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Omega-3 fatty acids in contrast to omega-6 protect against pneumococcal pneumonia.

Hinojosa CA, Gonzalez-Juarbe N, Rahman MM, Fernandes G, Orihuela CJ, Restrepo MI.

Microb Pathog. 2020 Jan 16:103979. doi: 10.1016/j.micpath.2020.103979. [Epub ahead of print]


Evidence supporting recommendations from international guidelines on treatment, diagnosis, and prevention of HAP and VAP in adults.

Campogiani L, Tejada S, Ferreira-Coimbra J, Restrepo MI, Rello J.

Eur J Clin Microbiol Infect Dis. 2019 Dec 10. doi: 10.1007/s10096-019-03748-z. [Epub ahead of print]


Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America.

Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K, Cooley LA, Dean NC, Fine MJ, Flanders SA, Griffin MR, Metersky ML, Musher DM, Restrepo MI, Whitney CG.

Am J Respir Crit Care Med. 2019 Oct 1;200(7):e45-e67. doi: 10.1164/rccm.201908-1581ST.


New perspectives in aspiration community acquired Pneumonia.

Rodriguez AE, Restrepo MI.

Expert Rev Clin Pharmacol. 2019 Oct;12(10):991-1002. doi: 10.1080/17512433.2019.1663730. Epub 2019 Oct 14. Review.


A National Needs Assessment of Point-of-Care Ultrasound Training for Hospitalists.

LoPresti CM, Boyd JS, Schott C, Core M, Lucas BP, Colon-Molero A, Kessler C, Mader MJ, Haro EK, Finley EP, Restrepo MI, Pugh J, Soni NJ.

Mayo Clin Proc. 2019 Sep;94(9):1910-1912. doi: 10.1016/j.mayocp.2019.07.016. No abstract available. Erratum in: Mayo Clin Proc. 2019 Dec;94(12):2597.


Animal Models of Pneumococcal pneumonia.

Borsa N, Pasquale MD, Restrepo MI.

Int J Mol Sci. 2019 Aug 28;20(17). pii: E4220. doi: 10.3390/ijms20174220. Review.


Web-Based Visualization of MeSH-Based PubMed/MEDLINE Statistics.

Restrepo MI, McGrath MC, Sarkar IN, Chen ES.

Stud Health Technol Inform. 2019 Aug 21;264:1490-1491. doi: 10.3233/SHTI190499.


Decoding task engagement from distributed network electrophysiology in humans.

Provenza NR, Paulk AC, Peled N, Restrepo MI, Cash SS, Dougherty DD, Eskandar EN, Borton DA, Widge AS.

J Neural Eng. 2019 Aug 16;16(5):056015. doi: 10.1088/1741-2552/ab2c58.


Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia.

Villafuerte D, Aliberti S, Soni NJ, Faverio P, Marcos PJ, Wunderink RG, Rodriguez A, Sibila O, Sanz F, Martin-Loeches I, Menzella F, Reyes LF, Jankovic M, Spielmanns M, Restrepo MI; GLIMP Investigators.

Respirology. 2019 Aug 5. doi: 10.1111/resp.13663. [Epub ahead of print]


International prevalence and risk factors evaluation for drug-resistant Streptococcus pneumoniae pneumonia.

Aliberti S, Cook GS, Babu BL, Reyes LF, H Rodriguez A, Sanz F, Soni NJ, Anzueto A, Faverio P, Sadud RF, Muhammad I, Prat C, Vendrell E, Neves J, Kaimakamis E, Feneley A, Swarnakar R, Franzetti F, Carugati M, Morosi M, Monge E, Restrepo MI; GLIMP investigators.

J Infect. 2019 Oct;79(4):300-311. doi: 10.1016/j.jinf.2019.07.004. Epub 2019 Jul 9.


Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients.

Di Pasquale MF, Sotgiu G, Gramegna A, Radovanovic D, Terraneo S, Reyes LF, Rupp J, González Del Castillo J, Blasi F, Aliberti S, Restrepo MI; GLIMP Investigators .

Clin Infect Dis. 2019 Apr 24;68(9):1482-1493. doi: 10.1093/cid/ciy723.


