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Items: 1 to 50 of 108

1.

Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA(s).

Garbuzenko OB, Ivanova V, Kholodovych V, Reimer DC, Reuhl KR, Yurkow E, Adler D, Minko T.

Nanomedicine. 2017 Aug;13(6):1983-1992. doi: 10.1016/j.nano.2017.04.005. Epub 2017 Apr 19.

2.

Trimethyltin intoxication induces the migration of ventricular/subventricular zone cells to the injured murine hippocampus.

Weig BC, Richardson JR, Lowndes HE, Reuhl KR.

Neurotoxicology. 2016 May;54:72-80. doi: 10.1016/j.neuro.2016.03.023. Epub 2016 Apr 1.

PMID:
27045884
3.

Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells.

Teh JL, Shah R, La Cava S, Dolfi SC, Mehta MS, Kongara S, Price S, Ganesan S, Reuhl KR, Hirshfield KM, Karantza V, Chen S.

Breast Cancer Res Treat. 2015 May;151(1):57-73. doi: 10.1007/s10549-015-3365-8. Epub 2015 Apr 10.

4.

Novel cystine ester mimics for the treatment of cystinuria-induced urolithiasis in a knockout mouse model.

Sahota A, Parihar JS, Capaccione KM, Yang M, Noll K, Gordon D, Reimer D, Yang I, Buckley BT, Polunas M, Reuhl KR, Lewis MR, Ward MD, Goldfarb DS, Tischfield JA.

Urology. 2014 Nov;84(5):1249.e9-15. doi: 10.1016/j.urology.2014.07.043. Epub 2014 Oct 24.

5.

Effective intravenous therapy for neurodegenerative disease with a therapeutic enzyme and a peptide that mediates delivery to the brain.

Meng Y, Sohar I, Sleat DE, Richardson JR, Reuhl KR, Jenkins RB, Sarkar G, Lobel P.

Mol Ther. 2014 Mar;22(3):547-553. doi: 10.1038/mt.2013.267. Epub 2013 Dec 26.

6.

U1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In Vivo.

Goraczniak R, Wall BA, Behlke MA, Lennox KA, Ho ES, Zaphiros NH, Jakubowski C, Patel NR, Zhao S, Magaway C, Subbie SA, Jenny Yu L, Lacava S, Reuhl KR, Chen S, Gunderson SI.

Mol Ther Nucleic Acids. 2013 May 14;2:e92. doi: 10.1038/mtna.2013.24.

7.

Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a,h]anthracene.

Chang RL, Wood AW, Huang MT, Xie JG, Cui XX, Reuhl KR, Boyd DR, Lin Y, Shih WJ, Balani SK, Yagi H, Jerina DM, Conney AH.

Carcinogenesis. 2013 Sep;34(9):2184-91. doi: 10.1093/carcin/bgt164. Epub 2013 May 13.

8.

Inhalation treatment of pulmonary fibrosis by liposomal prostaglandin E2.

Ivanova V, Garbuzenko OB, Reuhl KR, Reimer DC, Pozharov VP, Minko T.

Eur J Pharm Biopharm. 2013 Jun;84(2):335-44. doi: 10.1016/j.ejpb.2012.11.023. Epub 2012 Dec 8.

9.

Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.

Li G, Wang H, Liu AB, Cheung C, Reuhl KR, Bosland MC, Yang CS.

Cancer Prev Res (Phila). 2012 Jul;5(7):963-72. doi: 10.1158/1940-6207.CAPR-12-0023. Epub 2012 May 11.

10.

Two-in-one: combined targeted chemo and gene therapy for tumor suppression and prevention of metastases.

Zhang M, Garbuzenko OB, Reuhl KR, Rodriguez-Rodriguez L, Minko T.

Nanomedicine (Lond). 2012 Feb;7(2):185-97. doi: 10.2217/nnm.11.131.

PMID:
22339132
11.

