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Items: 1 to 50 of 174

1.

XX sex chromosome complement promotes atherosclerosis in mice.

AlSiraj Y, Chen X, Thatcher SE, Temel RE, Cai L, Blalock E, Katz W, Ali HM, Petriello M, Deng P, Morris AJ, Wang X, Lusis AJ, Arnold AP, Reue K, Thompson K, Tso P, Cassis LA.

Nat Commun. 2019 Jun 14;10(1):2631. doi: 10.1038/s41467-019-10462-z.

PMID:
31201301
2.

Noggin depletion in adipocytes promotes obesity in mice.

Blázquez-Medela AM, Jumabay M, Rajbhandari P, Sallam T, Guo Y, Yao J, Vergnes L, Reue K, Zhang L, Yao Y, Fogelman AM, Tontonoz P, Lusis AJ, Wu X, Boström KI.

Mol Metab. 2019 Apr 10. pii: S2212-8778(18)31188-8. doi: 10.1016/j.molmet.2019.04.004. [Epub ahead of print]

3.

Mammalian lipin phosphatidic acid phosphatases in lipid synthesis and beyond: metabolic and inflammatory disorders.

Reue K, Wang H.

J Lipid Res. 2019 Apr;60(4):728-733. doi: 10.1194/jlr.S091769. Epub 2019 Feb 25.

PMID:
30804008
4.

PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity.

Shih DM, Meng Y, Sallam T, Vergnes L, Shu ML, Reue K, Tontonoz P, Fogelman AM, Lusis AJ, Reddy ST.

Antioxidants (Basel). 2019 Jan 11;8(1). pii: E19. doi: 10.3390/antiox8010019.

5.

Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits.

Norheim F, Hasin-Brumshtein Y, Vergnes L, Chella Krishnan K, Pan C, Seldin MM, Hui ST, Mehrabian M, Zhou Z, Gupta S, Parks BW, Walch A, Reue K, Hofmann SM, Arnold AP, Lusis AJ.

Cell Metab. 2019 Apr 2;29(4):932-949.e4. doi: 10.1016/j.cmet.2018.12.013. Epub 2019 Jan 10.

PMID:
30639359
6.

Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis.

Zhang P, Csaki LS, Ronquillo E, Baufeld LJ, Lin JY, Gutierrez A, Dwyer JR, Brindley DN, Fong LG, Tontonoz P, Young SG, Reue K.

J Clin Invest. 2019 Jan 2;129(1):281-295. doi: 10.1172/JCI122595. Epub 2018 Dec 3.

7.

Deciphering the Role of Lipid Droplets in Cardiovascular Disease: A Report From the 2017 National Heart, Lung, and Blood Institute Workshop.

Goldberg IJ, Reue K, Abumrad NA, Bickel PE, Cohen S, Fisher EA, Galis ZS, Granneman JG, Lewandowski ED, Murphy R, Olive M, Schaffer JE, Schwartz-Longacre L, Shulman GI, Walther TC, Chen J.

Circulation. 2018 Jul 17;138(3):305-315. doi: 10.1161/CIRCULATIONAHA.118.033704. Review.

PMID:
30012703
8.

KDM4B protects against obesity and metabolic dysfunction.

Cheng Y, Yuan Q, Vergnes L, Rong X, Youn JY, Li J, Yu Y, Liu W, Cai H, Lin JD, Tontonoz P, Hong C, Reue K, Wang CY.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5566-E5575. doi: 10.1073/pnas.1721814115. Epub 2018 May 29. Erratum in: Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2384-2385.

9.

Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.

Li TY, Song L, Sun Y, Li J, Yi C, Lam SM, Xu D, Zhou L, Li X, Yang Y, Zhang CS, Xie C, Huang X, Shui G, Lin SY, Reue K, Lin SC.

Nat Commun. 2018 May 15;9(1):1916. doi: 10.1038/s41467-018-04363-w.

10.

A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism.