Solr-Plant: efficient extraction of plant names from text.

Sharma V, Restrepo MI, Sarkar IN.

BMC Bioinformatics. 2019 May 22;20(1):263. doi: 10.1186/s12859-019-2874-6.


Current use and training needs of point-of-care ultrasound in emergency departments: A national survey of VA hospitals.

Boyd JS, LoPresti CM, Core M, Schott C, Mader MJ, Lucas BP, Haro EK, Finley EP, Restrepo MI, Kessler C, Colon-Molero A, Pugh J, Soni NJ.

Am J Emerg Med. 2019 Sep;37(9):1794-1797. doi: 10.1016/j.ajem.2019.02.043. Epub 2019 Feb 28. No abstract available.


Biomarkers in community-acquired pneumonia: still searching for the one.

Sibila O, Restrepo MI.

Eur Respir J. 2019 Feb 28;53(2). pii: 1802469. doi: 10.1183/13993003.02469-2018. Print 2019 Feb. No abstract available.


Atypical pathogens in hospitalized patients with community-acquired pneumonia: a worldwide perspective.

Gramegna A, Sotgiu G, Di Pasquale M, Radovanovic D, Terraneo S, Reyes LF, Vendrell E, Neves J, Menzella F, Blasi F, Aliberti S, Restrepo MI; GLIMP Study Group.

BMC Infect Dis. 2018 Dec 18;18(1):677. doi: 10.1186/s12879-018-3565-z.


Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study.

Carugati M, Aliberti S, Reyes LF, Franco Sadud R, Irfan M, Prat C, Soni NJ, Faverio P, Gori A, Blasi F, Restrepo MI.

ERJ Open Res. 2018 Oct 8;4(4). pii: 00096-2018. doi: 10.1183/23120541.00096-2018. eCollection 2018 Oct.


Pneumonia is a neglected problem: it is now time to act.

Aliberti S, Dela Cruz CS, Sotgiu G, Restrepo MI.

Lancet Respir Med. 2019 Jan;7(1):10-11. doi: 10.1016/S2213-2600(18)30470-3. Epub 2018 Nov 12. No abstract available.


An international perspective on hospitalized patients with viral community-acquired pneumonia.

Radovanovic D, Sotgiu G, Jankovic M, Mahesh PA, Marcos PJ, Abdalla MI, Di Pasquale MF, Gramegna A, Terraneo S, Blasi F, Santus P, Aliberti S, Reyes LF, Restrepo MI; GLIMP Study Group.

Eur J Intern Med. 2019 Feb;60:54-70. doi: 10.1016/j.ejim.2018.10.020. Epub 2018 Nov 4.


Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study.

Moreno G, Rodríguez A, Reyes LF, Gomez J, Sole-Violan J, Díaz E, Bodí M, Trefler S, Guardiola J, Yébenes JC, Soriano A, Garnacho-Montero J, Socias L, Del Valle Ortíz M, Correig E, Marín-Corral J, Vallverdú-Vidal M, Restrepo MI, Torres A, Martín-Loeches I; GETGAG Study Group.

Intensive Care Med. 2018 Sep;44(9):1470-1482. doi: 10.1007/s00134-018-5332-4. Epub 2018 Aug 3.


Pseudomonas aeruginosa in Chronic Obstructive Pulmonary Disease Patients with Frequent Hospitalized Exacerbations: A Prospective Multicentre Study.

Rodrigo-Troyano A, Melo V, Marcos PJ, Laserna E, Peiro M, Suarez-Cuartin G, Perea L, Feliu A, Plaza V, Faverio P, Restrepo MI, Anzueto A, Sibila O.

Respiration. 2018;96(5):417-424. doi: 10.1159/000490190. Epub 2018 Jul 24.


Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a multinational point prevalence study of hospitalised patients.

Restrepo MI, Babu BL, Reyes LF, Chalmers JD, Soni NJ, Sibila O, Faverio P, Cilloniz C, Rodriguez-Cintron W, Aliberti S; GLIMP.

