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Strains matter: Success of murine in vitro spermatogenesis is dependent on genetic background.

Portela JMD, Mulder CL, van Daalen SKM, de Winter-Korver CM, Stukenborg JB, Repping S, van Pelt AMM.

Dev Biol. 2019 Aug 14. pii: S0012-1606(19)30370-7. doi: 10.1016/j.ydbio.2019.08.007. [Epub ahead of print]


Primary human testicular PDGFRα+ cells are multipotent and can be differentiated into cells with Leydig cell characteristics in vitro.

Eliveld J, van den Berg EA, Chikhovskaya JV, van Daalen SKM, de Winter-Korver CM, van der Veen F, Repping S, Teerds K, van Pelt AMM.

Hum Reprod. 2019 Sep 29;34(9):1621-1631. doi: 10.1093/humrep/dez131.


Premature expression of the decidualization marker prolactin is associated with repeated implantation failure.

Berkhout RP, Lambalk CB, Repping S, Hamer G, Mastenbroek S.

Gynecol Endocrinol. 2019 Aug 7:1-5. doi: 10.1080/09513590.2019.1650344. [Epub ahead of print]


The composition of human preimplantation embryo culture media and their stability during storage and culture.

Tarahomi M, Vaz FM, Straalen JPV, Schrauwen FAP, Wely MV, Hamer G, Repping S, Mastenbroek S.

Hum Reprod. 2019 Jul 26. pii: dez102. doi: 10.1093/humrep/dez102. [Epub ahead of print]


The AID study: protocol for a randomised controlled trial of intrauterine insemination in the natural cycle compared with intracervical insemination in the natural cycle.

Kop P, van Wely M, Nap A, Willem Mol B, Bernardus R, Brucker M, Janssens P, Cohlen B, Pieters J, Repping S, van der Veen F, Mochtar MH.

BMJ Open. 2019 Jul 23;9(7):e026065. doi: 10.1136/bmjopen-2018-026065.


The 'Pleasure&Pregnancy' web-based interactive educational programme versus expectant management in the treatment of unexplained subfertility: protocol for a randomised controlled trial.

Dancet EAF, D'Hooghe TM, Dreischor F, van Wely M, Laan ETM, Lambalk CB, Repping S, Custers IM.

BMJ Open. 2019 Jul 9;9(7):e025845. doi: 10.1136/bmjopen-2018-025845.


The relative importance of genetic parenthood.

Hendriks S, van Wely M, D'Hooghe TM, Meissner A, Mol F, Peeraer K, Repping S, Dancet EAF.

Reprod Biomed Online. 2019 Jul;39(1):103-110. doi: 10.1016/j.rbmo.2019.02.008. Epub 2019 Mar 12.


Follicle stimulating hormone or clomiphene citrate in intrauterine insemination with ovarian stimulation for unexplained subfertility: a role for treatment selection markers?

Danhof NA, van Eekelen R, Repping S, Mol BWJ, van der Veen F, van Wely M, Mochtar MH; SUPER Study group.

Reprod Biomed Online. 2019 Jun;38(6):938-942. doi: 10.1016/j.rbmo.2019.01.014. Epub 2019 Mar 2.


Reasons for being in favour of or against genome modification: a survey of the Dutch general public.

Hendriks S, Giesbertz NAA, Bredenoord AL, Repping S.

Hum Reprod Open. 2018 May 16;2018(3):hoy008. doi: 10.1093/hropen/hoy008. eCollection 2018.


A protocol developing, disseminating and implementing a core outcome set for infertility.

Duffy JMN, Bhattacharya S, Curtis C, Evers JLH, Farquharson RG, Franik S, Khalaf Y, Legro RS, Lensen S, Mol BW, Niederberger C, Ng EHY, Repping S, Strandell A, Torrance HL, Vail A, van Wely M, Vuong NL, Wang AY, Wang R, Wilkinson J, Youssef MA, Farquhar CM; COMMIT: Core Outcomes Measures for Infertility Trials.

Hum Reprod Open. 2018 Jun 15;2018(3):hoy007. doi: 10.1093/hropen/hoy007. eCollection 2018. Review.


Hormonal medication in medically assisted reproduction: a systematic review of assessments from patients.

Lankreijer K, D'Hooghe TM, Apers S, Sermeus W, Repping S, Dancet EA.

Reprod Biomed Online. 2019 Mar;38(3):341-363. doi: 10.1016/j.rbmo.2018.12.047. Epub 2019 Jan 19. Review.


Evidence-based medicine and infertility treatment.

Repping S.

Lancet. 2019 Feb 2;393(10170):380-382. doi: 10.1016/S0140-6736(19)30200-4. No abstract available.


Female subfertility.