Seldin MM, Koplev S, Rajbhandari P, Vergnes L, Rosenberg GM, Meng Y, Pan C, Phuong TMN, Gharakhanian R, Che N, Mäkinen S, Shih DM, Civelek M, Parks BW, Kim ED, Norheim F, Chella Krishnan K, Hasin-Brumshtein Y, Mehrabian M, Laakso M, Drevon CA, Koistinen HA, Tontonoz P, Reue K, Cantor RM, Björkegren JLM, Lusis AJ.

Cell Metab. 2018 May 1;27(5):1138-1155.e6. doi: 10.1016/j.cmet.2018.03.015.

11.

NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes.

He C, Weston TA, Jung RS, Heizer P, Larsson M, Hu X, Allan CM, Tontonoz P, Reue K, Beigneux AP, Ploug M, Holme A, Kilburn M, Guagliardo P, Ford DA, Fong LG, Young SG, Jiang H.

Cell Metab. 2018 May 1;27(5):1055-1066.e3. doi: 10.1016/j.cmet.2018.03.017.

12.

Sex differences in obesity, lipid metabolism, and inflammation-A role for the sex chromosomes?

Zore T, Palafox M, Reue K.

Mol Metab. 2018 Sep;15:35-44. doi: 10.1016/j.molmet.2018.04.003. Epub 2018 Apr 12. Review.

13.

Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells.

Hodeib M, Ogrodzinski MP, Vergnes L, Reue K, Karlan BY, Lunt SY, Aspuria PP.

Oncotarget. 2017 Dec 23;9(3):4044-4060. doi: 10.18632/oncotarget.23661. eCollection 2018 Jan 9.

14.

Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress.

Zhou Z, Ribas V, Rajbhandari P, Drew BG, Moore TM, Fluitt AH, Reddish BR, Whitney KA, Georgia S, Vergnes L, Reue K, Liesa M, Shirihai O, van der Bliek AM, Chi NW, Mahata SK, Tiano JP, Hewitt SC, Tontonoz P, Korach KS, Mauvais-Jarvis F, Hevener AL.

J Biol Chem. 2018 Mar 30;293(13):4735-4751. doi: 10.1074/jbc.M117.805069. Epub 2018 Jan 29.

15.

Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease.

Chella Krishnan K, Kurt Z, Barrere-Cain R, Sabir S, Das A, Floyd R, Vergnes L, Zhao Y, Che N, Charugundla S, Qi H, Zhou Z, Meng Y, Pan C, Seldin MM, Norheim F, Hui S, Reue K, Lusis AJ, Yang X.

Cell Syst. 2018 Jan 24;6(1):103-115.e7. doi: 10.1016/j.cels.2017.12.006. Epub 2018 Jan 18.

16.

Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants.

Lee JM, Ong JR, Vergnes L, de Aguiar Vallim TQ, Nolan J, Cantor RM, Walters JRF, Reue K.

J Lipid Res. 2018 Mar;59(3):429-438. doi: 10.1194/jlr.M078279. Epub 2018 Jan 2.

17.

IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure.

Rajbhandari P, Thomas BJ, Feng AC, Hong C, Wang J, Vergnes L, Sallam T, Wang B, Sandhu J, Seldin MM, Lusis AJ, Fong LG, Katz M, Lee R, Young SG, Reue K, Smale ST, Tontonoz P.

Cell. 2018 Jan 11;172(1-2):218-233.e17. doi: 10.1016/j.cell.2017.11.019. Epub 2017 Dec 14.

18.

Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis.

Nakano H, Minami I, Braas D, Pappoe H, Wu X, Sagadevan A, Vergnes L, Fu K, Morselli M, Dunham C, Ding X, Stieg AZ, Gimzewski JK, Pellegrini M, Clark PM, Reue K, Lusis AJ, Ribalet B, Kurdistani SK, Christofk H, Nakatsuji N, Nakano A.

Elife. 2017 Dec 12;6. pii: e29330. doi: 10.7554/eLife.29330.