Eur Respir J. 2018 Aug 9;52(2). pii: 1701190. doi: 10.1183/13993003.01190-2017. Print 2018 Aug.


Pneumonia in Patients with Chronic Obstructive Pulmonary Disease.

Restrepo MI, Sibila O, Anzueto A.

Tuberc Respir Dis (Seoul). 2018 Jul;81(3):187-197. doi: 10.4046/trd.2018.0030. Review.


Effect of pulsed xenon ultraviolet room disinfection devices on microbial counts for methicillin-resistant Staphylococcus aureus and aerobic bacterial colonies.

Zeber JE, Pfeiffer C, Baddley JW, Cadena-Zuluaga J, Stock EM, Copeland LA, Hendricks J, Mohammadi J, Restrepo MI, Jinadatha C.

Am J Infect Control. 2018 Jun;46(6):668-673. doi: 10.1016/j.ajic.2018.02.001. Epub 2018 Apr 11.


Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During Pneumonia.

Gonzalez-Juarbe N, Bradley KM, Riegler AN, Reyes LF, Brissac T, Park SS, Restrepo MI, Orihuela CJ.

Sci Rep. 2018 Apr 11;8(1):5846. doi: 10.1038/s41598-018-24210-8.


Relationship between acute kidney injury and serum procalcitonin (PCT) concentration in critically ill patients with influenza infection.

Rodríguez A, Reyes LF, Monclou J, Suberviola B, Bodí M, Sirgo G, Solé-Violán J, Guardiola J, Barahona D, Díaz E, Martín-Loeches I, Restrepo MI; on behalf GETGAG study group.

Med Intensiva. 2018 Oct;42(7):399-408. doi: 10.1016/j.medin.2017.12.004. Epub 2018 Feb 9. English, Spanish.


Pneumonia as a cardiovascular disease.

Restrepo MI, Reyes LF.

Respirology. 2018 Mar;23(3):250-259. doi: 10.1111/resp.13233. Epub 2018 Jan 11. Review.


Bronchiectasis Management: The State of the Union.

Chalmers JD, Restrepo MI.

Chest. 2017 Dec;152(6):1097-1099. doi: 10.1016/j.chest.2017.07.037. No abstract available.


In vitro evaluation of aerosol delivery of aztreonam lysine (AZLI): an adult mechanical ventilation model.

Rodríguez A, Cabrera M, Reyes LF, Bodí M, Trefler S, Canadell L, Barahona D, Ehrmann S, Martin-Loeches I, Restrepo MI, Vecellio L.

Expert Opin Drug Deliv. 2017 Dec;14(12):1447-1453. doi: 10.1080/17425247.2017.1393411. Epub 2017 Oct 23.


Effects of intrapulmonary percussive ventilation on airway mucus clearance: A bench model.

Fernandez-Restrepo L, Shaffer L, Amalakuhan B, Restrepo MI, Peters J, Restrepo R.

World J Crit Care Med. 2017 Aug 4;6(3):164-171. doi: 10.5492/wjccm.v6.i3.164. eCollection 2017 Aug 4.


Discordance of physician clinical judgment vs. pneumonia severity index (PSI) score to admit patients with low risk community-acquired pneumonia: a prospective multicenter study.

Marcos PJ, Restrepo MI, González-Barcala FJ, Soni NJ, Vidal I, Sanjuàn P, Llinares D, Ferreira-Gonzalez L, Rábade C, Otero-González I, Marcos P, Verea-Hernando H.

J Thorac Dis. 2017 Jun;9(6):1538-1546. doi: 10.21037/jtd.2017.05.44.


Risk Factors for Noninvasive Ventilation Failure in Critically Ill Subjects With Confirmed Influenza Infection.

Rodríguez A, Ferri C, Martin-Loeches I, Díaz E, Masclans JR, Gordo F, Sole-Violán J, Bodí M, Avilés-Jurado FX, Trefler S, Magret M, Moreno G, Reyes LF, Marin-Corral J, Yebenes JC, Esteban A, Anzueto A, Aliberti S, Restrepo MI; Grupo Español de Trabajo Gripe A Grave (GETGAG)/Sociedad Española de Medicina Intensiva, Crítica y Unidades Coronarias (SEMICYUC) Working Group; 2009-2015 H1N1 SEMICYUC Working Group investigators.

