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Alarmed by misleading interference in free T3 and free T4 assays: a new case of anti-streptavidin antibodies.

Wouters Y, Oosterbos J, Reynaert N, Penders J.

Clin Chem Lab Med. 2019 Oct 12. pii: /j/cclm.ahead-of-print/cclm-2019-0845/cclm-2019-0845.xml. doi: 10.1515/cclm-2019-0845. [Epub ahead of print] No abstract available.


Cell Type- and Exposure-Specific Modulation of CD63/CD81-Positive and Tissue Factor-Positive Extracellular Vesicle Release in response to Respiratory Toxicants.

Stassen FRM, van Eijck PH, Savelkoul PHM, Wouters EFM, Rohde GGU, Briedé JJ, Reynaert NL, de Kok TM, Benedikter BJ.

Oxid Med Cell Longev. 2019 Aug 14;2019:5204218. doi: 10.1155/2019/5204218. eCollection 2019.


PET and MRI based RT treatment planning: Handling uncertainties.

Reynaert N.

Cancer Radiother. 2019 Oct;23(6-7):753-760. doi: 10.1016/j.canrad.2019.08.002. Epub 2019 Aug 16. Review.


Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease.

Piscaer I, van den Ouweland JMW, Vermeersch K, Reynaert NL, Franssen FME, Keene S, Wouters EFM, Janssens W, Vermeer C, Janssen R.

J Clin Med. 2019 Jul 27;8(8). pii: E1116. doi: 10.3390/jcm8081116.


Personalised radioembolization improves outcomes in refractory intra-hepatic cholangiocarcinoma: a multicenter study.

Levillain H, Duran Derijckere I, Ameye L, Guiot T, Braat A, Meyer C, Vanderlinden B, Reynaert N, Hendlisz A, Lam M, Deroose CM, Ahmadzadehfar H, Flamen P.

Eur J Nucl Med Mol Imaging. 2019 Oct;46(11):2270-2279. doi: 10.1007/s00259-019-04427-z. Epub 2019 Jul 19.


[Radiotherapy treatment planning of prostate cancer using magnetic resonance imaging].

Vanquin L, Boydev C, Korhonen J, Rault E, Crop F, Lacornerie T, Wagner A, Laffarguette J, Pasquier D, Reynaert N.

Cancer Radiother. 2019 Jul;23(4):281-289. doi: 10.1016/j.canrad.2018.09.005. French.


Disease-Specific Comorbidity Clusters in COPD and Accelerated Aging.

Triest FJJ, Franssen FME, Reynaert N, Gaffron S, Spruit MA, Janssen DJA, Rutten EPA, Wouters EFM, Vanfleteren LEGW.

J Clin Med. 2019 Apr 14;8(4). pii: E511. doi: 10.3390/jcm8040511.


3D Monte Carlo dosimetry of intraoperative electron radiation therapy (IOERT).

Alhamada H, Simon S, Philippson C, Vandekerkhove C, Jourani Y, Pauly N, VanGestel D, Reynaert N.

Phys Med. 2019 Jan;57:207-214. doi: 10.1016/j.ejmp.2018.12.037. Epub 2019 Jan 15.


A dosimetry procedure for organs-at-risk in 177Lu peptide receptor radionuclide therapy of patients with neuroendocrine tumours.

Marin G, Vanderlinden B, Karfis I, Guiot T, Wimana Z, Reynaert N, Vandenberghe S, Flamen P.

Phys Med. 2018 Dec;56:41-49. doi: 10.1016/j.ejmp.2018.11.001. Epub 2018 Nov 22.


Shielding disk position in intra-operative electron radiotherapy (IOERT): A Monte Carlo study.

Alhamada H, Simon S, Philippson C, Vandekerkhove C, Jourani Y, Pauly N, Dubus A, Reynaert N.

Phys Med. 2018 Jul;51:1-6. doi: 10.1016/j.ejmp.2018.05.023. Epub 2018 Jun 15.


Evolution of body mass index in children with type 1 diabetes mellitus.

De Keukelaere M, Fieuws S, Reynaert N, Vandoorne E, Kerckhove KV, Asscherickx W, Casteels K.

Eur J Pediatr. 2018 Nov;177(11):1661-1666. doi: 10.1007/s00431-018-3224-9. Epub 2018 Aug 9.


90Y-PET/CT-based dosimetry after selective internal radiation therapy predicts outcome in patients with liver metastases from colorectal cancer.

Levillain H, Duran Derijckere I, Marin G, Guiot T, Vouche M, Reynaert N, Hendlisz A, Vanderlinden B, Flamen P.

