389/fmicb.2018.00230. eCollection 2018.


Interplay between Porphyromonas gingivalis and EGF signalling in the regulation of CXCL14.

Aw J, Scholz GM, Huq NL, Huynh J, O'Brien-Simpson NM, Reynolds EC.

Cell Microbiol. 2018 Jul;20(7):e12837. doi: 10.1111/cmi.12837. Epub 2018 Mar 23.


MEK-ERK signaling diametrically controls the stimulation of IL-23p19 and EBI3 expression in epithelial cells by IL-36γ.

Scholz GM, Heath JE, Walsh KA, Reynolds EC.

Immunol Cell Biol. 2018 Jul;96(6):646-655. doi: 10.1111/imcb.12029. Epub 2018 Mar 24.


Comparative study of novel in situ decorated porous chitosan-selenium scaffolds and porous chitosan-silver scaffolds towards antimicrobial wound dressing application.

Biswas DP, O'Brien-Simpson NM, Reynolds EC, O'Connor AJ, Tran PA.

J Colloid Interface Sci. 2018 Apr 1;515:78-91. doi: 10.1016/j.jcis.2018.01.007. Epub 2018 Jan 5.


Biocompatibility and Osteogenic/Calcification Potential of Casein Phosphopeptide-amorphous Calcium Phosphate Fluoride.

Dawood AE, Manton DJ, Parashos P, Wong RH, Singleton W, Holden JA, O'Brien-Simpson NM, Reynolds EC.

J Endod. 2018 Mar;44(3):452-457. doi: 10.1016/j.joen.2017.11.005. Epub 2017 Dec 21.


A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis.

O'Brien-Simpson NM, Holden JA, Lenzo JC, Tan Y, Brammar GC, Walsh KA, Singleton W, Orth RKH, Slakeski N, Cross KJ, Darby IB, Becher D, Rowe T, Morelli AB, Hammet A, Nash A, Brown A, Ma B, Vingadassalom D, McCluskey J, Kleanthous H, Reynolds EC.

NPJ Vaccines. 2016 Dec 1;1:16022. doi: 10.1038/npjvaccines.2016.22. eCollection 2016.


Adolescent temperament dimensions as stable prospective risk and protective factors for salivary C-reactive protein.

Nelson BW, Byrne ML, Simmons JG, Whittle S, Schwartz OS, O'Brien-Simpson NM, Walsh KA, Reynolds EC, Allen NB.

Br J Health Psychol. 2018 Feb;23(1):186-207. doi: 10.1111/bjhp.12281. Epub 2017 Oct 15.


Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo.

Cecil JD, O'Brien-Simpson NM, Lenzo JC, Holden JA, Singleton W, Perez-Gonzalez A, Mansell A, Reynolds EC.

Front Immunol. 2017 Aug 25;8:1017. doi: 10.3389/fimmu.2017.01017. eCollection 2017.


Polyols and remineralisation of enamel subsurface lesions.

Shen P, Walker GD, Yuan Y, Reynolds C, Reynolds EC.

J Dent. 2017 Nov;66:71-75. doi: 10.1016/j.jdent.2017.08.008. Epub 2017 Aug 30.


Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles.

Fleetwood AJ, Lee MKS, Singleton W, Achuthan A, Lee MC, O'Brien-Simpson NM, Cook AD, Murphy AJ, Dashper SG, Reynolds EC, Hamilton JA.

Front Cell Infect Microbiol. 2017 Aug 4;7:351. doi: 10.3389/fcimb.2017.00351. eCollection 2017.


PorV is an Outer Membrane Shuttle Protein for the Type IX Secretion System.

Glew MD, Veith PD, Chen D, Gorasia DG, Peng B, Reynolds EC.

Sci Rep. 2017 Aug 18;7(1):8790. doi: 10.1038/s41598-017-09412-w.


Bacterial membrane vesicles transport their DNA cargo into host cells.

Bitto NJ, Chapman R, Pidot S, Costin A, Lo C, Choi J, D'Cruze T, Reynolds EC, Dashper SG, Turnbull L, Whitchurch CB, Stinear TP, Stacey KJ, Ferrero RL.