Respir Care. 2017 Oct;62(10):1307-1315. doi: 10.4187/respcare.05481. Epub 2017 Jul 11.


High endocan levels are associated with the need for mechanical ventilation among patients with severe sepsis.

Mangat M, Amalakuhan B, Habib S, Reyes LF, Hinojosa CA, Rodriguez AH, Soni NJ, Anzueto A, Levine SM, Peters JI, Aliberti S, Sibila O, Rello J, Witzenrath M, Waterer GW, Martin-Loeches I, Blanquer J, Sanz F, Marcos PJ, Solé-Violán J, Chalmers JD, Feldman C, Wunderink RG, Cruz CSD, Orihuela CJ, Restrepo MI.

Eur Respir J. 2017 Jul 5;50(1). pii: 1700013. doi: 10.1183/13993003.00013-2017. Print 2017 Jul. No abstract available.


Age-related differences in management and outcomes in hospitalized healthy and well-functioning bacteremic pneumococcal pneumonia patients: a cohort study.

Ruiz LA, España PP, Gómez A, Bilbao A, Jaca C, Arámburu A, Capelastegui A, Restrepo MI, Zalacain R.

BMC Geriatr. 2017 Jun 20;17(1):130. doi: 10.1186/s12877-017-0518-0.


Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling.

Reyes LF, Restrepo MI, Hinojosa CA, Soni NJ, Anzueto A, Babu BL, Gonzalez-Juarbe N, Rodriguez AH, Jimenez A, Chalmers JD, Aliberti S, Sibila O, Winter VT, Coalson JJ, Giavedoni LD, Dela Cruz CS, Waterer GW, Witzenrath M, Suttorp N, Dube PH, Orihuela CJ.

Am J Respir Crit Care Med. 2017 Sep 1;196(5):609-620. doi: 10.1164/rccm.201701-0104OC.


Managing community acquired pneumonia in the elderly - the next generation of pharmacotherapy on the horizon.

Amalakuhan B, Echevarria KL, Restrepo MI.

Expert Opin Pharmacother. 2017 Aug;18(11):1039-1048. doi: 10.1080/14656566.2017.1340937. Epub 2017 Jun 21. Review.


Prophylactic Acid-Suppressive Therapy in Hospitalized Adults: Indications, Benefits, and Infectious Complications.

Faust AC, Echevarria KL, Attridge RL, Sheperd L, Restrepo MI.

Crit Care Nurse. 2017 Jun;37(3):18-29. doi: 10.4037/ccn2017720.


Inhaled Antibiotic Therapy in Chronic Respiratory Diseases.

Maselli DJ, Keyt H, Restrepo MI.

Int J Mol Sci. 2017 May 16;18(5). pii: E1062. doi: 10.3390/ijms18051062. Review.


Using cluster analysis of cytokines to identify patterns of inflammation in hospitalized patients with community-acquired pneumonia: a pilot study.

Wiemken TL, Kelley RR, Fernandez-Botran R, Mattingly WA, Arnold FW, Furmanek SP, Restrepo MI, Chalmers JD, Peyrani P, Cavallazzi R, Bordon J, Aliberti S, Ramirez JA.

Univ Louisville J Respir Infect. 2017;1(1):3-11. doi: 10.18297/jri/vol1/iss1/1/. Epub 2017 Jan 30.


Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia.

González-Juarbe N, Bradley KM, Shenoy AT, Gilley RP, Reyes LF, Hinojosa CA, Restrepo MI, Dube PH, Bergman MA, Orihuela CJ.

Cell Death Differ. 2017 May;24(5):917-928. doi: 10.1038/cdd.2017.49. Epub 2017 Apr 7.


Maladaptive Suppression of Bacterial Clearance in Early Sepsis. Setting the Scene for Failure.

Waterer G, Restrepo MI.

Am J Respir Crit Care Med. 2017 Apr 1;195(7):846-847. doi: 10.1164/rccm.201610-1975ED. No abstract available.