EJNMMI Res. 2018 Jul 13;8(1):60. doi: 10.1186/s13550-018-0419-z.


Diffusion weighted MRI as an early predictor of tumor response to hypofractionated stereotactic boost for prostate cancer.

Pasquier D, Hadj Henni A, Escande A, Tresch E, Reynaert N, Colot O, Lartigau E, Betrouni N.

Sci Rep. 2018 Jul 10;8(1):10407. doi: 10.1038/s41598-018-28817-9.


Growth Failure in Children with Systemic Juvenile Idiopathic Arthritis and Prolonged Inflammation despite Treatment with Biologicals: Late Normalization of Height by Combined Hormonal Therapies.

de Zegher F, Reynaert N, De Somer L, Wouters C, Roelants M.

Horm Res Paediatr. 2018;90(5):337-343. doi: 10.1159/000489778. Epub 2018 Jun 25.


Adult Height after Growth Hormone Treatment at Pubertal Onset in Short Adolescents Born Small for Gestational Age: Results from a Belgian Registry-Based Study.

Thomas M, Beckers D, Brachet C, Dotremont H, Lebrethon MC, Lysy P, Massa G, Reynaert N, Rooman R, van der Straaten S, Roelants M, De Schepper J.

Int J Endocrinol. 2018 Apr 3;2018:6421243. doi: 10.1155/2018/6421243. eCollection 2018.


Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells.

Perkins TN, Peeters PM, Albrecht C, Schins RPF, Dentener MA, Mossman BT, Wouters EFM, Reynaert NL.

Toxicol Appl Pharmacol. 2018 Jun 1;348:43-53. doi: 10.1016/j.taap.2018.04.011. Epub 2018 Apr 17.


Abstract ID: 222 Clinical implementation of a Monte Carlo based QA platform for validation of Tomotherapy and Cyberknife treatment plans.

Wagner A, Jourani Y, Crop F, Lacornerie T, Dubus F, Rault E, Comte P, Laffarguette J, Sarrazin T, Reynaert N.

Phys Med. 2018 Jan;45 Suppl 1:S3-S4. doi: 10.1016/j.ejmp.2017.11.030.


Use of an in-house Monte Carlo platform to assess the clinical impact of algorithm-related dose differences on DVH constraints.

Wagner A, Crop F, Mirabel X, Tailly C, Reynaert N.

Phys Med. 2017 Oct;42:319-326. doi: 10.1016/j.ejmp.2017.05.062. Epub 2017 Jun 26.


Zero echo time MRI-only treatment planning for radiation therapy of brain tumors after resection.

Boydev C, Demol B, Pasquier D, Saint-Jalmes H, Delpon G, Reynaert N.

Phys Med. 2017 Oct;42:332-338. doi: 10.1016/j.ejmp.2017.04.028. Epub 2017 May 16.


About the non-consistency of PTV-based prescription in lung.

Lebredonchel S, Lacornerie T, Rault E, Wagner A, Reynaert N, Crop F.

Phys Med. 2017 Dec;44:177-187. doi: 10.1016/j.ejmp.2017.03.009. Epub 2017 Mar 30.


Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants.

Benedikter BJ, Volgers C, van Eijck PH, Wouters EFM, Savelkoul PHM, Reynaert NL, Haenen GRMM, Rohde GGU, Weseler AR, Stassen FRM.

Free Radic Biol Med. 2017 Jul;108:334-344. doi: 10.1016/j.freeradbiomed.2017.03.026. Epub 2017 Mar 28.


Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease.

Konings GFJ, Reynaert NL, Delvoux B, Verhamme FM, Bracke KR, Brusselle GG, Romano A, Vernooy JHJ.

Mol Cell Endocrinol. 2017 Mar 5;443:23-31. doi: 10.1016/j.mce.2016.12.001. Epub 2016 Dec 8.


Involvement of c-Jun N-Terminal Kinase in TNF-α-Driven Remodeling.

Eurlings IM, Reynaert NL, van de Wetering C, Aesif SW, Mercken EM, de Cabo R, van der Velden JL, Janssen-Heininger YM, Wouters EF, Dentener MA.

Am J Respir Cell Mol Biol. 2017 Mar;56(3):393-401. doi: 10.1165/rcmb.2015-0195OC.


Clinical implementation of a Monte Carlo based treatment plan QA platform for validation of Cyberknife and Tomotherapy treatments.

Reynaert N, Demol B, Charoy M, Bouchoucha S, Crop F, Wagner A, Lacornerie T, Dubus F, Rault E, Comte P, Cayez R, Boydev C, Pasquier D, Mirabel X, Lartigau E, Sarrazin T.

