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Items: 1 to 20 of 55

1.

Stem cells in cancer initiation and progression.

Bajaj J, Diaz E, Reya T.

J Cell Biol. 2020 Jan 6;219(1). pii: e201911053. doi: 10.1083/jcb.201911053.

PMID:
31874116
2.

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.

Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T.

Nature. 2019 May;569(7754):131-135. doi: 10.1038/s41586-019-1130-6. Epub 2019 Apr 17.

3.

A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.

Lytle NK, Ferguson LP, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schürch CM, Hamilton M, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec I, Eichmann M, Galván JA, Karamitopoulou E, Gilderman T, Esparza LA, Shima Y, Spahn P, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Han H, Ideker T, Deshpande AJ, Lowy AM, Adams PD, Reya T.

Cell. 2019 Apr 18;177(3):572-586.e22. doi: 10.1016/j.cell.2019.03.010. Epub 2019 Apr 4.

PMID:
30955884
4.

Stem cell fate in cancer growth, progression and therapy resistance.

Lytle NK, Barber AG, Reya T.

Nat Rev Cancer. 2018 Nov;18(11):669-680. doi: 10.1038/s41568-018-0056-x. Review.

PMID:
30228301
5.

Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity.

Dravis C, Chung CY, Lytle NK, Herrera-Valdez J, Luna G, Trejo CL, Reya T, Wahl GM.

Cancer Cell. 2018 Sep 10;34(3):466-482.e6. doi: 10.1016/j.ccell.2018.08.001. Epub 2018 Aug 30.

6.

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle NK, Dhar D, Banerjee S, Fagman JB, Browne CD, Umemura A, Valasek MA, Kessler H, Tarin D, Goggins M, Reya T, Diaz-Meco M, Moscat J, Karin M.

Cancer Cell. 2017 Dec 11;32(6):824-839.e8. doi: 10.1016/j.ccell.2017.10.011. Epub 2017 Nov 16.

7.

Glucose feeds the TCA cycle via circulating lactate.

Hui S, Ghergurovich JM, Morscher RJ, Jang C, Teng X, Lu W, Esparza LA, Reya T, Le Zhan, Yanxiang Guo J, White E, Rabinowitz JD.

Nature. 2017 Nov 2;551(7678):115-118. doi: 10.1038/nature24057. Epub 2017 Oct 18.

8.

CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia.

Bajaj J, Konuma T, Lytle NK, Kwon HY, Ablack JN, Cantor JM, Rizzieri D, Chuah C, Oehler VG, Broome EH, Ball ED, van der Horst EH, Ginsberg MH, Reya T.

Cancer Cell. 2016 Nov 14;30(5):792-805. doi: 10.1016/j.ccell.2016.10.003. Epub 2016 Oct 27.

9.

High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo.

Koechlein CS, Harris JR, Lee TK, Weeks J, Fox RG, Zimdahl B, Ito T, Blevins A, Jung SH, Chute JP, Chourasia A, Covert MW, Reya T.

Nat Commun. 2016 Jul 18;7:12169. doi: 10.1038/ncomms12169.

10.

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.

Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp J, Kritzik M, Sicklick J, Sander M, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek M, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod AR, Lowy AM, Reya T.

Nature. 2016 Jun 16;534(7607):407-411. doi: 10.1038/nature17988. Epub 2016 Jun 6.

11.

Delayed Onset of Symptoms Through Feedback Interference in Chronic Cancers.

Haney S, Reya T, Bazhenov M.

Converg Sci Phys Oncol. 2016;2(4). pii: 045002. doi: 10.1088/2057-1739/2/4/045002. Epub 2016 Oct 21.

12.

Musashi signaling in stem cells and cancer.

Fox RG, Park FD, Koechlein CS, Kritzik M, Reya T.

Annu Rev Cell Dev Biol. 2015;31:249-67. doi: 10.1146/annurev-cellbio-100814-125446. Review.

PMID:
26566113
13.

Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia.

Kwon HY, Bajaj J, Ito T, Blevins A, Konuma T, Weeks J, Lytle NK, Koechlein CS, Rizzieri D, Chuah C, Oehler VG, Sasik R, Hardiman G, Reya T.

Cell Stem Cell. 2015 Aug 6;17(2):152-164. doi: 10.1016/j.stem.2015.06.006. Epub 2015 Jul 23.

14.

GLI2 inhibition abrogates human leukemia stem cell dormancy.

Sadarangani A, Pineda G, Lennon KM, Chun HJ, Shih A, Schairer AE, Court AC, Goff DJ, Prashad SL, Geron I, Wall R, McPherson JD, Moore RA, Pu M, Bao L, Jackson-Fisher A, Munchhof M, VanArsdale T, Reya T, Morris SR, Minden MD, Messer K, Mikkola HK, Marra MA, Hudson TJ, Jamieson CH.

J Transl Med. 2015 Mar 21;13:98. doi: 10.1186/s12967-015-0453-9.

15.

Fearful symmetry: subversion of asymmetric division in cancer development and progression.

Bajaj J, Zimdahl B, Reya T.

Cancer Res. 2015 Mar 1;75(5):792-7. doi: 10.1158/0008-5472.CAN-14-2750. Epub 2015 Feb 13. Review. Erratum in: Cancer Res. 2015 Apr 15;75(8):1770.

16.

Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.

Wu X, Zhang W, Font-Burgada J, Palmer T, Hamil AS, Biswas SK, Poidinger M, Borcherding N, Xie Q, Ellies LG, Lytle NK, Wu LW, Fox RG, Yang J, Dowdy SF, Reya T, Karin M.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13870-5. doi: 10.1073/pnas.1414358111. Epub 2014 Sep 4.

17.

Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration.

Lento W, Ito T, Zhao C, Harris JR, Huang W, Jiang C, Owzar K, Piryani S, Racioppi L, Chao N, Reya T.

Genes Dev. 2014 May 1;28(9):995-1004. doi: 10.1101/gad.231944.113.

18.

Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia.

Zimdahl B, Ito T, Blevins A, Bajaj J, Konuma T, Weeks J, Koechlein CS, Kwon HY, Arami O, Rizzieri D, Broome HE, Chuah C, Oehler VG, Sasik R, Hardiman G, Reya T.

Nat Genet. 2014 Mar;46(3):245-52. doi: 10.1038/ng.2889. Epub 2014 Feb 2.

19.

Wnt signaling in normal and malignant hematopoiesis.

Lento W, Congdon K, Voermans C, Kritzik M, Reya T.

Cold Spring Harb Perspect Biol. 2013 Feb 1;5(2). pii: a008011. doi: 10.1101/cshperspect.a008011. Review.

20.

Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.

Kurokawa M, Ito T, Yang CS, Zhao C, Macintyre AN, Rizzieri DA, Rathmell JC, Deininger MW, Reya T, Kornbluth S.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2300-5. doi: 10.1073/pnas.1206551110. Epub 2013 Jan 16.

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