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Items: 25


A Mucin 16 bispecific T cell-engaging antibody for the treatment of ovarian cancer.

Crawford A, Haber L, Kelly MP, Vazzana K, Canova L, Ram P, Pawashe A, Finney J, Jalal S, Chiu D, Colleton CA, Garnova E, Makonnen S, Hickey C, Krueger P, DelFino F, Potocky T, Kuhnert J, Godin S, Retter MW, Duramad P, MacDonald D, Olson WC, Fairhurst J, Huang T, Martin J, Lin JC, Smith E, Thurston G, Kirshner JR.

Sci Transl Med. 2019 Jun 19;11(497). pii: eaau7534. doi: 10.1126/scitranslmed.aau7534.


Anti-PCSK9 antibody pharmacokinetics and low-density lipoprotein-cholesterol pharmacodynamics in nonhuman primates are antigen affinity-dependent and exhibit limited sensitivity to neonatal Fc receptor-binding enhancement.

Henne KR, Ason B, Howard M, Wang W, Sun J, Higbee J, Tang J, Matsuda KC, Xu R, Zhou L, Chan JC, King C, Piper DE, Ketchem RR, Michaels ML, Jackson SM, Retter MW.

J Pharmacol Exp Ther. 2015 Apr;353(1):119-31. doi: 10.1124/jpet.114.221242. Epub 2015 Feb 4.


Impact of glycation on antibody clearance.

Yang J, Primack R, Frohn M, Wang W, Luan P, Retter MW, Flynn GC.

AAPS J. 2015 Jan;17(1):237-44. doi: 10.1208/s12248-014-9694-4. Epub 2014 Nov 21.


Evaluation of matrix microsampling methods for therapeutic drug candidate quantification in discovery-stage rodent pharmacokinetic studies.

Soto M, Pham R, Almon V, Wagner M, Primack R, Ponce M, Meyer J, James CA, Salyers KL, Retter MW.

Bioanalysis. 2014 Aug;6(16):2135-46. doi: 10.4155/bio.14.184.


Investigation of maternal and fetal exposure to an IgG2 monoclonal antibody following biweekly intravaginal administration to cynomolgus monkeys throughout pregnancy.

Moffat GJ, Davies R, Kwon G, Retter MW, Chellman GJ, Kanapuram S, Moore M, Loomis M, Wang W, Pyrah IT.

Reprod Toxicol. 2014 Sep;48:132-7. doi: 10.1016/j.reprotox.2014.05.003. Epub 2014 May 22.


Placental transfer of a fully human IgG2 monoclonal antibody in the cynomolgus monkey, rat, and rabbit: a comparative assessment from during organogenesis to late gestation.

Moffat GJ, Retter MW, Kwon G, Loomis M, Hock MB, Hall C, Bussiere J, Lewis EM, Chellman GJ.

Birth Defects Res B Dev Reprod Toxicol. 2014 Apr;101(2):178-88. doi: 10.1002/bdrb.21105.


Measurement of in vivo therapeutic mAb concentrations: comparison of conventional serum/plasma collection and analysis to dried blood spot sampling.

Matsuda KC, Hall C, Baker-Lee C, Soto M, Scott G, Prince PJ, Retter MW.

Bioanalysis. 2013 Aug;5(16):1979-90. doi: 10.4155/bio.13.148.


Effects of AMG 145 on low-density lipoprotein cholesterol levels: results from 2 randomized, double-blind, placebo-controlled, ascending-dose phase 1 studies in healthy volunteers and hypercholesterolemic subjects on statins.

Dias CS, Shaywitz AJ, Wasserman SM, Smith BP, Gao B, Stolman DS, Crispino CP, Smirnakis KV, Emery MG, Colbert A, Gibbs JP, Retter MW, Cooke BP, Uy ST, Matson M, Stein EA.

J Am Coll Cardiol. 2012 Nov 6;60(19):1888-98. doi: 10.1016/j.jacc.2012.08.986. Epub 2012 Oct 17.


Assessment of DBS technology for the detection of therapeutic antibodies.

Prince PJ, Matsuda KC, Retter M, Scott G.

Bioanalysis. 2010 Aug;2(8):1449-60. doi: 10.4155/bio.10.97.


A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.

Chan JC, Piper DE, Cao Q, Liu D, King C, Wang W, Tang J, Liu Q, Higbee J, Xia Z, Di Y, Shetterly S, Arimura Z, Salomonis H, Romanow WG, Thibault ST, Zhang R, Cao P, Yang XP, Yu T, Lu M, Retter MW, Kwon G, Henne K, Pan O, Tsai MM, Fuchslocher B, Yang E, Zhou L, Lee KJ, Daris M, Sheng J, Wang Y, Shen WD, Yeh WC, Emery M, Walker NP, Shan B, Schwarz M, Jackson SM.

Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9820-5. doi: 10.1073/pnas.0903849106. Epub 2009 May 14.


Characterization of a proapoptotic antiganglioside GM2 monoclonal antibody and evaluation of its therapeutic effect on melanoma and small cell lung carcinoma xenografts.

Retter MW, Johnson JC, Peckham DW, Bannink JE, Bangur CS, Dresser K, Cai F, Foy TM, Fanger NA, Fanger GR, Woda B, Rock KL.

Cancer Res. 2005 Jul 15;65(14):6425-34.


Identification and characterization of L985P, a CD20 related family member over-expressed in small cell lung carcinoma.

Bangur CS, Johnson JC, Switzer A, Wang YH, Hill B, Fanger GR, Wang T, Retter MW.

Int J Oncol. 2004 Dec;25(6):1583-90.


A novel method for increasing the expression level of recombinant proteins.

Wang A, Clapper J, Guderian JA, Foy TM, Fanger GR, Retter MW, Skeiky YA.

Protein Expr Purif. 2003 Jul;30(1):124-33.


Serum antibodies to lipophilin B detected in late stage breast cancer patients.

Carter D, Dillon DC, Reynolds LD, Retter MW, Fanger G, Molesh DA, Sleath PR, McNeill PD, Vedvick TS, Reed SG, Persing DH, Houghton RL.

Clin Cancer Res. 2003 Feb;9(2):749-54.


Detection of mammaglobin in the sera of patients with breast cancer.

Fanger GR, Houghton RL, Retter MW, Hendrickson RC, Babcook J, Dillon DC, Durham MD, Reynolds LD, Johnson JC, Carter D, Fleming TP, Roche PC, Persing DH, Reed SG.

Tumour Biol. 2002 Jul-Aug;23(4):212-21.


Characterization of KLK4 expression and detection of KLK4-specific antibody in prostate cancer patient sera.

Day CH, Fanger GR, Retter MW, Hylander BL, Penetrante RB, Houghton RL, Zhang X, McNeill PD, Filho AM, Nolasco M, Badaro R, Cheever MA, Reed SG, Dillon DC, Watanabe Y.

Oncogene. 2002 Oct 10;21(46):7114-20.


The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24.

Caudell EG, Mumm JB, Poindexter N, Ekmekcioglu S, Mhashilkar AM, Yang XH, Retter MW, Hill P, Chada S, Grimm EA.

J Immunol. 2002 Jun 15;168(12):6041-6.


Purification and characterization of the mammaglobin/lipophilin B complex, a promising diagnostic marker for breast cancer.

Carter D, Douglass JF, Cornellison CD, Retter MW, Johnson JC, Bennington AA, Fleming TP, Reed SG, Houghton RL, Diamond DL, Vedvick TS.

Biochemistry. 2002 May 28;41(21):6714-22.


Receptor editing: genetic reprogramming of autoreactive lymphocytes.

Retter MW, Nemazee D.

Cell Biochem Biophys. 1999;31(1):81-8. Review.


Receptor editing occurs frequently during normal B cell development.

Retter MW, Nemazee D.

J Exp Med. 1998 Oct 5;188(7):1231-8.


Autoreactive B cell regulation: peripheral induction of developmental arrest by lupus-associated autoantigens.

Santulli-Marotto S, Retter MW, Gee R, Mamula MJ, Clarke SH.

Immunity. 1998 Feb;8(2):209-19.


Both Sm and DNA are selecting antigens in the anti-Sm B cell response in autoimmune MRL/lpr mice.

Retter MW, Cohen PL, Eisenberg RA, Clarke SH.

J Immunol. 1996 Feb 1;156(3):1296-306.


Sm and DNA binding by dual reactive B cells requires distinct VH, V kappa, and VH CDR3 structures.

Retter MW, Eisenberg RA, Cohen PL, Clarke SH.

J Immunol. 1995 Aug 15;155(4):2248-57.


V region gene analysis of anti-Sm hybridomas from MRL/Mp-lpr/lpr mice.

Bloom DD, Davignon JL, Retter MW, Shlomchik MJ, Pisetsky DS, Cohen PL, Eisenberg RA, Clarke SH.

J Immunol. 1993 Feb 15;150(4):1591-610.


Sequence of a transcribed Physarum genomic DNA fragment containing a cluster of different U-RNA sequences.

Curran ME, Sullivan DS, Arn EA, Skinner HB, Retter MW, Adams DS.

Nucleic Acids Res. 1988 Oct 25;16(20):9867. No abstract available.

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