Relationship Between Severity Classification of Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Clinical Outcomes in Hospitalized Patients.

Marcos PJ, Sanjuán P, Huerta A, Nieto-Codesido I, Ferreira-Gonzalez L, Sibila O, Restrepo MI.

Cureus. 2017 Jan 22;9(1):e988. doi: 10.7759/cureus.988.


Year in review 2016: Respiratory infections, acute respiratory distress syndrome, pleural diseases, lung cancer and interventional pulmonology.

Restrepo MI, Chalmers JD, Song Y, Mallow C, Hewlett J, Maldonado F, Yarmus L.

Respirology. 2017 Apr;22(3):602-611. doi: 10.1111/resp.13016. Epub 2017 Feb 28. Review. No abstract available.


Complication of Community-Acquired Pneumonia (Including Cardiac Complications).

Restrepo MI, Reyes LF, Anzueto A.

Semin Respir Crit Care Med. 2016 Dec;37(6):897-904. Epub 2016 Dec 13. Review.


Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study.

McDonnell MJ, Aliberti S, Goeminne PC, Restrepo MI, Finch S, Pesci A, Dupont LJ, Fardon TC, Wilson R, Loebinger MR, Skrbic D, Obradovic D, De Soyza A, Ward C, Laffey JG, Rutherford RM, Chalmers JD.

Lancet Respir Med. 2016 Dec;4(12):969-979. doi: 10.1016/S2213-2600(16)30320-4. Epub 2016 Nov 16.


A Non-Human Primate Model of Severe Pneumococcal Pneumonia.

Reyes LF, Restrepo MI, Hinojosa CA, Soni NJ, Shenoy AT, Gilley RP, Gonzalez-Juarbe N, Noda JR, Winter VT, de la Garza MA, Shade RE, Coalson JJ, Giavedoni LD, Anzueto A, Orihuela CJ.

PLoS One. 2016 Nov 17;11(11):e0166092. doi: 10.1371/journal.pone.0166092. eCollection 2016.


Reply: Measuring Airway Mucin 2 in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization.

Sibila O, Mateus EF, Restrepo MI, Chalmers JD, Vidal S.

Ann Am Thorac Soc. 2016 Nov;13(11):2104-2105. No abstract available.


Health care-associated pneumonia in the intensive care unit: Guideline-concordant antibiotics and outcomes.

Attridge RT, Frei CR, Pugh MJ, Lawson KA, Ryan L, Anzueto A, Metersky ML, Restrepo MI, Mortensen EM.

J Crit Care. 2016 Dec;36:265-271. doi: 10.1016/j.jcrc.2016.08.004. Epub 2016 Aug 11.


Use of ultrasound guidance for central venous catheterization: a national survey of intensivists and hospitalists.

Soni NJ, Reyes LF, Keyt H, Arango A, Gelfond JA, Peters JI, Levine SM, Adams SG, Restrepo MI.

J Crit Care. 2016 Dec;36:277-283. doi: 10.1016/j.jcrc.2016.07.014. Epub 2016 Jul 17.


Admission inferior vena cava measurements are associated with mortality after hospitalization for acute decompensated heart failure.

Cubo-Romano P, Torres-Macho J, Soni NJ, Reyes LF, Rodríguez-Almodóvar A, Fernández-Alonso JM, González-Davia R, Casas-Rojo JM, Restrepo MI, de Casasola GG.

J Hosp Med. 2016 Nov;11(11):778-784. doi: 10.1002/jhm.2620. Epub 2016 Jun 6.


Global initiative for meticillin-resistant Staphylococcus aureus pneumonia (GLIMP): an international, observational cohort study.

Aliberti S, Reyes LF, Faverio P, Sotgiu G, Dore S, Rodriguez AH, Soni NJ, Restrepo MI; GLIMP investigators.

Lancet Infect Dis. 2016 Dec;16(12):1364-1376. doi: 10.1016/S1473-3099(16)30267-5. Epub 2016 Sep 1. Erratum in: Lancet Infect Dis. 2016 Dec;16(12):1324.


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