Farquhar CM, Bhattacharya S, Repping S, Mastenbroek S, Kamath MS, Marjoribanks J, Boivin J.

Nat Rev Dis Primers. 2019 Jan 24;5(1):7. doi: 10.1038/s41572-018-0058-8. Review.


In Vitro Maturation of Oocytes in Women at Risk of Ovarian Hyperstimulation Syndrome-A Prospective Multicenter Cohort Study.

Braam SC, Consten D, Smeenk JMJ, Cohlen BJ, Curfs MHJM, Hamilton CJCM, Repping S, Mol BWJ, de Bruin JP.

Int J Fertil Steril. 2019 Apr;13(1):38-44. doi: 10.22074/ijfs.2019.5452. Epub 2019 Jan 6.


Simultaneous Purification of Round and Elongated Spermatids from Testis Tissue Using a FACS-Based DNA Ploidy Assay.

Struijk RB, De Winter-Korver CM, van Daalen SKM, Hooibrink B, Repping S, van Pelt AMM.

Cytometry A. 2019 Mar;95(3):309-313. doi: 10.1002/cyto.a.23698. Epub 2018 Dec 19.


Orchidopexy for bilateral undescended testes: A multicentre study on its effects on fertility and comparison of two fixation techniques.

Uijldert M, Meißner A, Kuijper CF, Repping S, de Jong TPVM, Chrzan RJ.

Andrologia. 2019 Apr;51(3):e13194. doi: 10.1111/and.13194. Epub 2018 Nov 8.


Reproductive outcomes after oocyte banking for fertility preservation.

Balkenende EM, Dahhan T, van der Veen F, Repping S, Goddijn M.

Reprod Biomed Online. 2018 Oct;37(4):425-433. doi: 10.1016/j.rbmo.2018.07.005.


Age-related gene expression profiles of immature human oocytes.

Smits MAJ, Wong KM, Mantikou E, Korver CM, Jongejan A, Breit TM, Goddijn M, Mastenbroek S, Repping S.

Mol Hum Reprod. 2018 Oct 1;24(10):469-477. doi: 10.1093/molehr/gay036.


pH stability of human preimplantation embryo culture media: effects of culture and batches.

Tarahomi M, de Melker AA, van Wely M, Hamer G, Repping S, Mastenbroek S.

Reprod Biomed Online. 2018 Oct;37(4):409-414. doi: 10.1016/j.rbmo.2018.08.011. Epub 2018 Aug 29.


The influence of retinoic acid-induced differentiation on the radiation response of male germline stem cells.

Zheng Y, Lei Q, Jongejan A, Mulder CL, van Daalen SKM, Mastenbroek S, Hwang G, Jordan PW, Repping S, Hamer G.

DNA Repair (Amst). 2018 Oct;70:55-66. doi: 10.1016/j.dnarep.2018.08.027. Epub 2018 Aug 28.


Follicle stimulating hormone versus clomiphene citrate in intrauterine insemination for unexplained subfertility: a randomized controlled trial.

Danhof NA, van Wely M, Repping S, Koks C, Verhoeve HR, de Bruin JP, Verberg MFG, van Hooff MHA, Cohlen BJ, van Heteren CF, Fleischer K, Gianotten J, van Disseldorp J, Visser J, Broekmans FJM, Mol BWJ, van der Veen F, Mochtar MH; SUPER study group.

Hum Reprod. 2018 Oct 1;33(10):1866-1874. doi: 10.1093/humrep/dey268.


The ethics of clinical applications of germline genome modification: a systematic review of reasons.

van Dijke I, Bosch L, Bredenoord AL, Cornel M, Repping S, Hendriks S.

Hum Reprod. 2018 Sep 1;33(9):1777-1796. doi: 10.1093/humrep/dey257.


Reproductive medicine: still more ART than science?

Wilkinson J, Bhattacharya S, Duffy J, Kamath MS, Marjoribanks J, Repping S, Vail A, van Wely M, Farquhar CM.

BJOG. 2019 Jan;126(2):138-141. doi: 10.1111/1471-0528.15409. Epub 2018 Aug 23. No abstract available.


Massive expression of germ cell-specific genes is a hallmark of cancer and a potential target for novel treatment development.

Bruggeman JW, Koster J, Lodder P, Repping S, Hamer G.

Oncogene. 2018 Oct;37(42):5694-5700. doi: 10.1038/s41388-018-0357-2. Epub 2018 Jun 15.


An informed decision between cleavage-stage and blastocyst-stage transfer in IVF requires data on the transfers of frozen-thawed embryos.

Cornelisse S, Fleischer K, Repping S, Mastenbroek S.

Hum Reprod. 2018 Jul 1;33(7):1370. doi: 10.1093/humrep/dey112. No abstract available.