Phys Med. 2016 Oct;32(10):1225-1237. doi: 10.1016/j.ejmp.2016.09.009. Epub 2016 Sep 19.


Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease.

Reynaert NL, Gopal P, Rutten EPA, Wouters EFM, Schalkwijk CG.

Int J Biochem Cell Biol. 2016 Dec;81(Pt B):403-418. doi: 10.1016/j.biocel.2016.06.016. Epub 2016 Jun 29. Review.


Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells.

Perkins TN, Dentener MA, Stassen FR, Rohde GG, Mossman BT, Wouters EF, Reynaert NL.

Toxicol Appl Pharmacol. 2016 Jun 15;301:61-70. doi: 10.1016/j.taap.2016.04.003. Epub 2016 Apr 16.


Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice.

Hoffman SM, Qian X, Nolin JD, Chapman DG, Chia SB, Lahue KG, Schneider R, Ather JL, Randall MJ, McMillan DH, Jones JT, Taatjes DJ, Aliyeva M, Daphtary N, Abdalla S, Lundblad LK, Ho YS, Anathy V, Irvin CG, Wouters EF, Reynaert NL, Dixon AE, van der Vliet A, Poynter ME, Janssen-Heininger YM.

Am J Respir Cell Mol Biol. 2016 Sep;55(3):377-86. doi: 10.1165/rcmb.2015-0401OC.


Accelerated partial breast irradiation using robotic radiotherapy: a dosimetric comparison with tomotherapy and three-dimensional conformal radiotherapy.

Rault E, Lacornerie T, Dang HP, Crop F, Lartigau E, Reynaert N, Pasquier D.

Radiat Oncol. 2016 Feb 27;11:29. doi: 10.1186/s13014-016-0607-9.


Expanding the CHARGE Geno-Phenotype: A Girl with Novel CHD7 Deletion, Hypogonadotropic Hypogonadism, and Agenesis of Uterus and Ovaries.

Reynaert N, de Zegher F, Francois I, Devriendt K, Beckers D, Casteels K.

Horm Res Paediatr. 2016;85(4):288-90. doi: 10.1159/000443308. Epub 2016 Jan 8.


Monte Carlo calculation based on hydrogen composition of the tissue for MV photon radiotherapy.

Demol B, Viard R, Reynaert N.

J Appl Clin Med Phys. 2015 Sep 8;16(5):117–130. doi: 10.1120/jacmp.v16i5.5586.


Selective IL-1α exposure to the fetal gut, lung, and chorioamnion/skin causes intestinal inflammatory and developmental changes in fetal sheep.

Nikiforou M, Kemp MW, van Gorp RH, Saito M, Newnham JP, Reynaert NL, Janssen LE, Jobe AH, Kallapur SG, Kramer BW, Wolfs TG.

Lab Invest. 2016 Jan;96(1):69-80. doi: 10.1038/labinvest.2015.127. Epub 2015 Oct 26.


Immune Homeostasis in Epithelial Cells: Evidence and Role of Inflammasome Signaling Reviewed.

Peeters PM, Wouters EF, Reynaert NL.

J Immunol Res. 2015;2015:828264. doi: 10.1155/2015/828264. Epub 2015 Aug 19. Review.


Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease.

Vanhove W, Peeters PM, Staelens D, Schraenen A, Van der Goten J, Cleynen I, De Schepper S, Van Lommel L, Reynaert NL, Schuit F, Van Assche G, Ferrante M, De Hertogh G, Wouters EF, Rutgeerts P, Vermeire S, Nys K, Arijs I.

Inflamm Bowel Dis. 2015 Nov;21(11):2673-82. doi: 10.1097/MIB.0000000000000535.


Adapted Prescription Dose for Monte Carlo Algorithm in Lung SBRT: Clinical Outcome on 205 Patients.

Bibault JE, Mirabel X, Lacornerie T, Tresch E, Reynaert N, Lartigau E.

PLoS One. 2015 Jul 24;10(7):e0133617. doi: 10.1371/journal.pone.0133617. eCollection 2015.


Generation of Viable Plant-Vertebrate Chimeras.

Alvarez M, Reynaert N, Chávez MN, Aedo G, Araya F, Hopfner U, Fernández J, Allende ML, Egaña JT.

PLoS One. 2015 Jun 30;10(6):e0130295. doi: 10.1371/journal.pone.0130295. eCollection 2015.


Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD.

Rutten EP, Gopal P, Wouters EF, Franssen FM, Hageman GJ, Vanfleteren LE, Spruit MA, Reynaert NL.