Polychlorinated biphenyl congeners that increase the glucuronidation and biliary excretion of thyroxine are distinct from the congeners that enhance the serum disappearance of thyroxine.

Martin LA, Wilson DT, Reuhl KR, Gallo MA, Klaassen CD.

Drug Metab Dispos. 2012 Mar;40(3):588-95. doi: 10.1124/dmd.111.042796. Epub 2011 Dec 20.

12.
13.

Effects of green tea polyphenol (-)-epigallocatechin-3-gallate on newly developed high-fat/Western-style diet-induced obesity and metabolic syndrome in mice.

Chen YK, Cheung C, Reuhl KR, Liu AB, Lee MJ, Lu YP, Yang CS.

J Agric Food Chem. 2011 Nov 9;59(21):11862-71. doi: 10.1021/jf2029016. Epub 2011 Oct 18.

14.

Transplantation of ╬▓-endorphin neurons into the hypothalamus promotes immune function and restricts the growth and metastasis of mammary carcinoma.

Sarkar DK, Zhang C, Murugan S, Dokur M, Boyadjieva NI, Ortig├╝ela M, Reuhl KR, Mojtehedzadeh S.

Cancer Res. 2011 Oct 1;71(19):6282-91. doi: 10.1158/0008-5472.CAN-11-1610. Epub 2011 Aug 11.

15.

Fetal alcohol exposure increases mammary tumor susceptibility and alters tumor phenotype in rats.

Polanco TA, Crismale-Gann C, Reuhl KR, Sarkar DK, Cohick WS.

Alcohol Clin Exp Res. 2010 Nov;34(11):1879-87. doi: 10.1111/j.1530-0277.2010.01276.x.

16.

Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance.

Garbuzenko OB, Saad M, Pozharov VP, Reuhl KR, Mainelis G, Minko T.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10737-42. doi: 10.1073/pnas.1004604107. Epub 2010 May 24.

17.

Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice.

Lambert JD, Kennett MJ, Sang S, Reuhl KR, Ju J, Yang CS.

Food Chem Toxicol. 2010 Jan;48(1):409-16. doi: 10.1016/j.fct.2009.10.030. Epub 2009 Oct 31.

18.

Effect of alpha-tocopherol, N-acetylcysteine and omeprazole on esophageal adenocarcinoma formation in a rat surgical model.

Hao J, Zhang B, Liu B, Lee M, Hao X, Reuhl KR, Chen X, Yang CS.

Int J Cancer. 2009 Mar 15;124(6):1270-5. doi: 10.1002/ijc.24077.

19.
20.

VPA-induced apoptosis and behavioral deficits in neonatal mice.

Yochum CL, Dowling P, Reuhl KR, Wagner GC, Ming X.

Brain Res. 2008 Apr 8;1203:126-32. doi: 10.1016/j.brainres.2008.01.055. Epub 2008 Feb 5.

PMID:
18316065
21.

Dietary clofibrate stimulates the formation and size of estradiol-induced breast tumors in female August-Copenhagen Irish (ACI) rats.

Mesia-Vela S, Sanchez RI, Roberts KG, Reuhl KR, Conney AH, Kauffman FC.

Toxicology. 2008 Apr 3;246(1):63-72. doi: 10.1016/j.tox.2007.12.025. Epub 2008 Jan 6.

23.

Methylmercury elicits rapid inhibition of cell proliferation in the developing brain and decreases cell cycle regulator, cyclin E.

Burke K, Cheng Y, Li B, Petrov A, Joshi P, Berman RF, Reuhl KR, DiCicco-Bloom E.

Neurotoxicology. 2006 Dec;27(6):970-81. Epub 2006 Sep 15.

24.

Behavioral and neurochemical sensitization to amphetamine following early postnatal administration of methylmercury (MeHg).

Wagner GC, Reuhl KR, Ming X, Halladay AK.

Neurotoxicology. 2007 Jan;28(1):59-66. Epub 2006 Jul 21.

PMID:
16942796
25.

CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody.