The risk of TESE-induced hypogonadism: a systematic review and meta-analysis.

Eliveld J, van Wely M, Meißner A, Repping S, van der Veen F, van Pelt AMM.

Hum Reprod Update. 2018 Jul 1;24(4):442-454. doi: 10.1093/humupd/dmy015.


A practical blueprint to systematically study life-long health consequences of novel medically assisted reproductive treatments.

Mulder CL, Serrano JB, Catsburg LAE, Roseboom TJ, Repping S, van Pelt AMM.

Hum Reprod. 2018 May 1;33(5):784-792. doi: 10.1093/humrep/dey070.


Distinct prophase arrest mechanisms in human male meiosis.

Jan SZ, Jongejan A, Korver CM, van Daalen SKM, van Pelt AMM, Repping S, Hamer G.

Development. 2018 Apr 16;145(16). pii: dev160614. doi: 10.1242/dev.160614.


High-quality human preimplantation embryos actively influence endometrial stromal cell migration.

Berkhout RP, Lambalk CB, Huirne J, Mijatovic V, Repping S, Hamer G, Mastenbroek S.

J Assist Reprod Genet. 2018 Apr;35(4):659-667. doi: 10.1007/s10815-017-1107-z. Epub 2017 Dec 28.


Broad support for regulating the clinical implementation of future reproductive techniques.

Hendriks S, Vliegenthart R, Repping S, Dancet EAF.

Hum Reprod. 2018 Jan 1;33(1):39-46. doi: 10.1093/humrep/dex355.


Long-term health in recipients of transplanted in vitro propagated spermatogonial stem cells.

Mulder CL, Catsburg LAE, Zheng Y, de Winter-Korver CM, van Daalen SKM, van Wely M, Pals S, Repping S, van Pelt AMM.

Hum Reprod. 2018 Jan 1;33(1):81-90. doi: 10.1093/humrep/dex348.


The addition of a low-quality embryo as part of a fresh day 3 double embryo transfer does not improve ongoing pregnancy rates.

Berkhout RP, Vergouw CG, van Wely M, de Melker AA, Schats R, Repping S, Hamer G, Mastenbroek S, Lambalk CB.

Hum Reprod Open. 2017 Nov 23;2017(3):hox020. doi: 10.1093/hropen/hox020. eCollection 2017.


Constructing the crystal ball: how to get reliable prognostic information for the management of subfertile couples.

van Eekelen R, van Geloven N, van Wely M, McLernon DJ, Eijkemans MJ, Repping S, Steyerberg EW, Mol BW, Bhattacharya S, van der Veen F.

Hum Reprod. 2017 Nov 1;32(11):2153-2158. doi: 10.1093/humrep/dex311.


Development of the testis in pre-pubertal boys with cancer after biopsy for fertility preservation.

Uijldert M, Meißner A, de Melker AA, van Pelt AMM, van de Wetering MD, van Rijn RR, van Wely M, van der Veen F, Repping S.

Hum Reprod. 2017 Dec 1;32(12):2366-2372. doi: 10.1093/humrep/dex306.


The importance of genetic parenthood for infertile men and women.

Hendriks S, Peeraer K, Bos H, Repping S, Dancet EAF.

Hum Reprod. 2017 Oct 1;32(10):2076-2087. doi: 10.1093/humrep/dex256.


Unraveling transcriptome dynamics in human spermatogenesis.

Jan SZ, Vormer TL, Jongejan A, Röling MD, Silber SJ, de Rooij DG, Hamer G, Repping S, van Pelt AMM.

Development. 2017 Oct 15;144(20):3659-3673. doi: 10.1242/dev.152413. Epub 2017 Sep 21.


Factor V Leiden is associated with increased sperm count.

van Mens TE, Joensen UN, Bochdanovits Z, Takizawa A, Peter J, Jørgensen N, Szecsi PB, Meijers JCM, Weiler H, Rajpert-De Meyts E, Repping S, Middeldorp S.

Hum Reprod. 2017 Nov 1;32(11):2332-2339. doi: 10.1093/humrep/dex287.


Trivial role for NSMCE2 during in vitro proliferation and differentiation of male germline stem cells.

Zheng Y, Jongejan A, Mulder CL, Mastenbroek S, Repping S, Wang Y, Li J, Hamer G.

Reproduction. 2017 Sep;154(3):181-195. doi: 10.1530/REP-17-0173. Epub 2017 Jun 2.


The SUPER study: protocol for a randomised controlled trial comparing follicle-stimulating hormone and clomiphene citrate for ovarian stimulation in intrauterine insemination.