Sci Rep. 2017 Aug 1;7(1):7072. doi: 10.1038/s41598-017-07288-4.


Effect of azithromycin on a red complex polymicrobial biofilm.

Ong HS, Oettinger-Barak O, Dashper SG, Darby IB, Tan KH, Reynolds EC.

J Oral Microbiol. 2017 Jun 16;9(1):1339579. doi: 10.1080/20002297.2017.1339579. eCollection 2017.


Type IX secretion: the generation of bacterial cell surface coatings involved in virulence, gliding motility and the degradation of complex biopolymers.

Veith PD, Glew MD, Gorasia DG, Reynolds EC.

Mol Microbiol. 2017 Oct;106(1):35-53. doi: 10.1111/mmi.13752. Epub 2017 Aug 9. Review.


Adolescent sympathetic activity and salivary C-reactive protein: The effects of parental behavior.

Nelson BW, Byrne ML, Simmons JG, Whittle S, Schwartz OS, Reynolds EC, O'Brien-Simpson NM, Sheeber L, Allen NB.

Health Psychol. 2017 Oct;36(10):955-965. doi: 10.1037/hea0000516. Epub 2017 Jun 22.


Porphyromonas gulae Activates Unprimed and Gamma Interferon-Primed Macrophages via the Pattern Recognition Receptors Toll-Like Receptor 2 (TLR2), TLR4, and NOD2.

Holden JA, O'Brien-Simpson NM, Lenzo JC, Orth RKH, Mansell A, Reynolds EC.

Infect Immun. 2017 Aug 18;85(9). pii: e00282-17. doi: 10.1128/IAI.00282-17. Print 2017 Sep.


Associations between observed parenting behavior and adolescent inflammation two and a half years later in a community sample.

Byrne ML, Horne S, O'Brien-Simpson NM, Walsh KA, Reynolds EC, Schwartz OS, Whittle S, Simmons JG, Sheeber L, Allen NB.

Health Psychol. 2017 Jul;36(7):641-651. doi: 10.1037/hea0000502. Epub 2017 May 22.


Interferon Regulatory Factor 6 Promotes Keratinocyte Differentiation in Response to Porphyromonas gingivalis.

Huynh J, Scholz GM, Aw J, Reynolds EC.

Infect Immun. 2017 Apr 21;85(5). pii: e00858-16. doi: 10.1128/IAI.00858-16. Print 2017 May.


Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease.

Sanz M, Beighton D, Curtis MA, Cury JA, Dige I, Dommisch H, Ellwood R, Giacaman RA, Herrera D, Herzberg MC, Könönen E, Marsh PD, Meyle J, Mira A, Molina A, Mombelli A, Quirynen M, Reynolds EC, Shapira L, Zaura E.

J Clin Periodontol. 2017 Mar;44 Suppl 18:S5-S11. doi: 10.1111/jcpe.12682.


Porphyromonas gingivalis Uses Specific Domain Rearrangements and Allelic Exchange to Generate Diversity in Surface Virulence Factors.

Dashper SG, Mitchell HL, Seers CA, Gladman SL, Seemann T, Bulach DM, Chandry PS, Cross KJ, Cleal SM, Reynolds EC.

Front Microbiol. 2017 Jan 26;8:48. doi: 10.3389/fmicb.2017.00048. eCollection 2017.


Rapid Chair-Side Test for Detection of Porphyromonas gingivalis.

O'Brien-Simpson NM, Burgess K, Lenzo JC, Brammar GC, Darby IB, Reynolds EC.

J Dent Res. 2017 Jun;96(6):618-625. doi: 10.1177/0022034517691720. Epub 2017 Feb 9.


The Effect of Selective D- or Nα-Methyl Arginine Substitution on the Activity of the Proline-Rich Antimicrobial Peptide, Chex1-Arg20.

Li W, Sun Z, O'Brien-Simpson NM, Otvos L, Reynolds EC, Hossain MA, Separovic F, Wade JD.

Front Chem. 2017 Jan 19;5:1. doi: 10.3389/fchem.2017.00001. eCollection 2017.


Depletion Rate of Hydrogen Peroxide from Sodium Perborate Bleaching Agent.

