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Items: 17

1.

Exploring genetic interaction manifolds constructed from rich single-cell phenotypes.

Norman TM, Horlbeck MA, Replogle JM, Ge AY, Xu A, Jost M, Gilbert LA, Weissman JS.

Science. 2019 Aug 23;365(6455):786-793. doi: 10.1126/science.aax4438. Epub 2019 Aug 8.

2.

A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.

Ryan KJ, White CC, Patel K, Xu J, Olah M, Replogle JM, Frangieh M, Cimpean M, Winn P, McHenry A, Kaskow BJ, Chan G, Cuerdon N, Bennett DA, Boyd JD, Imitola J, Elyaman W, De Jager PL, Bradshaw EM.

Sci Transl Med. 2017 Dec 20;9(421). pii: eaai7635. doi: 10.1126/scitranslmed.aai7635.

3.

Single-chromosome Gains Commonly Function as Tumor Suppressors.

Sheltzer JM, Ko JH, Replogle JM, Habibe Burgos NC, Chung ES, Meehl CM, Sayles NM, Passerini V, Storchova Z, Amon A.

Cancer Cell. 2017 Feb 13;31(2):240-255. doi: 10.1016/j.ccell.2016.12.004. Epub 2017 Jan 12.

4.

Genetic architecture of age-related cognitive decline in African Americans.

Raj T, Chibnik LB, McCabe C, Wong A, Replogle JM, Yu L, Gao S, Unverzagt FW, Stranger B, Murrell J, Barnes L, Hendrie HC, Foroud T, Krichevsky A, Bennett DA, Hall KS, Evans DA, De Jager PL.

Neurol Genet. 2016 Dec 21;3(1):e125. doi: 10.1212/NXG.0000000000000125. eCollection 2017 Feb.

5.

Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.

Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, De Jager PL, Bradshaw EM.

Neurol Genet. 2016 Jul 26;2(4):e90. doi: 10.1212/NXG.0000000000000090. eCollection 2016 Aug.

6.

Nucleosomes impede Cas9 access to DNA in vivo and in vitro.

Horlbeck MA, Witkowsky LB, Guglielmi B, Replogle JM, Gilbert LA, Villalta JE, Torigoe SE, Tjian R, Weissman JS.

Elife. 2016 Mar 17;5. pii: e12677. doi: 10.7554/eLife.12677.

7.

Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells.

Orent W, Mchenry AR, Rao DA, White C, Klein HU, Bassil R, Srivastava G, Replogle JM, Raj T, Frangieh M, Cimpean M, Cuerdon N, Chibnik L, Khoury SJ, Karlson EW, Brenner MB, De Jager P, Bradshaw EM, Elyaman W.

Hum Mol Genet. 2016 Jan 15;25(2):404-17. doi: 10.1093/hmg/ddv474. Epub 2015 Nov 24.

8.

CD33 modulates TREM2: convergence of Alzheimer loci.

Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, Bradshaw EM, De Jager PL.

Nat Neurosci. 2015 Nov;18(11):1556-8. doi: 10.1038/nn.4126. Epub 2015 Sep 28.

9.

Reply: To PMID 25545807.

Replogle JM, De Jager PL.

Ann Neurol. 2015 Oct;78(4):659-60. doi: 10.1002/ana.24456. Epub 2015 Aug 22. No abstract available.

PMID:
26059823
10.

A pharmacogenetic study implicates SLC9a9 in multiple sclerosis disease activity.

Esposito F, Sorosina M, Ottoboni L, Lim ET, Replogle JM, Raj T, Brambilla P, Liberatore G, Guaschino C, Romeo M, Pertel T, Stankiewicz JM, Martinelli V, Rodegher M, Weiner HL, Brassat D, Benoist C, Patsopoulos NA, Comi G, Elyaman W, Martinelli Boneschi F, De Jager PL.

Ann Neurol. 2015 Jul;78(1):115-27. doi: 10.1002/ana.24429. Epub 2015 May 14.

PMID:
25914168
11.

A cis-regulatory antisense RNA represses translation in Vibrio cholerae through extensive complementarity and proximity to the target locus.

Chang H, Replogle JM, Vather N, Tsao-Wu M, Mistry R, Liu JM.

RNA Biol. 2015;12(2):136-48. doi: 10.1080/15476286.2015.1017203.

12.

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

Replogle JM, Chan G, White CC, Raj T, Winn PA, Evans DA, Sperling RA, Chibnik LB, Bradshaw EM, Schneider JA, Bennett DA, De Jager PL.

Ann Neurol. 2015 Mar;77(3):469-77. doi: 10.1002/ana.24337.

13.

Epigenomics in translational research.

Replogle JM, De Jager PL.

Transl Res. 2015 Jan;165(1):7-11. doi: 10.1016/j.trsl.2014.09.011. Epub 2014 Oct 5. No abstract available.

14.

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.

Raj T, Rothamel K, Mostafavi S, Ye C, Lee MN, Replogle JM, Feng T, Lee M, Asinovski N, Frohlich I, Imboywa S, Von Korff A, Okada Y, Patsopoulos NA, Davis S, McCabe C, Paik HI, Srivastava GP, Raychaudhuri S, Hafler DA, Koller D, Regev A, Hacohen N, Mathis D, Benoist C, Stranger BE, De Jager PL.

Science. 2014 May 2;344(6183):519-23. doi: 10.1126/science.1249547.

15.

Interindividual variation in human T regulatory cells.

Ferraro A, D'Alise AM, Raj T, Asinovski N, Phillips R, Ergun A, Replogle JM, Bernier A, Laffel L, Stranger BE, De Jager PL, Mathis D, Benoist C.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):E1111-20. doi: 10.1073/pnas.1401343111. Epub 2014 Mar 7.

16.

CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility.

Raj T, Ryan KJ, Replogle JM, Chibnik LB, Rosenkrantz L, Tang A, Rothamel K, Stranger BE, Bennett DA, Evans DA, De Jager PL, Bradshaw EM.

Hum Mol Genet. 2014 May 15;23(10):2729-36. doi: 10.1093/hmg/ddt666. Epub 2013 Dec 30.

17.

Common risk alleles for inflammatory diseases are targets of recent positive selection.

Raj T, Kuchroo M, Replogle JM, Raychaudhuri S, Stranger BE, De Jager PL.

Am J Hum Genet. 2013 Apr 4;92(4):517-29. doi: 10.1016/j.ajhg.2013.03.001. Epub 2013 Mar 21.

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