Chest. 2016 Jan;149(1):53-61. doi: 10.1378/chest.15-0645. Epub 2016 Jan 6.


Registration by interactive inverse simulation: application for adaptive radiotherapy.

Coevoet E, Reynaert N, Lartigau E, Schiappacasse L, Dequidt J, Duriez C.

Int J Comput Assist Radiol Surg. 2015 Aug;10(8):1193-200. doi: 10.1007/s11548-015-1175-4. Epub 2015 Apr 7.


Short Stature in KBG Syndrome: First Responses to Growth Hormone Treatment.

Reynaert N, Ockeloen CW, Sävendahl L, Beckers D, Devriendt K, Kleefstra T, Carels CE, Grigelioniene G, Nordgren A, Francois I, de Zegher F, Casteels K.

Horm Res Paediatr. 2015;83(5):361-4. doi: 10.1159/000380908. Epub 2015 Apr 1.


Congenital nystagmus and central hypothyroidism.

Reynaert N, Braat E, de Zegher F.

Int J Pediatr Endocrinol. 2015;2015(1):7. doi: 10.1186/s13633-015-0003-5. Epub 2015 Mar 16.


What is the normal tissues morbidity following Helical Intensity Modulated Radiation Treatment for cervical cancer?

Mouttet-Audouard R, Lacornerie T, Tresch E, Kramar A, Le Tinier F, Reynaert N, Leblanc E, Narducci F, Lartigau E, Nickers P.

Radiother Oncol. 2015 Jun;115(3):386-91. doi: 10.1016/j.radonc.2015.02.010. Epub 2015 Mar 4.


Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice.

Gopal P, Gosker HR, Theije CC, Eurlings IM, Sell DR, Monnier VM, Reynaert NL.

Biochim Biophys Acta. 2015 May;1852(5):992-1000. doi: 10.1016/j.bbadis.2015.02.003. Epub 2015 Feb 19.


Thiol redox chemistry: role of protein cysteine oxidation and altered redox homeostasis in allergic inflammation and asthma.

Hoffman S, Nolin J, McMillan D, Wouters E, Janssen-Heininger Y, Reynaert N.

J Cell Biochem. 2015 Jun;116(6):884-92. doi: 10.1002/jcb.25017. Review.


The effects of dexamethasone and oxygen in ventilated adult sheep with early phase acute respiratory distress syndrome.

Engel M, Nowacki RM, Boden P, Reiss LK, Uhlig S, Reynaert NL, Gopal P, Wouters EF, Willems CH, Kloosterboer N, Wolfs TG, Zimmermann LJ, Vos GD, Kramer BW.

Lung. 2015 Feb;193(1):97-103. doi: 10.1007/s00408-014-9670-x. Epub 2014 Dec 13.


Introducing interactive inverse FEM simulation and its application for adaptive radiotherapy.

Coevoet E, Reynaert N, Lartigau E, Schiappacasse L, Dequidt J, Duriez C.

Med Image Comput Comput Assist Interv. 2014;17(Pt 2):81-8.


Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs.

Peeters PM, Eurlings IM, Perkins TN, Wouters EF, Schins RP, Borm PJ, Drommer W, Reynaert NL, Albrecht C.

Part Fibre Toxicol. 2014 Nov 19;11:58. doi: 10.1186/s12989-014-0058-0.


Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells.

Perkins TN, Peeters PM, Shukla A, Arijs I, Dragon J, Wouters EF, Reynaert NL, Mossman BT.

Hum Mol Genet. 2015 Mar 1;24(5):1374-89. doi: 10.1093/hmg/ddu551. Epub 2014 Oct 27.


Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition.

Eurlings IM, Reynaert NL, van den Beucken T, Gosker HR, de Theije CC, Verhamme FM, Bracke KR, Wouters EF, Dentener MA.

PLoS One. 2014 Oct 16;9(10):e107757. doi: 10.1371/journal.pone.0107757. eCollection 2014.


GTV-based prescription in SBRT for lung lesions using advanced dose calculation algorithms.

Lacornerie T, Lisbona A, Mirabel X, Lartigau E, Reynaert N.

Radiat Oncol. 2014 Oct 16;9:223. doi: 10.1186/s13014-014-0223-5.


A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.

Eurlings IM, Dentener MA, Mercken EM, de Cabo R, Bracke KR, Vernooy JH, Wouters EF, Reynaert NL.

Am J Physiol Lung Cell Mol Physiol. 2014 Oct 1;307(7):L557-65. doi: 10.1152/ajplung.00116.2014. Epub 2014 Aug 8.

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