Danhof NA, van Wely M, Koks CAM, Gianotten J, de Bruin JP, Cohlen BJ, van der Ham DP, Klijn NF, van Hooff MHA, Broekmans FJM, Fleischer K, Janssen CAH, Rijn van Weert JM, van Disseldorp J, Twisk M, Traas M, Verberg MFG, Pelinck MJ, Visser J, Perquin DAM, Boks DES, Verhoeve HR, van Heteren CF, Mol BWJ, Repping S, van der Veen F, Mochtar MH.

BMJ Open. 2017 May 25;7(5):e015680. doi: 10.1136/bmjopen-2016-015680.


Cost-effectiveness of single versus double embryo transfer in IVF in relation to female age.

van Loendersloot LL, Moolenaar LM, van Wely M, Repping S, Bossuyt PM, Hompes PGA, van der Veen F, Mol BWJ.

Eur J Obstet Gynecol Reprod Biol. 2017 Jul;214:25-30. doi: 10.1016/j.ejogrb.2017.04.031. Epub 2017 Apr 17.


The acceptability of stem cell-based fertility treatments for different indications.

Hendriks S, Dancet EAF, Vliegenthart R, Repping S.

Mol Hum Reprod. 2017 Dec 1;23(12):855-863. doi: 10.1093/molehr/gax027.


Fresh versus frozen embryo transfers in assisted reproduction.

Wong KM, van Wely M, Mol F, Repping S, Mastenbroek S.

Cochrane Database Syst Rev. 2017 Mar 28;3:CD011184. doi: 10.1002/14651858.CD011184.pub2. Review.


IVF or IUI as first-line treatment in unexplained subfertility: the conundrum of treatment selection markers.

Tjon-Kon-Fat RI, Tajik P, Zafarmand MH, Bensdorp AJ, Bossuyt PMM, Oosterhuis GJE, van Golde R, Repping S, Lambers MDA, Slappendel E, Perquin D, Pelinck MJ, Gianotten J, Maas JWM, Eijkemans MJC, van der Veen F, Mol BW, van Wely M; INeS study group†.

Hum Reprod. 2017 May 1;32(5):1028-1032. doi: 10.1093/humrep/dex037.


Reply II: Embryo culture media effects.

Kleijkers SH, Mantikou E, Slappendel E, Consten D, van Echten-Arends J, Wetzels AM, van Wely M, Smits LJ, van Montfoort AP, Repping S, Dumoulin JC, Mastenbroek S.

Hum Reprod. 2017 Mar 1;32(3):717-718. doi: 10.1093/humrep/dew340. No abstract available.


Measuring Sperm DNA Fragmentation and Clinical Outcomes of Medically Assisted Reproduction: A Systematic Review and Meta-Analysis.

Cissen M, Wely MV, Scholten I, Mansell S, Bruin JP, Mol BW, Braat D, Repping S, Hamer G.

PLoS One. 2016 Nov 10;11(11):e0165125. doi: 10.1371/journal.pone.0165125. eCollection 2016. Review.


Behavioral, cognitive, and motor performance and physical development of five-year-old children who were born after intracytoplasmic sperm injection with the use of testicular sperm.

Meijerink AM, Ramos L, Janssen AJ, Maas-van Schaaijk NM, Meissner A, Repping S, Mochtar MH, Braat DD, Fleischer K.

Fertil Steril. 2016 Dec;106(7):1673-1682.e5. doi: 10.1016/j.fertnstert.2016.09.011. Epub 2016 Oct 25.


Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress.

Verver DE, Zheng Y, Speijer D, Hoebe R, Dekker HL, Repping S, Stap J, Hamer G.

Int J Mol Sci. 2016 Oct 26;17(11). pii: E1782.


Establishing reference values for age-related spermatogonial quantity in prepubertal human testes: a systematic review and meta-analysis.

Masliukaite I, Hagen JM, Jahnukainen K, Stukenborg JB, Repping S, van der Veen F, van Wely M, van Pelt AM.

Fertil Steril. 2016 Dec;106(7):1652-1657.e2. doi: 10.1016/j.fertnstert.2016.09.002. Epub 2016 Oct 4. Review.


IUI and IVF for unexplained subfertility: where did we go wrong?

Tjon-Kon-Fat RI, Bensdorp AJ, Scholten I, Repping S, van Wely M, Mol BW, van der Veen F.

Hum Reprod. 2016 Dec;31(12):2665-2667. Epub 2016 Sep 22.


Perceptions of oocyte banking from women intending to circumvent age-related fertility decline.

de Groot M, Dancet E, Repping S, Goddijn M, Stoop D, van der Veen F, Gerrits T.

Acta Obstet Gynecol Scand. 2016 Dec;95(12):1396-1401. doi: 10.1111/aogs.13019. Epub 2016 Oct 14.


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