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Items: 13

1.

Expression of Contactin 4 Is Associated With Malignant Behavior in Pheochromocytomas and Paragangliomas.

Evenepoel L, van Nederveen FH, Oudijk L, Papathomas TG, Restuccia DF, Belt EJT, de Herder WW, Feelders RA, Franssen GJH, Hamoir M, Maiter D, Ghayee HK, Shay JW, Perren A, Timmers HJLM, van Eeden S, Vroonen L, Aydin S, Robledo M, Vikkula M, de Krijger RR, Dinjens WNM, Persu A, Korpershoek E.

J Clin Endocrinol Metab. 2018 Jan 1;103(1):46-55. doi: 10.1210/jc.2017-01314.

PMID:
28938490
2.

Sarcomatoid adrenocortical carcinoma: a comprehensive pathological, immunohistochemical, and targeted next-generation sequencing analysis.

Papathomas TG, Duregon E, Korpershoek E, Restuccia DF, van Marion R, Cappellesso R, Sturm N, Rossi G, Coli A, Zucchini N, Stoop H, Oosterhuis W, Ventura L, Volante M, Fassina A, Dinjens WN, Papotti M, de Krijger RR.

Hum Pathol. 2016 Dec;58:113-122. doi: 10.1016/j.humpath.2016.08.006. Epub 2016 Aug 31.

3.

Complex MAX Rearrangement in a Family With Malignant Pheochromocytoma, Renal Oncocytoma, and Erythrocytosis.

Korpershoek E, Koffy D, Eussen BH, Oudijk L, Papathomas TG, van Nederveen FH, Belt EJ, Franssen GJ, Restuccia DF, Krol NM, van der Luijt RB, Feelders RA, Oldenburg RA, van Ijcken WF, de Klein A, de Herder WW, de Krijger RR, Dinjens WN.

J Clin Endocrinol Metab. 2016 Feb;101(2):453-60. doi: 10.1210/jc.2015-2592. Epub 2015 Dec 15.

PMID:
26670126
4.

Immunohistochemical expression of stem cell markers in pheochromocytomas/paragangliomas is associated with SDHx mutations.

Oudijk L, Neuhofer CM, Lichtenauer UD, Papathomas TG, Korpershoek E, Stoop H, Oosterhuis JW, Smid M, Restuccia DF, Robledo M, de Cubas AA, Mannelli M, Gimenez-Roqueplo AP, Dinjens WN, Beuschlein F, de Krijger RR.

Eur J Endocrinol. 2015 Jul;173(1):43-52. doi: 10.1530/EJE-14-1164. Epub 2015 Apr 27.

PMID:
25916394
5.

The PI3K-PKB/Akt pathway.

Hemmings BA, Restuccia DF.

Cold Spring Harb Perspect Biol. 2015 Apr 1;7(4). pii: a026609. doi: 10.1101/cshperspect.a026609. No abstract available.

6.

Telomerase reverse transcriptase promoter mutations in tumors originating from the adrenal gland and extra-adrenal paraganglia.

Papathomas TG, Oudijk L, Zwarthoff EC, Post E, Duijkers FA, van Noesel MM, Hofland LJ, Pollard PJ, Maher ER, Restuccia DF, Feelders RA, Franssen GJ, Timmers HJ, Sleijfer S, de Herder WW, de Krijger RR, Dinjens WN, Korpershoek E.

Endocr Relat Cancer. 2014 Aug;21(4):653-61. doi: 10.1530/ERC-13-0429. Epub 2014 Jun 20.

PMID:
24951106
7.

Non-pheochromocytoma (PCC)/paraganglioma (PGL) tumors in patients with succinate dehydrogenase-related PCC-PGL syndromes: a clinicopathological and molecular analysis.

Papathomas TG, Gaal J, Corssmit EP, Oudijk L, Korpershoek E, Heimdal K, Bayley JP, Morreau H, van Dooren M, Papaspyrou K, Schreiner T, Hansen T, Andresen PA, Restuccia DF, van Kessel I, van Leenders GJ, Kros JM, Looijenga LH, Hofland LJ, Mann W, van Nederveen FH, Mete O, Asa SL, de Krijger RR, Dinjens WN.

Eur J Endocrinol. 2013 Nov 22;170(1):1-12. doi: 10.1530/EJE-13-0623. Print 2014 Jan.

PMID:
24096523
8.

PI3K-PKB/Akt pathway.

Hemmings BA, Restuccia DF.

Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a011189. doi: 10.1101/cshperspect.a011189. Review. No abstract available. Erratum in: Cold Spring Harb Perspect Biol. 2015 Apr;7(4). pii: a026609. doi: 10.1101/cshperspect.a026609.

9.

Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-β signaling axes.

Xue G, Restuccia DF, Lan Q, Hynx D, Dirnhofer S, Hess D, Rüegg C, Hemmings BA.

Cancer Discov. 2012 Mar;2(3):248-59. doi: 10.1158/2159-8290.CD-11-0270. Epub 2012 Jan 25.

10.

Loss of PKBβ/Akt2 predisposes mice to ovarian cyst formation and increases the severity of polycystic ovary formation in vivo.

Restuccia DF, Hynx D, Hemmings BA.

Dis Model Mech. 2012 May;5(3):403-11. doi: 10.1242/dmm.008136. Epub 2012 Jan 24.

11.

From man to mouse and back again: advances in defining tumor AKTivities in vivo.

Restuccia DF, Hemmings BA.

Dis Model Mech. 2010 Nov-Dec;3(11-12):705-20. doi: 10.1242/dmm.004671. Epub 2010 Oct 12. Review.

12.

PKB/AKT phosphorylation of the transcription factor Twist-1 at Ser42 inhibits p53 activity in response to DNA damage.

Vichalkovski A, Gresko E, Hess D, Restuccia DF, Hemmings BA.

Oncogene. 2010 Jun 17;29(24):3554-65. doi: 10.1038/onc.2010.115. Epub 2010 Apr 19.

PMID:
20400976
13.

Cell signaling. Blocking Akt-ivity.

Restuccia DF, Hemmings BA.

Science. 2009 Aug 28;325(5944):1083-4. doi: 10.1126/science.1179972. No abstract available.

PMID:
19713516

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