Tran L, Orth R, Parashos P, Tao Y, Tee CW, Thomas VT, Towers G, Truong DT, Vinen C, Reynolds EC.

J Endod. 2017 Mar;43(3):472-476. doi: 10.1016/j.joen.2016.10.043. Epub 2017 Jan 27.


Food acid content and erosive potential of sugar-free confections.

Shen P, Walker GD, Yuan Y, Reynolds C, Stacey MA, Reynolds EC.

Aust Dent J. 2017 Jun;62(2):215-222. doi: 10.1111/adj.12498. Epub 2017 Apr 19.


Bionano Interaction Study on Antimicrobial Star-Shaped Peptide Polymer Nanoparticles.

Lam SJ, Wong EH, O'Brien-Simpson NM, Pantarat N, Blencowe A, Reynolds EC, Qiao GG.

ACS Appl Mater Interfaces. 2016 Dec 14;8(49):33446-33456. Epub 2016 Nov 29.


C-Terminal Modification and Multimerization Increase the Efficacy of a Proline-Rich Antimicrobial Peptide.

Li W, O'Brien-Simpson NM, Yao S, Tailhades J, Reynolds EC, Dawson RM, Otvos L Jr, Hossain MA, Separovic F, Wade JD.

Chemistry. 2017 Jan 5;23(2):390-396. doi: 10.1002/chem.201604172. Epub 2016 Nov 16.


Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers.

Lam SJ, O'Brien-Simpson NM, Pantarat N, Sulistio A, Wong EH, Chen YY, Lenzo JC, Holden JA, Blencowe A, Reynolds EC, Qiao GG.

Nat Microbiol. 2016 Sep 12;1(11):16162. doi: 10.1038/nmicrobiol.2016.162.


PG1058 Is a Novel Multidomain Protein Component of the Bacterial Type IX Secretion System.

Heath JE, Seers CA, Veith PD, Butler CA, Nor Muhammad NA, Chen YY, Slakeski N, Peng B, Zhang L, Dashper SG, Cross KJ, Cleal SM, Moore C, Reynolds EC.

PLoS One. 2016 Oct 6;11(10):e0164313. doi: 10.1371/journal.pone.0164313. eCollection 2016.


A novel regulatory relationship between RIPK4 and ELF3 in keratinocytes.

Scholz GM, Sulaiman NS, Al Baiiaty S, Kwa MQ, Reynolds EC.

Cell Signal. 2016 Dec;28(12):1916-1922. doi: 10.1016/j.cellsig.2016.09.006. Epub 2016 Sep 22.


Dental plaque bacteria with reduced susceptibility to chlorhexidine are multidrug resistant.

Saleem HG, Seers CA, Sabri AN, Reynolds EC.

BMC Microbiol. 2016 Sep 15;16:214. doi: 10.1186/s12866-016-0833-1.


Casein Phosphopeptide-Amorphous Calcium Phosphate Reduces Streptococcus mutans Biofilm Development on Glass Ionomer Cement and Disrupts Established Biofilms.

Dashper SG, Catmull DV, Liu SW, Myroforidis H, Zalizniak I, Palamara JE, Huq NL, Reynolds EC.

PLoS One. 2016 Sep 2;11(9):e0162322. doi: 10.1371/journal.pone.0162322. eCollection 2016.


Structural Insights into the PorK and PorN Components of the Porphyromonas gingivalis Type IX Secretion System.

Gorasia DG, Veith PD, Hanssen EG, Glew MD, Sato K, Yukitake H, Nakayama K, Reynolds EC.

PLoS Pathog. 2016 Aug 10;12(8):e1005820. doi: 10.1371/journal.ppat.1005820. eCollection 2016 Aug.


Candida virulence and ethanol-derived acetaldehyde production in oral cancer and non-cancer subjects.

Alnuaimi AD, Ramdzan AN, Wiesenfeld D, O'Brien-Simpson NM, Kolev SD, Reynolds EC, McCullough MJ.

Oral Dis. 2016 Nov;22(8):805-814. doi: 10.1111/odi.12565. Epub 2016 Sep 13.


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