19.

How lipid droplets "TAG" along: Glycerolipid synthetic enzymes and lipid storage.

Wang H, Airola MV, Reue K.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt B):1131-1145. doi: 10.1016/j.bbalip.2017.06.010. Epub 2017 Jun 20. Review.

20.

Genetic Basis for Sex Differences in Obesity and Lipid Metabolism.

Link JC, Reue K.

Annu Rev Nutr. 2017 Aug 21;37:225-245. doi: 10.1146/annurev-nutr-071816-064827. Epub 2017 Jun 19. Review.

21.

A Guide for the Design of Pre-clinical Studies on Sex Differences in Metabolism.

Mauvais-Jarvis F, Arnold AP, Reue K.

Cell Metab. 2017 Jun 6;25(6):1216-1230. doi: 10.1016/j.cmet.2017.04.033. Review.

22.

Lipin proteins and glycerolipid metabolism: Roles at the ER membrane and beyond.

Zhang P, Reue K.

Biochim Biophys Acta Biomembr. 2017 Sep;1859(9 Pt B):1583-1595. doi: 10.1016/j.bbamem.2017.04.007. Epub 2017 Apr 11. Review.

23.

Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia.

Beigneux AP, Miyashita K, Ploug M, Blom DJ, Ai M, Linton MF, Khovidhunkit W, Dufour R, Garg A, McMahon MA, Pullinger CR, Sandoval NP, Hu X, Allan CM, Larsson M, Machida T, Murakami M, Reue K, Tontonoz P, Goldberg IJ, Moulin P, Charrière S, Fong LG, Nakajima K, Young SG.

N Engl J Med. 2017 Apr 27;376(17):1647-1658. doi: 10.1056/NEJMoa1611930. Epub 2017 Apr 5.

24.

Sex differences in obesity: X chromosome dosage as a risk factor for increased food intake, adiposity and co-morbidities.

Reue K.

Physiol Behav. 2017 Jul 1;176:174-182. doi: 10.1016/j.physbeh.2017.02.040. Epub 2017 Mar 8. Review.

25.

Sex Hormones and Sex Chromosomes Cause Sex Differences in the Development of Cardiovascular Diseases.

Arnold AP, Cassis LA, Eghbali M, Reue K, Sandberg K.

Arterioscler Thromb Vasc Biol. 2017 May;37(5):746-756. doi: 10.1161/ATVBAHA.116.307301. Epub 2017 Mar 9. Review.

26.

RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs.

Wang J, Rajbhandari P, Damianov A, Han A, Sallam T, Waki H, Villanueva CJ, Lee SD, Nielsen R, Mandrup S, Reue K, Young SG, Whitelegge J, Saez E, Black DL, Tontonoz P.

J Clin Invest. 2017 Mar 1;127(3):987-1004. doi: 10.1172/JCI89484. Epub 2017 Feb 13.

27.

Diet, gonadal sex, and sex chromosome complement influence white adipose tissue miRNA expression.

Link JC, Hasin-Brumshtein Y, Cantor RM, Chen X, Arnold AP, Lusis AJ, Reue K.

BMC Genomics. 2017 Jan 17;18(1):89. doi: 10.1186/s12864-017-3484-1.

28.

Adipocyte Browning and Higher Mitochondrial Function in Periadrenal But Not SC Fat in Pheochromocytoma.

Vergnes L, Davies GR, Lin JY, Yeh MW, Livhits MJ, Harari A, Symonds ME, Sacks HS, Reue K.

J Clin Endocrinol Metab. 2016 Nov;101(11):4440-4448. Epub 2016 Aug 30.

29.

Simulated microgravity enhances oligodendrocyte mitochondrial function and lipid metabolism.

Espinosa-Jeffrey A, Nguyen K, Kumar S, Toshimasa O, Hirose R, Reue K, Vergnes L, Kinchen J, Vellis J.