Zhu LR, Thomas PE, Lu G, Reuhl KR, Yang GY, Wang LD, Wang SL, Yang CS, He XY, Hong JY.

Drug Metab Dispos. 2006 Oct;34(10):1672-6. Epub 2006 Jun 30.

PMID:
16815959
26.

A new neurobehavioral model of autism in mice: pre- and postnatal exposure to sodium valproate.

Wagner GC, Reuhl KR, Cheh M, McRae P, Halladay AK.

J Autism Dev Disord. 2006 Aug;36(6):779-93.

PMID:
16609825
27.

Trimethyltin-induced alterations in behavior are linked to changes in PSA-NCAM expression.

Halladay AK, Wilson DT, Wagner GC, Reuhl KR.

Neurotoxicology. 2006 Mar;27(2):137-46. Epub 2006 Jan 19.

PMID:
16426681
28.

Phenobarbital treatment inhibits the formation of estradiol-dependent mammary tumors in the August-Copenhagen Irish rat.

Mesia-Vela S, Sanchez RI, Reuhl KR, Conney AH, Kauffman FC.

J Pharmacol Exp Ther. 2006 May;317(2):590-7. Epub 2006 Jan 18.

PMID:
16421288
29.

Methylmercury alters Eph and ephrin expression during neuronal differentiation of P19 embryonal carcinoma cells.

Wilson DT, Polunas MA, Zhou R, Halladay AK, Lowndes HE, Reuhl KR.

Neurotoxicology. 2005 Aug;26(4):661-74.

PMID:
15990172
30.

The effects of steroidal estrogens in ACI rat mammary carcinogenesis: 17beta-estradiol, 2-hydroxyestradiol, 4-hydroxyestradiol, 16alpha-hydroxyestradiol, and 4-hydroxyestrone.

Turan VK, Sanchez RI, Li JJ, Li SA, Reuhl KR, Thomas PE, Conney AH, Gallo MA, Kauffman FC, Mesia-Vela S.

J Endocrinol. 2004 Oct;183(1):91-9.

PMID:
15525577
31.

Dietary clofibrate inhibits induction of hepatic antioxidant enzymes by chronic estradiol in female ACI rats.

Mesia-Vela S, Sanchez RI, Reuhl KR, Conney AH, Kauffman FC.

Toxicology. 2004 Aug 5;200(2-3):103-11.

PMID:
15212807
32.

Constitutive and inducible levels of CYP1A1 and CYP1A2 in rat cerebral cortex and cerebellum.

Iba MM, Storch A, Ghosal A, Bennett S, Reuhl KR, Lowndes HE.

Arch Toxicol. 2003 Oct;77(10):547-54. Epub 2003 Jul 11.

PMID:
14574441
33.

Effects of mutant ubiquitin on ts1 retrovirus-mediated neuropathology.

Zhang M, Thurig S, Tsirigotis M, Wong PK, Reuhl KR, Gray DA.

J Virol. 2003 Jul;77(13):7193-201.

34.

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.

Pollock PM, Cohen-Solal K, Sood R, Namkoong J, Martino JJ, Koganti A, Zhu H, Robbins C, Makalowska I, Shin SS, Marin Y, Roberts KG, Yudt LM, Chen A, Cheng J, Incao A, Pinkett HW, Graham CL, Dunn K, Crespo-Carbone SM, Mackason KR, Ryan KB, Sinsimer D, Goydos J, Reuhl KR, Eckhaus M, Meltzer PS, Pavan WJ, Trent JM, Chen S.

Nat Genet. 2003 May;34(1):108-12.

PMID:
12704387
35.

Glutathione peroxidase inhibits cell death and glial activation following experimental stroke.

Ishibashi N, Prokopenko O, Weisbrot-Lefkowitz M, Reuhl KR, Mirochnitchenko O.

Brain Res Mol Brain Res. 2002 Dec 30;109(1-2):34-44.

PMID:
12531513
36.