J Neurosci Res. 2016 Dec;94(12):1434-1450. doi: 10.1002/jnr.23958. Epub 2016 Sep 28.

PMID:
27680492
30.

StarD7 Protein Deficiency Adversely Affects the Phosphatidylcholine Composition, Respiratory Activity, and Cristae Structure of Mitochondria.

Horibata Y, Ando H, Zhang P, Vergnes L, Aoyama C, Itoh M, Reue K, Sugimoto H.

J Biol Chem. 2016 Nov 25;291(48):24880-24891. Epub 2016 Sep 30.

31.

Prdm4 induction by the small molecule butein promotes white adipose tissue browning.

Song NJ, Choi S, Rajbhandari P, Chang SH, Kim S, Vergnes L, Kwon SM, Yoon JH, Lee S, Ku JM, Lee JS, Reue K, Koo SH, Tontonoz P, Park KW.

Nat Chem Biol. 2016 Jul;12(7):479-81. doi: 10.1038/nchembio.2081. Epub 2016 May 9.

32.

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.

Zhang J, Khvorostov I, Hong JS, Oktay Y, Vergnes L, Nuebel E, Wahjudi PN, Setoguchi K, Wang G, Do A, Jung HJ, McCaffery JM, Kurland IJ, Reue K, Lee WN, Koehler CM, Teitell MA.

EMBO J. 2016 Apr 15;35(8):899. doi: 10.15252/embj.201694054. No abstract available.

33.

Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females.

Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL.

Sci Transl Med. 2016 Apr 13;8(334):334ra54. doi: 10.1126/scitranslmed.aad3815.

34.

The importance of having two X chromosomes.

Arnold AP, Reue K, Eghbali M, Vilain E, Chen X, Ghahramani N, Itoh Y, Li J, Link JC, Ngun T, Williams-Burris SM.

Philos Trans R Soc Lond B Biol Sci. 2016 Feb 19;371(1688):20150113. doi: 10.1098/rstb.2015.0113. Epub 2016 Feb 1. Review.

35.

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.

York AG, Williams KJ, Argus JP, Zhou QD, Brar G, Vergnes L, Gray EE, Zhen A, Wu NC, Yamada DH, Cunningham CR, Tarling EJ, Wilks MQ, Casero D, Gray DH, Yu AK, Wang ES, Brooks DG, Sun R, Kitchen SG, Wu TT, Reue K, Stetson DB, Bensinger SJ.

Cell. 2015 Dec 17;163(7):1716-29. doi: 10.1016/j.cell.2015.11.045. Epub 2015 Dec 10.

36.

SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression.

Vergnes L, Chin RG, de Aguiar Vallim T, Fong LG, Osborne TF, Young SG, Reue K.

J Lipid Res. 2016 Mar;57(3):410-21. doi: 10.1194/jlr.M064022. Epub 2015 Dec 18.

37.

Dietary fructose aggravates the pathobiology of traumatic brain injury by influencing energy homeostasis and plasticity.

Agrawal R, Noble E, Vergnes L, Ying Z, Reue K, Gomez-Pinilla F.

J Cereb Blood Flow Metab. 2016 May;36(5):941-53. doi: 10.1177/0271678X15606719. Epub 2015 Oct 1.

38.

Women in Metabolism: Part 3.

Ashcroft F, Pearce E, Partridge L, Suomalainen A, Brunet A, Schulze A, Tseng YH, Sethi JK, Reue K, Kingwell B, McNally E, Cnop M, Hevener AL, Diano S.

Cell Metab. 2015 Dec 1;22(6):949-53. doi: 10.1016/j.cmet.2015.11.005.

39.

ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure.

Dijk W, Heine M, Vergnes L, Boon MR, Schaart G, Hesselink MK, Reue K, van Marken Lichtenbelt WD, Olivecrona G, Rensen PC, Heeren J, Kersten S.

Elife. 2015 Oct 17;4. pii: e08428. doi: 10.7554/eLife.08428.

40.

Increased Expression of Beige/Brown Adipose Markers from Host and Breast Cancer Cells Influence Xenograft Formation in Mice.

Singh R, Parveen M, Basgen JM, Fazel S, Meshesha MF, Thames EC, Moore B, Martinez L, Howard CB, Vergnes L, Reue K, Pervin S.

Mol Cancer Res. 2016 Jan;14(1):78-92. doi: 10.1158/1541-7786.MCR-15-0151. Epub 2015 Oct 13.

41.

Sex differences in diurnal rhythms of food intake in mice caused by gonadal hormones and complement of sex chromosomes.

Chen X, Wang L, Loh DH, Colwell CS, Taché Y, Reue K, Arnold AP.

Horm Behav. 2015 Sep;75:55-63. doi: 10.1016/j.yhbeh.2015.07.020. Epub 2015 Jul 29.

42.

2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling.

Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, Pai MY, Li S, Ta L, Fazlollahi F, Chen C, Prins RM, Teitell MA, Nathanson DA, Lai A, Faull KF, Jiang M, Clarke SG, Cloughesy TF, Graeber TG, Braas D, Christofk HR, Jung ME, Reue K, Huang J.

Cell Metab. 2015 Sep 1;22(3):508-15. doi: 10.1016/j.cmet.2015.06.009. Epub 2015 Jul 16.

43.

Disturbed Flow Induces Autophagy, but Impairs Autophagic Flux to Perturb Mitochondrial Homeostasis.

Li R, Jen N, Wu L, Lee J, Fang K, Quigley K, Lee K, Wang S, Zhou B, Vergnes L, Chen YR, Li Z, Reue K, Ann DK, Hsiai TK.

Antioxid Redox Signal. 2015 Nov 20;23(15):1207-19. doi: 10.1089/ars.2014.5896. Epub 2015 Jun 29.

44.

Increased high-density lipoprotein cholesterol levels in mice with XX versus XY sex chromosomes.

Link JC, Chen X, Prien C, Borja MS, Hammerson B, Oda MN, Arnold AP, Reue K.

Arterioscler Thromb Vasc Biol. 2015 Aug;35(8):1778-86. doi: 10.1161/ATVBAHA.115.305460. Epub 2015 Jun 25.

45.

Diet1 is a regulator of fibroblast growth factor 15/19-dependent bile acid synthesis.

Reue K, Lee JM, Vergnes L.

Dig Dis. 2015;33(3):307-13. doi: 10.1159/000371649. Epub 2015 May 27.

46.

Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism.

Aspuria PP, Lunt SY, Väremo L, Vergnes L, Gozo M, Beach JA, Salumbides B, Reue K, Wiedemeyer WR, Nielsen J, Karlan BY, Orsulic S.

Cancer Metab. 2014 Dec 15;2:21. doi: 10.1186/2049-3002-2-21. eCollection 2014.

47.

Lipin-1 flexes its muscle in autophagy.

Zhang P, Reue K.

Cell Cycle. 2014;13(24):3789-90. doi: 10.4161/15384101.2014.988105. No abstract available.

48.

PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis.

Shih DM, Yu JM, Vergnes L, Dali-Youcef N, Champion MD, Devarajan A, Zhang P, Castellani LW, Brindley DN, Jamey C, Auwerx J, Reddy ST, Ford DA, Reue K, Lusis AJ.

FASEB J. 2015 Apr;29(4):1185-97. doi: 10.1096/fj.14-260570. Epub 2014 Dec 4.

49.

Adaptive thermogenesis in white adipose tissue: is lactate the new brown(ing)?

Vergnes L, Reue K.

Diabetes. 2014 Oct;63(10):3175-6. doi: 10.2337/db14-0815. No abstract available.

50.

Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein.

Subramaniam SR, Vergnes L, Franich NR, Reue K, Chesselet MF.

Neurobiol Dis. 2014 Oct;70:204-13. doi: 10.1016/j.nbd.2014.06.017. Epub 2014 Jul 10.

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