Cadherins and NCAM as potential targets in metal toxicity.

Prozialeck WC, Grunwald GB, Dey PM, Reuhl KR, Parrish AR.

Toxicol Appl Pharmacol. 2002 Aug 1;182(3):255-65. Review.

PMID:
12183105
37.

Progressive appearance of pigmentation in amelanotic melanoma lesions.

Cohen-Solal KA, Crespo-Carbone SM, Namkoong J, Mackason KR, Roberts KG, Reuhl KR, Chen S.

Pigment Cell Res. 2002 Aug;15(4):282-9.

PMID:
12100494
38.

Inflammatory response and glutathione peroxidase in a model of stroke.

Ishibashi N, Prokopenko O, Reuhl KR, Mirochnitchenko O.

J Immunol. 2002 Feb 15;168(4):1926-33.

39.

Development of cutaneous amelanotic melanoma in the absence of a functional tyrosinase.

Cohen-Solal KA, Reuhl KR, Ryan KB, Roberts KG, Chen S.

Pigment Cell Res. 2001 Dec;14(6):466-74.

PMID:
11775059
40.

Delayed expression of the NFH subunit in differentiating P19 cells.

Pyle SJ, Roberts KG, Reuhl KR.

Brain Res Dev Brain Res. 2001 Dec 14;132(1):103-6.

PMID:
11744113
41.

Preferential destruction of cerebellar Purkinje cells by OX7-saporin.

Angner RT, Kelly RM, Wiley RG, Walsh TJ, Reuhl KR.

Neurotoxicology. 2000 Jun;21(3):395-403.

PMID:
10894129
42.

Developmental lead exposure disturbs expression of synaptic neural cell adhesion molecules in herring gull brains.

Dey PM, Burger J, Gochfeld M, Reuhl KR.

Toxicology. 2000 May 5;146(2-3):137-47.

PMID:
10814846
43.

Mechanisms of injury in the central nervous system.

Philbert MA, Billingsley ML, Reuhl KR.

Toxicol Pathol. 2000 Jan-Feb;28(1):43-53. Review.

PMID:
10668990
44.
45.

Development of esophageal metaplasia and adenocarcinoma in a rat surgical model without the use of a carcinogen.

Goldstein SR, Yang GY, Curtis SK, Reuhl KR, Liu BC, Mirvish SS, Newmark HL, Yang CS.

Carcinogenesis. 1997 Nov;18(11):2265-70.

PMID:
9395230
46.

Effects of phenethyl isothiocyanate on acetaminophen metabolism and hepatotoxicity in mice.

Li Y, Wang EJ, Chen L, Stein AP, Reuhl KR, Yang CS.

Toxicol Appl Pharmacol. 1997 Jun;144(2):306-14.

PMID:
9194414
47.

Altered sensitivity of posttranslationally modified microtubules to methylmercury in differentiating embryonal carcinoma-derived neurons.

Graff RD, Falconer MM, Brown DL, Reuhl KR.

Toxicol Appl Pharmacol. 1997 Jun;144(2):215-24.

PMID:
9194405
48.

Altered expression of polysialylated NCAM in mouse hippocampus following trimethyltin administration.

Dey PM, Polunas MA, Philbert MA, Reuhl KR.

Neurotoxicology. 1997;18(3):633-43.

PMID:
9339813
49.

Developmental neurotoxicity of methanol exposure by inhalation in rats.

Weiss B, Stern S, Soderholm SC, Cox C, Sharma A, Inglis GB, Preston R, Balys M, Reuhl KR, Gelein R.

Res Rep Health Eff Inst. 1996 Apr;(73):1-64; discussion 65-70.

PMID:
11379053
50.

Effects of benzene metabolite treatment on granulocytic differentiation and DNA adduct formation in HL-60 cells.

Hedli CC, Rao NR, Reuhl KR, Witmer CM, Snyder R.

Arch Toxicol. 1996;70(3-4):135-44.

PMID:
8825669

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